Search results for "developmental"
showing 10 items of 19870 documents
Un 'sujet qui fâche' : l'évaluation des enseignants en France, entre défense statutaire, injonction au professionnalisme et autonomie professionnelle
2017
International audience; Cet article analyse les projets de réforme de l’évaluation des enseignants en France depuis la fin des années 1990 ainsi que les réactions, notamment syndicales, qu’ils ont suscitées. Cette évaluation est considérée comme un analyseur privilégié pour étudier les réactions des enseignants au développement de nouvelles politiques de reddition de comptes. A partir de méthodes qualitatives (entretiens, analyse de dépêches de presse et de corpus de documents), il étudie plus spécifiquement les systèmes de négociation des différents projets de réforme d’une évaluation régulièrement contestée mais jamais réformée au moment où nous terminons cet article. Adoptant une perspec…
Safety of Tyrosine Kinase Inhibitors in Patients With Differentiated Thyroid Cancer: Real-World Use of Lenvatinib and Sorafenib in Korea
2019
Background: Thyroid cancer has become the most common cancer in Korea. Generally, thyroid cancer patients have a good prognosis; however, 15–20% of patients experience recurrence or distant metastasis or are refractory to standard treatment. We assessed the safety of sorafenib and lenvatinib in patients with advanced or metastatic radioactive iodine-refractory differentiated thyroid cancers (DTC) consecutively treated at a tertiary center in South Korea.Methods: We retrospectively reviewed the charts of all consecutive patients with DTC treated during ≥6 months with lenvatinib (February 2016–April 2018) and sorafenib (January 2014–April 2018) at Gangnam Severance Hospital. Patients were tre…
Safety and immunogenicity of the PRAME cancer immunotherapeutic in metastatic melanoma: results of a phase I dose escalation study
2016
Purpose The PRAME tumour antigen is expressed in several tumour types but in few normal adult tissues. A dose-escalation phase I/II study (NCT01149343) assessed the safety, immunogenicity and clinical activity of the PRAME immunotherapeutic (recombinant PRAME protein (recPRAME) with the AS15 immunostimulant) in patients with advanced melanoma. Here, we report the phase I dose-escalation study segment. Patients and methods Patients with stage IV PRAME-positive melanoma were enrolled to 3 consecutive cohorts to receive up to 24 intramuscular injections of the PRAME immunotherapeutic. The RecPRAME dose was 20, 100 or 500 µg in cohorts 1, 2 and 3, respectively, with a fixed dose of AS15. Advers…
Why Did They Leave School? A Self Determination Theory Perspective into Narratives of Finnish Early School Leavers
2021
The present study aims to provide insights into the experiences of early school leavers within the Finnish context. We conducted a narrative inquiry among eleven early school leavers who were in prison when they were interviewed. Self Determination Theory (SDT), more specifically the concept of frustration of the three basic psychological needs of competence, relatedness and autonomy, and the tendency of people to move towards more supporting environments, was used as an interpretative tool, along with contextual information. We identified three pathways out of school, differing in the locus of need thwarting circumstances and the availability of access to transfer into a more satisfying en…
Autism spectrum disorder and schizophrenia – similarities between the two disorders with a case report of a patient with dual diagnosis
2023
This paper presents the genetic, molecular and neuroanatomical similarities between autism spectrum disorder (ASD) and schizophrenia using the case report of a 34-year-old female patient with a previous diagnosis of schizophrenia as an example. As a result of repeat hospitalization, expanded history, psychological testing and verification of persistent symptoms of psychopathology, a cooccurring diagnosis of autism spectrum disorder was made.
Common variants at VRK2 and TCF4 conferring risk of schizophrenia
2011
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field. Common sequence variants have recently joined rare structural polymorphisms as genetic factors with strong evidence for association with schizophrenia. Here we extend our previous genome-wide association study and meta-analysis (totalling 7 946 cases and 19 036 controls) by examining an expanded set of variants using an enlarged follow-up sample (up to 10 260 cases and 23 500 controls). In addition to previously reported alleles in the major histocompatibility complex region, near neurogranin (NRGN) and in an intron of transcription factor 4 (TCF4), we find two novel variants show…
Unique Problems Require Unique Solutions—Models and Problems of Linking School Effectiveness and School Improvement
2022
The article aims to outline the proposals for linking school effectiveness research and school improvement that are currently relevant in international discussion and to ask how they deal with the ‘technology deficit’ at the level of model improvement. We will first show the difference between school improvement and school effectiveness. Then, we outline areas showing basic problems associated with linking school effectiveness and school improvement. After that, we present a summary of two relevant models for linking school effectiveness research and school improvement—Comprehensive Framework of Effective School Improvement and Dynamic Model of Educational Effectiveness&md…
Enhancing the user authentication process with colour memory cues
2022
The authentication process is the first line of defence against potential impostors, and therefore is an important concern when protecting personal and organisational data. Although there are many options to authenticate digital users, passwords remain the most common authentication mechanism. However, with password numbers increasing, many users struggle with remembering multiple passwords, which affects their security behaviour. Previous researchers and practitioners have attempted to suggest ways to improve password memorability and security simultaneously. We introduce novel approach that utilises colour as a memory cue to increase password memorability and security. A longitudinal stud…
Emotional Profile and Intellectual Functioning
2015
Insufficient literature has been produced addressing children with borderline intellectual functioning (BIF) and gifted intellectual functioning (GIF). The goal of this work is to compare levels of self-esteem, depression, anxiety at school, and insecurity among children with BIF and GIF, and a control group of average intellectual functioning (AIF). There were participants of 104 children (fourth grade of primary school). Analyses revealed that children with BIF showed a lower level of self-esteem and higher levels of depression and school anxiety. Moreover, our findings highlight the co-occurrence of school anxiety, depressed mood, and insecurity among the BIF and AIF groups. One of the …
Self-esteem and intentions mediate perceived fitness with physical activity in Finnish adolescents with long-term illness or disabilities
2014
Background: The International Classification of Functioning, Disability and Health (ICF) is recognised as the common language in disability research. However, personal factors in the ICF are not explicitly coded because of cultural differences that influence physical activity (PA) participation. The ICF suggests using fitness as a personal factor, as well as other psychological assets. Intentions may serve as such psychological assets and studies on the antecedents to intentions which prompts PA behaviours is lacking in adolescent long term illness or disability (LTID) populations. Objective: The purpose of this study was to report how ICF personal factors can influence participation in PA.…