Search results for "cop"

showing 10 items of 25502 documents

Semi densi, semi sottili. Infertilità e Harmoniae Veneris (a proposito di Lucr. IV, 1240-1277)

2010

Indagine sui principi di riproduzione considerati da Lucrezio e sulle forme di accoppiamento, soprattutto in rapporto alla fecondazione umana.

semiLucrezioaccoppiamentoSettore L-FIL-LET/04 - Lingua E Letteratura Latina
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Bcl-xL as a Modulator of Senescence and Aging

2021

Many features of aging result from the incapacity of cells to adapt to stress conditions. When cells are overwhelmed by stress, they can undergo senescence to avoid unrestricted growth of damaged cells. Recent findings have proven that cellular senescence is more than that. A specific grade of senescence promotes embryo development, tissue remodeling and wound healing. However, constant stresses and a weakening immune system can lead to senescence chronicity with aging. The accumulation of senescent cells is directly related to tissue dysfunction and age-related pathologies. Centenarians, the most aged individuals, should accumulate senescent cells and suffer from their deleterious effects,…

senescenceReviewmedicine.disease_causelcsh:Chemistry0302 clinical medicineImmunologic Surveillancelcsh:QH301-705.5SpectroscopyCellular Senescenceimmunosenescence0303 health sciencesapoptosisGeneral MedicineImmunosenescenceComputer Science ApplicationsCell biologyOrgan Specificity030220 oncology & carcinogenesisDisease SusceptibilitycentenariansProtein BindingSignal TransductionSenescencebcl-X ProteinBcl-xLBiologyCatalysisInorganic Chemistry03 medical and health sciencesImmune systemStress PhysiologicalmedicineAnimalsHumansPhysical and Theoretical ChemistrySenolyticMolecular Biology030304 developmental biologyBcl-xLOrganic ChemistryIntrinsic apoptosisagingGene Expression Regulationlcsh:Biology (General)lcsh:QD1-999senolyticsbiology.proteinWound healingOxidative stressBiomarkersDNA DamageInternational Journal of Molecular Sciences
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Serenoa repens, lycopene and selenium versus tamsulosin for the treatment of LUTS/BPH. An Italian multicenter double-blinded randomized study between…

2014

serenoa repensMaleProstatic HyperplasiaAntioxidantsSettore MED/24 - UrologiaSeleniumDouble-Blind MethodDrug TherapyLower Urinary Tract SymptomsSerenoa80 and overHumansBPH; LUTS; lycopene; phytotherapy; selenium; serenoa repens; tamsulosin; Aged; Aged 80 and over; Antioxidants; Carotenoids; Double-Blind Method; Drug Therapy Combination; Humans; Italy; Lower Urinary Tract Symptoms; Male; Middle Aged; Phytotherapy; Prostatic Hyperplasia; Quality of Life; Selenium; Serenoa; Sulfonamides; Treatment Outcome; Urodynamics; Urological AgentsAgedSulfonamidesLUTSphytotherapyMiddle AgedlycopeneCarotenoidsBPH LUTS lycopene phytotherapy selenium serenoa repens tamsulosinUrodynamicsTreatment OutcomeItalyBPHtamsulosinCombinationQuality of LifeUrological Agentsserenoa repens; lycopene; selenium; tamsulosin; LUTS; BPH; phytotherapy
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Tabanque : revista pedagógica

2008

A partir de la ley orgánica de ordenación general del sistema educativo (logse, 1990), los equipos de orientación escolar y psicopedagógica y los departamentos de orientación se constituyen como apoyos a un sistema único de enseñanza que atiende al conjunto de los alumnos, y adoptan funciones referidas a la atención a la diversidad.La atención a la diversidad hace referencia al conjunto de medidas generales y específicas para atender a todos los alumnos del centro. Los equipos de orientación escolar y psicopedagógica y los departamentos de orientación participan fundamentalmente en la aplicación de las medidas específicas de atención a la diversidad, pero también en las de carácter general.…

servicio de orientaciónorientación pedagógicaIntegración escolarLey Orgánica 1/1990 de Ordenación General del Sistema Educativo (LOGSE)PedagogíaEquipo de Asesoramiento Psicopedagógico (EAP)Pedagogialegislación educativa
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Reply to: Kow CS et al. Are severe asthma patients at higher risk of developing severe outcomes from COVID-19?

2021

severe asthma2019-20 coronavirus outbreakmedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Severe asthmaImmunologyComorbiditySettore MED/10 - Malattie Dell'Apparato RespiratorioCOVID-19 severe asthma COPDNOHumans; SARS-CoV-2; Asthma; COVID-19Internal medicineCorrespondencemedicineCOPDImmunology and AllergyHumansAsthmaCOVIDbusiness.industrySARS-CoV-2COVID-19asthmamedicine.diseaseItalybusiness
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Kin selection in interactions between gametes: Gamete competition, gamete limitation, and sex allocation

2023

Kin selection on one hand, and gamete interactions in post-ejaculatory sexual selection on the other are two major research themes that have risen to prominence over the past half century and have simultaneously developed into central fields of research in evolutionary biology. There is a natural connection between the two: when gametes interact with each other, very commonly many of them originate from the same parent and are thus siblings. For example, sperm competition will almost always involve competition between sibling gametes even if the interacting parents are not related to each other. If parents are related to each other, the relatedness between gametes increases further. Here we…

sex allocationrelatednesssiittiötsperm competition and limitationpost-copulatory sexual selectionevoluutiobiologiaEcologykin selectionsimultaneous hermaphroditesEcology Evolution Behavior and SystematicssukusolutFrontiers in Ecology and Evolution
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Development of New Targeted Inulin Complex Nanoaggregates for siRNA Delivery in Antitumor Therapy.

2021

Here, a novel strategy of formulating efficient polymeric carriers based on the already described INU-IMI-DETA for gene material whose structural, functional, and biological properties can be modulated and improved was successfully investigated. In particular, two novel derivatives of INU-IMI-DETA graft copolymer were synthesized by chemical functionalisation with epidermal growth factor (EGF) or polyethylenglycol (PEG), named INU-IMI-DETA-EGF and INU-IMI-DETA-PEG, respectively, in order to improve the performance of already described “inulin complex nanoaggregates” (ICONs). The latter were thus prepared by appropriately mixing the two copolymers, by varying each component from 0 to 100 wt%…

siRNA deliveryRNase PCellPharmaceutical Science02 engineering and technology010402 general chemistry01 natural sciencesArticleAnalytical Chemistrylcsh:QD241-441EGF; inulin; PEG; siRNA delivery; targeting; tumourlcsh:Organic chemistryEpidermal growth factorNeoplasmsDrug DiscoveryPEG ratioZeta potentialmedicineCopolymerHumansDoxorubicinPhysical and Theoretical ChemistryRNA Small InterferingtargetingEGFDrug CarriersinulinChemistrytumourOrganic ChemistryTransfection021001 nanoscience & nanotechnologyPEG0104 chemical sciencesNanostructuresmedicine.anatomical_structureSettore CHIM/09 - Farmaceutico Tecnologico ApplicativoChemistry (miscellaneous)BiophysicsMCF-7 CellsMolecular Medicine0210 nano-technologymedicine.drugMolecules (Basel, Switzerland)
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Structural properties of core and surface of silica nanoparticles investigated by Raman spectroscopy

2013

We studied the experimental Raman spectra of various commercial silica nanoparticles of average diameter from 7 to 40 nm and specific surface from 50 to 380 m^2/g. We found that the peculiarities of the particles Raman spectra systematically depend on their specific surface. In detail, the peak position of the R band at about 440 cm ^-1 shifts towards high wavenumbers following an almost linear dependence on the specific surface. Similarly, the amplitudes of the D1 and D2 bands, at about 495 and 605 cm ^-1, respectively, increase linearly with the same quantity. Our results are interpreted in the frame of the shell model for the nanoparticles clarifying that the network of the core of the n…

silica nanoparticleRaman spectroscopystructure
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Thioflavin-T doped silica nanoparticles by basic-catalyzed sol-gel synthesis

2014

We developed a basic-catalyzed sol-gel procedure that allows to synthesize silica nanoparticles functionalized with Thioflavin-T (ThT). During the synthesis, the formation of the doped silica nanoparticles was monitored by absorbance spectra indicating that the catalyst does not cause the total hydroxylation of the dye. Fluorescence measurements carried out on the ThT doped silica nanoparticles proved the attachment of ThT on silica and Raman spectroscopy provided information about the dye structure.

silica nanoparticleRaman spectroscopy.sol-gelThioflavin-Tdye-doping
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Resonance Raman of oxygen dangling bonds in amorphous silicon dioxide

2017

We investigate the origin of a resonance Raman band induced by ionizing radiation in amorphous silicon dioxide (silica glass), which can be detected under ultraviolet laser excitation. A silica sample, rich of oxygen-excess related defects, was prepared by treating some length of a pure-silica-core multimode fiber in an O2 atmosphere (at high temperature and pressure) and by irradiating it with X-rays at 10 MGy(SiO2) dose. A micro-Raman study revealed a gaussian band peaking at 896 cm−1 with a full width at half maximum of 32 cm−1, which could be detected by exciting the sample with the 325-nm line of a HeCd laser. This spectral feature is absent in the Raman spectra performed with the 442-…

silicapoint defectSettore FIS/01 - Fisica Sperimentalenon-bridging oxygenMaterials Science (all)Spectroscopyresonance Raman
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