Search results for "concurrent"
showing 10 items of 123 documents
A methodology for the reduction of imprecision in the engineering process
1997
Abstract Engineering design is characterized by a high level of imprecision, vague parameters, and ill-defined relationships. In design, imprecision reduction must occur to arrive at a final product specification. Few design systems exist for adequately representing design imprecision, and formally reducing it to precise values. Fuzzy set theory has considerable potential for addressing the imprecision in design. However, it lacks a formal methodology for system development and operation. One repercussion of this is that imprecision reduction is, at present, implemented in a relatively ad-hoc manner. The main contribution of this paper is to introduce a methodology called precision converge…
CUDASW++ 3.0: accelerating Smith-Waterman protein database search by coupling CPU and GPU SIMD instructions
2013
Background The maximal sensitivity for local alignments makes the Smith-Waterman algorithm a popular choice for protein sequence database search based on pairwise alignment. However, the algorithm is compute-intensive due to a quadratic time complexity. Corresponding runtimes are further compounded by the rapid growth of sequence databases. Results We present CUDASW++ 3.0, a fast Smith-Waterman protein database search algorithm, which couples CPU and GPU SIMD instructions and carries out concurrent CPU and GPU computations. For the CPU computation, this algorithm employs SSE-based vector execution units as accelerators. For the GPU computation, we have investigated for the first time a GPU …
A Nondifferentiable Optimization Approach to Ratio-Cut Partitioning
2003
We propose a new method for finding the minimum ratio-cut of a graph. Ratio-cut is NP-hard problem for which the best previously known algorithm gives an O(log n)-factor approximation by solving its dually related maximum concurrent flow problem.We formulate the minimum ratio-cut as a certain nondifferentiable optimization problem, and show that the global minimum of the optimization problem is equal to the minimum ratio-cut. Moreover, we provide strong symbolic computation based evidence that any strict local minimum gives an approximation by a factor of 2. We also give an efficient heuristic algorithm for finding a local minimum of the proposed optimization problem based on standard nondi…
Reliability and concurrent validity of the Velowin optoelectronic system to measure movement velocity during the free-weight back squat
2018
The objective of this study was to explore the reliability and concurrent validity of the Velowin optoelectronic system to measure movement velocity during the free-weight back squat exercise. Thirty-one men (age = 27.5 ± 3.2 years; body height = 1.76 ± 0.15 m; body mass: 78.3 ± 7.6 kg) were evaluated in a single session against five different loads (20, 40, 50, 60 and 70 kg) and three velocity variables (mean velocity, mean propulsive velocity and maximum velocity) were recorded simultaneously by a linear velocity transducer (T-Force; gold-standard) and a camera-based optoelectronic system (Velowin). The main findings revealed that (1) the three velocity variables were determined with a h…
Experimental Study of Six Different Implementations of Parallel Matrix Multiplication on Heterogeneous Computational Clusters of Multicore Processors
2010
Two strategies of distribution of computations can be used to implement parallel solvers for dense linear algebra problems for Heterogeneous Computational Clusters of Multicore Processors (HCoMs). These strategies are called Heterogeneous Process Distribution Strategy (HPS) and Heterogeneous Data Distribution Strategy (HDS). They are not novel and have been researched thoroughly. However, the advent of multicores necessitates enhancements to them. In this paper, we present these enhancements. Our study is based on experiments using six applications to perform Parallel Matrix-matrix Multiplication (PMM) on an HCoM employing the two distribution strategies.
The Impact of Radiotherapy Protocol Adherence on the Treatment Outcome in Patients With Locally Advanced NSCLC Treated With Concurrent Chemoradiation…
2021
PURPOSE/OBJECTIVE(S) The success of intensification and personalization of the curative treatment of non-small cell lung cancer (NSCLC) is strongly associated with the precision in radiotherapy (RT) treatment, which must therefore follow high standards. Herein we evaluate the impact of RT protocol adherence in the prospective international multicenter trial on curative treatment of NSCLC. MATERIALS/METHODS In the open-label, randomized, controlled PET-Plan trial, patients with inoperable NSCLC were randomized at a 1:1 ratio regarding the target volume delineation informed by ¹⁸F-FDG PET and CT plus elective nodal irradiation (Arm A) or target volumes informed by PET alone (Arm B) and receiv…
Fludarabine combined with radiotherapy in patients with locally advanced NSCLC lung carcinoma: a phase I study
2011
Abstract Background and purpose Fludarabine is an adenine nucleoside analogue that has significant activity in hematological malignancies and has shown promising activity in combination with radiation in preclinical solid tumor models. We designed a phase I trial exploring concurrent fludarabine and radiotherapy in patients with advanced non-small cell lung cancer (NSCLC) to determine the maximum tolerated dose (MTD) of fludarabine given with concurrent irradiation. Materials and methods Thirteen patients with stage IIIB NSCLC received thoracic irradiation of 60 Gy. Fludarabine was administered during the 5th and 6th week of radiotherapy. Doses started at 10 mg/m2 per day and increased by s…
Development and validation of the Brief Parental Burnout Scale (BPBS).
2021
Since parental burnout can have detrimental consequences for parents, couples, and children, easy-to-use, reliable, and valid practical tools for the early detection of parental burnout are required. We developed and validated a brief scale to identify burned-out parents and parents at burnout risk. In Study 1, we developed the 5-item Brief Parental Burnout scale (BPBs) based on the gold standard measure of parental burnout, the Parental Burnout Assessment (PBA). We applied Item Response Theory Graded Response Model (GRM) analyses on the data of 1,725 Finnish parents. Compared against the PBA total score, the five selected items showed both high sensitivity and specificity in screening pare…
Adaptation and Psychometric Properties of the Scale of Positive and Negative Experience (SPANE) in the General Colombian Population
2021
(1) Background: Diener’s Scale of Positive and Negative Experiences (SPANE) assesses the presence and intensity of positive and negative affects, since these are considered basic aspects of the study of well-being. This article studies its psychometric properties in the general Colombian population. (2) We conducted a cross-sectional study of a sample of 1255 Colombians and we used structural equation modeling to confirm the bifactor structure. Additionally, we studied invariance by gender, and convergent and concurrent validity. (3) We found acceptable fit indicators for the bifactor model (CFI = 0.889, RMSEA = 0.046, SRMR = 0.059) as well as for the convergent (CFI = 0.909, RMSEA = 0.050,…
Brief report: Assessing dispositional optimism in adolescence – Factor structure and concurrent validity of the Life Orientation Test – Revised
2014
Dispositional optimism is an individual difference promoting psychosocial adjustment and well-being during adolescence. Dispositional optimism was originally defined as a one-dimensional construct; however, empirical evidence suggests two correlated factors in the Life Orientation Test - Revised (LOT-R).The main aim of the study was to evaluate the dimensionality of the LOT-R. This study is the first attempt to identify the best factor structure, comparing congeneric, two correlated-factor, and two orthogonal-factor models in a sample of adolescents. Concurrent validity was also assessed.The results demonstrated the superior fit of the two orthogonal-factor model thus reconciling the one-di…