Search results for "cyclic"

showing 10 items of 2439 documents

Dialkyl(butadiene)cyclopentadienylmolybdenum(III) Complexes. Synthesis, Characterization, and Reactivity

2000

International audience; Treatment of CpMo(η4-diene)Cl2 (diene = 1,3-butadiene, C4H6, 1‘; isoprene, C5H8, 1‘ ‘; 2,3-dimethyl-1,3-butadiene, C6H10, 1‘ ‘) in diethyl ether at low temperature with 2 equiv of alkylmagnesium RMgX reagents affords the corresponding dialkyl complexes CpMo(η4-1,3-diene)R2 (2, 2‘, 2‘ ‘, R = CH3, a; CH2Ph, b; CH2SiMe3, c). These species are isolable in moderate yields and have been fully characterized by EPR, elemental analyses, and cyclic voltammetry. They all show a reversible reduction process at relatively low potentials and an irreversible oxidation. The structure of 2‘ ‘a was confirmed by single-crystal X-ray diffraction. The mixed complex CpMo(η4-C4H6)Cl(CH3), …

DieneStereochemistryReaction productsLigands010402 general chemistry01 natural sciencesMedicinal chemistryInorganic Chemistrychemistry.chemical_compound[CHIM.CRIS]Chemical Sciences/Cristallography[CHIM.COOR]Chemical Sciences/Coordination chemistryRedistribution (chemistry)Redox reactionsPhysical and Theoretical ChemistryIsoprene010405 organic chemistryLigandArylOrganic ChemistryAlkyls0104 chemical scienceschemistryReagentCyclic voltammetryDiethyl etherElectron paramagnetic resonance spectroscopyOrganometallics
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Reactions of Alkenes and Alkynes with an Acyclic Silylene and Heavier Tetrylenes under Ambient Conditions

2014

Cycloaddition reactions of the acyclic silylene Si(SAriPr4)2 (AriPr4 = C6H3-2,6(C6H3-2,6-iPr2)2) with a variety of alkenes and alkynes were investigated. Its reactions with the alkynes phenylacetylene and diphenylacetylene and the diene 2,3-dimethyl-1,3-butadiene yielded silacycles (AriPr4S)2tiebar above startSi(CH═tiebar above endCPh) (1), (AriPr4S)2tiebar above startSi(PhC═tiebar above endCPh) (2), and (AriPr4S)2tiebar above startSiCH2CMeCMetiebar above endCH2 (3) at ambient temperature. The compounds were characterized by X-ray crystallography, 1H, 13C, and 29Si NMR spectroscopy, and IR spectroscopy. No reaction was observed with more substituted alkenes such as propene, (Z)-2-butene, te…

DieneTrimethylsilylacyclic silyleneAlkynealkeenit ja alkyynitPhotochemistryMedicinal chemistryInorganic Chemistrychemistry.chemical_compoundraskaammat tetryleenitalkenes and alkynesCyclopenteneambient conditionssykloadditioreaktiotPhysical and Theoretical Chemistryasyklinen silyleeniDiphenylacetyleneta116chemistry.chemical_classificationOrganic ChemistrySilylenecyloaddition reactionsCycloadditionPhenylacetylenechemistrynormaalit ympäristön olosuhteethevier tetrylenes
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Electron diffraction, X-ray powder diffraction and pair-distribution-function analyses to determine the crystal structures of Pigment Yellow 213, C23…

2009

The crystal structure of the nanocrystalline alpha phase of Pigment Yellow 213 (P.Y. 213) was solved by a combination of single-crystal electron diffraction and X-ray powder diffraction, despite the poor crystallinity of the material. The molecules form an efficient dense packing, which explains the observed insolubility and weather fastness of the pigment. The pair-distribution function (PDF) of the alpha phase is consistent with the determined crystal structure. The beta phase of P.Y. 213 shows even lower crystal quality, so extracting any structural information directly from the diffraction data is not possible. PDF analysis indicates the beta phase to have a columnar structure with a si…

DiffractionModels MolecularAza CompoundsReflection high-energy electron diffractionChemistryMolecular ConformationGeneral MedicineCrystal structurePair-distribution functionHeterocyclic Compounds 4 or More RingsGeneral Biochemistry Genetics and Molecular BiologyPigment Yellow 213CrystalCrystallinityCrystallographyElectron diffractionElectron diffractionMicroscopy Electron TransmissionX-ray powder diffractionElectron diffraction; Pair-distribution function; Pigment Yellow 213; X-ray powder diffractionParticle SizeColoring AgentsPowder diffractionPowder DiffractionElectron backscatter diffractionActa crystallographica. Section B, Structural science
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Induction of digoxin-like material production, and the digoxin binding in the unicellular organism Tetrahymena by digitoxin.

1998

Thin layer chromatographic, and laser-confocal microscopic analyses with a monoclonal antibody to digoxin also displaying high affinity to digoxigenin, were used to determine the presence and localization of cardioactive glycosides. Tetrahymena pyriformis was found to possess digitoxigenin-like material, but digoxin, digitoxin, digoxigenin, gitoxin and lanatoside C were not detected. Digitoxin treatment elicited the appearance of a digoxin-like material in the progeny generations. Digoxin was taken up by untreated Tetrahymena, especially strongly 24 h after digitoxin treatment. While the cardenolide was localized in vesicles of the cell body in untreated Tetrahymena, the engulfed digoxin ap…

DigoxinDigoxinDigitoxinBiologychemistry.chemical_compoundDigitoxinpolycyclic compoundsmedicineCardenolideDigoxigeninAnimalscardiovascular diseasesChromatography High Pressure Liquidchemistry.chemical_classificationBinding SitesMicroscopy ConfocalTetrahymena pyriformisdigestive oral and skin physiologyCell MembraneLanatoside CTetrahymenaDigitalis GlycosidesBiological TransportCell BiologyGeneral Medicinebiology.organism_classificationImmunohistochemistrycarbohydrates (lipids)EnzymechemistryBiochemistryTetrahymena pyriformiscirculatory and respiratory physiologymedicine.drugCell biology international
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Digoxin and digitoxin elimination in man by charcoal hemoperfusion

1978

Since there is no widely used causal means of reducing the severity of massive digitalis intoxication the capability of hemoperfusion with coated activated charcoal to remove toxicologically relevant amounts of digoxin and digitoxin was evaluated in vitro and in man. At a blood flow rate of 100 ml/min the digoxin clearance by hemoperfusion in vitro was 51±8 ml/min in comparison to 24.3±11.3 ml/min by hemodialysis. The average hemoperfusion clearance of digitoxin was 31.7±13.4 ml/min, whereas almost no digitoxin was removed by hemodialysis. These clearance values point to the ability of hemoperfusion of eliminating digitalis glycosides from the blood. They do not clarify the essential questi…

DigoxinDigoxinDigitoxinmedicine.medical_treatmentBolus (medicine)DigitoxinDrug Discoverypolycyclic compoundsmedicineHumansGenetics (clinical)business.industryPoisoningGeneral MedicineBlood flowHemoperfusionHemoperfusioncarbohydrates (lipids)Activated charcoalCharcoalAnesthesiaToxicityMolecular MedicineHemodialysisbusinessmedicine.drugKlinische Wochenschrift
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A new synthetic entry into the tricyclo[3.3.0.03,7] octane skeleton

1987

Abstract A short synthesis of dimethyl tricyclo[3.3.0.03,7] octane-1,5-dicarboxylate, 13 , and its 3,7-dimethyl-derivative, 14 , by iodine oxidation of the bis-enolate derived from the corresponding dimethyl cis -bicyclo[3.3.0] octane-3,7-dicarboxylate, 11 or 12 , is described.

Diketonechemistry.chemical_compoundBicyclic moleculeChemistryOrganic ChemistryDrug DiscoveryOrganic chemistrySkeleton (category theory)BiochemistryPolyquinaneOctane
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Electrochemical reduction properties of A-frame compounds and crystal structure of Pd2(dppm)2(Me)2(Br)+ dimer

2006

Abstract Two series of A-frame complexes, [Pd2(dppm)2(R)2(μ-X)]+ (R = Me and X = Cl, Br, I, H; R = Mes and X = Br, I), were investigated by cyclic voltammetry (CV). The 2-electron reduction potentials for the first series increase from I (−1.10), Br (−1.17), Cl (−1.25) to H (−1.65 V versus SCE, in CHCl3), as well as in the second series; Br (−1.35) and I (−1.38 V versus SCE, in THF). The nature of the LUMO where the electron reduction takes place is qualitatively addressed by DFT on the corresponding model complexes [Pd2(H2PCH2PH2)2(R)2(μ-X)]+. The LUMO and (LUMO + 1) of the halide derivatives exhibit the presence of Pd d x 2 - y 2 atomic orbitals interacting in an anti-bonding fashion with…

DimerCrystal structure[CHIM.INOR]Chemical Sciences/Inorganic chemistry010402 general chemistryElectrochemistry01 natural sciencesInorganic Chemistrychemistry.chemical_compoundMaterials ChemistryReactivity (chemistry)Molecular orbitalA-framePhysical and Theoretical ChemistryHOMO/LUMOComputingMilieux_MISCELLANEOUSX-ray crystallography010405 organic chemistryChemistrymolecular orbitals[ CHIM.INOR ] Chemical Sciences/Inorganic chemistrypalladium0104 chemical sciences3. Good healthCrystallographyelectrochemistryX-ray crystallographyCyclic voltammetryInorganica Chimica Acta
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Versatile redox reactivity of triaryl-meso-substituted Ni(ii) porphyrin

2014

The electrochemical oxidation of nickel(II) 5,15-p-ditolyl-10-phenylporphyrin (1-Ni) leads to the formation of different coupling products, with the distribution depending on the nature of the solvent (CH2Cl2–CH3CN, CH2Cl2, DMF), the cell configuration (2 or 3 compartments) and the number of electrons abstracted. In a two compartment configuration (anode and cathode in the same compartment) in a CH2Cl2–CH3CN mixture, nickel(II) 5-chloro-10,20-p-ditolyl-15-phenylporphyrin (1-Ni-Cl) was isolated in good yield and its mechanism of formation is proposed. Switching to the three compartment configuration, the meso-β/meso-β doubly fused dimer (3-Ni) is detected as the major product whereas in pure…

DimerInorganic chemistrychemistry.chemical_elementRedoxInorganic ChemistryNickelchemistry.chemical_compoundchemistryYield (chemistry)Polymer chemistryReactivity (chemistry)PhosphoniumCyclic voltammetryTriphenylphosphineDalton Trans.
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Cobalt-Containing Silicotungstate Sandwich Dimer [{Co3(B-β-SiW9O33(OH))(B-β-SiW8O29(OH)2)}2]22-

2005

The 6-cobalt-substituted [{Co3(B-beta-SiW9O33(OH))(B-beta-SiW8O29(OH)2)}2]22- has been characterized by IR and UV-vis spectroscopy, elemental analysis, magnetic studies, electrochemistry, and gel filtration chromatography. A single-crystal X-ray analysis was carried out on K10Na12[{Co3(B-beta-SiW9O33(OH))(B-beta-SiW8O29(OH)2)}2].49H2O (KNa-1), which crystallizes in the monoclinic system, space group P2(1)/n, with a=19.9466(8) A, b=24.6607(10) A, c=34.0978(13) A, beta=102.175(1) degrees, and Z=2. Polyanion 1 represents a novel class of asymmetric sandwich-type polyanions. It contains three cobalt ions, which are encapsulated between an unprecedented (B-beta-SiW9O34) fragment and a (B-beta-Si…

DimerSize-exclusion chromatographyAnalytical chemistrySolid-statechemistry.chemical_elementElectrochemistryInorganic Chemistrychemistry.chemical_compoundCrystallographychemistryPhysical and Theoretical ChemistryCyclic voltammetrySpectroscopyCobaltMonoclinic crystal systemInorganic Chemistry
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Enzymatic esterification of bicyclic meso-diols derived from 1,4-bis(hydroxymethyl)furan. An enantioselective Diels–Alder reaction equivalent

1998

Abstract meso -Diols derived from the Diels–Alder adduct 1,4-bis(hydroxymethyl)furan/dimethyl acetylenedicarboxylate can be enantioselectively monoacetylated under CRL or PSL catalysis with very good yields and moderate to excellent ees. (+)-Monoacetates are always preferentially formed in the reactions catalyzed by CRL, and their (−)-enantiomers are the main products in the acetylations under PSL catalysis. Absolute configurations have been determined by X-ray analysis of a single crystal of an ( R )-α-methoxyphenylacetyl derivative.

Dimethyl acetylenedicarboxylateBicyclic moleculeChemistryOrganic ChemistryEnantioselective synthesisMedicinal chemistryCatalysisAdductInorganic Chemistrychemistry.chemical_compoundFuranHydroxymethylPhysical and Theoretical ChemistryDerivative (chemistry)Diels–Alder reactionTetrahedron: Asymmetry
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