Search results for "defect"

showing 10 items of 879 documents

Informe de la salud visual y ocular de los países que conforman la Red Epidemiológica Iberoamericana para la Salud Visual y Ocular (REISVO), 2009 y 2…

2015

A pesar de que se han hecho importantes progresos en el cuidado de la salud ocular, la prevalencia de la ceguera evitable sigue siendo inaceptablemente alta en muchos países y comunidades (OMS, 2009). La salud visual es un tema de la agenda política en algunos países; sin embargo, aún no se cuenta con un sistema de información que permita identificar la situación de morbilidad en salud visual en Iberoamérica, para poder priorizar y planificar la orientación de los servicios de atención en optometría y oftalmología. Para que existan planes de salud, deben establecerse líneas de base a través de un diagnóstico epidemiológico y de necesidades de la población; por esta razón, REISVO ha desarrol…

Infants discapacitats sensorialsSalud OcularSalut pública Cooperació internacionalCiencias MédicasUlls Malalties i defectesSalud visualGeneral Medicine
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An SPM-Enriched Marine Oil Supplement Shifted Microglia Polarization toward M2, Ameliorating Retinal Degeneration in rd10 Mice

2022

Retinitis pigmentosa (RP) is the most common inherited retinal dystrophy causing progressive vision loss. It is accompanied by chronic and sustained inflammation, including M1 microglia activation. This study evaluated the effect of an essential fatty acid (EFA) supplement containing specialized pro-resolving mediators (SPMs), on retinal degeneration and microglia activation in rd10 mice, a model of RP, as well as on LPS-stimulated BV2 cells. The EFA supplement was orally administered to mice from postnatal day (P)9 to P18. At P18, the electrical activity of the retina was examined by electroretinography (ERG) and innate behavior in response to light were measured. Retinal degeneration was …

InflammationPhysiologyInherited retinal dystrophiesClinical BiochemistryCell BiologyBiochemistrySpecialized pro-resolving mediatorsMedicaments Assaigs clínicsRetinitis pigmentosainherited retinal dystrophies; retinitis pigmentosa; inflammation; microglia; specialized pro-resolving mediators; oxidative stressOxidative stressUlls Malalties i defectesMicrogliaMolecular Biology
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Study of vacancy defects in PbSe and Pb1-xSnxSe by positron annihilation

1993

Abstract Positron lifetime measurements have been performed to study vacancy defects in vapour-liquid-solid (VLS) grown PbSe and Pb 1- x Sn x Se ( x = 0.07, 0.1, 0.3). Post-growth annealing under various vapour pressure conditions has been used to change the number of Pb vacancies, resulting in the determination of the specific positron trapping rate μ Pb v = (1.0±0.1)×10 14 s -1 . The sensitivity range of the positron annihilation method to the Pb vacancies was found to be 10 17 Pb ] 20 cm -3 . Positron lifetimes in perfect PbTe, PbSe and PbS crystals have been calculated. Moreover, we have predicted lifetimes of positrons trapped by vacancies. The calculated lifetimes in bulk and defects …

Inorganic ChemistryNuclear physicsPositronChemistryVapor pressureAnnealing (metallurgy)Vacancy defectMaterials ChemistryCondensed Matter PhysicsPositron trappingMolecular physicsPositron annihilationJournal of Crystal Growth
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Formation and migration of oxygen vacancies in La1−xSrxCo1−yFeyO3−δperovskites: insight from ab initio calculations and comparison with Ba1−xSrxCo1−y…

2013

The formation and migration of oxygen vacancies in the series of (La,Sr)(Co,Fe)O3−δ perovskites, which can be used as mixed conducting SOFC cathode materials and oxygen permeation membranes, are explored in detail by means of first principles density functional calculations. Structure distortions, charge redistributions and transition state energies during the oxygen ion migration are obtained and analyzed. Both the overall chemical composition and vacancy formation energy are found to have only a small impact on the migration barrier; it is rather the local cation configuration which affects the barrier. The electron charge transfer from the migrating O ion towards the transition metal ion…

Inorganic chemistryGeneral Physics and Astronomychemistry.chemical_elementOxygenElectric chargeCathodeIonlaw.inventionMembranechemistrylawAb initio quantum chemistry methodsChemical physicsVacancy defectPhysical and Theoretical ChemistryChemical compositionPhys. Chem. Chem. Phys.
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Reconstruction of full thickness scalp defects after tumour excision in elderly patients: our experience with Integra dermal regeneration template.

2010

Summary Background Scalp reconstruction after wide tumor excision is particularly challenging. Free tissue transfers, local flaps, or skin grafts can be used but present some disadvantages especially with old patients with local advanced cancers, systemic diseases and in patients with a prior history of recurring scalp skin cancers in which the risk of burying a recurring tumor with a flap is likely. The Authors expose their early experience with Integra ® dermal regeneration template for scalp reconstruction after scalp tumor excision. Methods Eight patients with primary or secondary scalp tumor underwent a first surgical procedure under local anaesthesia for tumor removal and Integra ® po…

Integra tumor scalp scalp defectmedicine.medical_specialtySkin NeoplasmsSettore MED/19 - Chirurgia PlasticaTumor excisionScalp reconstructionmedicineHumansMelanomaTumour excisionAged 80 and overSkin ArtificialScalpintegumentary systembusiness.industryRegeneration (biology)Chondroitin SulfatesSarcomaPlastic Surgery ProceduresSurgeryTumor recurrenceSkullmedicine.anatomical_structureScalpCarcinoma Squamous CellWounds and InjuriesSurgeryFull thicknessCollagenbusinessJournal of plastic, reconstructiveaesthetic surgery : JPRAS
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Perlecan Maintains microvessel integrity in vivo and modulates their formation in vitro

2012

Perlecan is a heparan sulfate proteoglycan assembled into the vascular basement membranes (BMs) during vasculogenesis. In the present study we have investigated vessel formation in mice, teratomas and embryoid bodies (EBs) in the absence of perlecan. We found that perlecan was dispensable for blood vessel formation and maturation until embryonic day (E) 12.5. At later stages of development 40% of mutant embryos showed dilated microvessels in brain and skin, which ruptured and led to severe bleedings. Surprisingly, teratomas derived from perlecan-null ES cells showed efficient contribution of perlecan-deficient endothelial cells to an apparently normal tumor vasculature. However, in perlecan…

IntegrinsAnatomy and PhysiologyGlycobiologylcsh:MedicineCardiovascularurologic and male genital diseasesCardiovascular SystemBiochemistryBiotecnologiaBasement MembraneMicePregnancyMolecular Cell BiologyMorphogenesisHistochemistrylcsh:ScienceSkinMice KnockoutPeripheral Vascular DiseasesExtracellular Matrix ProteinsNeovascularization PathologicTeratomaProteïnes de membranaBrainCell DifferentiationExtracellular MatrixConnective TissueCytochemistryMedicineFemaleFibroblast Growth Factor 2ProteoglycansResearch Articleendocrine systemMice 129 StrainCèl·lulesNeovascularization PhysiologicCell MigrationGrowth FactorsCell AdhesionAnimalsBirth DefectsBiologyExtracellular Matrix AdhesionsEmbryoid BodiesEmbryonic Stem Cellslcsh:RfungiProteinsExtracellular Matrix CompositionMice Inbred C57BLcarbohydrates (lipids)Cancer and OncologyMicrovesselsCardiovascular Anatomylcsh:QHeparan Sulfate ProteoglycansDevelopmental Biology
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Overview of the current status of familial hypercholesterolaemia care in over 60 countries - The EAS Familial Hypercholesterolaemia Studies Collabora…

2018

PubMed: 30270054

International CooperationMÉTODOS EPIDEMIOLÓGICOS030204 cardiovascular system & hematologyNationwide surveyGlobal HealthHealth Services AccessibilityDoenças Cardio e Cérebro-vascularesMOLECULAR-GENETICS0302 clinical medicineRisk FactorsPrevalenceCARDIOVASCULAR RISK-FACTORS030212 general & internal medicineCooperative BehaviorDEFECTIVE APOLIPOPROTEIN B-100GENERAL-POPULATIONeducation.field_of_studymedicine.diagnostic_testAnticholesteremic AgentsFamilial hypercholesterolaemia; FHSC; Primary dyslipidaemia; Anticholesteremic Agents; Biomarkers; Cholesterol LDL; Cooperative Behavior; Genetic Predisposition to Disease; Health Care Surveys; Health Services Accessibility; Healthcare Disparities; Humans; Hyperlipoproteinemia Type II; Phenotype; Predictive Value of Tests; Prevalence; Risk Factors; Treatment Outcome; Blood Component Removal; Global Health; International CooperationEAS Familial Hypercholesterolaemia Studies Collaboration3. Good healthPREVALENCECholesterolPhenotypeTreatment OutcomeBlood Component RemovalCORONARY-ARTERY-DISEASENATIONWIDE SURVEYCardiology and Cardiovascular MedicineFamilial hypercholesterolaemiamedicine.medical_specialtyCardiovascular risk factorsPopulationLDL-RECEPTOR1102 Cardiovascular Medicine And HaematologyLDLHyperlipoproteinemia Type II03 medical and health sciencesPredictive Value of TestsmedicineHumans:Medicine [Science]Genetic Predisposition to DiseasePrimary dyslipidaemiaHealthcare Disparitiesfhsc; familial hypercholesterolaemia; primary dyslipidaemiaeducationGenetic testingGovernmentPublic healthEAS Familial Hypercholesterolaemia Studies Collaboration (FHSC) InvestigatorsSAFEHEART REGISTRY1103 Clinical SciencesFHSCCholesterol LDLCardiovascular System & HematologyFamily medicineHealth Care Surveys3121 General medicine internal medicine and other clinical medicineCardiovascular System & CardiologyBusinessFOLLOW-UPBiomarkers
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IoT Contracts. An Empirical Research

2015

An empirical research on the contracts used in the Internet of Things to point out the most relevant contractual issues and the main dangers for customers of IoT products. In my opinion, in the IoT the notion itself of product changes and therefore there will be a revival of the product liability regime, which from now on will apply not only to hardware, but also to software and service.

Internet of things contracts contract law paternalism consumer law consumers product liability defective productsSettore IUS/01 - Diritto Privato
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Legal Certainty as a Tool for the Spread of the Internet of Things

2015

- Internet of Things Law (issues and main regulations) - Actors - Contract Law - Nest use case - Product liability - Privacy and data protection

Internet Internet of Things IoT IT law product liability defective products nest contracts supply chain privacy data protectionSettore IUS/01 - Diritto Privato
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Structural characterization of selective area growth GaN nanowires by non-destructive optical and electrical techniques

2015

The growth selectivity and structural quality of GaN nanowires obtained by plasma-assisted molecular beam epitaxy on pre-patterned GaN(0001) templates are investigated by means of non-destructive techniques. Optimum control over the nanowire arrangement and size requires a pitch between the mask apertures below twice the diffusion length of Ga atoms. Lower pitches, however, seem to slightly diminish the structural quality of the material, as revealed by the increase of the Raman peak linewidths. The photoluminescence spectra of the nanowires show a considerable presence of basal plane stacking faults, whose density increases for decreasing nanowire diameter. The capabilities of Kelvin probe…

Kelvin probe force microscopePhotoluminescenceMaterials scienceAcoustics and Ultrasonicsbusiness.industryNanowireNanotechnologyCondensed Matter PhysicsEpitaxyCrystallographic defectSurfaces Coatings and FilmsElectronic Optical and Magnetic Materialssymbols.namesakeMicroscopysymbolsOptoelectronicsbusinessRaman spectroscopyMolecular beam epitaxyJournal of Physics D: Applied Physics
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