Search results for "cyclic"

showing 10 items of 2439 documents

The Major Heat Shock Proteins, Hsp70 and Hsp90, in 2-Methoxyestradiol-Mediated Osteosarcoma Cell Death Model

2020

2-Methoxyestradiol is one of the natural 17&beta

neuronal nitric oxide synthaseProgrammed cell death2-methoxyestradiolLactams MacrocyclicAntineoplastic AgentsBone NeoplasmsModels BiologicalArticleCatalysisHsp90 inhibitorNitric oxidelcsh:ChemistryInorganic Chemistrychemistry.chemical_compoundDownregulation and upregulationosteosarcomaHeat shock proteinBenzoquinonesAnimalsHumansDrug InteractionsHSP70 Heat-Shock ProteinsHSP90 Heat-Shock ProteinsPhysical and Theoretical Chemistrygeldanamycinlcsh:QH301-705.5Molecular BiologySpectroscopyAntibiotics AntineoplasticbiologyOrganic ChemistryGeneral MedicineGeldanamycinHsp90Computer Science ApplicationsHsp70lcsh:Biology (General)lcsh:QD1-999chemistryCancer researchbiology.proteinInternational Journal of Molecular Sciences
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Haptotropism in a Nickel Complex with a Neutral, π‐Bridging cyclo‐P4 Ligand Analogous to Cyclobutadiene

2022

The reaction of ( 1 )Ni(η 2 -cod), 2 , incorporating a chelating bis( N -heterocyclic carbene) 1 , with P 4 in pentane yielded the dinuclear complex [( 2 )Ni] 2 (μ 2 ,η 2 :η 2 -P 4 ), 3 , formally featuring a cyclobutadiene-like, neutral, rectangular, π-bridging P 4 -ring. In toluene, the butterfly-shaped complex [( 1 )Ni] 2 (μ 2 ,η 2 :η 2 -P 2 ), 4 , with a formally neutral P 2 -unit was obtained from 2 and either P 4 or 3 . Computational studies showed that a low energy barrier haptotropic rearrangement involving two isomers of the μ 2 ,η 2 :η 2 -P 4 coordination mode and a low energy μ 2 ,η 4 :η 4 -P 4 coordination mode, as previously predicted for related nickel cyclobutadiene complexes…

nickelkompleksiyhdisteetphosphorushaptotropismnikkeliN-heterocyclic carbenefosforiπ-ligands
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Comparison of oxidoreductive enzyme activities in three coal tar creosote-contaminated soils

2019

This study used laboratory experiments to compare the effects of coal tar creosote on the activity of oxidoreductive enzymes in sandy loam, loamy sand and sandy clay loam soils. Different amounts of coal tar creosote were added to soil samples as follows: 0 (control), 2, 10 or 50 g kg–1 dry matter. The activity of soil dehydrogenases (DHAs), o-diphenol oxidase (o-DPO), catalase (CAT), nitrate reductase (NR) and peroxidases (POX) was determined. Contamination of soil with coal tar creosote affected oxidoreductase activity. Oxidoreductive enzyme activity following soil contamination with coal tar creosote was in the following order: DHAs > CAT > NR > POX > o-DPO in…

nitrate reductaseSoil testvirusespolycyclic aromatic hydrocarbonsSoil Science010501 environmental sciencesEnvironmental Science (miscellaneous)Nitrate reductasecomplex mixtures01 natural scienceslaw.inventionresistance indexBioremediationlawotorhinolaryngologic diseasesmedicineCoal tar0105 earth and related environmental sciencesEarth-Surface ProcessesChemistrycatalasedehydrogenases04 agricultural and veterinary sciencesSoil contaminationCreosoteEnvironmental chemistryLoamSoil water040103 agronomy & agriculture0401 agriculture forestry and fisheriesperoxidasesmedicine.drugSoil Research
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Diels–Alder reaction of β-fluoro-β-nitrostyrenes with cyclic dienes

2021

The Diels–Alder reaction of β-fluoro-β-nitrostyrenes with cyclic 1,3-dienes was investigated. A series of novel monofluorinated norbornenes was prepared in up to 97% yield. The reaction with 1,3-cyclohexadiene permits the preparation of monofluorinated bicyclo[2.2.2]oct-2-enes. The kinetic data of the reactions with 1,3-cyclopentadiene and 1,3-cyclohexadiene were used to calculate activation parameters. Furthermore, the synthetic utility of the cycloadducts obtained was demonstrated.

nitrostyreneBicyclic moleculeChemistryOrganic Chemistrystereochemistrychemistry.chemical_elementnorborneneMedicinal chemistryFull Research Paperlcsh:QD241-441Chemistrychemistry.chemical_compoundlcsh:Organic chemistryDiels–Alder reactionfluorineYield (chemistry)Fluorinelcsh:Qlcsh:ScienceNorborneneDiels–Alder reactionBeilstein Journal of Organic Chemistry
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Group Identities on Units of Group Algebras

2000

Abstract Let U be the group of units of the group algebra FG of a group G over a field F . Suppose that either F is infinite or G has an element of infinite order. We characterize groups G so that U satisfies a group identity. Under the assumption that G modulo the torsion elements is nilpotent this gives a complete classification of such groups. For torsion groups this problem has already been settled in recent years.

p-groupAlgebra and Number TheoryDicyclic groupG-module010102 general mathematicsPerfect groupCyclic group010103 numerical & computational mathematics01 natural sciencesNon-abelian groupCombinatoricsInfinite groupIdentity component0101 mathematicsMathematicsJournal of Algebra
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Abelian Sylow subgroups in a finite group, II

2015

Abstract Let p ≠ 3 , 5 be a prime. We prove that Sylow p-subgroups of a finite group G are abelian if and only if the class sizes of the p-elements of G are all coprime to p. This gives a solution to a problem posed by R. Brauer in 1956 (for p ≠ 3 , 5 ).

p-groupCombinatoricsMathematics::Group TheoryNormal p-complementAlgebra and Number TheoryLocally finite groupSylow theoremsCyclic groupElementary abelian groupOmega and agemo subgroupAbelian groupMathematicsJournal of Algebra
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Jana Pawła II ekumeniczna wizja Kościoła

2016

Artykuł nie podsumowuje długiego i bardzo bogatego w wiele ekumenicznych inicjatyw pontyfikatu Jana Pawła II. Prezentując jego ekumeniczną wizję Kościoła, ogranicza się do czterech punktów. Wylicza główne dokumenty ekumeniczne napisane przez Papieża (1), bardziej szczegółowo omawia treść listu apostolskiego Orientale lumen (2) i encykliki Ut unum sint (3). W ostatnim punkcie wyodrębnia elementy oryginalne, które w prezentowanej encyklice dotyczą Papieża i papiestwa (4). W formie wniosku stwierdzona, że z dokumentów ekumenicznych pozostawionych przez Jana Pawła II tchnie ogromny potencjał jego intelektualnej i kościelnej otwartości, odwagi oraz ekumenicznej nadziei.

papacyJan Paweł IIecumenical documentsKościółencyklika Ut unum sintJohn Paul IIList apostolski Orientale lumenpapiestwoApostolic Letter Orientale lumenChurchEncyclica Ut unum sintekumeniczne dokumentyStudia Oecumenica
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Synthesis, characterization, and cellular investigations of porphyrin– and chlorin–indomethacin conjugates for photodynamic therapy of cancer

2021

Indomethacin is a potent non-steroidal anti-inflammatory drug (NSAID) with a strong selective inhibitor activity towards cyclooxygenase-2 (COX-2), an enzyme that is highly overexpressed in various tumour cells, being involved in tumourigenesis. Concomitantly, porphyrins have gained much attention as promising photosensitizers (PSs) for the non-invasive photodynamic therapy (PDT) of cancer. Herein, we report the design, and determine the singlet oxygen generation capacity and in vitro cellular toxicity of porphyrin- and chlorin-indomethacin conjugates (P2-Ind and C2-Ind). Both the conjugates were obtained in high yields and were characterized by 1H, 19F and 13C NMR as well as by high resolut…

photosensitizermedicine.medical_treatmentPhotodynamic therapyDFT calculations010402 general chemistryPhotochemistry01 natural sciencesBiochemistrychemistry.chemical_compoundnon-steroidal anti-inflammatory drugpolycyclic compoundsmedicinePhysical and Theoretical ChemistryTriplet stateCytotoxicity010405 organic chemistrySinglet oxygenOrganic Chemistrysinglet oxygen generationPorphyrin0104 chemical sciencesPhotochemotherapychemistrySettore CHIM/03 - Chimica Generale E InorganicaChlorincytotoxicityPhototoxicityporphyrinConjugateOrganic & Biomolecular Chemistry
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Facile and efficient chemical functionalization of aliphatic polyesters by cross metathesis

2016

International audience; An effective preparation of new tailor-made macromolecular materials via a combination of two (atom-efficient) catalytic transformations is reported. First, new aliphatic polyesters with alternated composition have been prepared using a salen aluminum catalyst system. Next, the pendant vinyl moieties in those copolymers have been selectively transformed into various functional groups by metathesis in the presence of homogeneous Grubbs catalysts. The latter metathesis reaction has been optimized in terms of catalytic activity and selectivity, to define the conditions for an effective and safe procedure that does not affect the macromolecular architecture. All polymer …

plga microspheresphosphate-buffered solutionin-vivo degradationPolymers and PlasticsBioengineeringmolecular-weight poly(l-lactide)010402 general chemistryMetathesis01 natural sciencesBiochemistry[ CHIM ] Chemical SciencesCatalysisacid) microspheresCopolymerSalt metathesis reactionenzymatic degradation[CHIM]Chemical SciencesOrganic chemistryRing-opening metathesis polymerisationcyclic anhydrides010405 organic chemistryChemistryring-opening copolymerizationOrganic Chemistryrenewable resources0104 chemical sciencesPolyester[ CHIM.POLY ] Chemical Sciences/Polymers[CHIM.POLY]Chemical Sciences/Polymersbiodegradable polymersSelectivityAcyclic diene metathesis
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Identification of Polycyclic Aromatic Hydrocarbons (PAHs) in the black crusts of Sicilian stone monuments: distribution and sources

2004

Polycyclic Aromatic Hydrocarbons are a family of compounds with known carcinogenic potential; their properties of lipophilicity, low water solubility and adsorption to particles and sediments make them a potentially dangerous group of chemicals and a threat to the environment and its bio-resources. The concentrations of total Polycyclic Aromatic Hydrocarbons (PAHs) and 19 individual compounds in 8 black crusts sampled from historical building of Palermo (Italy) were analyzed, by gas chromatography/mass spectrometry (GC/MS) in selected ion monitoring (SIM) mode. PAH concentrations ranged from 78 to 9798 g/Kg of dry matrix. The resulting distributions and molecular ratios of specific compo…

polycyclic aromatic hydrocarbons black crusts organic matter Palermo.Settore CHIM/12 - Chimica Dell'Ambiente E Dei Beni Culturali
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