Search results for "dUMP"
showing 10 items of 40 documents
Thymidylate synthases from Hymenolepis diminuta and regenerating rat liver: purification, properties, and inhibition by substrate and cofactor analog…
1995
Comparative studies of thymidylate synthases, isolated from the tapeworm, Hymenolepis diminuta, and regenerating liver of its host, rat, aimed at a possibility of specific inhibition of the helminthic enzyme, are presented. While similar in structure (dimers with monomer molecular masses of 33.7 kDa and 34.9 kDa, respectively) and parameters describing interactions with substrates and products, the tapeworm and rat enzymes differed in the dependences of reaction velocity on temperature (Arrhenius plots biphasic and linear, respectively). The tapeworm, compared with the host, enzyme was less sensitive to the competitive slow-binding inhibition by 5-fluoro-dUMP and its 2-thio congener, but eq…
Breaking the law? Varieties of social dumping in a pan- European labour market
2015
CERN-MEDICIS: A Review Since Commissioning in 2017
2021
The CERN-MEDICIS (MEDical Isotopes Collected from ISolde) facility has delivered its first radioactive ion beam at CERN (Switzerland) in December 2017 to support the research and development in nuclear medicine using non-conventional radionuclides. Since then, fourteen institutes, including CERN, have joined the collaboration to drive the scientific program of this unique installation and evaluate the needs of the community to improve the research in imaging, diagnostics, radiation therapy and personalized medicine. The facility has been built as an extension of the ISOLDE (Isotope Separator On Line DEvice) facility at CERN. Handling of open radioisotope sources is made possible thanks to i…
Application of DPSIR framework to analyze the groundwater pollution threats of municipal solid waste: Case study Médiouna Landfill, Morocco
2021
This study addresses the issue of groundwater resources quality affected by solid waste disposed of in the Médiouna dumping site. In this order, we applied the Driving forcePressureStateImpact Response model (DPSIR) model combined with external factors of SWOT analysis (Opportunities and Threats) to assess the environmental impact of waste from Médiouna landfill on groundwater. The analysis study revealed that the continuous demographic expansion and economic growth made solid waste a complex problem. The study highlights the urgent need for implementing new strategies and redesigning more effective, operational and realizable management projects to rehabilitate the Médiouna landfill. In ad…
High voltage conditioning of the electrostatic deflector of MARA
2016
Abstract MARA is a new recoil mass separator in the Accelerator Laboratory of University of Jyvaskyla (JYFL-ACCLAB) with a mass resolving power of 250 and an ion-optical configuration of QQQD E D M . In this paper the construction, control and conditioning of its electrostatic deflector are described. The deflector was designed for voltages up to 500 kV accross the gap, corresponding to a 3.6 MV/m field, to accomodate fusion reactions with inverse kinematics. Titanium electrodes with a beam dump opening in the anode are used. The conditioning procedure, which has been used repeatedly to take the deflector to 450 kV, is described, along with the safety systems and precautions that are in pla…
Impact of Global Economic Crisis on the European Welfare States
2013
The global economic crisis and the subsequent weaker growth are putting under pressure welfare states in the EU. This paper aims at discussing the effects of the crisis at the social level and at identifying whether the classic European welfare state models (Nordic, Continental, Anglo-Saxon and Mediterranean) are still valid in today’s economy. An answer will be tried using the mathematical tool of principal components analysis. The results will be observed in graphs where the states taken into consideration respect the classical welfare models or they regroup themselves into new circumstances’ adapted models. Even though the classical welfare models are generally still checked up with the …
Atomic physics of positronium with intense slow positron beams
2002
Abstract The theory of quantum electrodynamics has presented a complete calculation of the energy levels of positronium (Ps, e + e − ) up to the order R ∞ α 4 . The annihilation rates for para -Ps (1 1 S 0 ) and ortho -Ps (1 1 S 1 ) are completely known up to the order R ∞ α 5 and R ∞ α 6 , respectively. The present experimental uncertainty for spectroscopic results is 5–100 times larger than the theoretical uncertainty. For the annihilation rates the experimental situation is even worse. The theoretical predictions have presently reached a level of precision which is a challenge to experimentalists! The experimental uncertainty for the fine- and hyperfine transitions in the Ps atom is dete…
Instrumentation and optimization studies for a beam dump experiment (BDX) at MESA — DarkMESA
2020
Abstract At the Institute for Nuclear Physics in Mainz the new electron accelerator MESA will go into operation within the next years. The high-power beam dump of the P2 experiment is ideally suited for a parasitic dark sector experiment — DarkMESA. In the first stage 1,000 high density Cherenkov radiators from a previous experiment will be used. The experiment is studied with a simulation based on MadGraph and Geant4 . The simulation includes an optical photon study, where the response of possible calorimeter materials – PbF 2, BGO, the Pb glasses SF5, SF6 and SF57HTultra from Schott – was investigated. The simulation outcomes are compared with the results of prototypes tested at the Mainz…
Origin of atmospheric lead in Johannesburg, South Africa
2006
International audience; The origin of lead in the atmosphere of Johannesburg, South Africa was investigated on the basis of elemental and lead isotopic analyses of coals, mine dumps, gasoline, and about 30 epiphytic lichen samples. Lead predominantly comes from automotive exhausts in urban and suburban areas, as leaded antiknock additives were still in use in South Africa at the time of the study. Although dust emissions from the numerous mine-tailing dumps were expected to contribute significantly to the heavy metal budget, the southern townships that are surrounded by the dumps (such as Soweto and other historically Black residential areas) do not appear to be more than partially influenc…
Assessment of Gamma Dose Rate at Mine Waste Dump
2013
Abstract Exploitation of coal deposits in Upper Silesia is associated with production of large quantities of waste deposited at dumps. The tested samples from five dumps showed different radioactivity from each other. Radioactivity measurements made it possible to analyze the degree of risk with the factors specified by UNSCEAR such as radium equivalent activity Raeq, internal Ein and external Eex occupancy factor. There is a raised level of radiation in dumps as compared with outside dump areas. In the study area, however, there is no risk associated with elevated levels of radiation in relation to standards established by the Council of Ministers of the ionizing radiation dose limits.