Search results for "diagnosis"

showing 10 items of 2212 documents

Guideline-based survey of outpatient COPD management by pulmonary specialists in Germany

2012

Thomas Glaab1,2, Claus Vogelmeier3, Andreas Hellmann4, Roland Buhl11Department of Respiratory Diseases III, Medical Center of the Johannes Gutenberg-University, Mainz, 2Medical Affairs Germany, Respiratory Medicine, Boehringer Ingelheim Pharma GmbH and Co, KG, Ingelheim, 3Department of Respiratory Diseases, University Hospitals of Giessen and Marburg, Marburg, 4Federal Association of Pneumologists, Augsburg, GermanyBackground: Little is known about the role of guidelines for the practical management of chronic obstructive pulmonary disease (COPD) by office-based pulmonary specialists. The aim of this study was to assess their outpatient management in relation to current guideline recommenda…

AdultMaleSpirometryHealth Knowledge Attitudes Practicemedicine.medical_specialtyChronic bronchitisAttitude of Health Personneldiagnosismedicine.medical_treatmentInternational Journal of Chronic Obstructive Pulmonary DiseasePulmonary Disease Chronic ObstructivePatient Education as TopicAmbulatory careRisk FactorsGermanySurveys and QuestionnairesHealth careAmbulatory CaremedicineHumanssurveyPulmonary rehabilitationGOLDPractice Patterns Physicians'Referral and ConsultationOriginal ResearchtherapyCOPDEvidence-Based Medicinemedicine.diagnostic_testbusiness.industryGeneral MedicineGuidelineMiddle Agedmedicine.diseasepulmonary rehabilitationclinical outcomesObstructive lung diseaseRespiratory Function TestsBenchmarkingCross-Sectional StudiesHealth Care SurveysFamily medicinePractice Guidelines as TopicFemaleGuideline AdherencebusinessInternational Journal of Chronic Obstructive Pulmonary Disease
researchProduct

An ensemble analysis of electromyographic activity during whole body pointing with the use of support vector machines.

2011

Import JabRef | WosArea Life Sciences and Biomedicine - Other Topics; International audience; We explored the use of support vector machines (SVM) in order to analyze the ensemble activities of 24 postural and focal muscles recorded during a whole body pointing task. Because of the large number of variables involved in motor control studies, such multivariate methods have much to offer over the standard univariate techniques that are currently employed in the field to detect modifications. The SVM was used to uncover the principle differences underlying several variations of the task. Five variants of the task were used. An unconstrained reaching, two constrained at the focal level and two …

AdultMaleSupport Vector MachineNeural NetworksComputer sciencePosturelcsh:MedicineElectromyographyKinematicsMotor ActivityDIAGNOSISCLASSIFICATIONTask (project management)03 medical and health sciences0302 clinical medicineDiscriminative modelmedicineHumanslcsh:ScienceMuscle SkeletalBiology030304 developmental biologyComputational NeuroscienceMotor Systems0303 health sciencesCOORDINATIONMultidisciplinaryMOVEMENTSmedicine.diagnostic_testbusiness.industryElectromyographylcsh:RUnivariateMotor controlPattern recognitionBiomechanical PhenomenaSupport vector machineKernel methodEQUILIBRIUMPATTERNSARM[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]lcsh:QArtificial intelligencebusiness030217 neurology & neurosurgeryResearch ArticleNeurosciencePloS one
researchProduct

Computer assisted evaluation of retinal vessels tortuosity in Fabry disease.

2012

. Purpose:  Fabry Disease (FD) is a rare X-linked metabolic disorder characterized by diffuse deposition of sphingolipids in many tissues. Retinal vessel tortuosity is a common ocular manifestation in FD and may represent a useful marker for the disease. Unfortunately its clinical evaluation is poorly reproducibile and alternative means of evaluation may be of interest. We tested a new semi-automatic software measuring retinal vessel tortuosity from eye fundus digital images in a group of FD patients. Methods:  Observational case-control study evaluating four mathematical parameters describing tortuosity (relative length, sum of angle metric [SOAM], product of angle distance [PAD], triangul…

AdultMaleSystemic diseasePathologymedicine.medical_specialtyAdolescentFundus (eye)TortuosityConjunctival Diseaseschemistry.chemical_compoundYoung AdultDisease severityRetinal DiseasesOphthalmologyImage Processing Computer-AssistedPhotographyMedicineHumansDiagnosis Computer-AssistedAgedbusiness.industryMetabolic disorderRetinal VesselsRetinalGeneral MedicineMiddle Agedmedicine.diseaseFabry diseaseOphthalmologychemistryCase-Control StudiesFabry DiseaseFemalebusinessClinical evaluationConjunctivaActa ophthalmologica
researchProduct

The planimetric Grothoff's criteria by cardiac magnetic resonance can improve the specificity of left ventricular non-compaction diagnosis in thalass…

2020

We differentiated the left ventricle non-compaction (LVNC) from hypertrabeculated myocardium due to a negative remodeling in thalassemia intermedia (TI) patients applying linear and planimetric criteria and comparing the cardiovascular magnetic resonance (CMR) findings. CMR images were analyzed in 181 TI patients enrolled in the Myocardial Iron Overload in Thalassemia Network and 27 patients with proved LVNC diagnosis. The CMR diagnostic criteria applied in TI patients were: a modified linear CMR Petersen’s criterion based on a more restrictive ratio of diastolic NC/C > 2.5 at segmental level and the combination of planimetric Grothoff’s criteria (percentage of trabeculated LV myocardial…

AdultMaleThalassemia intermedia · Magnetic resonance imaging · Isolated non-compaction of the ventricular myocardium · ventricular remodelingmedicine.medical_specialtyDatabases FactualThalassemiaIronDiastoleMagnetic Resonance Imaging CineVentricular Function LeftDiagnosis DifferentialYoung AdultPredictive Value of TestsInternal medicinemedicineHumansRadiology Nuclear Medicine and imagingVentricular remodelingCardiac imagingObserver VariationIsolated Noncompaction of the Ventricular Myocardiummedicine.diagnostic_testVentricular Remodelingbusiness.industryMyocardiumbeta-ThalassemiaReproducibility of ResultsMagnetic resonance imagingMiddle Agedmedicine.diseaseFibrosismedicine.anatomical_structureVentricleCase-Control StudiesCardiologyFemaleThalassemia intermediaCardiology and Cardiovascular MedicinebusinessCardiac magnetic resonanceCardiomyopathiesBiomarkers
researchProduct

Thanatophoric dysplasia in monozygotic twins discordant for cloverleaf skull: Prenatal diagnosis, clinical and pathological findings

1992

We present male monozygotic twins with thanatophoric dysplasia (TD) type I concordant for long bone abnormalities and discordant for cloverleaf skull. The twins were the product of the second pregnancy of unrelated parents, with advanced paternal age. Prenatal diagnosis and postmortem examination showed severe rhizomelic shortness of limbs, bowing of the long bones with "telephone-receiver" femora in both twins, and cloverleaf skull and hydrocephalus in one of them. It is now accepted that most of cases of TD, such as in the present report, represent an autosomal dominant mutation with a high new mutations rate.

AdultMaleThanatophoric DysplasiaThanatophoric dysplasiaLong bonePrenatal diagnosisUltrasonography PrenatalPregnancyDiseases in TwinsmedicineHumansFemurPathologicalGenetics (clinical)Pregnancybusiness.industrySkullCloverleaf skullTwins MonozygoticAnatomymedicine.diseaseHydrocephalusmedicine.anatomical_structureDysplasiaFemalebusinessHydrocephalusAmerican Journal of Medical Genetics
researchProduct

HIV rapid test in a community setting as a strategy to improve access to HIV testing: data from a multicentre experience in Italy

2019

4,000 new HIV diagnoses and approximately 800 AIDS cases are still reported annually in Italy. Improving public awareness and bringing out HIV-undiagnosed individuals are keystones to progress towards the control of the HIV epidemic. For this purpose, the Open HIV TEST project was organized and delivered by the Italian NGO Anlaids, together with local infectious diseases specialists, in order to provide free access to HIV testing outside the healthcare setting. Between October 2017 and February 2019 six Open HIV TEST initiatives were delivered in six Italian cities (3 northern cities, 1 central and 2 southern cities). In all, 581 people were tested: the overall prevalence of HIV test reacti…

AdultMaleTime FactorsAdolescenthealth promotion HIV infection prevention intervention HIV rapid test.AIDS SerodiagnosisHIV InfectionsMiddle AgedSettore MED/42 - Igiene Generale E ApplicataHealth Services AccessibilityYoung AdultItalyPrevalenceHumansFemaleCommunity Health ServicesRetrospective Studies
researchProduct

A retrospective study of the prevalence and characteristics of dens invaginatus in a sample of the Turkish population.

2012

Objective: The purpose of this study was to assess the prevalence of dens invaginatus and to classify the types of dens invaginatus in a sample of the Turkish population.. Study Design: A retrospective study was performed using periapical and panoramic radiographs of 5355 patients who presented to the Department of Oral Diagnosis and Radiology at the Ondokuz Mayıs University Dentistry Faculty between January 2009 and December 2010. Maxillary and mandibular anterior teeth were evaluated for the presence and characteristics of dens invaginatus. Statistical evaluation of the presence of dens invaginatus related to gender was performed by the Pearson chi-squared test. Results: Dens invaginatus …

AdultMaleTurkish populationAdolescentTurkeyvirusesTurkishLarge populationDentistryOdontologíadigestive systemcomplex mixturesDens invaginatusYoung Adultfluids and secretionsmedicinePrevalenceHumansDens invaginatusOral Diagnosisdens in denteGeneral DentistryAnterior teethAgedRetrospective StudiesPeriodontitisOral Medicine and Pathologybusiness.industryRetrospective cohort studydental anomalyMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saluddigestive system diseasesPeriapical lesionDens in DenteOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASSurgeryFemaleResearch-ArticlebusinessMedicina oral, patologia oral y cirugia bucal
researchProduct

Methodological Aspects of the Application of the Naka-Rushton Equation to Clinical Electroretinogram

1993

The nonlinear relation between stimulus intensity and response amplitude of the electroretinogram (ERG) scotopic b wave can be described by a curve based on the Naka-Rushton (NR) equation. Up to now, the NR equation has been used to assess the features of the normal and pathological ERG, but the best approach for a correct evaluation of the parameters is still debatable. The parameters are thought to be related to the different conditions of retinal activities. The method is well known in experimental laboratories but is quite unusual at the clinical level. In the present paper the derivative analysis of the NR function is proposed as an easier approach to understand the variations of the N…

AdultMaleX ChromosomeAdolescentLightElectrodiagnosisGenetic LinkageVisual AcuityDark AdaptationCataractRetinaCellular and Molecular NeuroscienceExperimental LaboratoriesOpticsRetinal DiseasesElectroretinographymedicineHumansResponse AmplitudeApplied mathematicsScotopic visionChildAgedMathematicsmedicine.diagnostic_testbusiness.industryDerivative analysisGeneral MedicineMiddle AgedSensory SystemsOphthalmologyFemalebusinessRetinitis PigmentosaElectroretinographyOphthalmic Research
researchProduct

Production of Anti-Endomysial Antibodies in Cultured Duodenal Mucosa: Usefulness in Coeliac Disease Diagnosis

2002

Although anti-endomysial antibodies (EmA) have been found in the supernatants of cultured intestinal mucosa from patients with coeliac disease (CD), in no study has the clinical reliability of this new diagnostic tool been investigated. Our aims were to evaluate the clinical usefulness of the in vitro production of EmA in CD diagnosis in consecutive patients with suspected CD, and to evaluate the reliability of the in vitro challenge in CD patients on a gluten-free diet (GFD).For the former aim, consecutive patients who were due to undergo intestinal biopsy for suspected diagnosis of CD were enrolled: according to the final diagnosis, these patients were divided into two groups: Group 1 com…

AdultMaleanti-endomysial antibodiemedicine.medical_specialtySettore MED/09 - Medicina InternaAdolescentDuodenumIn Vitro TechniquesSensitivity and SpecificityGastroenterologyGliadinCoeliac diseaseIntestinal mucosaImmunopathologyInternal medicineSuspected diagnosisHumansMedicineChildCells CulturedAgedbiologybusiness.industryGastroenterologyInfantReproducibility of ResultsMiddle Agedcultured duodenal mucosa: coeliac disease diagnosismedicine.diseaseAntibodies Anti-IdiotypicCeliac Diseasemedicine.anatomical_structureGastric MucosaChild PreschoolAntibody FormationDuodenumbiology.proteinDuodenal mucosaFemaleHistopathologyAntibodycoeliac disease diagnosis [anti-endomysial antibodies; cultured duodenal mucosa]businessScandinavian Journal of Gastroenterology
researchProduct

Hamartoma of the urinary bladder: case report and review of the literature.

1999

Bladder hamartoma is a rare benign entity with only eight cases reported in the literature thus far, and whose general imaging features have not, to our knowledge, been previously discussed. The purpose of this report is to review the literature and to discuss the imaging findings in one case of bladder hamartoma where US features were those of an inhomogeneous solid mass with an unechogenic center, which was in accordance with the CT findings of a soft tissue mass with central inhomogeneous enhancement due to central necrosis.

AdultMalecongenital hereditary and neonatal diseases and abnormalitiesPathologymedicine.medical_specialtyHamartomaUrinary BladderCentral necrosisCystectomyDiagnosis DifferentialMedicineSoft tissue massHamartomaHumansRadiology Nuclear Medicine and imagingCt findingsNeuroradiologyUltrasonographyUrinary bladdermedicine.diagnostic_testbusiness.industryUrinary Bladder DiseasesSolid massInterventional radiologyGeneral Medicinemedicine.diseasemedicine.anatomical_structureRadiologybusinessTomography X-Ray ComputedEuropean radiology
researchProduct