Search results for "dalit"

showing 10 items of 1091 documents

Treatment options for leishmaniasis.

2021

Leishmaniasis is broadly classified into three types: cutaneous, mucocutaneous and visceral. The visceral form is most dangerous and can result in death. Although leishmaniasis is an ancient disease, its treatment is still challenging. Several drugs, differing in their cost, toxicity, treatment duration and emergence of drug resistance, are used for different types of leishmaniasis. To overcome these limitations, the search for newer drugs and other treatments continues. In this article, we discuss conventional drugs, other treatments, including newer options such as immunotherapy and immunochemotherapy, and future prospects for leishmaniasis treatment.

medicine.medical_specialtyHot Temperaturemedicine.medical_treatmentTreatment durationMucocutaneous zone610 MedizinAntiprotozoal AgentsDermatologyDiseaseDrug resistance610 Medical sciencesmedicineHumansLeishmaniasisbusiness.industryTreatment optionsLeishmaniasisImmunotherapymedicine.diseaseDermatologyCombined Modality TherapyPhotochemotherapyCryotherapyDrug Therapy CombinationImmunotherapybusinessClinical and experimental dermatologyReferences
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Multimodality 3-dimensional volumetric ultrasound in obstetrics and gynecology with an emphasis in HDlive technique.

2013

HDlive (high-definition live or real-time US), a new ultrasound software, combines a movable virtual adjustable light source in a software that calculates the proportion of light reflecting through surface structures, depending on light direction. The light source can be manually positioned to illuminate the desired area of interest. The ultrasound technician can control light intensity to create shadows that enhance image quality. HDlive is an innovation that will render even more realistic images of fetal anatomy and of gynecologic lesions. The full potential of this new technology is yet to be determined and deserves scientific evaluation.

medicine.medical_specialtyImage qualityMultimodal ImagingMultimodalitySoftwareLight sourceObstetrics and gynaecologyComputer SystemsPregnancyImage Interpretation Computer-AssistedmedicineHumansRadiology Nuclear Medicine and imagingComputer visionDiagnostic Techniques Obstetrical and GynecologicalUltrasonographybusiness.industryEmphasis (telecommunications)UltrasoundImage EnhancementObstetric Labor ComplicationsLight intensityFemaleRadiologyArtificial intelligencebusinessGenital Diseases FemaleSoftwareUltrasound quarterly
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Complex regional pain syndrome: An optimistic perspective.

2014

Complex regional pain syndrome (CRPS) presents with clinical symptoms that can no longer be explained by the initial trauma, including pain, sensory, motor, and trophic symptoms, and impairment of autonomic control of the limb. These symptoms spread distally and go beyond single nerve innervation territories. Typically, the symptoms change through the course of CRPS as a result of the varying pathophysiology. Diagnosis is made clinically after the rigorous elimination of other possible causes, and 3-phase bone scintigraphy can be a useful tool for confirming CRPS. In acute stages, inflammatory symptoms prevail and should be treated with anti-inflammatory agents (steroids), bisphosphonates, …

medicine.medical_specialtyImagery PsychotherapyImplosive TherapyPainMotor imageryOccupational TherapyNeuroplasticitymedicineHumansKetamineGlucocorticoidsPhysical Therapy ModalitiesAnalgesicsmedicine.diagnostic_testBone Density Conservation AgentsDiphosphonatesbusiness.industrySensory lossmedicine.diseaseComorbidityComplex regional pain syndromeBone scintigraphyAutonomic Nervous System DiseasesHyperalgesiaHyperalgesiaPhysical therapyKetamineNeurology (clinical)medicine.symptombusinessComplex Regional Pain Syndromesmedicine.drugNeurology
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Effects of balance and proprioceptive training on total hip and knee replacement rehabilitation: A systematic review and meta-analysis.

2017

Abstract Backgound Balance and proprioceptive deficits are frequently persistent after total joint replacement, limiting functionality and involving altered movement patterns and difficulties in walking and maintaining postural control among patients. Research question The goal of this systematic review was to evaluate the short- and mid-term effects of proprioceptive and balance training for patients undergoing total knee and hip replacement. Methods This is a systematic review of literature. MEDLINE, Embase, Cochrane Library, PEDro, and Scopus were the databases searched. The review included randomized clinical trials in which the experimental groups underwent a training aimed at improvin…

medicine.medical_specialtyKnee Jointmedicine.medical_treatmentArthroplasty Replacement HipBiophysicsKnee replacementWalkingCochrane LibraryHip replacement (animal)law.invention03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationRandomized controlled triallawPostural BalanceMedicineHumansOrthopedics and Sports MedicineArthroplasty Replacement KneePostural BalancePhysical Therapy ModalitiesBalance (ability)Rehabilitationbusiness.industryRehabilitation030229 sport sciencesProprioceptionMeta-analysisHip Jointbusiness030217 neurology & neurosurgeryGaitposture
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Surgical sphincter saving approach and topical nifedipine for chronic anal fissure with hypertonic internal anal sphincter

2020

PURPOSE The role of augmented internal anal sphincter (IAS) tone in the genesis of posterior chronic anal fissure (CAPF) is still unknown. Lateral internal sphincterotomy is the most employed surgical procedure, nevertheless it is burdened by high risk post-operative anal incontinence. The aim of our study is to evaluate results of sphincter saving procedure with post-operative pharmacological sphincterotomy for patients affected by CAPF with IAS hypertonia. Methods: We enrolled 30 patients, undergone fissurectomy and anoplasty with V-Y cutaneous flap advancement; all patients received topical administration of nifedipine 0.3% and lidocaine 1.5% ointment-based therapy before and for 15 days…

medicine.medical_specialtyLidocaineNifedipinemedicine.medical_treatmentAdministration TopicalAnal CanalSurgical FlapsInternal anal sphincterFissurectomyOintmentsMuscle HypertoniaNifedipineMuscle HypertoniamedicineHumansProspective StudiesAnesthetics LocalAnestheticsAnal fissureAnal fissure Anoplasty Fissurectomy Lidocaine Nifedipine Proctology Administration Topical Anal Canal Anesthetics Local Calcium Channel Blockers Chronic Disease Combined Modality Therapy Humans Lidocaine Muscle Hypertonia Ointments Prospective Studies Surgical Flaps Treatment Outcome Fissure in Ano Nifedipinebusiness.industryLidocaineAnal canalAnoplastymedicine.diseaseCalcium Channel BlockersCombined Modality TherapySurgerymedicine.anatomical_structureTreatment OutcomeTopicalLocalAdministrationChronic DiseaseHypertoniaSurgeryFissure in Anomedicine.symptomAnal fissureProctologyLateral internal sphincterotomybusinessmedicine.drug
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Translocation (10;11;22)(p14;q24;q12) Characterized by Fluorescence in Situ Hybridization in a Case of Ewing's Tumor

2001

It is well recognized that the identification by classic cytogenetics of t(11;22)(q24;q12) is a useful aid in the accurate diagnosis of Ewing's sarcoma and related tumors. This translocation induces the EWS/FLI-1 fusion transcript, which can be detected by reverse transcription-polymerase chain reaction. Recent studies have also used fluorescence in situ hybridization (FISH) to demonstrate the translocation. The authors coupled classic cytogenetics and FISH on tumor cells from the original specimen, the local recurrence, and the pulmonary metastasis as well as from the xenografted tumors in a case of extraosseous Ewing's sarcoma. FISH analysis not only confirmed the cytogenetic results but …

medicine.medical_specialtyLung NeoplasmsOncogene Proteins FusionChromosomes Human Pair 22Bone NeoplasmsChromosomal translocationSarcoma EwingBiologyTranslocation GeneticPathology and Forensic MedicineImmunoenzyme TechniquesFatal OutcomemedicineHumansChildMolecular BiologyIn Situ Hybridization FluorescenceLegmedicine.diagnostic_testChromosomes Human Pair 10Proto-Oncogene Protein c-fli-1Reverse Transcriptase Polymerase Chain ReactionChromosomes Human Pair 11CytogeneticsChromosomeEwing's tumorDNA NeoplasmSequence Analysis DNACell Biologymedicine.diseaseCombined Modality TherapyFusion transcriptKaryotypingCancer researchFemaleInterphaseSarcomaRNA-Binding Protein EWSTranscription FactorsFluorescence in situ hybridizationDiagnostic Molecular Pathology
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Oral vinorelbine in the treatment of non-small cell lung cancer: rationale and implications for patient management.

2007

Vinorelbine is an established treatment for advanced non-small cell lung cancer (NSCLC), both as a single agent and in combination chemotherapy. Recently, an oral form of this agent has been developed. Before accepting an established agent in a different administration form, rigorous testing is required to answer such questions as reliable bioavailability, continued safety and preservation of efficacy. In addition, an oral agent must provide patient convenience and acceptance, while being an economically sound approach. Oral vinorelbine was found to have acceptable and reliable pharmacokinetic profiles at clinically relevant dosage levels. Oral vinorelbine was found to have approximately 40…

medicine.medical_specialtyLung Neoplasmsmedicine.drug_classAdministration OralPharmacologyVinorelbineVinblastineRoute of administrationchemistry.chemical_compoundOral administrationCarcinoma Non-Small-Cell LungAntineoplastic Combined Chemotherapy ProtocolsMedicineAntiemeticHumansPharmacology (medical)Randomized Controlled Trials as Topicbusiness.industryCombination chemotherapyVinorelbineAntineoplastic Agents PhytogenicCombined Modality TherapyGemcitabineCarboplatinBioavailabilitySurgerychemistryOral vinorelbine small cell lung cancer.businessmedicine.drugDrugs
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Update in minimally invasive periorbital rejuvenation with a focus on platelet-rich plasma: A narrative review.

2020

Background The periorbital region is among the first areas to be affected by the process of aging, which is influenced by genetic and constitutional factors. As the region plays an important role in overall facial appearance, rejuvenation of the area has immense cosmetic benefit and various treatment modalities have been used to achieve the same. Aims This article reviews commonly used non-surgical and minimally invasive modalities for periorbital rejuvenation. Methods The literature research considered published journal articles (clinical trials or scientific reviews). Studies were identified by searching electronic databases (MEDLINE and PubMed) and reference lists of respective articles.…

medicine.medical_specialtyMEDLINEDermatologyCosmetic TechniquesPeriorbital rejuvenation030207 dermatology & venereal diseases03 medical and health sciencesBlood Transfusion Autologous0302 clinical medicineMedicineHumansRejuvenationRejuvenationModalitiesModality (human–computer interaction)business.industryPlatelet-Rich PlasmaDermatologySkin AgingClinical trialTreatment Outcome030220 oncology & carcinogenesisPlatelet-rich plasmaFaceNarrative reviewbusinessJournal of cosmetic dermatologyREFERENCES
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Management of the oral hemangiomas in infants and children : scoping review

2019

Background Pediatric oral hemangiomas are benign vascular tumors that can be seen from birth, particularly in females. Hemangiomas are most frequent located in the lips and usually regress spontaneously, thus they do not require any type of treatment in most cases. The present scoping review pretended to synthesize the most relevant and currently available information from the international dental literature published in the last 25 years, regarding the management of pediatric oral hemangiomas. Material and Methods An exhaustive literature search was performed in four electronic databases (PubMed, Embase, Google Scholar, and Cochrane). Initially, 241 related titles and abstracts were found.…

medicine.medical_specialtyMEDLINEReviewHemangioma03 medical and health sciences0302 clinical medicineSurgical removalmedicineHumansChildGeneral DentistryMouth neoplasmModalitiesOral Medicine and Pathologybusiness.industryGeneral surgeryInfant030206 dentistrymedicine.disease:CIENCIAS MÉDICAS [UNESCO]Vascular TumorsOtorhinolaryngologyData extractionUNESCO::CIENCIAS MÉDICASSurgeryMouth NeoplasmsDifferential diagnosisbusinessHemangioma
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Non‐invasive diagnostic techniques in pigmentary skin disorders and skin cancer

2021

Background Diagnosis of pigmentary skin disorders, pre-cancerous and cancerous skin diseases is traditionally relied on visual assessment. The most widely applied invasive diagnostic technique is the skin biopsy. There have been significant technological advances in non-invasive diagnostic methods for skin disorders. Objective The objective of this article is to discuss different non-invasive diagnostic modalities, used in the diagnosis of pigmentary skin disorders and cutaneous cancers. Methods Comprehensive literature search was performed to screen articles related to non-invasive diagnostic techniques in pigmentary skin disorders and cutaneous cancers. Articles published in journals inde…

medicine.medical_specialtyMicroscopy ConfocalSkin Neoplasmsmedicine.diagnostic_testbusiness.industryNon invasiveMagnetic resonance imagingDermatologymedicine.diseaseSensitivity and SpecificityDermatologyDiagnostic modalitiesClinical trialOptical coherence tomographyBiopsySkin biopsymedicineHumansSkin cancerbusinessSkinUltrasonographyJournal of Cosmetic Dermatology
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