Search results for "cycle"

2020

Purpose: To examine the potential sex differences in adaptations to combined endurance and strength training in recreationally endurance trained (eumenorrheic) women (n = 9) and men (n = 10). Methods: Isometric (ISOMmax) and dynamic bilateral leg press (1RM), countermovement jump (CMJ), running performance (3,000 m time trial), lean mass and body fat % (LEAN and FAT% determined by dual X-ray absorptiometry) as well as serum testosterone and cortisol (TES and COR, respectively, measured using hormone-specific immunoassay kits) were examined before a control period and pre, mid, and post a supervised 10-week combined high-intensity interval endurance training (4 × 4 min intervals and 3 × 3 × …

Autonomic, hormonal, and subjective responses to a modified version of the TSST: a pilot study

2021

El objetivo de esta investigación fue estudiar las respuestas hormonales, autonómicas y afectivas a una versión modificada del estresor TSST en una muestra de jóvenes universitarios compuesta de treinta y ocho sujetos (11 hombres y veintisiete mujeres, 11 en la fase lútea del ciclo menstrual, 16 mujeres en la fase folicular). La respuesta hormonal se evaluó con niveles de cortisol. La frecuencia cardíaca y la actividad electrodérmica se registraron durante toda la sesión experimental y la ansiedad rasgo y estado se evaluaron antes y después de la tarea. La fase de discurso provocó la frecuencia cardíaca más alta, la mayor frecuencia de respuestas inespecíficas y el mayor nivel de conductanc…

Life Cycle Assessment of repurposed electric vehicle batteries: an adapted method based on modelling energy flows

2018

Abstract After their first use in electric vehicles (EVs), the residual capacity of traction batteries can make them valuable in other applications. Although reusing EV batteries remains an undeveloped market, second-use applications of EV batteries are in line with circular economy principles and the waste management hierarchy. Although substantial environmental benefits are expected from reusing traction batteries, further efforts are needed in data collection, modelling the life-cycle stages and calculating impact indicators to propose a harmonized and adapted life-cycle assessment (LCA) method. To properly assess the environmental benefits and drawbacks of using repurposed EV batteries …

Reuse of electric vehicle batteries in buildings: An integrated load match analysis and life cycle assessment approach

2019

Abstract The increasing use of renewable energy technologies for electricity generation in buildings will require a growing number of battery energy storage systems (BESS) to enhance the reliability of electricity supply. The increasing number of retired electric vehicle (EV) batteries, expected from the automotive sector, can match this demand as EV batteries can be used as BESS, considering that they have about 80% of their original energy capacity. In this context, the study aims at examining the system, consisting of a BESS made by retired Li-ion EV batteries, a photovoltaic plant (20 kW) and the electricity grid, that provides the electricity required by an existing nearly net zero res…

Design and Modeling of an Interleaving Boost Converter with Quasi-Saturated Inductors for Electric Vehicles

2020

This paper is focused on the analysis and modeling of DC-DC boost converters in interleaving configuration exploiting inductors in the quasi-saturation region. The converter is designed to optimize the power density by minimizing the size of the inductors. A simulation study for electric vehicle applications is conducted analyzing the effects of duty cycle and temperature variation on the ripple of the input current giving, moreover, information on the performances and dynamics of the converter for further implementation and optimizations.

CCDC 1524058: Experimental Crystal Structure Determination

2017

UDAKUI : 6,12,18,24-tetramethoxy-2,8,14,20-tetrapropyl-4,10,16,22-tetrahydroxycalix[4]arene acetone solvate Space Group: P21/n, Cell: a 11.7707(4)Å b 17.4447(6)Å c 21.7775(7)Å, α 90.00° β 105.261(2)° γ 90.00° Work published 2017 via Cambridge Crystallographic Data Centre.

AQUEOUS EXTRACTS FROM LEAVES AND RHIZOMES OF THE MARINE SEAGRASS POSIDONIA OCEANICA EXHIBIT ANTI-LIVER CANCER ABILITY IN VITRO

2022

Effective targeting of breast cancer stem cells by combined inhibition of Sam68 and Rad51

2022

AbstractBreast cancer (BC) is the second cause of cancer-related deceases in the worldwide female population. Despite the successful treatment advances, 25% of BC develops resistance to current therapeutic regimens, thereby remaining a major hurdle for patient management. Current therapies, targeting the molecular events underpinning the adaptive resistance, still require effort to improve BC treatment. Using BC sphere cells (BCSphCs) as a model, here we showed that BC stem-like cells express high levels of Myc, which requires the presence of the multifunctional DNA/RNA binding protein Sam68 for the DNA-damage repair. Analysis of a cohort of BC patients displayed that Sam68 is an independen…

MicroRNA-29b-1 impairs in vitro cell proliferation, self‑renewal and chemoresistance of human osteosarcoma 3AB-OS cancer stem cells

2014

Osteosarcoma (OS) is the most common type of bone cancer, with a peak incidence in the early childhood. Emerging evidence suggests that treatments targeting cancer stem cells (CSCs) within a tumor can halt cancer and improve patient survival. MicroRNAs (miRNAs) have been implicated in the maintenance of the CSC phenotype, thus, identification of CSC-related miRNAs would provide information for a better understanding of CSCs. Downregulation of miRNA-29 family members (miR-29a/b/c; miR‑29s) was observed in human OS, however, little is known about the functions of miR-29s in human OS CSCs. Previously, during the characterization of 3AB-OS cells, a CSC line selected from human OS MG63 cells, we…

TAZ is required for metastatic activity and chemoresistance of breast cancer stem cells

2015

Metastatic growth in breast cancer (BC) has been proposed as an exclusive property of cancer stem cells (CSCs). However, formal proof of their identity as cells of origin of recurrences at distant sites and the molecular events that may contribute to tumor cell dissemination and metastasis development are yet to be elucidated. In this study, we analyzed a set of patient-derived breast cancer stem cell (BCSC) lines. We found that in vitro BCSCs exhibit a higher chemoresistance and migratory potential when compared with differentiated, nontumorigenic, breast cancer cells (dBCCs). By developing an in vivo metastatic model simulating the disease of patients with early BC, we observed that BCSCs…