6533b82afe1ef96bd128ba35

RESEARCH PRODUCT

Medications between psychiatric and addictive disorders

Jean-philippe LangBenoit TrojakBrigitte L. KiefferBrigitte L. KiefferLaurence LalanneElisabeth BaconPierre-eric Lutz

subject

medicine.medical_specialtyPsychotherapistSubstance-Related Disordersmedia_common.quotation_subject[SDV]Life Sciences [q-bio][ SDV.MHEP.PSM ] Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental healthAddictionModafinilMirtazapine[ SCCO.PSYC ] Cognitive science/Psychology03 medical and health sciences0302 clinical medicineCognitionEpidemiology of child psychiatric disordersmedicineAnimalsHumansDual diagnosisMedical prescriptionPsychiatryClozapineBiological PsychiatryDepression (differential diagnoses)ComputingMilieux_MISCELLANEOUSmedia_commonPharmacologyPsychotropic DrugsDepressionAddictionmedicine.disease3. Good health030227 psychiatrySubstance abuseClinical researchSchizophreniaDiagnosis Dual (Psychiatry)[SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health[SCCO.PSYC]Cognitive science/PsychologySchizophreniaDual diagnosisPsychologyPsychiatric disorders030217 neurology & neurosurgery

description

International audience; Introduction : Many epidemiological studies have revealed a frequent co-occurrence of psychiatric and substance use disorders. The term used in the literature to refer to this co-occurrence is dual diagnosis. The high prevalence of dual diagnosis has led physicians to observe the effects of medication prescribed to treat psychiatric disorders on the co-occurring substance use disorder and vice versa. The concept of medications between psychiatric and addictive disorders stems from these clinical observations, alongside which, however, it has developed from the observation that both psychiatric and substance use disorders share common neurobiological pathways and trigger common cognitive disorders. This has led researchers to develop medications on the basis of neurobiological and cognitive rationales.Material and method : In our article, we review peculiar medications based on neurobiological and cognitive rationales and that have an impact in both psychiatric and addictive disorders.Results : We highlight how interesting these new prescriptions are for clinical observation and for the treatment of patients suffering from dual diagnosis.Conclusion : We then go on to discuss the interest in them from the perspective of clinical practice and clinical research, in that the development of medications to treat dual diagnosis helps to further our knowledge of both psychiatric and substance use disorders.

https://hal-univ-bourgogne.archives-ouvertes.fr/hal-01489014