Search results for "computing"

showing 10 items of 25279 documents

IRS-2 deficiency impairs NMDA receptor-dependent long-term potentiation

2011

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License.-- et al.

medicine.medical_specialtyPatch-Clamp TechniquesCognitive Neurosciencemedicine.medical_treatmentBlotting WesterneducationHippocampusComputingMilieux_LEGALASPECTSOFCOMPUTINGNeurotransmissionBiologyHippocampusReceptors N-Methyl-D-AspartateSynaptic TransmissionMiceCellular and Molecular NeuroscienceInternal medicinemedicineAnimalsImmunoprecipitationlong-term potentiationMice Knockoutsynaptic plasticitydiabetesInsulinDiabetesLong-term potentiationArticlesNMDA receptorIRS2insulin receptor signalingSynaptic fatigueEndocrinologynervous systemSynaptic plasticityInsulin Receptor Substrate ProteinsNMDA receptorFemaleNeuroscienceCerebral Cortex
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Comparison of the ability of alternative birthweight and fetal weight standards to identify preterm newborns at increased risk of perinatal death

2013

Objective To compare prediction of perinatal deaths among preterm infants based on fetal weight standards versus a new subpopulation-based birthweight standard. Design Population-based cohort study. Setting France. Population A total of 9100 preterm singletons, born between 24 and 36 weeks of gestation in 2000–09, in Burgundy (France). Methods We first classified all newborns as either small for gestational age (SGA) or not, based on alternative fetal weight or birthweight standards, including a new birthweight standard that excludes infants born to mothers with disease related to the weight of a fetus. Based on discrepancies between the different classifications, we then divided the newbor…

medicine.medical_specialtyPediatricsPopulation[ SDV.MHEP.PED ] Life Sciences [q-bio]/Human health and pathology/PediatricsIntrauterine growth restrictionRisk AssessmentCohort StudiesFetal Development03 medical and health sciences0302 clinical medicine030225 pediatricsMedicineBirth WeightHumansHospital MortalityeducationFetal Deathreproductive and urinary physiologyPerinatal MortalityComputingMilieux_MISCELLANEOUSFetuseducation.field_of_study[SDV.MHEP.PED]Life Sciences [q-bio]/Human health and pathology/Pediatrics030219 obstetrics & reproductive medicinebusiness.industryObstetricsInfant NewbornObstetrics and GynecologyReference StandardsStillbirthmedicine.diseaseConfidence interval3. Good healthFetal WeightRelative riskInfant Small for Gestational AgeGestationSmall for gestational agePremature BirthFrancebusinessInfant PrematureCohort study
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Endovascular management of a giant symptomatic gluteal artery aneurysm with selective arterial embolization

2017

A 78-year-old female presented to our department with pain and swelling in the left gluteal region. Physical examination revealed a large tender swelling in the left gluteal area simulating an abscess. However, pulsation was observed over the swelling that raised the suspicion of a vascular lesion. Therefore, contrast-enhanced computed tomography (CT) was done before trying any intervention. The scan demonstrated a large aneurysm originating from the left superior gluteal artery measuring 65 mm × 38 mm with a small intra-pelvic component and large extra-pelvic component in the gluteal area ( Figure 1 ).

medicine.medical_specialtyPhysical examination[SDV.IB.MN]Life Sciences [q-bio]/Bioengineering/Nuclear medicine030204 cardiovascular system & hematology[ SDV.IB.MN ] Life Sciences [q-bio]/Bioengineering/Nuclear medicine03 medical and health sciences0302 clinical medicineAneurysmmedicine[INFO.INFO-IM]Computer Science [cs]/Medical ImagingRadiology Nuclear Medicine and imaging030212 general & internal medicineLeft gluteal regionGluteal ArteryAbscessLetter to the EditorComputingMilieux_MISCELLANEOUSmedicine.diagnostic_test[ INFO.INFO-IM ] Computer Science [cs]/Medical Imagingbusiness.industryArterial Embolizationmedicine.diseaseLeft superior gluteal arterySurgerybody regionsRadiologybusinessGluteal area
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The story models of physiotherapy students’ professional development. Narrative research

2014

The aim of this article is to investigate students’ narratives about their professional development process. This research brings new kind of knowledge to continuing learning, developing education and planning the curriculum in physiotherapy education. The European Qualification Framework (EQF) defines learning competences in education; qualitative research has a narrative approach. The material consists of eight voluntarily participating physiotherapy students’ portfolios written during their whole study time. The longitudinal data describes them as learners and their development process. The major findings are four main episodes in professional development: the previous studies, a new way…

medicine.medical_specialtyPhysiotherapy educationLongitudinal dataProcess (engineering)business.industryphysiotherapy studentProfessional developmentta3141Physical Therapy Sports Therapy and Rehabilitationnarrative researchNarrative inquiryammatillinen kehitysPedagogyComputingMilieux_COMPUTERSANDEDUCATIONPhysical therapymedicineta516Narrativeuniversity of applied sciencesbusinessCurriculumQualitative researchEuropean Journal of Physiotherapy
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Development of a Protocol for CCD Calibration: Application to a Multispectral Imaging System

2005

In this paper we describe in detail a method for calibrating a CCD-based camera. The calibration aims to remove both temporal and systematic noises introduced by the sensor, electronics, and optics after which we can correct the non-linearity of its response. For the non-linearity correction we use a simple and powerful approach consisting on a complementary approach between a polynomial fitting and an LUT based algorithm. The proposed methodology is accurate in the sense that it takes into account individual characteristics of each pixel. In each pixel, systematic noises are measured through acquiring offset images, thermal images, and FlatField images. A rigorous protocol for acquiring th…

medicine.medical_specialtyPixelComputer sciencebusiness.industryMultispectral imageComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISIONSpectral imagingComputer Science::Computer Vision and Pattern RecognitionmedicineCalibrationComputer visionArtificial intelligencebusinessOptical filterInternational Journal of Robotics and Automation
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Alteration of plasmalogens in erythrocytes of patients with diabetic retinopathy

2011

Purpose Plasmalogens are phospholipids characterized by a vinyl ether bond and the preferential esterification of polyunsaturated fatty acids (PUFA). We have shown that the lack of plasmalogens leads to abnormal retinal vascularisation. Because we hypothesize that plasmalogens are negative regulators of vascular development, we aimed to check their circulating levels in patients having a retinal pathology with vascular proliferation. Methods Blood samples were collected from 4 control subjects and 42 patients having proliferative or non-proliferative diabetic retinopathy (DR). Patients were classified according to the stage of DR. The plasmalogen content and the fatty acid composition of er…

medicine.medical_specialtyPlasmalogenBiologychemistry.chemical_compoundInternal medicinemedicineIn patient[SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory OrgansComputingMilieux_MISCELLANEOUSchemistry.chemical_classificationRetina[SDV.MHEP] Life Sciences [q-bio]/Human health and pathologyRetinalGeneral MedicineDiabetic retinopathyControl subjectsmedicine.disease3. Good healthOphthalmologyEndocrinologymedicine.anatomical_structureBiochemistrychemistryDocosahexaenoic acid[SDV.MHEP.OS] Life Sciences [q-bio]/Human health and pathology/Sensory Organslipids (amino acids peptides and proteins)[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyPolyunsaturated fatty acid
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Medications between psychiatric and addictive disorders

2016

International audience; Introduction : Many epidemiological studies have revealed a frequent co-occurrence of psychiatric and substance use disorders. The term used in the literature to refer to this co-occurrence is dual diagnosis. The high prevalence of dual diagnosis has led physicians to observe the effects of medication prescribed to treat psychiatric disorders on the co-occurring substance use disorder and vice versa. The concept of medications between psychiatric and addictive disorders stems from these clinical observations, alongside which, however, it has developed from the observation that both psychiatric and substance use disorders share common neurobiological pathways and trig…

medicine.medical_specialtyPsychotherapistSubstance-Related Disordersmedia_common.quotation_subject[SDV]Life Sciences [q-bio][ SDV.MHEP.PSM ] Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental healthAddictionModafinilMirtazapine[ SCCO.PSYC ] Cognitive science/Psychology03 medical and health sciences0302 clinical medicineCognitionEpidemiology of child psychiatric disordersmedicineAnimalsHumansDual diagnosisMedical prescriptionPsychiatryClozapineBiological PsychiatryDepression (differential diagnoses)ComputingMilieux_MISCELLANEOUSmedia_commonPharmacologyPsychotropic DrugsDepressionAddictionmedicine.disease3. Good health030227 psychiatrySubstance abuseClinical researchSchizophreniaDiagnosis Dual (Psychiatry)[SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health[SCCO.PSYC]Cognitive science/PsychologySchizophreniaDual diagnosisPsychologyPsychiatric disorders030217 neurology & neurosurgery
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Effects of atypical antipsychotics on neurocognition in euthymic bipolar patients

2010

International audience; n.a

medicine.medical_specialtyPsychotherapistlcsh:RC435-571[SDV.MHEP.PSM] Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health3. Good health030227 psychiatry03 medical and health sciencesPsychiatry and Mental health0302 clinical medicinelcsh:PsychiatryForensic psychiatry[SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental healthMeeting AbstractmedicinePsychopharmacologyPsychiatryPsychologyNeurocognitive030217 neurology & neurosurgeryGeriatric psychiatryComputingMilieux_MISCELLANEOUS
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Perception of improved state of health and subjective quality of life in Crohn's disease patients treated with Infliximab.

2009

International audience; UNLABELLED: BACKGROUND AND AIMS AND METHOD: Although Infliximab is a very potent therapy of refractory Crohn's disease, its administration requires iterative infusions in hospital and there are concerns regarding its long-term safety. The aim of this study was to assess in a sample of 51 patients suffering from CD the impact of type of treatment (intravenous Infliximab versus conventional therapy without Infliximab) on the evaluation of the state of health (CGI) and the quality of life (MOS-SF36). Secondary variables were also assessed: the impact of depression (MADRS), the impact of activity of the disease (Harvey-Bradshaw Index). RESULTS: Overall, the assessments m…

medicine.medical_specialtySF-36State of health[SHS.PSY]Humanities and Social Sciences/PsychologyDisease03 medical and health sciences[ SHS.PSY ] Humanities and Social Sciences/Psychology0302 clinical medicineQuality of lifeRefractoryInternal medicinemedicine030212 general & internal medicineDepression (differential diagnoses)ComputingMilieux_MISCELLANEOUSCrohn's diseasebusiness.industry[CHIM.ORGA]Chemical Sciences/Organic chemistryGastroenterologyGeneral Medicinemedicine.diseaseInfliximab3. Good healthPhysical therapy030211 gastroenterology & hepatologybusinessmedicine.drug
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Modulation of hippocampal acetylcholine release after fimbria-fornix lesions and septal transplantation in rats

1997

Abstract Female Long–Evans rats sustained electrolytic lesions of the fimbria and the dorsal fornix causing a partial lesion of the septohippocampal pathway. Two weeks later, the rats received intra-hippocampal grafts of fetal septal cell suspensions. Nine to twelve months later, the release of acetylcholine (ACh) in the hippocampus of sham-operated, lesion-only and grafted rats was measured by microdialysis. The extent of cholinergic (re)innervation was determined by acetylcholinesterase (AChE) staining and densitometry. In both lesion-only and grafted rats, the ratio of ACh release to AChE staining intensity was increased as compared to sham-operated rats, indicating a loss of endogenous …

medicine.medical_specialtySciences du Vivant [q-bio]/Neurosciences [q-bio.NC]Microdialysis[SDV]Life Sciences [q-bio][SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/NeurobiologyScopolamineMuscarinic AntagonistsHippocampal formationBiologySerotonergicHippocampus03 medical and health scienceschemistry.chemical_compound0302 clinical medicineInternal medicineNeural PathwaysmedicineAnimalsBrain Tissue TransplantationCholinergic neuronNeurotransmitterComputingMilieux_MISCELLANEOUS030304 developmental biology0303 health sciences8-Hydroxy-2-(di-n-propylamino)tetralinGeneral NeuroscienceFornixMuscarinic antagonistRats Inbred StrainsAcetylcholineRatsEndocrinologychemistryCholinergic FibersAnesthesiaReceptors SerotoninCholinergicRaphe NucleiFemaleSeptal Nuclei[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]Receptors Serotonin 5-HT1030217 neurology & neurosurgeryAcetylcholinemedicine.drug
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