Search results for "correction"

showing 10 items of 601 documents

Sox-2 Positive Neural Progenitors in the Primate Striatum Undergo Dynamic Changes after Dopamine Denervation.

2013

The existence of endogenous neural progenitors in the nigrostriatal system could represent a powerful tool for restorative therapies in Parkinson's disease. Sox-2 is a transcription factor expressed in pluripotent and adult stem cells, including neural progenitors. In the adult brain Sox-2 is expressed in the neurogenic niches. There is also widespread expression of Sox-2 in other brain regions, although the neurogenic potential outside the niches is uncertain. Here, we analyzed the presence of Sox-2(+) cells in the adult primate (Macaca fascicularis) brain in naïve animals (N = 3) and in animals exposed to systemic administration of 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine to render th…

MalePathologyDopamineFluorescent Antibody Techniquelcsh:MedicineDopaminaStriatumchemistry.chemical_compoundNeural Stem CellsNeurobiology of Disease and RegenerationSox-2 PositiveNeurocièncieslcsh:Scienceeducation.field_of_studyMultidisciplinaryMPTPStem CellsCell DifferentiationNeurochemistryNeurodegenerative DiseasesParkinson DiseaseAnimal ModelsDopamine DenervationDenervationSubstantia NigraAdult Stem CellsNeurologyembryonic structuresMedicineNeural ProgenitorsCalretininNeurochemicalsMacaqueAdult stem cellmedicine.drugResearch Articlemedicine.medical_specialtyendocrine systemNeurogenesisPopulationSubstantia nigraModel OrganismsDevelopmental NeuroscienceDopamineInternal medicinemedicineAnimalsProgenitor celleducationBiologyurogenital systemSOXB1 Transcription Factorslcsh:RCorrectionCorpus StriatumMacaca fascicularisEndocrinologychemistrynervous systemlcsh:QDevelopmental BiologyNeurosciencePLoS ONE
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BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups.

2014

BRAF-V600E expression is identified in hematopoietic progenitor and precursor myeloid dendritic cells in patients with high-risk LCH, and enforced expression of BRAF-V600E in CD11c+ cells recapitulates a high-risk LCH-like phenotype in mice.

MalePathologyendocrine system diseasesCellular differentiationCD34Antigens CD34Mice0302 clinical medicineLangerhans cell histiocytosisBone MarrowRisk FactorsImmunology and Allergyskin and connective tissue diseasesChild0303 health sciencesCell Differentiation3. Good healthHistiocytosismedicine.anatomical_structurePhenotypeTreatment Outcome030220 oncology & carcinogenesisChild PreschoolAntigens Surface2723 Immunology and AllergyFemaleProto-Oncogene Proteins B-rafmedicine.medical_specialtyImmunologyCD11c610 Medicine & healthBiologyArticle03 medical and health sciencesGermline mutationmedicineAnimalsHumansCell LineageGenetic Predisposition to DiseaseLectins C-TypeProgenitor cellneoplasms030304 developmental biology2403 ImmunologyHistocompatibility Antigens Class II302InfantCorrectionDendritic Cellsmedicine.diseaseHematopoietic Stem Cellsdigestive system diseasesCD11c Antigenenzymes and coenzymes (carbohydrates)Histiocytosis Langerhans-CellMannose-Binding Lectins10032 Clinic for Oncology and HematologyMutationBone marrowThe Journal of experimental medicine
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Correction: Santa-Marina et al. Maternal Ferritin Levels during Pregnancy and ADHD Symptoms in 4-Year-Old Children: Results from the INMA-INfancia y …

2021

Ferritin status during prenatal brain development may influence the risk of attention deficit and hyperactivity disorder (ADHD) symptoms in childhood. We investigated the association of maternal ferritin in pregnancy and ADHD-like symptoms in offspring. A total of 1095 mother-child pairs from three birth cohorts of the INMA Project (Spain) were studied. Maternal plasma ferritin in pregnancy was measured at 11.57 weeks of gestation. Children's ADHD-like symptoms at ages 4-5 years were assessed using the ADHD Rating Scale-IV. The count model of the zero-inflated Poisson regression model showed a significant inverse association between ferritin (continuous variable) and inattention, β = -0.19 …

MalePediatricsmedicine.medical_specialtyHealth Toxicology and MutagenesisFerritin levels010501 environmental sciences01 natural sciencesCohort Studies03 medical and health sciencesSex Factors0302 clinical medicinePregnancymedicineHumansProspective Studies030212 general & internal medicineAdhd symptoms0105 earth and related environmental sciencesPregnancybusiness.industryPublic healthINTPublic Health Environmental and Occupational HealthRCorrectionmedicine.disease3. Good healthn/aAttention Deficit Disorder with HyperactivitySpainChild PreschoolPrenatal Exposure Delayed EffectsFerritinsRegression AnalysisMedicineFemalebusinessBirth cohortInternational Journal of Environmental Research and Public Health
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Physical and cognitive doping in university students using the unrelated question model (UQM): Assessing the influence of the probability of receivin…

2018

Study objectives: In order to increase the value of randomized response techniques (RRTs) as tools for studying sensitive issues, the present study investigated whether the prevalence estimate for a sensitive item π̂$_{s}$ assessed with the unrelated questionnaire method (UQM) is influenced by changing the probability of receiving the sensitive question p. Material and methods: A short paper-and-pencil questionnaire was distributed to 1.243 university students assessing the 12-month prevalence of physical and cognitive doping using two versions of the UQM with different probabilities for receiving the sensitive question (p ≈ 1/3 and p ≈ 2/3). Likelihood ratio tests were used to assess wheth…

MaleQuestionnairesPeptide Hormoneslcsh:MedicineSocial SciencesBiochemistryMathematical and Statistical Techniques0504 sociologySociologySurveys and QuestionnairesStatisticsPrevalenceMedicine and Health SciencesHuman Performanceddc:796lcsh:ScienceMathematicsDoping in SportsMultidisciplinarySocial ResearchOrganic Compounds05 social sciencesDrugsCognitionMiddle AgedChemistryAthletic & outdoor sports & gamesNeurologyResearch DesignBehavioral PharmacologyPhysical SciencesFemaleSteroidsResearch ArticleAdultAdolescentUniversitiesSubstance-Related DisordersStreet drugsBayesian MethodResearch and Analysis Methods050105 experimental psychologyYoung AdultNeuropharmacologySensitive questionRecreational Drug UseHumans0501 psychology and cognitive sciencesStudentsErythropoietinPharmacologyPsychotropic DrugsBehaviorModels StatisticalSurvey ResearchIllicit Drugslcsh:RAmphetaminesOrganic ChemistryChemical CompoundsCorrection050401 social sciences methodsBiology and Life SciencesHormonesSample size determinationlcsh:QPLoS ONE
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Long-term clinical and radiographic outcomes and patient satisfaction after adult spinal deformity correction

2018

Background and Aims: Adult spinal deformity surgery has increased with the aging population and modern surgical approaches, although it has high complication and reoperation rates. The permanence of radiographic correction, mechanical complications, predictive factors for poor patient-reported outcomes, and patient satisfaction were analyzed. Material and Methods: A total of 79 adult patients were retrospectively analyzed at baseline and 1–9 years after adult spinal deformity correction between 2007 and 2016. Patient-reported outcomes (Oswestry Disability Index, visual analog scale, and Scoliosis Research Society–30 scores), changes in radiographic alignment, indications for reoperation, pr…

MaleScoliosis Research Society-30medicine.medical_specialtypatient satisfactionSURGERYRadiographyMULTICENTERSpinal deformity correctionAdult spinal deformitycomplicationreoperationlong-term follow-upScoliosisSpinal CurvaturesPARAMETERSDisability Evaluation03 medical and health sciences0302 clinical medicinePatient satisfactionFUSIONmedicineHumansSCOLIOSISVALIDITYOswestry Disability IndexRetrospective Studiessagittal alignmentSurgical approachbusiness.industrySTIFFNESSMiddle Agedmedicine.disease3126 Surgery anesthesiology intensive care radiology3. Good healthSurgeryOswestry Disability Index030220 oncology & carcinogenesisBALANCERELIABILITYSpinal deformityoutcomeFemale030211 gastroenterology & hepatologybusinessComplication
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β blockers and mortality after myocardial infarction in patients without heart failure: multicentre prospective cohort study.

2016

OBJECTIVE To assess the association between early and prolonged beta blocker treatment and mortality after acute myocardial infarction. DESIGN Multicentre prospective cohort study. SETTING Nationwide French registry of Acute ST- and non-STelevation Myocardial Infarction (FAST-MI) (at 223 centres) at the end of 2005. PARTICIPANTS 2679 consecutive patients with acute myocardial infarction and without heart failure or left ventricular dysfunction. MAIN OUTCOME MEASURES Mortality was assessed at 30 days in relation to early use of beta blockers (<= 48 hours of admission), at one year in relation to discharge prescription, and at five years in relation to one year use. RESULTS beta blockers were…

MaleTime FactorsMyocardial Infarction030204 cardiovascular system & hematologyCorrectionsCohort Studies0302 clinical medicineMedicine030212 general & internal medicineMyocardial infarctionProspective StudiesProspective cohort studyHazard ratioGeneral MedicineMiddle AgedMetaanalysisPatient Discharge3. Good healthManagementImpactAcute DiseaseCardiologyFemaleLife Sciences & Biomedicinemedicine.medical_specialtyRegistrySt-Segment-Elevationmedicine.drug_classAdrenergic beta-AntagonistsGuidelines03 medical and health sciencesMedicine General & InternalFast-MiInternal medicineGeneral & Internal Medicine[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathologyClinical-OutcomesHumansBeta blockerSurvival analysisAgedProportional Hazards ModelsHeart FailureScience & Technologybusiness.industryProportional hazards modelResearchCoronary Care Unitsmedicine.diseaseSurvival AnalysisDiscontinuationLogistic ModelsAdherenceHeart failureTherapybusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyBMJ (Clinical research ed.)
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TMS-evoked long-lasting artefacts: A new adaptive algorithm for EEG signal correction

2017

Abstract Objective During EEG the discharge of TMS generates a long-lasting decay artefact (DA) that makes the analysis of TMS-evoked potentials (TEPs) difficult. Our aim was twofold: (1) to describe how the DA affects the recorded EEG and (2) to develop a new adaptive detrend algorithm (ADA) able to correct the DA. Methods We performed two experiments testing 50 healthy volunteers. In experiment 1, we tested the efficacy of ADA by comparing it with two commonly-used independent component analysis (ICA) algorithms. In experiment 2, we further investigated the efficiency of ADA and the impact of the DA evoked from TMS over frontal, motor and parietal areas. Results Our results demonstrated t…

MaleTime Factorsmedicine.medical_treatmentElectroencephalographySignal0302 clinical medicineSignal correctionDetrendEEGAdaptive algorithmmedicine.diagnostic_test05 social sciencesElectroencephalographyTranscranial Magnetic StimulationSensory SystemsAlgorithmNeurologyArtefact; Detrend; EEG; ICA; TMS; Sensory Systems; Neurology; Neurology (clinical); Physiology (medical)ArtifactFemalePrimary motor cortexArtifactsPsychologyAlgorithmsHumanAdultTime Factor050105 experimental psychologyNOYoung Adult03 medical and health sciencesPhysiology (medical)medicineHumansMiddle frontal gyrus0501 psychology and cognitive sciencesICAArtefactSettore M-PSI/02 - Psicobiologia E Psicologia Fisiologicabusiness.industryPattern recognitionIndependent component analysisTranscranial magnetic stimulationTMSNeurology (clinical)Artificial intelligenceSensory SystembusinessNeuroscience030217 neurology & neurosurgeryClinical Neurophysiology
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Cancer mortality inequalities in urban areas: a Bayesian small area analysis in Spanish cities

2011

incluye "Erratum to: Cancer mortality inequalities in urban areas: a Bayesian small area analysis in Spanish cities" BACKGROUND: Intra-urban inequalities in mortality have been infrequently analysed in European contexts. The aim of the present study was to analyse patterns of cancer mortality and their relationship with socioeconomic deprivation in small areas in 11 Spanish cities. METHODS: It is a cross-sectional ecological design using mortality data (years 1996-2003). Units of analysis were the census tracts. A deprivation index was calculated for each census tract. In order to control the variability in estimating the risk of dying we used Bayesian models. We present the RR of the censu…

MaleUrban PopulationEstudios transversalesCross-sectional studyEspaña:Health Care::Environment and Public Health::Public Health::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cross-Sectional Studies [Medical Subject Headings]Business Management and Accounting(all)Disparidades en el estado de saludPoblación urbanaHealth informatics:Health Care::Population Characteristics::Population::Urban Population [Medical Subject Headings]NeoplasmsHuman geographyEpidemiologyCàncerUrban areasSocioeconomicsSmall-Area Analysismedia_common:Geographicals::Geographic Locations::Europe::Spain [Medical Subject Headings]Geography:Diseases::Neoplasms [Medical Subject Headings]CensusNeoplasiasGeography:Health Care::Environment and Public Health::Public Health::Epidemiologic Methods::Statistics as Topic::Probability::Bayes Theorem [Medical Subject Headings]lcsh:R858-859.7EnfermeríaFemaleRisk assessmentComputer Science(all)Riskmedicine.medical_specialtyGeneral Computer ScienceInequalitymedia_common.quotation_subjectHealth geographyeducationBayesian probabilityMedi ambientCancer mortalitylcsh:Computer applications to medicine. Medical informaticsRisk AssessmentCàncer -- MortalitatCiutatsMortalitatmedicineConfidence IntervalsTeorema de BayesHumansCancer -- MortalitySocioeconomic statusPovertyPovertybusiness.industryPublic healthResearchPublic Health Environmental and Occupational HealthCorrection:Health Care::Environment and Public Health::Public Health::Epidemiologic Measurements::Demography::Health Status::Health Status Disparities [Medical Subject Headings]Bayes TheoremHealth Status DisparitiesGeneral Business Management and AccountingSocioeconomic deprivationBayesian statistical decisionCross-Sectional StudiesEstadística bayesianaSocioeconomic FactorsSpainInequalitiesbusinessDemographyInternational Journal of Health Geographics
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Continuous Compared to Accumulated Walking-Training on Physical Function and Health-Related Quality of Life in Sedentary Older Persons

2020

The present study aimed to analyze the impact of overground walking interval training (WIT) in a group of sedentary older adults, comparing two different dose-distributions. In this quasi-experimental and longitudinal study, we recruited twenty-three sedentary older adults (71.00 &plusmn

MaleWeaknessmedicine.medical_specialtyLongitudinal studyHealth Toxicology and Mutagenesisphysical activitylcsh:MedicineWalkingArticleInterval trainingagility test03 medical and health sciencessymbols.namesake0302 clinical medicineQuality of lifemedicineHumansLongitudinal Studies030212 general & internal medicineExerciseolder adultsAgedMorningdose-responseAged 80 and overcardiorespiratory fitnessbusiness.industrypublic healthaginglcsh:RPublic Health Environmental and Occupational HealthCardiorespiratory fitnessPreferred walking speedBonferroni correctionexecutive functionCardiorespiratory FitnessPhysical FitnessQuality of LifesymbolsPhysical therapyFemalemedicine.symptomstrengthbusiness030217 neurology & neurosurgeryInternational Journal of Environmental Research and Public Health
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The Lich-Gregoir antireflux plasty: experiences with 371 children.

1978

AbstractThe Lich-Gregoir antireflux procedure is a simple and safe method for the treatment of primary reflux of all grades if the ureter is not grossly dilated on the excretory urogram. Reflux was cured in 97.7 per cent of 429 ureters in 371 children. A stenosis of the terminal ureter requiring reimplantation occurred in 0.5 per cent. The over-all rate of reinterventions was 3.7 per cent. This low complication rate makes surgical correction of reflux advisable if urinary tract infection and primary reflux cannot be eradicated by continuous antimicrobial therapy within 6 months.

Malemedicine.medical_specialtyAdolescentUrologyUrinary systemUrinary BladderUretermedicineMethodsHumansComplication rateChildVesico-Ureteral Refluxbusiness.industryRefluxInfantSurgical correctionmedicine.diseasedigestive system diseasesSurgeryStenosismedicine.anatomical_structureChild PreschoolFemaleUreterbusinessThe Journal of urology
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