Search results for "cover"
showing 10 items of 5959 documents
Cyclo- and Polyphosphazenes for Biomedical Applications
2022
Cyclic and polyphosphazenes are extremely interesting and versatile substrates characterized by the presence of -P=N- repeating units. The chlorine atoms on the P atoms in the starting materials can be easily substituted with a variety of organic substituents, thus giving rise to a huge number of new materials for industrial applications. Their properties can be designed considering the number of repetitive units and the nature of the substituent groups, opening up to a number of peculiar properties, including the ability to give rise to supramolecular arrangements. We focused our attention on the extensive scientific literature concerning their biomedical applications: as antimicrobial age…
Powietrze jako dolne źródło pompy ciepła
2016
W pracy przedstawiono wyniki analiz efektywności energetycznej wykorzystania do ogrzewania budynków jednorodzinnych oraz podgrzewania ciepłej wody użytkowej powietrznych pomp ciepła. Przedstawiono różne rozwiązania dolnych źródeł ciepła pompy wykorzystujących powietrze atmosferyczne lub powietrze z systemu wentylacji budynku. Dokonano również analizy okresu zwrotu inwestycji systemu ogrzewania z wykorzystaniem powietrznej pompy ciepła.
Inside Cover: Hydrogen-Bonded Open-Framework with Pyridyl-Decorated Channels: Straightforward Preparation and Insight into Its Affinity for Acidic Mo…
2017
International audience; A hydrogen-bonded open framework with pores decorated by pyridyl groups was constructed by off-charge-stoichiometry assembly of protonated tetrakis(4-pyridyloxymethyl)methane and [Al(oxalate)(3)](3-), which are the H-bond donor and acceptor of ionic H-bond interactions, respectively. This supramolecular porous architecture (SPA-2) has 1nm-large pores interconnected in 3D with large solvent-accessible void (53%). It demonstrated remarkable affinity for acidic organic molecules in solution, which was investigated by means of various carboxylic acids including larger drug molecules. Competing sorption between acetic acid and its halogenated homologues evidenced good sel…
Pressure support ventilation + sigh in acute hypoxemic respiratory failure patients: Study protocol for a pilot randomized controlled trial, the PROT…
2018
Background Adding cyclic short sustained inflations (sigh) to assisted ventilation yields optimizes lung recruitment, decreases heterogeneity and reduces inspiratory effort in patients with acute hypoxemic respiratory failure (AHRF). These findings suggest that adding sigh to pressure support ventilation (PSV) might decrease the risk of lung injury, shorten weaning and improve clinical outcomes. Thus, we conceived a pilot trial to test the feasibility of adding sigh to PSV (the PROTECTION study). Methods PROTECTION is an international randomized controlled trial that will be conducted in 23 intensive care units (ICUs). Patients with AHRF who have been intubated from 24 h to 7 days and under…
COVID-19 Lessons and Post-pandemic Recovery: A Case of Latvia.
2022
The research was supported by the NATIONAL RESEARCH PROGRAMME “LATVIAN HERITAGE AND FUTURE CHALLENGES FOR THE SUSTAINABILITY OF THE STATE” project “CHALLENGES FOR THE LATVIAN STATE AND SOCIETY AND THE SOLUTIONS IN INTERNATIONAL CONTEXT" (INTERFRAME-LV, Project No.VPP-IZM-2018/1-0005).
Returns To Education During And After The Economic Crisis: Evidence From Latvia 2006–2012
2017
We employ EU-SILC micro data for Latvia to study how returns to education changed during the economic crisis of 2008–2009 and afterwards. We found that returns to education increased significantly during the crisis and decreased slightly during the subsequent economic recovery. The counter-cyclical effect was evident in nearly all population groups. After the crisis, education became more associated than before with a longer working week and a higher employment probability. Furthermore, we show that returns to education in Latvia are generally higher in the capital city and its suburbs than outside the capital city region, as well as for citizens of Latvia than for resident non-citizens and…
Proteomics in antitumor research
2006
Proteins are the molecular players of fine-tuned regulatory pathways that underlie the behavior of any cell type. Derangement of this wide protein circuitry has a profound effect on cell life and ultimately contributes to the development of diseases such as cancer. New proteomic technologies are rapidly evolving to define and characterize the nodes of this altered protein network, both inside and outside cancer cells. Hopefully, these technologies will become user-friendly laboratory tools to improve cancer management from early detection to the development of rational and patient-tailored therapeutic strategies.
Spouses’ Experiences of Rehabilitees’ Burnout and Recovery
2021
The role of family members’ support in the burnout recovery process has been recognized in several studies. The role of emotional support provided by the spouse has been found to be significant in reducing burnout levels. Although crossover of burnout and emotional support have been investigated, the partners’ experiences of the individuals’ burnout and recovery have remained largely unexplored. To fill this research gap the study aims to provide in-depth knowledge of the experiences of spouses of individuals who have a history of burnout and are recovering from it by participating in a rehabilitation course. Ten spouses of individuals who had previously suffered and had recovered or was re…
Fighting Antibiotic Resistance: New Pyrimidine-Clubbed Benzimidazole Derivatives as Potential DHFR Inhibitors
2023
The present work describes the design and development of seventeen pyrimidine-clubbed benzimidazole derivatives as potential dihydrofolate reductase (DHFR) inhibitors. These compounds were filtered by using ADMET, drug-likeness characteristics calculations, and molecular docking experiments. Compounds 27, 29, 30, 33, 37, 38, and 41 were chosen for the synthesis based on the results of the in silico screening. Each of the synthesized compounds was tested for its in vitro antibacterial and antifungal activities using a variety of strains. All the compounds showed antibacterial properties against Gram-positive bacteria (Staphylococcus aureus and Staphylococcus pyogenes) as well as Gram-negativ…
Pankin pääomarakenne ja varainhankinta nykyisessä ja tulevassa pankkisääntelyssä
2017
Tämä tutkielma kokoaa yhteen pankkeja nykyisin velvoittavat pääomien määrään ja maksuvalmiuteen sekä rahoitukseen liittyvät sääntelyt. Tutkielman tavoitteena on saada vastaus kysymykseen: Miten pankin tulee huomioida pankkisääntely pääoman ja varainhankinnan rakenteessaan? Tutkielman alussa esitellään pankkitoimintaa yleisesti ja siihen liittyviä optimointiongelmia. Pankkien kannalta optimaalinen pääomarakenne poikkeaa sosiaalisesti optimaalisesta ja tätä varten pankkisääntelyä tarvitaan. Optimaalisimman tason määrittely on haastavaa, mutta sen on arvioitu olevan 15-20 % tasolla. Pääomarakenteella on vaikutusta pankin tuottavuuteen ja menestymisen mahdollisuuksiin. Pankkeja voidaan säännell…