Search results for "corona"

showing 10 items of 3472 documents

Impact of smoking on COVID-19 outcomes: a HOPE Registry subanalysis

2021

BackgroundSmoking has been associated with poorer outcomes in relation to COVID-19. Smokers have higher risk of mortality and have a more severe clinical course. There is paucity of data available on this issue, and a definitive link between smoking and COVID-19 prognosis has yet to be established.MethodsWe included 5224 patients with COVID-19 with an available smoking history in a multicentre international registry Health Outcome Predictive Evaluation for COVID-19 (NCT04334291). Patients were included following an in-hospital admission with a COVID-19 diagnosis. We analysed the outcomes of patients with a current or prior history of smoking compared with the non-smoking group. The primary …

2474medicine.medical_specialtyRC620-627Health (social science)Coronavirus disease 2019 (COVID-19)infectious diseaseMedicine (miscellaneous)Health outcomesSepsis03 medical and health sciences0302 clinical medicineInternal medicinemedicineClinical endpointRisk of mortality1506030212 general & internal medicineNutritional diseases. Deficiency diseasesOriginal Researchpulmonary diseaseNutrition and Dieteticsbusiness.industry2524Clinical courseCOVID-19medicine.diseaseFormer Smoker030228 respiratory systemSmoking statusbusinessBMJ Nutrition, Prevention & Health
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Quality Control in 3D Printing: Accuracy Analysis of 3D-Printed Models of Patient-Specific Anatomy

2021

As comparative data on the precision of 3D-printed anatomical models are sparse, the aim of this study was to evaluate the accuracy of 3D-printed models of vascular anatomy generated by two commonly used printing technologies. Thirty-five 3D models of large (aortic, wall thickness of 2 mm, n = 30) and small (coronary, wall thickness of 1.25 mm, n = 5) vessels printed with fused deposition modeling (FDM) (rigid, n = 20) and PolyJet (flexible, n = 15) technology were subjected to high-resolution CT scans. From the resulting DICOM (Digital Imaging and Communications in Medicine) dataset, an STL file was generated and wall thickness as well as surface congruency were compared with the original …

3d printedMaterials science3D printing3d modelFDM printing030204 cardiovascular system & hematologylcsh:TechnologyArticle030218 nuclear medicine & medical imaginglaw.invention03 medical and health sciencesDICOM3D engineering0302 clinical medicinelawStl fileGeneral Materials Sciencelcsh:Microscopycoronarylcsh:QC120-168.85anatomical modellcsh:QH201-278.5Fused deposition modelingaccuracyPolyJet printinglcsh:Tbusiness.industryAnatomy3D printingPatient specificaortalcsh:TA1-2040lcsh:Descriptive and experimental mechanicslcsh:Electrical engineering. Electronics. Nuclear engineeringlcsh:Engineering (General). Civil engineering (General)Wall thicknessbusinesslcsh:TK1-9971Materials
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Polymeric Nanoparticles with Neglectable Protein Corona

2020

Small : nano micro 16(18), 1907574 (2020). doi:10.1002/smll.201907574

540 Chemistry and allied sciencesDispersity610 Medizinmicellar structuresNanoparticleProtein Corona02 engineering and technology010402 general chemistry01 natural sciencesPolyethylene GlycolsBiomaterialschemistry.chemical_compoundAdsorption610 Medical sciencesHumansGeneral Materials ScienceParticle SizeGel electrophoresisChemistryasymmetrical flow field-flow fractionationSarcosineGeneral Chemistry021001 nanoscience & nanotechnology0104 chemical sciencesChemical engineering540 Chemiedrug deliveryNanoparticlesParticleProtein CoronaParticle sizePeptides0210 nano-technologyHydrophobic and Hydrophilic InteractionsEthylene glycolBiotechnologySmall
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Nanoparticles in the Biological Context: Surface Morphology and Protein Corona Formation

2020

Small 16(39), 2002162 (2020). doi:10.1002/smll.202002162

540 Chemistry and allied sciencesMaterials scienceMorphology (linguistics)Shell (structure)NanoparticleContext (language use)Protein Corona02 engineering and technology010402 general chemistry01 natural sciencesMass SpectrometryBiomaterialsColloidCorona (optical phenomenon)General Materials ScienceBackground subtractionBlood ProteinsGeneral Chemistry021001 nanoscience & nanotechnology5400104 chemical sciencesChemical physics540 Chemieddc:540NanoparticlesProtein Corona0210 nano-technologyBiotechnology
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La presencia de la ciencia en las bibliotecas de la corona de Aragón en el siglo XVI

2002

Tesis doctoral del Departamento de Historia de la Ciencia y Documentación de la Universitat de València (UV).-- Fecha de defensa: 11/09/2002.

61MedicinaHistoria de la cienciaCorona de AragónInventarios de bibliotecasSiglo XVI
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A Phase I/II Dose-Escalation Multi-Center Study to Evaluate the Safety of Infusion of Natural Killer Cells or Memory T Cells As Adoptive Therapy in C…

2021

Abstract Background: Adoptive cell immunotherapies for opportunistic virus in immunocompromised patients using haploidentical memory T cells have shown to be safe and effective. Since severe cases of COVID-19 present a dysregulated immune system with T cell lymphopenia and a hyper-inflammatory state we have proposed that a similar strategy could be proven to be efficient for COVID-19 patients. This is a study protocol of an open-label, multicenter, double-arm, randomized, dose-finding phase I/II clinical trial to evaluate the feasibility, safety, tolerability, and efficacy of the administration of a single dose of allogenic SARS-CoV-2 specific memory CD45RA - T cells and Natural Killer (NK)…

704.Cellular Immunotherapies: Clinicalbusiness.industryImmunologyCell BiologyHematologymedicine.disease_causemedicine.diseaseBiochemistryPneumoniaPhase i iiMulti center studyImmunologymedicineDose escalationbusinessCoronavirusBlood
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La multidimensionalidad de una pandemia. Sociedad y Derecho en la era del post-coronavirus

2020

La multidimensionalidad de lecturas que se han abierto derivadas de los efectos del Covid-19 (filosófica, sociológica y jurídica) ofrece una oportunidad para reflexionar sobre algunas dicotomías –además de la ya clásica salud/economía- tales como riesgo-miedo/alteridad, individualismo/comunidad, así como a revisar algunos de los relatos y narrativas que han intentado explicar lo que esta crisis ha supuesto y el escenario post-pandémico que podría configurarse. A partir del análisis de las dimensiones filosófica y sociológica, se pretende sentar las bases para identificar qué cuestiones nucleares inciden en la dimensión jurídica y, a partir de ahí, apuntar algunos parámetros acerca de cómo p…

:CIENCIAS JURÍDICAS [UNESCO]PhilosophyIndividualismDichotomyCoronavirus disease 2019 (COVID-19)UNESCO::CIENCIAS JURÍDICASAlterityNarrativeSociologyLawHumanities
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Delineamientos de desarrollo local en tiempos de incertidumbre: oportunidad para otro tipo de planteamientos / / / \ \ \ Local development outlines i…

2020

Resumen: La pandemia de Covid-19 han impactado en todos los ámbitos sociales y aspectos comunitarios, sociales y subjetivos. En el desarrollo local y regional esta situación ha tenido unos efectos devastadores sobre los que todavía es temprano para evaluar sus efectos, de tal manera que es posible referirse a un “antes” y un “después”. En este escenario y contexto inédito de incertezas y riesgos, es posible referirse a la contingencia como un nuevo marco de descripción de las sociedades, en la que los conceptos teóricos del desarrollo local (y social en general) deberán explorar nuevos conceptos emergentes, como son, el riesgo y el peligro, y con ello, repensar la lógica y teorías del desar…

:GEOGRAFÍA [UNESCO]Coronavirus disease 2019 (COVID-19)Regional developmentWelfare economicsSocial changeLocal DevelopmentContext (language use)SociologyUNESCO::GEOGRAFÍATERRA: Revista de Desarrollo Local
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Ámbito de relación entre el poder real y los municipios de la Corona de Aragón durante la época foral moderna

2006

La gobernación efectiva de los territorios que integraban la monarquía hispánica descansaba en gran medida en la operatividad de las diversas vías de comunicación establecidas entre el centro y la periferia. En este contexto temático, se tratará de esbozar aquí un breve recorrido por los distintos cauces a través de los cuales se desenvolvían las relaciones entre la administración real y la municipal, en el ámbito de la Corona de Aragón durante la época de los Austrias. Más allá de las diferencias y peculiaridades propias de cada reino, se ha primado un enfoque que, a partir de las similitudes institucionales, trate de dar cuenta de los rasgos que caracterizaban los diversos marcos de relac…

:HISTORIA::Historia moderna [UNESCO]MunicipioHumanidadesMunicipalityOficiales realesUNESCO::HISTORIA::Historia modernaCorona de AragónAustriasCrown of AragonRoyal officialsHistoria
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Recomendaciones en el manejo de la pandemia por coronavirus SARS-CoV-2 (Covid-19) en pacientes con trasplante renal

2020

The SARS-CoV-2 (Covid-19) coronavirus pandemic is evolving very quickly and means a special risk for both immunosuppressed and comorbid patients. Knowledge about this growing infection is also increasing although many uncertainties remain, especially in the kidney transplant population. This manuscript presents a proposal for action with general and specific recommendations to protect and prevent infection in this vulnerable population such as kidney transplant recipients. Resumen: La pandemia por coronavirus SARS-CoV-2 (Covid-19) está evolucionando de manera muy rápida y representa un riesgo especial en pacientes inmunodeprimidos y con comorbilidades añadidas. El conocimiento sobre esta in…

:Phenomena and Processes::Immune System Phenomena::Immunocompromised Host [Medical Subject Headings]:Anatomy::Urogenital System::Urinary Tract::Kidney [Medical Subject Headings]Coronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Population030230 surgerylcsh:RC870-923medicine.disease_causeKidney transplant:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors [Medical Subject Headings]:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Kidney transplantation03 medical and health sciences0302 clinical medicine:Health Care::Health Care Quality Access and Evaluation::Quality of Health Care::Epidemiologic Factors::Comorbidity [Medical Subject Headings]PandemicCOVID-19 ; inmunodeprimido ; trasplante renal ; kidney transplantation ; immunosuppressed ; SARS-CoV-2MedicineVulnerable population030212 general & internal medicineeducationKidney transplantationCoronavirus:Geographical Locations::Geographic Locations::Europe::Spain [Medical Subject Headings]education.field_of_studyInmunodeprimidoSARS-CoV-2business.industry:Health Care::Environment and Public Health::Public Health::Disease Outbreaks::Epidemics::Pandemics [Medical Subject Headings]lcsh:Diseases of the genitourinary system. Urologymedicine.diseaseVirology:Diseases::Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections [Medical Subject Headings]Trasplante renalImmunosuppressedNephrology:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Immunologic Factors::Immunosuppressive Agents [Medical Subject Headings]Covid-19businessNefrología (English Edition)
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