Search results for "device"

Solid-state-biased coherent detection of ultra-broadband terahertz pulses

2017

Significant progress in nonlinear and ultrafast optics has recently opened new and exciting opportunities for terahertz (THz) science and technology, which require the development of reliable THz sources, detectors, and supporting devices. In this work, we demonstrate the first solid-state technique for the coherent detection of ultra-broadband THz pulses (0.1-10 THz), relying on the electric-field-induced second-harmonic generation in a thin layer of ultraviolet fused silica. The proposed CMOS-compatible devices, which can be realized with standard microfabrication techniques, allow us to perform ultra-broadband detection with a high dynamic range by employing probe laser powers and bias v…

An intraoral drug delivery device for long term therapies: application in Alzheimer’s disease

2009

GENERATION OF ENTANGLED STATES OF TWO DISTANT CAVITY MODES VIA JOSEPHSON JUNCTION BASED DEVICES

2007

We present a simple scheme for the preparation of entangled states of the e.m. modes of two spatially separated microwave cavities exploiting their interaction with two superconducting SQUID rings embedded within them. The scheme requires that the two SQUID qubits are initially prepared in an entangled state and the possibility of controlling both the coupling strengths and the interaction times. We also briefly discuss the importance of such a theoretical scheme in view of possible applications in the context of quantum computing and its experimental feasibility.

A prototypal architecture of a IEEE 21451 network for smart grid applications based on power line communications

2015

This paper deals with the development of reliable measurement and communication devices and systems and their integration on a prototypal network architecture for smart grid applications, based on the use of narrowband power line communications (PLCs). The proposed solution is presented and discussed in the framework of the ISO/IEC/IEEE 21451 family of Standards. Currently, PLCs are not properly addressed by the aforesaid Standards; on the other hand, by including such issue, their guidelines could represent a common platform for the integration and interoperability of the proposed systems and devices. This would allow to exploit the benefits of the IEEE 21451 approach also for PLC-based sm…

Characterization of MEMS accelerometer self-noise by means of PSD and Allan Variance analysis

2017

In this paper, we have studied the sources of error of a low-cost 3-axis MEMS accelerometer by means of Power Spectral Density and Allan Variance techniques. These techniques were applied to the signals acquired from ten identical devices to characterize the variability of the sensor produced by the same manufacturer. Our analysis showed as identically produced accelerometer have somehow variable behavior in particular at low frequency. It is therefore of paramount importance before their use in Inertial Navigation or Earthquakes Monitoring System, a complete characterization of each single sensors.

Homodyne Solid-State Biased Coherent Detection of Ultra-Broadband Terahertz Pulses with Static Electric Fields.

2021

We present an innovative implementation of the solid-state-biased coherent detection (SSBCD) technique, which we have recently introduced for the reconstruction of both amplitude and phase of ultra-broadband terahertz pulses. In our previous works, the SSBCD method has been operated via a heterodyne scheme, which involves demanding square-wave voltage amplifiers, phase-locked to the THz pulse train, as well as an electronic circuit for the demodulation of the readout signal. Here, we demonstrate that the SSBCD technique can be operated via a very simple homodyne scheme, exploiting plain static bias voltages. We show that the homodyne SSBCD signal turns into a bipolar transient when the stat…

Pathways of Innovation: The I-District Effect Revisited

2018

The I-district effect establishes the existence of dynamic efficiency in Marshallian industrial districts in the form of a positive innovative differential comparing to the average of the economy. The hypothesis has been empirically validated for the case of technological innovation using patent indicators. Empirical research has assumed that all types of patentable figures (utility models, national patents, EPO, WIPO) have the same weight regardless of its actual or expected market value, which may be questionable given the differences in coverage, protection and cost of each figure. In this article, we question the existence of the I-district effect when each patent is weighted by its exp…

Patient perspectives in the management of asthma: improving patient outcomes through critical selection of treatment options

2010

Asthma is a chronic inflammatory disorder of the airways that requires long-term treatment, the goal of which is to control clinical symptoms for extended periods with the least possible amount of drugs. International guidelines recommend the addition of an inhaled long-acting beta2-agonist (LABA) to a low- to medium-dose inhaled corticosteroid (ICS) when low doses of ICS fail to control asthma symptoms. The fixed combined administration of ICS/LABA improves patient compliance, reducing the risk of therapy discontinuation. The relative deposition pattern of the inhaled drug to the target site is the result of a complex interaction between the device used, the aerosol formulation and the pat…

Biosensor Analysis of β2-Glycoprotein I–Reactive Autoantibodies: Evidence for Isotype-Specific Binding and Differentiation of Pathogenic from Infecti…

2007

Abstract Background: For the laboratory diagnosis of the antiphospholipid syndrome (APS) we developed a biosensor with the ability to distinguish between disease-relevant anti-β2-glycoprotein I (β2GPI) autoantibodies (anti-β2GPI) and pathogen-specific β2GPI cross-reactive antibodies that occur transiently during infections. Methods: We used a surface plasmon resonance (SPR) biosensor device. For the detection of anti-β2GPI in serum samples, affinity-purified human β2GPI was covalently attached to a functionalized n-alkanethiol self-assembling monolayer on the biosensor chip. After verifying the specificity of the biosensor system with a panel of monoclonal antibodies to β2GPI, we analyzed s…

Functionalization of Graphene with Molecules and/or Nanoparticles for Advanced Applications

2019

Graphene is considered the material of the third millennium, due to its extraordinary electronic and mechanical properties, and due to the possibility to modulate its conductivity, flexibility, elasticity, transparency, and biocompatibility by bottom-up approach. The possibility to gather the proper- ties of graphene and graphene oxide with those of functional moieties or nanoparticles is herein reviewed. The synthetic approaches proposed, either covalent or noncovalent, are aimed to tune appropriately graphene’s properties for the realization of materials for advanced uses, such as bio- medical applications, sensors, catalysis, and energy devices. In particular, methods based on covalent l…