Search results for "crystallin"
showing 10 items of 827 documents
Assessment of UV Biological Spectral Weighting Functions for Phenolic Metabolites and Growth Responses in Silver Birch Seedlings
2009
In research concerning stratospheric ozone depletion, action spectra are used as biological spectral weighting functions (BSWFs) for describing the effects of UV radiation on plant responses. Our aim was to evaluate the appropriateness of six frequently used BSWFs that differ in effectiveness with increasing wavelength. The evaluation of action spectra was based on calculating the effective UV radiation doses according to 1-2) two formulations of the generalized plant action spectrum, 3) a spectrum for ultraviolet induced erythema in human skin, 4) a spectrum for the accumulation of a flavonol in Mesembryanthemum crystallinum, 5) a spectrum for DNA damage in alfalfa seedlings and 6) the pla…
A microbiological, physicochemical, and texture study during storage of yoghurt produced under isostatic pressure
2019
Abstract This work aimed to study refrigeration storage (4 °C for 23 days) of yoghurt produced at 43 °C under sub-lethal high pressure, at 10, 20, 30 and 40 MPa, in comparison with the fermentation process at atmospheric pressure (0.1 MPa). Lactic acid bacteria (S. thermophilus and L. bulgaricus, LAB) and quality parameters like pH, titratable acidity, syneresis and colour were evaluated, along with textural analyses to infer how pressure would impact the obtained yoghurt along storage. Higher fermentation pressures resulted in slightly lower LAB loads (a maximum of 1.01 Log (CFU/mL)) and increased the fermentation time (a maximum of 3 h 25 min), syneresis (a maximum of 44%), all for 40 MPa…
Design of parallel compensator and stabilizing controller to mitigate non-minimum phase behaviour of the Czochralski Process
2020
Abstract This paper addresses the design of a parallel compensator and a stabilizing controller for the simplified crystal growth dynamics of the Czochralski (CZ) process, i.e., the process for the production of monocrystalline silicon ingots of uniform diameter. The diameter control of the produced ingots is achieved by a CCD camera measurement used to sense the radius of the boundary between the base of the growing crystal and the surrounding glowing meniscus — a raised melt surface connecting the crystal ingot with the flatter melt surface. Due to the intrinsic nature of the process, the bright ring radius measurement signal exhibits a non-minimum phase behaviour. A combination of the pa…
Influence of residual stress, surface roughness and crystallographic texture induced by machining on the corrosion behaviour of copper in salt-fog at…
2012
International audience; The influence of quadratic stress, crystallographic texture, lubrication and surface roughness generated by superfinish turning on the corrosion behaviour of pure copper was quantified in salt-fog atmosphere. This was done using statistical analysis (Pearson's correlation matrix). Three compounds were found after corrosion tests: atacamite/paratacamite and a black layer (mixture of the lubricant and the salt atmosphere). Surface characteristics were classified according to their decreasing influence on the formation of atacamite/paratacamite as follows: surface roughness and quadratic stress. Lubrication and the crystallographic texture have the lowest influence on c…
Impact des conditions d'usinage sur la zone du matériau affectée par le procédé
2007
Colloque avec actes et comité de lecture. Internationale.; International audience; Les procédés d'usinage peuvent créer des contraintes résiduelles à la surface des pièces usinées et ainsi modifier la microstructure et la texture de la matière proche de la surface. De tels changements sont importants pour l'étude du comportement des pièces au cours du temps. Il est alors nécessaire de quantifier les contraintes résiduelles, les composantes de texture et de déterminer la microstructure induite par l'usinage pour comprendre et prédire le comportement des surfaces considérées. Dans cette étude, le matériau cuivre pur a été choisi et considéré comme un "système modèle". En tournage, l'influence…
Non-essential role for cilia in coordinating precise alignment of lens fibres
2016
The primary cilium, a microtubule-based organelle found in most cells, is a centre for mechano-sensing fluid movement and cellular signalling, notably through the Hedgehog pathway. We recently found that each lens fibre cell has an apically situated primary cilium that is polarised to the side of the cell facing the anterior pole of the lens. The direction of polarity is similar in neighbouring cells so that in the global view, lens fibres exhibit planar cell polarity (PCP) along the equatorial-anterior polar axis. Ciliogenesis has been associated with the establishment of PCP, although the exact relationship between PCP and the role of cilia is still controversial. To test the hypothesis t…
Objective Assessment of Nuclear and Cortical Cataracts through Scheimpflug Images: Agreement with the LOCS III Scale.
2016
Purpose To assess nuclear and cortical opacities through the objective analysis of Scheimpflug images, and to check the correlation with the Lens Opacity Classification System III (LOCS III). Methods Nuclear and cortical opacities were graded according to the LOCS III rules after pupil dilation. The maximum and average pixel intensity values along an elliptical mask within the lens nucleus were taken to analyse nuclear cataracts. A new metric based on the percentage of opaque pixels within a region of interest was used to analyse cortical cataracts. The percentage of opaque pixels was also calculated for half, third and quarter areas from the region of interest’s periphery. Results The maxi…
αB-crystallin response to a pro-oxidant non-cytotoxic environment in murine cardiac cells: An "in vitro" and "in vivo" study.
2020
The αB-crystallin (HSPB5) protein is modulated in response to a wide variety of stressors generated by multiple physio-pathological conditions, sustained by reactive oxygen species (ROS) production. In cardiac muscle tissue, this protein regulates various cellular processes, such as protein degradation, apoptosis and the stabilization of cytoskeletal elements. In this work, we studied the role of HSPB5 expression, activation and localization in HL-1 murine cardiomyocytes exposed to pro-oxidant and non-cytotoxic H2O2 concentration, as well as in cardiac tissue isolated from mice following an acute, non-damaging endurance exercise. Our results demonstrated that HSPB5 is the most abundant HSP …
Application of chemometrics to assess the influence of ultrasound frequency, Lactobacillus sakei culture and drying on beef jerky manufacture: Impact…
2017
The effects of ultrasound (US) frequency, addition of Lactobacillus sakei culture and drying time on key nutritional (protein, amino acids, and organic acids) and physicochemical properties (texture and colour) of cultured and uncultured beef jerky were evaluated. Cultured and uncultured jerky samples were subjected to US frequencies of 25 kHz, 33 kHz and 45 kHz for 30 min prior to marination and drying. Principal component analysis demonstrated a significant effect of beef jerky processing conditions on physicochemical properties. Taurine content of jerky samples was found to increase with an increase in ultrasonic frequencies for cultured samples. No significant changes in colour values w…
The Small Heat Shock Protein α-Crystallin B Shows Neuroprotective Properties in a Glaucoma Animal Model
2017
Glaucoma is a neurodegenerative disease that leads to irreversible retinal ganglion cell (RGC) loss and is one of the main causes of blindness worldwide. The pathogenesis of glaucoma remains unclear, and novel approaches for neuroprotective treatments are urgently needed. Previous studies have revealed significant down-regulation of α-crystallin B as an initial reaction to elevated intraocular pressure (IOP), followed by a clear but delayed up-regulation, suggesting that this small heat-shock protein plays a pathophysiological role in the disease. This study analyzed the neuroprotective effect of α-crystallin B in an experimental animal model of glaucoma. Significant IOP elevation induced b…