Search results for "corn"

showing 10 items of 710 documents

Heritability of corneal refraction and corneal astigmatism: a population-based twin study among 66- to 79-year-old female twins.

2012

. Purpose:  To examine the heritability of corneal refraction power (CR) and corneal astigmatism (AST) in older women. Methods:  Corneal refraction and AST were measured by IOL master in 52 monozygotic (MZ) and 47 dizygotic (DZ) female twin pairs aged 66–79 years. The relative contribution of genetic and environmental factors to individual differences in CR was estimated by applying an independent pathway model to the twin data and AST by intraclass correlations (ICC). Results:  For the right eye, mean CR was 44.58 dioptres (D) (standard deviation (SD) ±1.28) When comparing CR of the right and left eye between MZ and DZ, no significant difference was found. Mean AST was 0.77 D (SD ±0.44) wi…

medicine.medical_specialtyInheritance PatternsPopulation basedAstigmatismRefraction OcularWhite People03 medical and health sciences0302 clinical medicineCorneaOphthalmologyDiseases in TwinsTwins DizygoticMedicineHumansFinland030304 developmental biologyAgedGenetics0303 health sciencesModels Geneticbusiness.industrySignificant differenceAstigmatismGeneral MedicineTwins MonozygoticHeritabilitymedicine.diseaseTwin studyConfidence intervalOphthalmologymedicine.anatomical_structure030221 ophthalmology & optometryFemaleGene-Environment InteractionbusinessCorneal astigmatismActa ophthalmologica
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Reliability of iCare ic100 Rebound Tonometry and Agreement With Goldmann Applanation Tonometry in Healthy and Post-myopic LASIK Patients.

2021

Rebound tonometry offers excellent reliability for obtaining intraocular pressure (IOP) measurements in healthy and post-myopic laser-assisted in situ keratomileusis (LASIK) patients regardless of corneal parameters and axial length and regardless of the instillation of ocular topical anesthesia.The purpose of this study was to assess the reliability of rebound tonometry, its agreement with Goldmann applanation tonometry (GAT) and its concordance after topical anesthesia in a group of nonoperated healthy patients and a group of post-myopic LASIK patients.Fifty-four patients were included in this prospective observational, case-control study. Patients were divided into 2 groups: control (n=3…

medicine.medical_specialtyIntraocular pressuregenetic structuresIntraclass correlationManometrymedicine.medical_treatmentConcordanceKeratomileusis Laser In SituGlaucomaKeratomileusisCorneaTonometry OcularOphthalmologymedicineHumansIntraocular PressureReproducibilitybusiness.industryLASIKReproducibility of ResultsRepeatabilitymedicine.diseaseeye diseasesOphthalmologyCase-Control Studiessense organsbusinessJournal of glaucoma
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Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus

2013

The author manuscript of this article is open access and is freely available online at PubMed Central

medicine.medical_specialtyKeratoconusCorneal Pachymetrygenetic structuresthickness; keratoconus; geneGlaucomaOcular hypertensionGenome-wide association studyBiologyReal-Time Polymerase Chain ReactionKeratoconusWhite PeopleArticleCentral corneal thicknessCorneaAsian PeopleOphthalmologyCorneaOdds RatioGeneticsmedicineHumansCorneal pachymetrymedicine.diagnostic_testForkhead Box Protein O1Forkhead Transcription FactorsGlaucomaOdds ratioMicroarray Analysismedicine.diseaseConfidence intervaleye diseasesFibronectinsmedicine.anatomical_structureGenetic Locisense organsGenome-Wide Association Study
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Implantation of a custom intraocular lens with a 30-diopter torus for the correction of high astigmatism after penetrating keratoplasty.

2003

Abstract We present a 62-year-old woman who had implantation of an intraocular lens (IOL) with a torus of 30.0 diopters (D) in an eye after penetrating keratoplasty. The patient presented with cataract and a best corrected visual acuity of 20/400. Penetrating keratoplasty was performed in 1975 because of decompensated keratoconus. With a clear but inferiorly decentered corneal graft, visual acuity was limited because of keratoplasty-related high corneal astigmatism of 22.5@156 that could not be successfully treated with spectacles or contact lenses. A custom toric IOL with –30.0 D of cylindrical power was implanted in the capsular bag via a sclerocorneal tunnel incision. Additionally, a sph…

medicine.medical_specialtyKeratoconusRefractive errorVisual acuitygenetic structuresmedicine.medical_treatmentEye diseaseVisual AcuityIntraocular lensAstigmatismKeratoconusProsthesis DesignCataractHigh astigmatismLens Implantation IntraocularOphthalmologymedicineHumansDioptreLenses IntraocularPhacoemulsificationbusiness.industryAstigmatismCorneal TopographyMiddle Agedmedicine.diseaseeye diseasesSensory SystemsOphthalmologyOptometrySurgeryFemalesense organsmedicine.symptombusinessKeratoplasty PenetratingJournal of cataract and refractive surgery
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Fulminant bilateral Haemophilus influenzae keratitis in a patient with hypovitaminosis A treated with contaminated autologous serum

2011

We report on a patient with hypovitaminosis A treated with autologous serum (AS) who had bilateral infectious ulcers positive for Haemophilus influenzae. The patient suffered a perforation of his right eye and total healing of his left eye with a residual leukoma. In cases of severe malnutrition, serum levels of vitamins and bacteriostatic and growth factors are reduced, so AS would not only be ineffective but also increase the risk of secondary corneal infection. The prophylactic use of a topical antibiotic would be useful in treatment with AS, especially in patients who do not use and adequately store the eye drops, as in our patient.

medicine.medical_specialtyLeukomaCorneal Infectionbiologygenetic structuresbusiness.industryFulminantPerforation (oil well)Hypovitaminosis ACase Reportmedicine.diseasemedicine.disease_causeAutologous serumbiology.organism_classificationHaemophilus influenzaeeye diseasesSurgeryHaemophilus influenzaeKeratitisOphthalmologymedicinehypovitaminosis Abilateral infectious ulcerssense organsbusinessClinical Ophthalmology (Auckland, N.Z.)
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Application principles of excimer lasers in ophthalmology

2010

Abstract Excimer lasers (193 nm) can be used for photoablation of the human cornea due to their specific physical characteristics. This laser is applied in corneal refractive surgery for the targeted removal of corneal tissue for the purpose of correcting refractive errors. This article provides a short overview of the scientific development of excimer lasers for use in ophthalmic surgery and of the range of applications of these tools.

medicine.medical_specialtyMaterials sciencebusiness.industrymedicine.medical_treatmentPhotoablationDermatologyExcimerLasereye diseaseslaw.inventionOpticsmedicine.anatomical_structureCorneal edemaScientific developmentlawOphthalmologyCorneaRefractive surgerymedicineOptoelectronicsSurgerysense organsbusinessOphthalmic surgeryMedical Laser Application
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Irregularity of the posterior corneal surface during applanation using a curved femtosecond laser interface and microkeratome cutting head.

2012

PURPOSE: To evaluate the irregularity of the posterior corneal surface and intrastromal dissection during the preparation of donor tissue for Descemet stripping automated endothelial keratoplasty (DSAEK) using a curved interface femtosecond laser and microkeratome. METHODS: Sixteen human donor corneas unsuitable for transplantation were divided into two groups: a femtosecond (FS) laser group (n=7) using the VisuMax femtosecond laser (Carl Zeiss Meditec) and a microkeratome group (n=9) using the Amadeus II microkeratome (Ziemer Ophthalmic Group). The corneas were fixed on artificial anterior chambers. Horizontal cross-sections were obtained using spectral-domain optical coherence tomography…

medicine.medical_specialtyMaterials sciencegenetic structuresSurface PropertiesCorneal Stromalaw.inventionOpticsOptical coherence tomographylawMicrokeratomeOphthalmologyCorneamedicineHumansCorneal surfaceAged 80 and overmedicine.diagnostic_testbusiness.industryEndothelium CornealDescemet stripping automated endothelial keratoplastyLasereye diseasesTissue DonorsTransplantationOphthalmologymedicine.anatomical_structureFemtosecondSurgeryLasers Excimersense organsbusinessDescemet Stripping Endothelial KeratoplastyTomography Optical CoherenceJournal of refractive surgery (Thorofare, N.J. : 1995)
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2015

Ocular signs in Fabry disease have generally been regarded to be primarily of diagnostic value. We explored whether ocular findings, alone or in particular in combination with the α-galactosidase A gene mutation, have predictive value for disease severity. Data from the Fabry Outcome Survey (FOS), a large, global database sponsored by Shire, were selected for adult patients who had undergone ophthalmological examination. Three ocular signs were assessed: cornea verticillata, tortuous conjunctival and/or retinal vessels, and cataract. Fabry disease severity was measured using FOS Mainz Severity Score Index and modifications thereof. Ophthalmological data were available for 1203 (699 female, …

medicine.medical_specialtyMultidisciplinarybusiness.industryAge adjustmentmedicine.diseaseFabry diseaseeye diseasesmedicine.anatomical_structureCataractsOphthalmologyInternal medicineCorneaGenotypemedicineMissense mutationCornea verticillatasense organsEye Findingmedicine.symptombusinessPLOS ONE
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Reduced corneal thickness values in postmenopausal women with dry eye.

2004

To study and compare the corneal thickness values of postmenopausal women with dry eye and postmenopausal women without dry eye.The corneal thickness value of 30 postmenopausal women with dry eye (dry eye group; aged 52 to 55 years) and 32 postmenopausal women without dry eye (normal group; aged 51 to 55 years) was analyzed with the Orbscan Topography System II. Each woman underwent a tear breakup test, the Schirmer test, fluorescein staining of the cornea, and an analysis of the meibomian gland by slit lamp before corneal thickness measurement. The statistical analysis was performed by means of the unpaired Student t test.The mean corneal thickness value was significantly decreased in post…

medicine.medical_specialtyPostmenopausal womengenetic structuresbusiness.industryCorneal TopographyMeibomian GlandsMiddle Agedeye diseasesSurgeryCorneaPostmenopauseOphthalmologyOphthalmologyTearsMedicineHumansBody Weights and MeasuresDry Eye SyndromesFemalesense organsProspective StudiesbusinessCornea
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Changes in higher-order aberrations after implantation of a foldable iris-claw lens in myopic phakic eyes

2006

Purpose To evaluate the change in higher-order aberrations (HOAs) after implantation of a foldable iris-claw phakic intraocular lens (pIOL) in myopic eyes. Setting Department of Ophthalmology, Johannes Gutenberg-University, Mainz, Germany. Methods This prospective nonrandomized comparative self-controlled trial included 41 eyes that had implantation of a foldable iris-claw pIOL between July 2003 and November 2004. All patient data for HOAs (Zernike coefficient) were measured and calculated using the same pupil size preoperatively and postoperatively, and the root-mean-square (RMS) wavefront error was calculated. Examinations were performed preoperatively as well as 1 week and 3, 6, and 12 m…

medicine.medical_specialtyRefractive errorgenetic structuresAnterior ChamberEye diseaseVisual AcuityIrisPhakic intraocular lensCorneaVision disorderLens Implantation IntraocularOphthalmologyLens CrystallineMyopiaHumansMedicineProspective StudiesIris clawDioptreLenses Intraocularbusiness.industryRefractive Errorsmedicine.diseaseeye diseasesSensory SystemsOphthalmologyAberrations of the eyemedicine.anatomical_structureLens (anatomy)Silicone ElastomersSurgerysense organsmedicine.symptombusinessJournal of Cataract and Refractive Surgery
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