Triazolopyridines. Part 11. Ylides derived from 2-Acylmethyltriazolopyridinium salts.

6533b823fe1ef96bd127ea51

RESEARCH PRODUCT

Triazolopyridines. Part 11. Ylides derived from 2-Acylmethyltriazolopyridinium salts.

B. Abarca M. R. Metni Enrique Pérez-carreño Gumos Jones Fatemeh Mojarrad R. Ballesteros Santiago García-granda

subject

Dimethyl acetylenedicarboxylate Bicyclic molecule Organic Chemistry Crystal structure Nuclear magnetic resonance spectroscopy Biochemistry Medicinal chemistry Adduct Ethyl propiolate chemistry.chemical_compound chemistry Drug Discovery X-ray crystallography Michael reaction

description

Abstract Ylides derived from 2-acylmethyltriazolopyridinium salts (2a) -(2c) react with methyl or ethyl propiolate and with dimethyl acetylenedicarboxylate to give ylides (3a)–(3e), (6) or (7). In some cases 1:2 adducts are formed, shown to be the novel ylides (8a)–(8d); an X-ray diffraction confirms structure (8a).

year	journal	country	edition	language
1991-01-01	Tetrahedron

https://doi.org/10.1016/s0040-4020(01)87139-8

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