Search results for "cyclic"

showing 10 items of 2439 documents

Triazolopyridines. Part 11. Ylides derived from 2-Acylmethyltriazolopyridinium salts.

1991

Abstract Ylides derived from 2-acylmethyltriazolopyridinium salts (2a) -(2c) react with methyl or ethyl propiolate and with dimethyl acetylenedicarboxylate to give ylides (3a)–(3e), (6) or (7). In some cases 1:2 adducts are formed, shown to be the novel ylides (8a)–(8d); an X-ray diffraction confirms structure (8a).

Dimethyl acetylenedicarboxylateBicyclic moleculeOrganic ChemistryCrystal structureNuclear magnetic resonance spectroscopyBiochemistryMedicinal chemistryAdductEthyl propiolatechemistry.chemical_compoundchemistryDrug DiscoveryX-ray crystallographyMichael reactionTetrahedron
researchProduct

Cycloaddition reactions. A new type of cycloadduct from a substituted 2-vinylthiophen and dmad

1987

Abstract Cycloaddition reactions between 2-(1-cyanoallyl)thiophen and the dienophiles diethyl azodicarboxylate, N-phenylmaleimide , methyl propiolate, and dimethyl acetylenedicarboxylate are reported. Products include simple benzo[b] thiophen carboxylates (13,19) and reduced derivatives (8,9,10,12,18), as a mixture of diastereoisomers, except in the adduct with diethyl azodicarboxylate. With dimethyl acetylenedicarboxylate a new type of tricyclic compound was also found (20).

Dimethyl acetylenedicarboxylateBicyclic moleculeOrganic ChemistryDiastereomerNuclear magnetic resonance spectroscopyBiochemistryCycloadditionAdductDiethyl azodicarboxylatechemistry.chemical_compoundchemistryDrug DiscoveryOrganic chemistryAliphatic compoundTetrahedron
researchProduct

Cycloaddition Reactions with Vinyl Heterocycles

1995

Publisher Summary The Diels-Alder reaction is one of the most common and elegant methods for the construction of six-membered rings. Although the number of Diels-Alder cycloadditions with open-chain and alicyclic dienes is very large, the number of examples with aromatic heterocyclic compounds is relatively small. The introduction of a vinyl group as a substituent onto a heterocycle increases the number of possible reactions. This new possibility, however attractive for synthetic purposes, is successful only with π-excessive five-membered heterocyclic derivatives with a few exceptions. The chapter discusses the reactions of vinyl heterocycles with carbodienophiles. The endocyclic and exo-en…

Dimethyl acetylenedicarboxylatechemistry.chemical_classificationchemistry.chemical_compoundAlicyclic compoundchemistryDienePolymerizationYield (chemistry)SubstituentOrganic chemistrySelectivityCycloaddition
researchProduct

Cycloaddition reactions of 2-vinylthiophen

1985

Abstract Cycloaddition reactions between 2-vinylthiophen and the dienophiles maleic anhydride, dimethyl acetylenedicarboxylate,' methyl propiolate, and methyl acrylate, are reported. Products include simple benzo[b]thiophen carboxylates (6, 13, 17) and reduced derivatives (3, 4, 18). The acetylenic dienophiles also gave a dihydrobenzthienyl-acrylate (16) or -fumarate (11), and the dithienylcyclohexene esters (7) and (14).

Dimethyl acetylenedicarboxylatechemistry.chemical_compoundBicyclic moleculeChemistryMethyl propiolateOrganic ChemistryDrug DiscoveryOrganic chemistryMaleic anhydrideDehydrogenationMethyl acrylateBiochemistryCycloadditionTetrahedron
researchProduct

Theoretical study on the mechanism of the domino reactions of tertiary α-cyano-enamines and dimethyl acetylenedicarboxylate

2001

Abstract The mechanisms of the domino reaction between dimethyl acetylenedicarboxylate, 1 , and 2-( N , N -dimethylamino)acrylonitrile, 2 , and these in presence of acrylonitrile have been theoretically studied using ab initio methods. These domino reactions comprise several pericyclic-type reactions. The geometrical and electronic analysis of the HF/6-31G ∗ transition structures and intermediates allows characterizing the processes that take place along these domino reactions. B3LYP/6-31G ∗ energetic results are in agreement with the experimental outcomes.

Dimethyl acetylenedicarboxylatechemistry.chemical_compoundPericyclic reactionchemistryCascade reactionComputational chemistryOrganic ChemistryDrug DiscoveryAb initioAcrylonitrileBiochemistryDominoTetrahedron
researchProduct

Acyl-Chain Mismatch Driven Superlattice Arrangements in DPPC/DLPC/Cholesterol Bilayers

2010

Fluorescence and infrared spectroscopy and cholesterol oxidase activity were employed to investigate the effect of phosphatidylcholine (PC) acyl chain length mismatch on the lateral organizations of lipids in liquid-ordered dipalmitoyl-PC/dilauroyl-PC/cholesterol (DPPC/DLPC/CHOL) bilayers. Plots of steady-state fluorescence emission anisotropy of diphenylhexatriene (DPH) labeled PC (DPH-PC) embedded in the DPPC/DLPC/CHOL bilayers revealed significant peaks at several DPPC mole fractions (Y(DPPC)) when the cholesterol mole fraction (X(CHOL)) was fixed to particular values. Analogously, the DPH-PC anisotropy peaked at several critical X(CHOL)'s when Y(DPPC) was fixed. Acyl chain C-H and C hor…

Diphenylhexatriene12-DipalmitoylphosphatidylcholineCholesterol oxidaseSuperlatticeLipid BilayersAnalytical chemistryInfrared spectroscopyFluorescence Polarization010402 general chemistryMole fraction01 natural sciencesArticle03 medical and health scienceschemistry.chemical_compoundPhosphatidylcholineSpectroscopy Fourier Transform Infraredpolycyclic compoundsMaterials ChemistryPhysical and Theoretical ChemistryLipid bilayer030304 developmental biology0303 health sciencesCholesterol OxidaseCholesteroltechnology industry and agriculture0104 chemical sciencesSurfaces Coatings and FilmsCrystallographyCholesterolchemistryCholesterol oxidase activity13. Climate actionAcyl chainPhosphatidylcholineslipids (amino acids peptides and proteins)Fluorescence anisotropyThe Journal of Physical Chemistry B
researchProduct

Time-resolved fluorescence and fourier transform infrared spectroscopic investigations of lateral packing defects and superlattice domains in composi…

2003

Time-resolved fluorescence and Fourier transform infrared spectroscopies were used to investigate the lateral organization of lipids in compositionally uniform and fully equilibrated 1-palmitoyl-2-oleoyl-phosphatidylcholine/cholesterol (POPC/CHOL) liposomes prepared by a recently devised low-temperature trapping method. Independent fluorescence decay lifetime and rotational dynamics parameters of diphenylhexatriene (DPH) chain-labeled phosphatidylcholine (DPH-PC) in these liposomes were recovered from the time-resolved fluorescence measurements as a function of cholesterol molar fraction (X(CHOL)) at 23 degrees C. The results indicate significantly greater lifetime heterogeneity, shorter av…

DiphenylhexatrieneModels MolecularMacromolecular SubstancesMembrane FluidityLipid BilayersBiophysicsAnalytical chemistry010402 general chemistryMole fraction01 natural sciences03 medical and health scienceschemistry.chemical_compoundPhosphatidylcholineSpectroscopy Fourier Transform InfraredMembrane fluiditypolycyclic compoundsComputer SimulationLipid bilayerPOPCRotational correlation time030304 developmental biology0303 health sciencesLiposomeMembranestechnology industry and agricultureSignal Processing Computer-Assisted0104 chemical sciencesCrystallographyCholesterolSpectrometry FluorescencechemistryLiposomesPhosphatidylcholinesAnisotropylipids (amino acids peptides and proteins)AlgorithmsBiophysical journal
researchProduct

On Sturmian Graphs

2007

AbstractIn this paper we define Sturmian graphs and we prove that all of them have a certain “counting” property. We show deep connections between this counting property and two conjectures, by Moser and by Zaremba, on the continued fraction expansion of real numbers. These graphs turn out to be the underlying graphs of compact directed acyclic word graphs of central Sturmian words. In order to prove this result, we give a characterization of the maximal repeats of central Sturmian words. We show also that, in analogy with the case of Sturmian words, these graphs converge to infinite ones.

Discrete mathematicsApplied MathematicsCDAWGsContinued fractionsSturmian wordSturmian wordsCharacterization (mathematics)RepeatsDirected acyclic graphCombinatoricsIndifference graphSturmian words CDAWGs Continued fractions RepeatsChordal graphComputer Science::Discrete MathematicsDiscrete Mathematics and CombinatoricsContinued fractionWord (group theory)Computer Science::Formal Languages and Automata TheoryReal numberMathematics
researchProduct

Verbal sets and cyclic coverings

2010

Abstract We consider groups G such that the set of all values of a fixed word w in G is covered by a finite set of cyclic subgroups. Fernandez-Alcober and Shumyatsky studied such groups in the case when w is the word [ x 1 , x 2 ] , and proved that in this case the corresponding verbal subgroup G ′ is either cyclic or finite. Answering a question asked by them, we show that this is far from being the general rule. However, we prove a weaker form of their result in the case when w is either a lower commutator word or a non-commutator word, showing that in the given hypothesis the verbal subgroup w ( G ) must be finite-by-cyclic. Even this weaker conclusion is not universally valid: it fails …

Discrete mathematicsCommutatorgroup wordAlgebra and Number TheorySubgroup coveringscommutatorComputer Science::Computation and Language (Computational Linguistics and Natural Language and Speech Processing)Central seriescoveringSet (abstract data type)Verbal subgroupsVerbal subgroupCharacteristic subgroupGroup theoryLower central seriesFinite setWord (group theory)Group theoryCyclic subgroupsMathematicsJournal of Algebra
researchProduct

When can association graphs admit a causal interpretation?

1994

We discuss essentially linear structures which are adequately represented by association graphs called covariance graphs and concentration graphs. These do not explicitly indicate a process by which data could be generated in a stepwise fashion. Therefore, on their own, they do not suggest a causal interpretation. By contrast, each directed acyclic graph describes such a process and may offer a causal interpretation whenever this process is in agreement with substantive knowledge about causation among the variables under study. We derive conditions and procedures to decide for any given covariance graph or concentration graph whether all their pairwise independencies can be implied by some …

Discrete mathematicsComputer sciencePairwise comparisonCausationCovarianceDirected acyclic graphUndirected graphAlgorithmGraph
researchProduct