Search results for "death"

Palliative Care Professionals' Inner Life: Exploring the Relationships Among Awareness, Self-Care, and Compassion Satisfaction and Fatigue, Burnout, …

2015

Context. Professionals working in the landscape of death and dying frequently are exposed to existential issues, psychological challenges, and emotional distress associated with care at the end of life. Identifying factors that help professionals cope with frequent exposure to issues related to mortality could enhance palliative care providers' and patients' quality of life. Objectives. To improve our understanding of the factors associated with professionals' inner life, through the assessment of an adapted version of Kearney and Kearney's awareness model of self-care. The main assumptions of the study were that competence in coping with death and awareness would be positively related to c…

Panorama de la Calidad de Vida Laboral entre Trabajadores que Prestan Cuidados Paliativos en Brasil

2019

Resumo Este artigo tem por objetivo oferecer um primeiro diagnóstico sobre os níveis de qualidade de vida dos trabalhadores brasileiros que prestam cuidados paliativos. Foram aplicadas escalas de medidas de qualidade de vida profissional, en-frentamento ante a morte, autocuidado profissional e autoconsciência em 161 profissionais. As análises de dados incluíram estatísticas descritivas, comparação dos níveis em função de sexo, idade e outras características sociodemográficas, e estudo da relação entre as variáveis mencionadas. Foram encontrados níveis adequados tanto nas variáveis de proteção da qualidade de vida profissional como na qualidade de vida em si. As comparações em função de dado…

Lesions of Proximal Coronary Arteries

2009

Coronary artery disease (CAD) remains the leading cause of death in the Western world. Conventional coronary angiography (CCA) is the gold standard method for evaluation of the vascular lumen and provides excellent results in demonstrating stenotic lesions of CAD. However, it is an invasive procedure with a small risk of fatal events. Furthermore, CCA is a lumen-oriented technique that does not permit a direct visualization and evaluation of the coronary artery wall. The characterization of coronary plaques without a significant lumen narrowing is also not feasible with CCA. This information is relevant since the comparison of angiographic studies of coronary arteries performed before and a…

FERULIC ACID INHIBITS OXIDATE STRESS AND CELL DEATH INDUCED BY Ab OLIGOMERS: IMPROVED DELIVERY BY SOLID LIPID NANOPARTICLES.

2009

Oxidative stress and dysfunctional mitochondria are among the earliest events in AD, triggering neurodegeneration. The use of natural antioxidants could be a neuroprotective strategy for blocking cell death. Here, the antioxidant action of ferulic acid (FA) on different paths leading to degeneration of recombinant beta-amyloid peptide (rAbeta42) treated cells was investigated. Further, to improve its delivery, a novel drug delivery system (DDS) was used. Solid lipid nanoparticles (SLNs), empty or containing ferulic acid (FA-SNL), were developed as DDS. The resulting particles had small colloidal size and highly negative surface charge in water. Using neuroblastoma cells and rAbeta42 oligome…

Benefits of a support programme for family caregivers of patients at the end of life: A randomised controlled trial.

2020

This study aims to analyse the impact that a psychological intervention programme has on the emotional state of family caregivers of patients at the end of life. The study is longitudinal with two arms (control and experimental). Data was collected from 154 primary family caregivers of patients at the end of life as well as from their respective 154 care-recipients. The intervention programme has shown its effectiveness in reducing anxiety, emotional distress and burden in the family caregivers of end-of-life patients. A reduction of anxiety of patients whose family caregivers participated in the intervention was also observed.

The Review Power of the Supreme Court of the People’s Republic of China on Death Penalty Cases

2008

Toll-like receptors are part of the innate immune defense system of sponges (demospongiae: Porifera).

2006

During evolution and with the emergence of multicellular animals, the need arose to ward off foreign organisms that threaten the integrity of the animal body. Among many different receptors that participate in the recognition of microbial invaders, toll-like receptors (TLRs) play an essential role in mediating the innate immune response. After binding distinct microbial components, TLRs activate intracellular signaling cascades that result in an induced expression of diverse antimicrobial molecules. Because sponges (phylum Porifera) are filter feeders, they are abundantly exposed to microorganisms that represent a potential threat. Here, we describe the identification, cloning, and deduced …

Identity and War in Michael Ondaatje’s

2012

Abstract This paper addresses the issue of identity in relation to war through a close reading of Michael Ondaatje’s The English Patient. It investigates the connections between war and the construction of identity, focusing on aspects such as violence and death. In his novel Ondaatje uncovers private histories alongside the framing events of World War Two. Kip’s perception of war and his way of living through it suggest that the engagement on the world’s battlefield is riddled with inner conflicts separating people or bringing them together. In The English Patient what is at issue is the quest for a redefinition of the self: Hanna, Kirpal Singh and Almásy attempt to liberate the self throu…

Death and Transfiguration : The Late Kim Jong-il Aesthetic in North Korean Cultural Production

2016

This article assesses the official music scene in Pyongyang over a span of five dramatic years, surveying how changes in the field of music from 2009 to 2014 mirrored and in some cases presaged North Korean dynastic succession and political consolidation. The article draws upon a new abundance of performance data on North Korean musical groups, data which we argue is important but has largely been ignored or mischaracterized heretofore. The central crisis dealt with in the article is the decline and demise of Kim Jong-il, the architect of North Korea’s musical culture. In his final years, Kim Jong-il assented to the creation of a new leading musical group known as the Unhasu Orchestra, prom…

Low doses of paclitaxel potently induce apoptosis in human retinoblastoma Y79 cells by up-regulating E2F1.

2008

Paclitaxel (PTX) is an anticancer drug currently in phase II clinical trials. This study shows for the first time that low doses of PTX (5 nM) potently induce apoptosis in human retinoblastoma Y79 cells. The effect of PTX is accompanied by a potent induction of E2F1 which appears to play a critical role in the effects induced by PTX. PTX induced a dose- and time-dependent effect, with G2/M arrest, cyclines A, E and B1 accumulation and a marked modification in the status of Cdc2-cyclin B1 complex, the major player of the G2/M checkpoint. Apoptosis followed G2/M arrest. An early and prolonged increase in p53 expression with its stabilization by phosphorylation and acetylation and its nuclear …