Search results for "derivati"

Comparison of various liquid chromatographic methods for the analysis of avermectin residues in citrus fruits.

2001

Abstract Various liquid chromatographic (LC) techniques for analyzing avermectin (Abamectin) were compared after extraction of residues from citrus fruit samples by matrix solid-phase dispersion (MSPD). LC with UV and fluorescence detection were used as also was LC coupled to the mass spectrometer by an electrospray interface. The results obtained by the three methods were compared in terms of sensitivity and selectivity. The combination of MSPD extraction and LC with fluorescence detection have made it possible to quantify 0.5 μg kg −1 of Abamectin in 0.5 g of orange sample, with an overall average recovery of 94%. The procedure provides a simple and sensitive method for monitoring Abamect…

Enantiomerization of an inherently chiral resorcarene derivative: determination of the interconversion barrier by computer simulation of the dynamic …

2001

Abstract The inherently chiral tetrabenzoxazine resorcarene derivative 1 shows characteristic plateau-formation during enantioselective HPLC separation on the chiral stationary phase Chiralpak AD. By computer assisted peak form analysis of the elution profiles, obtained from temperature dependent dynamic HPLC (DHPLC) experiments, with ChromWin, the enantiomerization barrier Δ G # (298 K)=92±2 kJ mol −1 and the activation parameters Δ H # =53.0±1.8 kJ mol −1 and Δ S # =−131±14 J (K mol) −1 were determined.

Derivatives of Erythropoietin That Are Tissue Protective But Not Erythropoietic

2004

Erythropoietin (EPO) is both hematopoietic and tissue protective, putatively through interaction with different receptors. We generated receptor subtype–selective ligands allowing the separation of EPO's bioactivities at the cellular level and in animals. Carbamylated EPO (CEPO) or certain EPO mutants did not bind to the classical EPO receptor (EPOR) and did not show any hematopoietic activity in human cell signaling assays or upon chronic dosing in different animal species. Nevertheless, CEPO and various nonhematopoietic mutants were cytoprotective in vitro and conferred neuroprotection against stroke, spinal cord compression, diabetic neuropathy, and experimental autoimmune encephalomyeli…

Deterministic and Random Vibration of Linear Systems with Singular Parameter Matrices and Fractional Derivative Terms

2021

Both time- and frequency-domain solution techniques are developed for determining the response of linear multi-degree-of-freedom systems exhibiting singular parameter matrices and endowed with derivative terms of noninteger orders modeled as rational numbers. This is done based on the Moore-Penrose matrix inverse theory, in conjunction with a state variable formulation and with a complex modal analysis treatment. It is worth noting that, for the class of systems considered herein, this treatment also yields decoupled governing equations, thus facilitating further their numerical solution. Next, a generalization of the standard frequency-domain input-output (excitation-response) relationship…

Finite-Difference Time-Domain Simulation of Tower and Grounding Subjected to Lightning

2015

In this paper the behavior of a tower and its grounding system, subjected to a lightning, is faced. Finite difference time domain (FDTD) method has been chosen in order to study the non-linear time domain behavior of the system. The electromagnetic problem has been described by using two type of first order time derivative equations: Maxwell's equations and Telegraph equations. Aim of this work is to evaluate the possibility of a flashover between tower and power line, by considering different cases of study.

Innovative modeling of tuned liquid column damper controlled structures

2016

In this paper a different formulation for the response of structural systems controlled by Tuned Liquid Column Damper (TLCD) devices is developed, based on the mathematical tool of fractional calculus. Although the increasing use of these devices for structural vibration control, it has been demonstrated that existing model may lead to inaccurate prediction of liquid motion, thus reflecting in a possible imprecise description of the structural response. For this reason the recently proposed fractional formulation introduced to model liquid displacements in TLCD devices, is here extended to deal with TLCD controlled structures under base excitations. As demonstrated through an extensive expe…

A Robustness Approach to Reliability

2012

Reliability of products is here regarded with respect to failure avoidance rather than probability of failure. To avoid failures, we emphasize variation and suggest some powerful tools for handling failures due to variation. Thus, instead of technical calculation of probabilities from data that usually are too weak for correct results, we emphasize the statistical thinking that puts the designers focus on the critical product functions. Making the design insensitive to unavoidable variation is called robust design and is handled by (i) identification and classification of variation, (ii) design of experiments to find robust solutions, and (iii) statistically based estimations of proper safe…

Photo-induced fluorescence of magnesium derivatives of tetracycline antibiotics in wastewater samples

2009

Abstract An analytical strategy, for the determination of tetracyclines (TCs), based on a HPLC system coupled with a photo-reactor followed by post-column derivatization was developed. Higher fluorescence emission after coupling the resulting photo-fragments with magnesium ions was observed for the determination of minocycline (MC), epitetracycline (ETC), tetracycline (TC) and doxycycline (DC). The manifold included a HPLC system with a photo-reactor (PTFE tubing helically coiled around a low-pressure mercury lamp), a mixing T-piece and a fluorescence detector. The derivatization reagent was delivered at 0.5 mL min −1 by a pump. After HPLC separation using a gradient system with a mobile ph…

2018

Reactivity is an important parameter when considering the chemical modification or dissolution of cellulose. Different pretreatment methods affect cellulose reactivity by decreasing its degree of polymerization (DP) and crystallinity. In this study, the molar mass of cellulose was decreased via enzymatic pretreatment. Three commercial endoglucanase-rich products were tested. The target was to reduce the viscosity of the pulp to below 200 mL/g and, thus, increase the reactivity of the cellulose. For comparison, cellulose was also pretreated with ozone, and the effects of each pretreatment method on crystallinity and monosaccharide composition of the resulting pulps were investigated. Both en…

Analysis of Trace Pharmaceuticals and Related Compounds in Municipal Wastewaters by Preconcentration, Chromatography, Derivatization, and Separation …

2014

A significant portion of pharmaceuticals and other organic chemicals consumed by people and animals are released into municipal wastewater treatment plants. Most of them are degraded during the wastewater treatment processes, but some of them degrade only partially and may be widely transported and dispersed into the aquatic environment. This is why efficient and fast analytical methods are needed for detection of organic compounds in wastewaters at trace levels. Because wastewaters often consist of complex matrices and high-molecular mass materials, e.g., lignocellulosic biomass, which may bring challenges to the sample preparation procedures, efficient pre-concentration methods such as so…