Search results for "consumption"

showing 10 items of 1796 documents

Bleomycin genotoxicity alteration by glutathione and cytochrome P-450 cellular content in respiratory proficient and deficient strains of Saccharomyc…

1999

The genotoxic effects of the antiblastic drug bleomycin were studied in the D7 strain of Saccharomyces cerevisiae and on its derivative mitochondrial mutant rho degree at different cellular concentrations of two drug metabolizing systems, glutathione (GSH) and cytochrome P-450. Bleomycin mutagenic activity was evaluated as frequencies of mitotic gene conversion, reversion and total aberrations under different physiological conditions. In the D7 strain, petite mutant induction was also detected. This is important due to the role of the mitochondrial genome in cancer induction, ageing and degenerative diseases. Both strains showed higher convertant than revertant induction. At high cytochrome…

CytochromeHealth Toxicology and MutagenesisSaccharomyces cerevisiaeMutantRespiratory chainCell Culture TechniquesSaccharomyces cerevisiaeToxicologymedicine.disease_causeBleomycinDNA Mitochondrialchemistry.chemical_compoundBleomycinOxygen ConsumptionCytochrome P-450 Enzyme SystemGeneticsmedicinePoint MutationGenetics (clinical)Chromosome AberrationsRecombination GeneticbiologyDose-Response Relationship DrugMutagenicity TestsCytochrome P450Glutathionebiology.organism_classificationGlutathioneBiochemistrychemistryMutagenesisbiology.proteinGenotoxicityMutagenesis
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Availability of O 2 as a Substrate in the Cytoplasm of Bacteria under Aerobic and Microaerobic Conditions

1998

ABSTRACT The growth rates of Pseudomonas putida KT2442 and mt-2 on benzoate, 4-hydroxybenzoate, or 4-methylbenzoate showed an exponential decrease with decreasing oxygen tensions (partial O 2 tension [pO 2 ] values). The oxygen tensions resulting in half-maximal growth rates were in the range of 7 to 8 mbar of O 2 (corresponding to 7 to 8 μM O 2 ) (1 bar = 10 5 Pa) for aromatic compounds, compared to 1 to 2 mbar for nonaromatic compounds like glucose or succinate. The decrease in the growth rates coincided with excretion of catechol or protocatechuate, suggesting that the activity of the corresponding oxygenases became limiting. The experiments directly establish that under aerobic and micr…

CytoplasmOxygenasePhysiology and MetabolismDiffusionCatecholsParabenschemistry.chemical_elementBenzoatesMicrobiologyOxygenDioxygenaseschemistry.chemical_compoundOxygen ConsumptionCatechol 12-dioxygenaseMolecular BiologyBenzoic acidbiologyPseudomonas putidaSubstrate (chemistry)SuccinatesBenzoic Acidbiology.organism_classificationAerobiosisCatechol 12-DioxygenasePseudomonas putidaGlucoseBiochemistrychemistryCytoplasmOxygenasesBiophysicsJournal of Bacteriology
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Dynamics and deviants related to drug use

2014

The chapter focuses on drug related dynamics and interactional processes in drug's use and cinsumption

DEVIANT BEHAVIORCONSUMPTION'S DYNAMICSSettore SPS/12 - Sociologia Giuridica Della Devianza E Mutamento SocialeDRUG MARKET
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Egg consumption and human health: an umbrella review of observational studies

2019

Egg consumption has been an area of controversy regarding its impact on human health largely due to the content in cholesterol and its potential role in cardio-metabolic outcomes. This study aimed to summarise the level of evidence of egg consumption on various health outcomes. A systematic search for meta-analyses was performed: study design, dose-response relationship, heterogeneity and agreement of results over time, and identification of potential confounding factors were considered to assess the level of evidence. Results from this umbrella review showed a substantial no association between egg consumption and a number of health outcomes, including cancer, cardiovascular and metabolic …

DIABETIC DYSLIPIDEMIAEggsENDOTHELIAL FUNCTIONCANCER-RISKBLADDER-CANCERmeta-analysiPOOLED ANALYSISHuman healthMetabolic DiseasesRisk FactorsEnvironmental healthMedicineHumansBREAST-CANCEREggCORONARY-HEART-DISEASEEgg; cohort; evidence; meta-analysis; prospective; umbrella reviewSettore MED/49 - Scienze Tecniche Dietetiche ApplicateConsumption (economics)umbrella reviewbusiness.industryevidenceConfoundingEvidence-based medicinecohortprospectiveDietPROSTATE-CANCERmeta-analysisCardiovascular DiseasesCARDIOVASCULAR-DISEASEMeta-analysisCohortObservational studyDOSE-RESPONSE METAANALYSISDiet HealthybusinessFood ScienceSystematic search
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DIETARY HABITS, LIFE STYLES, FOOD CONSUMPTION

2006

DIETARY HABITS LIFE STYLES AND FOOD CONSUMPTION IN ADULT SUBJECTS ATTENDING GENERAL MEDICINE OUTPATIENT’S IN PALERMO
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La place de la viande dans le modèle alimentaire français

2008

The main objective of this article is to examine the consumption of meat in the French dietary pattern. In particular, we attempted to identify the current structure and evolution in the consumption of meat-based products, the sociological distribution of the meat-based consumption, and the culinary systems of food association/substitution in which it occurs. In this aim, we analyzed the individual data of consumption stemming from nutritional surveys performed by the CRÉDOC in 1999 and 2003, as well as the recent European data about the national indigenous consumption of meats. Both samples included 1,500 representative individuals of the French adult population (quota method) who reported…

DIETARY PATTERNS[SDV.AEN] Life Sciences [q-bio]/Food and NutritionMEATFOOD SURVEYCONSUMPTIONSOCIOLOGY[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
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Microenvironmental adaptation of experimental tumours to chronic vs acute hypoxia

2004

This study investigated long-term microenvironmental responses (oxygenation, perfusion, metabolic status, proliferation, vascular endothelial growth factor (VEGF) expression and vascularisation) to chronic hypoxia in experimental tumours. Experiments were performed using s.c.-implanted DS-sarcomas in rats. In order to induce more pronounced tumour hypoxia, one group of animals was housed in a hypoxic atmosphere (8% O(2)) for the whole period of tumour growth (chronic hypoxia). A second group was acutely exposed to inspiratory hypoxia for only 20 min prior to the measurements (acute hypoxia), whereas animals housed under normal atmospheric conditions served as controls. Acute hypoxia reduced…

DNA ReplicationMaleCancer ResearchPathologymedicine.medical_specialtyBiologyperfusionRats Sprague-Dawleychemistry.chemical_compoundOxygen ConsumptionVascularityIn vivomedicineAnimalsExperimental TherapeuticshypoxiaCell growthDNA NeoplasmNeoplasms ExperimentalOxygenationHypoxia (medical)VEGFCell HypoxiaRatsVascular endothelial growth factorDisease Models AnimalKineticscell proliferationBlood pressureOncologychemistryvascularityAcute DiseaseChronic Diseaseoxygenationmedicine.symptomPerfusionCell DivisionBritish Journal of Cancer
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Differences between cysteine and homocysteine in the induction of deoxyribose degradation and DNA damage.

2001

The effect of two naturally occurring thiols, such as cysteine and homocysteine, has been examined for their ability to induce deoxyribose degradation and DNA damage. Copper(II) ions have been added to incubation mixtures and oxygen consumption measurements have been performed in order to correlate the observed damaging effects with the rate of metal catalyzed thiol oxidation. Ascorbic acid plus copper has been used as a positive control of deoxyribose and DNA oxidation due to reactive oxygen species. Cysteine or homocysteine in the presence of copper ions induce the degradation of deoxyribose and the yield of 8-hydroxy-2'-deoxyguanosine (8-OHdG), although important differences are observed…

DNA damageAscorbic AcidThymus GlandBiochemistrySuperoxide dismutasechemistry.chemical_compoundOxygen ConsumptionPhysiology (medical)DeoxyguanosineAnimalsCysteineHomocysteineElectrophoresis Agar GelbiologyDeoxyriboseSuperoxide DismutaseThiourea8-Hydroxy-2'-deoxyguanosineDeoxyguanosineDNA oxidationAscorbic acidCatalasechemistryDeoxyriboseBiochemistry8-Hydroxy-2'-DeoxyguanosineSpectrophotometrybiology.proteinCattleReactive Oxygen SpeciesOxidation-ReductionCopperCysteineDNA DamageFree radical biologymedicine
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Divergent Distribution in Vascular and Avascular Mammalian Retinae Links Neuroglobin to Cellular Respiration

2005

The visual function of the vertebrate retina relies on sufficient supply with oxygen. Neuroglobin is a respiratory protein thought to play an essential role in oxygen homeostasis of neuronal cells. For further understanding of its function, we compared the distribution of neuroglobin and mitochondria in both vascular and avascular mammalian retinae. In the vascular retinae of mouse and rat, oxygen is supplied by the outer choroidal, deep retinal, and inner capillaries. We show that in this type of retina, mitochondria are concentrated in the inner segments of photoreceptor cells, the outer and the inner plexiform layers, and the ganglion cell layer. These are the same regions in which oxyge…

DNA Complementarygenetic structuresGuinea PigsMolecular Sequence DataRespiratory chainNeuroglobinNerve Tissue ProteinsMitochondrionBiologyBiochemistryRetinaMicechemistry.chemical_compoundOxygen ConsumptionOxygen homeostasismedicineAnimalsPhotoreceptor CellsTissue DistributionAmino Acid SequenceCloning MolecularMolecular BiologyGanglion cell layerMice Inbred BALB CRetinaChoroidAntibodies MonoclonalCytochromes cRetinal VesselsRetinalCell BiologyAnatomyImmunohistochemistryeye diseasesCapillariesGlobinsMitochondriaRatsCell biologyRespiratory proteinmedicine.anatomical_structurechemistryNeuroglobinsense organsSequence AlignmentJournal of Biological Chemistry
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The Xícaras from Don Hilarion: the public spaces and private homes in the eighteenth century rural

2012

El inventario post mortem y el libro de cuenta y razón del escribano Hilarión Cardona nos proporcionan una abundante información sobre las formas de vida y las actividades de este singular personaje y de su entorno. A su ascenso económico y social ayudará una estudiada política matrimonial, lo que le permitirá hacerse un hueco destacado entre los miembros de la oligarquía local. Lo nutrido y excepcional de su vestuario, junto con la posesión de novedosos objetos, nada comunes al resto de los inventarios de bienes, nos ofrecen una clara imagen del proceso de trasferencia de las formas de vida entre la ciudad y el medio rural. Hilarión sintetiza la emulación de los hábitos de comportamiento d…

DP1-402SuntuosidadConsumptionReligious studiesSociabilityHistory of SpainAscenso socialPossession (law)OligarchyHistoria ModernaModern history 1453-GeographySumptuousD204-475Capital (economics)EliteIndumentariaRuralRural areaSociabilidadConsumoHumanitiesCartographyMedio ruralSocial ascent clothing
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