Search results for "death"
showing 10 items of 1744 documents
Targeting the mevalonate pathway for improved anticancer therapy.
2009
The mevalonate pathway is important for the generation of isoprene moieties thereby providing the basis for the biosynthesis of molecules required for maintaining membrane integrity, steroid production and cell respiration. Additionally, isoprene precursors are indispensable for the prenylation of regulatory proteins such as Ras and Ras-homologous (Rho) GTPases. These low molecular GTP-binding proteins play key roles in numerous signal transduction pathways stimulated upon activation of cell surface receptors by ligand binding. Thus, Ras/Rho proteins eventually regulate cell proliferation, tumor progression and cell death induced by anticancer therapeutics. Lipid modification of Ras/Rho pro…
Olive oil intake and risk of cardiovascular disease and mortality in the PREDIMED Study
2014
[Background] It is unknown whether individuals at high cardiovascular risk sustain a benefit in cardiovascular disease from increased olive oil consumption. The aim was to assess the association between total olive oil intake, its varieties (extra virgin and common olive oil) and the risk of cardiovascular disease and mortality in a Mediterranean population at high cardiovascular risk.
On pragmemes again: dealing with death
2010
Combined effect of sauna bathing and cardiorespiratory fitness on the risk of sudden cardiac deaths in Caucasian men : a long-term prospective cohort…
2018
Both cardiorespiratory fitness (CRF) and frequency of sauna bathing (FSB) are each strongly and independently associated with sudden cardiac death (SCD) risk. However, the combined effect of CRF and FSB on SCD risk has not been previously investigated. We evaluated the joint impact of CRF and FSB on the risk of SCD in the Kuopio Ischemic Heart Disease prospective cohort study of 2291 men aged 42–61 years at recruitment. Objectively measured CRF and self-reported sauna bathing habits were assessed at baseline. CRF was categorized as low and high (median cutoffs) and FSB as low and high (defined as ≤2 and 3–7 sessions/week respectively). Multivariable adjusted hazard ratios (HRs) with confide…
Psilocybin as an inducer of ego death and similar experiences of religious provenance
2016
The purpose of this chapter is to provide an overview of the impact of hallucinogenic psilocybin on religious-type emotionality related to ego disintegration. Psilocybin as a typical hallucinogen evokes alternations of visual perception (enhances a development of pseudo-hallucinations, phantom visual perception, or hypnagogic experiences). These visual phenomena may be inspiring and are claimed to enhance aesthetic appreciation. Additionally the hallucinogen induces transient impairment of cognitive functions and psychological regression comparable to the signs of ego blurring and dissociative phenomena. The psilocybin effects, initially euphoric, may become emotionally perceived as anxious…
Cytotoxic Effect of Eudesmanolides Isolated from Flowers of Tanacetum vulgare ssp. siculum
2012
WOS: 000306752700042
Sexybeibit ja kiva kuolo
2019
Obraz v "Zapiskah ohotnika" Ivana Turgeneva i "Zerkale morej" Džozefa Konrada
2015
"Antavat anteeksi ovenvieret" : Matjoi Plattosen kuolinriittikuvaukset siirtymäriittiteorian valossa
2019
Tässä tutkimuksessa tarkastellaan suistamolaiselta itkijältä Matjoi Plattoselta vuosina 1908−1920 tallennettuja kuolinrituaalien kuvauksia ja niihin liittyviä itkuvirsiä siirtymäriittiteorian avulla. Tutkimuksen aineiston Plattosen kanssa ovat tuottaneet Matti Kaisla, U. T. Sirelius ja A. O. Väisänen. Tutkimuksessa kiinnitetään huomiota erityisesti rituaalisen itkemisen merkitykseen kuolinrituaalien osana. Yksilön tai ryhmän sosiaalisen kategorisen muutoksen yleismaailmallisesti kolmeen vaiheeseen jakavan siirtymäriittiteorian kehitti etnologi Arnold van Gennep (1873−1957). Hän väitti, että rituaaliset seremoniat, jotka liittyvät ihmiselämän tärkeimpiin muutoksiin, eroavat toisistaan eri ku…
Datortomogrāfijas protokola pielietošana smadzeņu nāves apstiprināšanai
2020
Bakalaura darba tēma ir “Datortomogrāfijas protokola pielietošana smadzeņu nāves apstiprināšanā”. Attīstoties intensīvās terapijas un transplantoloģijas nozarēm, smadzeņu nāves diagnostikā nepieciešams papildus veikt izmeklējumus, kas nodrošina ātru un efektīvu rezultātu, veicot apstiprinājumu smadzeņu nāves diagnozei. Datortomogrāfijas angiogrāfija ir viens no tiem. Bakalaura darba izvirzītā hipotēze ir: datortomogrāfijas protokols smadzeņu nāves apstiprināšanai katrā slimnīcā ir atšķirīgs. Darba mērķis ir noskaidrot datortomogrāfijas protokola pielietošanu smadzeņu nāves apstiprināšanai 3 Latvijas slimnīcās. Pētniecības uzdevumi ir apkopot un analizēt literatūru par galvas smadzeņu anatom…