Search results for "device"
showing 10 items of 1286 documents
In vitro models for the prediction of in vivo performance of oral dosage forms: Recent progress from partnership through the IMI OrBiTo collaboration
2019
The availability of in vitro tools that are constructed on the basis of a detailed knowledge of key aspects of gastrointestinal (GI) physiology and their impact on formulation performance and subsequent drug release behaviour is fundamental to the success and efficiency of oral drug product development. Over the last six years, the development and optimization of improved, biorelevant in vitro tools has been a cornerstone of the IMI OrBiTo (Oral Biopharmaceutics Tools) project. By bringing together key industry and academic partners, and by linking tool development and optimization to human studies to understand behaviour at the formulation/GI tract interface, the collaboration has enabled …
Productive Efficiency and Territorial Externalities in Small and Medium-Sized Industrial Firms: A Dynamic Analysis of the District Effect
2012
A series of works have analysed differential behaviour in terms of productive efficiency between companies inside a hypothetical industrial district and those outside the district. This objective has been addressed using measures of technical efficiency. The results obtained provide valuable information for quantifying the district effect at a given moment in time. However, constant changes in the market and business behaviour mean that it is worthwhile studying the business district effect from a dynamic point of view. In this study, we provide this new vision through the use of Malmquist productivity indices. This methodology enables us to analyse possible differential evolutions by compa…
Smart Cooling System for Milk Transportation in Rural Areas
2021
In the dairy industry, road milk tankers transport milk from one location to another. The milk inside the tanker needs to be kept between 3–5 °C to ensure that the quality of milk is always preserved. The tanker needs to be kept running at all time with the case of sufficient energy being continuously supplied to the cooling unit. The source of energy normally used for this application is a typical generator which needs fuel to operate. This is expensive and is not environmentally friendly. To address this problem, generator as a source of energy needs to be replaced by solar energy to lower the costs associated with cooling of the tanker. In this research a small scale solar powered intell…
Remote, web-based laboratory for Programmable Logic Devices
2009
Abstract This work proposes a web-based laboratory for remotely testing FPGA programs on an evaluation board. Using a web browser, the user can download a device configuration file (previously generated with the FPGA commercial tool) and test it in a real FPGA board located in a remote laboratory at the University facilities. The user can control inputs and check outputs’ state. This preliminary study tries to evaluate the possibilities that can be offered to the user, and the restrictions that might apply. Additionally, it describes the proposed infrastructure (hardware and software) needed to successfully deal with all the interesting features that a remote lab system for programmable log…
Exposed Subcutaneous Implantable Devices
2015
Background: Implantable venous and electrical devices are prone to exposure and infection. Indications for management are controversial, but—especially if infected—exposed devices are often removed and an additional operation is needed to replace the device, causing a delay in chemotherapy and prolonging healing time. We present our protocol for device salvage, on which limited literature is available. Methods: Between 2007 and 2013, 17 patients were treated (12 venous access ports, 3 cardiac pacemakers, and 2 subcutaneous neural stimulators). Most patients were operated within 7 days from exposure. All patients received only a single perioperative dose of prophylactic antibiotic. In cases …
A new road to improve vitamin D and balance through Taopatch® and proprioceptive protocol in Multiple Sclerosis patients
2022
: In multiple sclerosis patients (MS), symptoms such as fatigue, lack of physical energy, spasticity, motor coordination disorders, tremors, dizziness and postural instability are most common. Cattaneo et al. (2007) studied the effects of stability training on MS patients, describing its efficacy in reducing all risks, by improving stability, and strength. The present study aimed to confirm our 2021 results on MS patients, combining the Taopatch® device with a proprioceptive rehabilitation protocol (PRP) targeting strength, balance, and biochemical parameters including vitamin D levels. Twenty MS patients, 8 males and 12 females, volunteered in the study. A KERN MAP Version 1.2 08/2012, Han…
Can Interactive Mediation Tools Bridge the Identity Gap Between the Public and the Art Museum?
2015
International audience; Consumer behaviour in the field of art museums appears to be influenced both by the identity of the public and the art museum and by the context. It is a matter not of changing museum content, but of bringing its identity closer to that of the public in order to promote access to art. The authors first present the theoretical and conceptual framework for their research and then suggest a qualitative methodological approach to addressing the issues described in the results.; La conducta del consumidor en los museos de arte parece estar influenciada tanto por la identidad del público y del museo como por el contexto. No se trata de cambiar el contenido del museo, pero …
Pterostilbene-induced tumor cytotoxicity: a lysosomal membrane permeabilization-dependent mechanism.
2012
The phenolic phytoalexin resveratrol is well known for its health-promoting and anticancer properties. Its potential benefits are, however, limited due to its low bioavailability. Pterostilbene, a natural dimethoxylated analog of resveratrol, presents higher anticancer activity than resveratrol. The mechanisms by which this polyphenol acts against cancer cells are, however, unclear. Here, we show that pterostilbene effectively inhibits cancer cell growth and stimulates apoptosis and autophagosome accumulation in cancer cells of various origins. However, these mechanisms are not determinant in cell demise. Pterostilbene promotes cancer cell death via a mechanism involving lysosomal membrane …
Helmet continuous positive airway pressure and prone positioning: A proposal for an early management of COVID-19 patients
2020
In late December 2019, clusters of patients with interstitial pneumonia of unknown cause were reported by some local health facilities in Wuhan (China). The Chinese Centre for Disease Control conducted an epidemiologic and etiologic investigation, leading to the identification of a novel coronavirus (SARS-CoV-2).1, 2 On March 11th, the World Health Organization (WHO) declared the novel coronavirus disease (COVID-19) a pandemic. In the area of Wuhan, COVID-19 mainly affected male patients (around 60%), with a median age of about 50 years; 40% of patients developed Acute Respiratory Distress Syndrome (ARDS) 5% requiring intensive care. The mortality rate was around 2%.3, 4 However, Grasselli …
Does the frequency of switching inhalers represent a predictive factor of exacerbation in asthma?
2020
Objective: Management of asthma includes monitoring of inhaler technique and level of adherence to treatment. Both factors could be influenced by high frequency of switching inhaler devices. We explored whether switching inhalers is an independent predictive factor of exacerbations. Methods: Data were collected from 2015 to 2017 from the outpatient clinic of asthma at the University of Palermo, Italy. This observational study consisted of two phases: Phase 1 included subjects of at least three visits in the previous year who reported the frequency of inhalers switched; Phase 2 included subjects of at least two visits during the second year, and the rate of switches and exacerbations was rec…