Search results for "ddc:00"
showing 10 items of 31 documents
When are researchers willing to share their data? - Impacts of values and uncertainty on open data in academia.
2020
PLOS ONE 15(7), e0234172 (2020). doi:10.1371/journal.pone.0234172
Evidence for the mechanosensor function of filamin in tissue development
2016
AbstractCells integrate mechanical properties of their surroundings to form multicellular, three-dimensional tissues of appropriate size and spatial organisation. Actin cytoskeleton-linked proteins such as talin, vinculin and filamin function as mechanosensors in cells, but it has yet to be tested whether the mechanosensitivity is important for their function in intact tissues. Here we tested, how filamin mechanosensing contributes to oogenesis in Drosophila. Mutations that require more or less force to open the mechanosensor region demonstrate that filamin mechanosensitivity is important for the maturation of actin-rich ring canals that are essential for Drosophila egg development. The ope…
Most Diverse Near-Shortest Paths
2021
Computing the shortest path in a road network is a fundamental problem that has attracted lots of attention. However, in many real-world scenarios, determining solely the shortest path is not enough as users want to have additional, alternative ways of reaching their destination. In this paper, we investigate a novel variant of alternative routing, termed the k-Most Diverse Near-Shortest Paths (kMDNSP). In contrast to previous work, kMDNSP aims at maximizing the diversity of the recommended paths, while bounding their length based on a user-defined constraint. Our theoretical analysis proves the NP-hardness of the problem at hand. To compute an exact solution to kMDNSP, we present an algori…
Using On-Demand File Systems in HPC Environments
2019
In modern HPC systems, parallel (distributed) file systems are used to allow fast access from and to the storage infrastructure. However, I/O performance in large-scale HPC systems has failed to keep up with the increase in computational power. As a result, the I/O subsystem which also has to cope with a large number of demanding metadata operations is often the bottleneck of the entire HPC system. In some cases, even a single bad behaving application can be held responsible for slowing down the entire HPC system, disrupting other applications that use the same I/O subsystem. These kinds of situations are likely to become more frequent in the future with larger and more powerful HPC systems…
Realizing total reciprocity violation in the phase for photon scattering
2017
Scientific reports 7, 43114 (2017). doi:10.1038/srep43114
FlexibleSUSY -- A spectrum generator generator for supersymmetric models
2014
We introduce FlexibleSUSY, a Mathematica and C++ package, which generates a fast, precise C++ spectrum generator for any SUSY model specified by the user. The generated code is designed with both speed and modularity in mind, making it easy to adapt and extend with new features. The model is specified by supplying the superpotential, gauge structure and particle content in a SARAH model file; specific boundary conditions e.g. at the GUT, weak or intermediate scales are defined in a separate FlexibleSUSY model file. From these model files, FlexibleSUSY generates C++ code for self-energies, tadpole corrections, renormalization group equations (RGEs) and electroweak symmetry breaking (EWSB) co…
Dynamical twisted mass fermions with light quarks: simulation and analysis details
2008
In a recent paper [hep-lat/0701012] we presented precise lattice QCD results of our European Twisted Mass Collaboration (ETMC). They were obtained by employing two mass-degenerate flavours of twisted mass fermions at maximal twist. In the present paper we give details on our simulations and the computation of physical observables. In particular, we discuss the problem of tuning to maximal twist, the techniques we have used to compute correlators and error estimates. In addition, we provide more information on the algorithm used, the autocorrelation times and scale determination, the evaluation of disconnected contributions and the description of our data by means of chiral perturbation theo…
Restrictions on data-driven political micro-targeting in Germany
2017
The revitalisation of canvassing in recent elections is strongly related to campaigns´ growing possibilities for analysing voter data to gain knowledge about their constituents, identifying their most likely voters and serving up personalised messages through individual conversations. The research literature about political micro-targeting hardly ever focusses on campaigns in parliamentary democracies with strict data protection laws. Based on in-depth expert interviews we introduce a framework of constraints in strategic political communication and reveal several restrictions on the macro, meso and micro levels which hinder the implementation of sophisticated data strategies in Germany. We…
Overview of first Wendelstein 7-X high-performance operation
2019
Abstract The optimized superconducting stellarator device Wendelstein 7-X (with major radius , minor radius , and plasma volume) restarted operation after the assembly of a graphite heat shield and 10 inertially cooled island divertor modules. This paper reports on the results from the first high-performance plasma operation. Glow discharge conditioning and ECRH conditioning discharges in helium turned out to be important for density and edge radiation control. Plasma densities of with central electron temperatures were routinely achieved with hydrogen gas fueling, frequently terminated by a radiative collapse. In a first stage, plasma densities up to were reached with hydrogen pellet injec…
Open data from the first and second observing runs of advanced LIGO and advanced Virgo
2021
Abbot, Rich, et al. (Virgo and MAGIC Collaboration)