Search results for "consequence"

showing 10 items of 137 documents

Partial Sleep Restriction Activates Immune Response-Related Gene Expression Pathways: Experimental and Epidemiological Studies in Humans

2013

Epidemiological studies have shown that short or insufficient sleep is associated with increased risk for metabolic diseases and mortality. To elucidate mechanisms behind this connection, we aimed to identify genes and pathways affected by experimentally induced, partial sleep restriction and to verify their connection to insufficient sleep at population level. The experimental design simulated sleep restriction during a working week: sleep of healthy men (N = 9) was restricted to 4 h/night for five nights. The control subjects (N = 4) spent 8 h/night in bed. Leukocyte RNA expression was analyzed at baseline, after sleep restriction, and after recovery using whole genome microarrays complem…

MaleTBX21NF-KAPPA-Blcsh:MedicineNK cellsBioinformaticskokeellinen tutkimusReceptors G-Protein-Coupled0302 clinical medicineCARDIOMETABOLIC RISKLeukocytesta319geeniekspressiolcsh:Scienceta515Sleep restrictionRegulation of gene expression0303 health sciencesMultidisciplinaryNATURAL-KILLERNF-kappa Bta3142Sleep in non-human animalsC-REACTIVE PROTEIN3. Good healthMACROPHAGE APOPTOSISINSUFFICIENT SLEEPSTAT1 Transcription FactorCARDIOVASCULAR-DISEASEimmuunivasteProteoglycansmedicine.symptomResearch ArticleAdulteducationENDOPLASMIC-RETICULUMMETABOLIC CONSEQUENCESSyntaxin 16Biologyepidemiologinen tutkimusuni (lepotila)03 medical and health sciencesImmune systemmedicineHumans030304 developmental biologyTOLL-LIKE RECEPTORSB cellsuniMicroarray analysis techniquesGene Expression Profilingsytokiinitlcsh:RMicroarray AnalysisGene expression profilingSleep deprivationGene Expression RegulationImmunologyRNASleep Deprivationlcsh:Q3111 BiomedicineT-Box Domain ProteinsReceptors Transforming Growth Factor beta030217 neurology & neurosurgery
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PASSAGE OBLIGATOIRE AUX NORMES COMPTABLES IAS/IFRS, CONTRAINTES EN LIQUIDITE ET RATIONNEMENT DU CREDIT : UNE ETUDE EMPIRIQUE DANS L'INDUSTRIE BANCAIR…

2012

Financial theory indicates that banks dependent on external resources and/or financially fragile have more difficulties in refinancing their operations of credit supply, due to the informational problems they face and/or they cause. In this context, this study tests the hypothesis that the mandatory adoption by banks of the IAS/IFRS accounting standards, known to be of higher quality, leads to an increase in the quantity of loans granted by banks constrained in liquidity, all else equal. Based on a sample of European banks, between 2003 and 2008, we obtain results in favour of this hypothesis.

Mandatory adoption of IAS/IFRS accounting standardsMandatory adoption of IAS/IFRS accounting standardseconomic consequencesbankscredit rationingAdoption obligatoire des normes comptables IAS/IFRSconséquences économiquesbanquesrationnement du créditeconomic consequencesbanques[SHS.GESTION]Humanities and Social Sciences/Business administrationAdoption obligatoire des normes comptables IAS/IFRScredit rationingconséquences économiquesrationnement du crédit[SHS.GESTION] Humanities and Social Sciences/Business administration[ SHS.GESTION ] Humanities and Social Sciences/Business administrationbanks
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Perceived major experiences of discrimination, ethnic group, and risk of psychosis in a six-country case-control study

2021

AbstractBackgroundPerceived discrimination is associated with worse mental health. Few studies have assessed whether perceived discrimination (i) is associated with the risk of psychotic disorders and (ii) contributes to an increased risk among minority ethnic groups relative to the ethnic majority.MethodsWe used data from the European Network of National Schizophrenia Networks Studying Gene-Environment Interactions Work Package 2, a population-based case−control study of incident psychotic disorders in 17 catchment sites across six countries. We calculated odds ratios (OR) and 95% confidence intervals (95% CI) for the associations between perceived discrimination and psychosis using mixed-…

Mediation (statistics)LIFE EVENTSMIGRATIONPopulationEthnic groupLogistic regressionpsychosiOdds03 medical and health sciences0302 clinical medicineMINORIAS ÉTNICASSCHIZOPHRENIAMedicinepsychosisfirst-episodeeducationCase−controlApplied PsychologyTRAUMACase-control discrimination first-episode minority ethnic group multi-country psychosis psychotic disorderFirst episodemulti-countryeducation.field_of_studyminority ethnic groupCONSEQUENCESbusiness.industryAbsolute risk reductionPATHWAYSOdds ratiopsychotic disorderCase-controlMEDIATION ANALYSIS030227 psychiatryPsychiatry and Mental health[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]HEALTHbusinessCHILDHOOD ADVERSITIES030217 neurology & neurosurgeryDemographydiscrimination
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Abnormal expansion of segmented filamentous bacteria in the gut

2011

Human intestinal microbiota create a complex polymicrobial ecology characterized by high population density, wide diversity, and complexity of interactions. Any imbalance of this complex intestinal microbiome, both qualitative and quantitative, might have serious health consequences including an increase in the number and/or alteration in the type of bacteria in the upper gastrointestinal tract, which is referred to as small intestinal bacterial overgrowth (SIBO) syndrome. SIBO is frequently found in persons fulfilling criteria for irritable bowel syndrome (IBS), and the large overlapping of symptoms of these two pathological conditions led some authors to believe that IBS is secondary to S…

Microbiology (medical)PathogenesisSettore MED/07 - Microbiologia E Microbiologia ClinicaSettore MED/18 - Chirurgia GeneraleHealth consequencesSettore BIO/13 - Biologia ApplicataSegmented filamentous bacteriaEcology (disciplines)Intestinal MicrobiomeChronic intestinal desease overgrowth segmented filamentous bacteriaBiologyMicrobiologyReviews in Medical Microbiology
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Role of RNA Guanine Quadruplexes in Favoring the Dimerization of SARS Unique Domain in Coronaviruses

2020

ABSTRACTCoronaviruses may produce severe acute respiratory syndrome (SARS). As a matter of fact, a new SARS-type virus, SARS-CoV-2, is responsible of a global pandemic in 2020 with unprecedented sanitary and economic consequences for most countries. In the present contribution we study, by all-atom equilibrium and enhanced sampling molecular dynamics simulations, the interaction between the SARS Unique Domain and RNA guanine quadruplexes, a process involved in eluding the defensive response of the host thus favoring viral infection of human cells. Our results evidence two stable binding modes involving an interaction site spanning either the protein dimer interface or only one monomer. The …

Models Molecular0301 basic medicineLetterSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)DimerPneumonia ViralCoronaviruProtein dimerMolecular Dynamics SimulationViral infection01 natural sciencesVirusBetacoronavirus03 medical and health scienceschemistry.chemical_compound0302 clinical medicine0103 physical sciencesG-QuadruplexeHumans[CHIM]Chemical SciencesGeneral Materials Science030212 general & internal medicinePhysical and Theoretical ChemistryPandemicsEconomic consequences030304 developmental biology0303 health sciences010304 chemical physicsBetacoronaviruSARS-CoV-2ChemistryCoronavirus InfectionRational designCOVID-19RNASpike Glycoprotein3. Good healthG-Quadruplexes030104 developmental biologySettore CHIM/03 - Chimica Generale E InorganicaSpike Glycoprotein CoronavirusBiophysicsRNA ViralCoronavirus InfectionsGuanine-QuadruplexesDimerizationProtein Binding
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Engaging in upward and downward comparisons as a determinant of relative deprivation at work

2003

A longitudinal study was conducted among 93 nurses to determine the role of comparing one's performance with that of one's colleagues in the increase versus decrease of perceived relative deprivation at work over a period of one year. Relative deprivation at T2 had increased particularly among those high in social comparison orientation (Gibbons & Buunk, 1999) who at T1 (1) more frequently engaged in upward comparisons; (2) more frequently derived positive as well as negative feelings from such comparisons; and (3) more frequently derived negative feelings from downward comparison. Moreover, engaging in downward comparison also led to an increase in perceived relative deprivation at T2.…

Organizational Behavior and Human Resource ManagementLongitudinal studySocial comparison orientationINFORMATIONSATISFACTIONmedia_common.quotation_subjectSOCIAL-COMPARISON ORIENTATIONAFFECTIVE CONSEQUENCESSELF-ESTEEMCONTRASTADJUSTMENTmedicine.disease_causenursesrelationships within organizationEducationDevelopmental psychologymedicinesocial comparison orientationLife-span and Life-course StudiesRelative deprivationPREDICTORSApplied Psychologyrelative deprivationA determinantmedia_commonSocial comparison theoryWork (physics)Self-esteemPERFORMANCEDEPRESSIONFeelingPsychologyJournal of Vocational Behavior
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Small changes, big impacts: Geographic expansion in small-scale fisheries

2020

Abstract Small-scale fisheries are an important, yet neglected, millenarian activity that has been undergoing significant changes that threaten its future. Understanding how this activity is spatially distributed and the factors that drive its use of the marine space over time can shed some light on how fishing efforts and their impacts have moved over different parts of coastal marine ecosystems. This study investigated changes to the spatial distribution of small-scale fisheries along the Brazilian equatorial region between 1994 and 2014 and the factors, from ecological to socioeconomic, that influenced this shift. Bayesian hierarchical spatial models were used together with environmental…

Overcapacity0106 biological sciencesSmall-scale fisheriesOverfishing010604 marine biology & hydrobiologyFishingSede Central IEO04 agricultural and veterinary sciencesAquatic ScienceSpatial distribution01 natural sciencesEcological collapseFisheryGeographyFisheries geographical expansionSpatial fisheries distribution040102 fisheries0401 agriculture forestry and fisheriesSocial consequenceSubmarine pipelineMarine ecosystemPesqueríasSocioeconomic statusBayesian modelsFisheries Research
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Two Paths to Logical Consequence: Pieri and the Peano School

2021

This chapter1 has two main goals. First, it will explore the “negative” avenue leading from the concepts of independence and consistency to that of logical consequence.

Peano axiomsIndependence (mathematical logic)Consistency (knowledge bases)Logical consequenceMathematical economicsMathematics
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Fostering creative thinking : the role of primary teachers

2014

Τα τελευταία χρόνια παρατηρείται μια αυξανόμενη απαίτηση για δημιουργικότητα σε όλους τους τομείς της ανθρώπινης δραστηριότητας. Η πρωτοβάθμια εκπαίδευση πασχίζει να συμβαδίσει με τις νέες κοινωνικοοικονομικές ανάγκες και να προετοιμάσει τους δημιουργικούς πολίτες του μέλλοντος. Αν και οι εκπαιδευτικοί της πρωτοβάθμιας εκπαίδευσης παίζουν καθοριστικό ρόλο, άλλοτε θετικό και άλλοτε αρνητικό, στην καλλιέργεια της δημιουργικότητας των μαθητών, λίγες έρευνες έχουν διεξαχθεί σχετικά με τη συμβολή τους στην καλλιέργεια της δημιουργικής σκέψης των μαθητών και τις απόψεις τους για το θέμα αυτό. Η θεμελιωμένη γνώση (situated knowledge) των Ελλήνων εκπαιδευτικών πρωτοβάθμιας εκπαίδευσης και η εμπειρί…

Pedagogycreativity consequences analytical frameworkprimary teachers' conceptions of creativitycreativity metasciencefostering creative thinkingimplicit creativity theoriesCreative thinkingcreativity recommendationsPsychologyteacher trainingcollaborative creativitymanifold thinkingcreativity in primary education
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WHEN DEDUCTION LEADS TO BELIEF

1995

The paper questions the common assumption that rational individuals believe all propositions which they know to be logical consequences of their other beliefs: although we must acknowledge the truth of a proposition which is a deductive consequence of our beliefs, we may not genuinely believe it. This conclusion is defended by arguing that some familiar counterexamples to the claim that knowledge is justified true belief fail because they involve propositions which are not really believed. Beliefs guide conduct or issue in assertion by answering questions which arise in the course of deliberation and conversation, but the troublesome cases present propositions which do not present the agent…

PhilosophyTheoryofComputation_MATHEMATICALLOGICANDFORMALLANGUAGESmedia_common.quotation_subjectAssertionConversationPropositionRationalityPsychologyDeliberationLogical consequenceCounterexamplemedia_commonEpistemologyRatio
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