Search results for "diagnostic techniques"

showing 10 items of 122 documents

Comparison of loop-mediated isothermal amplification (LAMP) and PCR for the diagnosis of infection with Trypanosoma brucei ssp. in equids in The Gamb…

2020

Introduction:\ud Infection of equids with Trypanosoma brucei (T. brucei) ssp. is of socioeconomic importance across sub-Saharan Africa as the disease often progresses to cause fatal meningoencephalitis. Loop-mediated isothermal amplification (LAMP) has been developed as a cost-effective molecular diagnostic test and is potentially applicable for use in field-based laboratories.\ud \ud Part I:\ud Threshold levels for T. brucei ssp. detection by LAMP were determined using whole equine blood specimens spiked with known concentrations of parasites. Results were compared to OIE antemortem gold standard of T. brucei-PCR (TBR-PCR).\ud \ud Results I:\ud Threshold for detection of T. brucei ssp. on …

Male0301 basic medicineVeterinary medicinePhysiologySurfactantsArtificial Gene Amplification and ExtensionPolymerase Chain Reactionlaw.inventionMedical Conditions0302 clinical medicinelawZoonosesMedicine and Health SciencesProspective StudiesDNA extractionMaterialsPolymerase chain reactionWhole bloodProtozoansMultidisciplinaryQREukaryotaMeningoencephalitisBody FluidsBloodInfectious DiseasesMolecular Diagnostic TechniquesPhysical SciencesMedicineFemaleGambiaAnatomyNucleic Acid Amplification TechniquesResearch ArticleTrypanosomaScienceTrypanosoma brucei bruceiMaterials ScienceDetergents030231 tropical medicineLoop-mediated isothermal amplificationContext (language use)BiologyTrypanosoma bruceiSensitivity and Specificity03 medical and health sciencesExtraction techniquesTrypanosomiasisTrypanosoma BruceiParasitic DiseasesmedicineAnimalsHorsesMolecular Biology TechniquesMolecular BiologyProtozoan InfectionsOrganismsBiology and Life SciencesGold standard (test)DNA Protozoanmedicine.diseasebiology.organism_classificationDNA extractionParasitic ProtozoansResearch and analysis methodsCross-Sectional StudiesTrypanosomiasis African030104 developmental biologyHorse DiseasesTrypanosoma Brucei GambiensePLOS ONE
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Comparison of body mass index (BMI) with the CUN-BAE body adiposity estimator in the prediction of hypertension and type 2 diabetes

2016

BACKGROUND: Obesity is a world-wide epidemic whose prevalence is underestimated by BMI measurements, but CUN-BAE (Clínica Universidad de Navarra - Body Adiposity Estimator) estimates the percentage of body fat (BF) while incorporating information on sex and age, thus giving a better match. Our aim is to compare the BMI and CUN-BAE in determining the population attributable fraction (AFp) for obesity as a cause of chronic diseases. METHODS: We calculated the Pearson correlation coefficient between BMI and CUN-BAE, the Kappa index and the internal validity of the BMI. The risks of arterial hypertension (AHT) and diabetes mellitus (DM) and the AFp for obesity were assessed using both the BMI a…

Male:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Anthropometry [Medical Subject Headings]:Health Care::Environment and Public Health::Public Health::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cross-Sectional Studies [Medical Subject Headings]ObesidadType 2 diabetesÍndice de masa corporalCUN-BAEBody Mass Index:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Diabetes mellitus0302 clinical medicineMedicine030212 general & internal medicineBody mass indexAdiposity:Persons::Persons::Age Groups::Adult::Aged [Medical Subject Headings]education.field_of_studyDiabetisAnthropometryDiabetes:Diseases::Pathological Conditions Signs and Symptoms::Signs and Symptoms::Body Weight::Overweight::Obesity [Medical Subject Headings]Middle Aged:Anatomy::Tissues::Connective Tissue::Adipose Tissue [Medical Subject Headings]CausalityAdipose TissueBody fatHypertensionObesitatFemaleHipertensióResearch ArticleAdultmedicine.medical_specialty:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Anthropometry::Body Weights and Measures::Body Mass Index [Medical Subject Headings]Population:Check Tags::Male [Medical Subject Headings]030209 endocrinology & metabolismBody adiposity index:Health Care::Environment and Public Health::Public Health::Epidemiologic Factors::Causality [Medical Subject Headings]03 medical and health sciences:Diseases::Cardiovascular Diseases::Vascular Diseases::Hypertension [Medical Subject Headings]Population attributable fractionClassification of obesityInternal medicineHipertensiónHumansObesityeducation:Persons::Persons::Age Groups::Adult [Medical Subject Headings]Aged:Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Composition::Body Fat Distribution::Adiposity [Medical Subject Headings]Body volume indexbusiness.industryPublic Health Environmental and Occupational Health:Diseases::Endocrine System Diseases::Diabetes Mellitus::Diabetes Mellitus Type 2 [Medical Subject Headings]:Persons::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings]medicine.diseaseObesityCross-Sectional StudiesEndocrinologyDiabetes Mellitus Type 2:Check Tags::Female [Medical Subject Headings]Attributable riskbusinessBody mass indexDemographyAntropometria
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Management and prognosis of pancreatic cancer over a 30-year period.

2009

BACKGROUND: The aim of this study was to report on changes in the diagnostic assessment, patterns of care and survival over time for pancreatic cancers. METHODS: A total of 2986 cases of pancreatic cancer from the Digestive Cancer Registry of Burgundy (France) over a 30-year period (1976–2005) were considered. Non-conditional logistic regressions were carried out to identify the factors associated with resection for cure and with the use of chemotherapy. A multivariate relative survival analysis was carried out. RESULTS: Diagnostic procedures have changed. Ultrasonography and computed tomography progressively have become the major diagnostic procedures. There was a slight improvement in sta…

MaleCancer Researchmedicine.medical_specialtyMultivariate analysisPancreatic diseasemedicine.medical_treatmentpancreatic cancerGastroenterologysurvivalstage at diagnosisInternal medicinePancreatic cancerClinical StudiesmedicineHumanscancer registryStage (cooking)Diagnostic Techniques and ProceduresAgedNeoplasm StagingAged 80 and overChemotherapyRelative survivalbusiness.industryCancerMiddle Agedmedicine.diseasePrognosisSurgeryCancer registryPancreatic NeoplasmsLogistic ModelsOncologyMultivariate AnalysisFemalebusinessmanagementBritish journal of cancer
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Clinicopathological profile of gastrointestinal tuberculosis: a multinational ID-IRI study

2020

Data are relatively scarce on gastro-intestinal tuberculosis (GITB). Most studies are old and from single centers, or did not include immunosuppressed patients. Thus, we aimed to determine the clinical, radiological, and laboratory profiles of GITB. We included adults with proven GITB treated between 2000 and 2018. Patients were enrolled from 21 referral centers in 8 countries (Belgium, Egypt, France, Italy, Kazakhstan, Saudi Arabia, UK, and Turkey). One hundred four patients were included. Terminal ileum (n = 46, 44.2%), small intestines except terminal ileum (n = 36, 34.6%), colon (n = 29, 27.8%), stomach (n = 6, 5.7%), and perianal (one patient) were the sites of GITB. One-third of all p…

MaleCirrhosismedicine.medical_treatmentretrospective studylaparoscopyColonoscopymultimodal imagingComorbidityGastroenterologyprotionamide0302 clinical medicineLaparotomyAscitesamikacinMedicinebedaquilinePathologie maladies infectieusesintestine biopsyadultsteroidclinical trialGeneral MedicinerifabutinMicrobiologie et protistologie [entomologiephytoparasitolog.]priority journaldiabetes mellitushistopathologybiological productMicrobiology (medical)Microbiologie et protistologie [parasitologie hum. et anim.]medicine.medical_specialtyTuberculosis030106 microbiologymalignant neoplasmArticle03 medical and health scienceslaparotomyHuman immunodeficiency virus infectionmolecular diagnosisHumansTuberculosisGastro-intestinalhumanRetrospective Studiescolondisease predispositionmicrobiologyTuberculosis; Immune-suppression; Gastro-intestinal; Endoscopy;anusmedicine.diseasemajor clinical studymulticenter studyaminosalicylic acidcyclophosphamide0301 basic medicineBiopsyAntitubercular Agentsethambutolrifampicinterminal ileumcolonoscopyofloxacin030212 general & internal medicineLaparoscopyazathioprinemedicine.diagnostic_testIncidence (epidemiology)gastrointestinal tuberculosisDisease Managementchronic kidney failurecycloserineInfectious DiseasesfemaleTreatment OutcomeMolecular Diagnostic Techniquesdiagnostic testDisease Susceptibilitymedicine.symptommoxifloxacinSymptom AssessmentImmune-suppressionstomachisoniazidpyrazinamidestreptomycinliver cirrhosispatient referrallinezolidInternal medicineBiopsybusiness.industryEndoscopyMycobacterium tuberculosishuman tissueclinical featureTreatmentTuberculosis Gastrointestinaltuberculostatic agentbusinessMicrobiologie et protistologie [bacteriol.virolog.mycolog.]
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Polymorphisms in endothelin system genes, arsenic levels and obesity risk.

2015

Background/objectivesObesity has been linked to morbidity and mortality through increased risk for many chronic diseases. Endothelin (EDN) system has been related to endothelial function but it can be involved in lipid metabolism regulation: Receptor type A (EDNRA) activates lipolysis in adipocytes, the two endothelin receptors mediate arsenic-stimulated adipocyte dysfunction, and endothelin system can regulate adiposity by modulating adiponectin activity in different situations and, therefore, influence obesity development. The aim of the present study was to analyze if single nucleotide polymorphisms (SNPs) in the EDN system could be associated with human obesity.Subjects/methodsWe analyz…

MaleEspañaObesidad:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Body Constitution::Body Weights and Measures::Body Fat Distribution::Adiposity [Medical Subject Headings]Endothelins:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]:Chemicals and Drugs::Biological Factors::Intercellular Signaling Peptides and Proteins::Endothelins [Medical Subject Headings]Polymorphism (computer science)Risk Factors:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Body Constitution::Body Weights and Measures::Body Size::Body Weight::Overweight::Obesity [Medical Subject Headings]:Chemicals and Drugs::Inorganic Chemicals::Elements::Arsenic [Medical Subject Headings]:Geographicals::Geographic Locations::Europe::Spain [Medical Subject Headings]education.field_of_studyMultidisciplinary:Diseases::Pathological Conditions Signs and Symptoms::Pathologic Processes::Disease Attributes::Chronic Disease [Medical Subject Headings]Genètica humanaEndothelinsQRMiddle AgedPrognosisReceptor Endothelin APolimorfismo de nucleótido único:Anatomy::Cells::Connective Tissue Cells::Adipocytes [Medical Subject Headings]ObesitatMedicineFemaleTomografía computarizada por rayos X:Phenomena and Processes::Genetic Phenomena::Genotype [Medical Subject Headings]Endothelin receptor:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Image Interpretation Computer-Assisted::Tomography X-Ray Computed [Medical Subject Headings]Research Articlemedicine.hormonemedicine.medical_specialtyGenotype:Phenomena and Processes::Mathematical Concepts::Probability::Risk [Medical Subject Headings]SciencePopulationSingle-nucleotide polymorphism:Phenomena and Processes::Metabolic Phenomena::Metabolism::Lipid Metabolism::Lipolysis [Medical Subject Headings]BiologyPolymorphism Single NucleotideArsenicReceptores de endotelinasInternal medicineAdipocitos:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Membrane Proteins::Receptors Cell Surface::Receptors Peptide::Receptors Endothelin [Medical Subject Headings]medicineHumansGenetic Predisposition to DiseaseObesityeducation:Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism Genetic::Polymorphism Single Nucleotide [Medical Subject Headings]AdiponectinHaplotypeEnfermedad crónicamedicine.diseaseObesityEndocrinologyHaplotypesSpain:Chemicals and Drugs::Biological Factors::Intercellular Signaling Peptides and Proteins::Adipokines::Adiponectin [Medical Subject Headings]GenotipoFollow-Up StudiesArsénicoPLoS ONE
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The Evonik-Mainz-Eye-Care-Study (EMECS): Design and Execution of the Screening Investigation

2014

Purpose To determine if screening for major ophthalmological diseases is feasible within the frame of routine occupational medicine examinations in a large working population. Methods 13037 employees of Evonik Industries aged 40 to 65 years were invited to be screened for major ophthalmological diseases (glaucoma, age related macular degeneration and diabetic retinopathy between June 2007 and March 2008 within an extended setting of occupational medicine. Ophthalmological examinations consisted of visual acuity, objective refraction, pachymetry, tonometry, perimetry (frequency doubling technology), confocal scanning laser ophthalmoscopy and digital fundus photography. Participants responded…

MaleHealth ScreeningVisual acuityEye DiseasesCross-sectional studyOccupational Health Serviceslcsh:MedicineGlaucomaDiagnostic Techniques OphthalmologicalGermanyMedicine and Health SciencesMass ScreeningPublic and Occupational HealthPublic Health Surveillancelcsh:ScienceMultidisciplinarymedicine.diagnostic_testDiabetic retinopathyMiddle AgedSocioeconomic Aspects of HealthRetinal DisordersFemalemedicine.symptomResearch ArticleAdultmedicine.medical_specialtyOccupational medicineAge DistributionSex FactorsmedicineHumansMass screeningAgedHealth Care Policybusiness.industrylcsh:RFundus photographyGlaucomaOccupational and Industrial Medicinemedicine.diseaseHealth CareOphthalmologyCross-Sectional StudiesSocial history (medicine)Macular DisordersOptometrylcsh:QPreventive MedicinebusinessScreening GuidelinesPLoS ONE
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Adherence to the Mediterranean Lifestyle and Desired Body Weight Loss in a Mediterranean Adult Population with Overweight: A PREDIMED-Plus Study

2020

Background. Body weight dissatisfaction is a hindrance to following a healthy lifestyle and it has been associated with weight concerns. Objectives. The aim of this study was to assess the association between the adherence to the Mediterranean lifestyle (diet and exercise) and the desired body weight loss in an adult Mediterranean population with overweight. Methods. Cross-sectional analysis in 6355 participants (3268 men; 3087 women) with metabolic syndrome and BMI (Body mass index) between 27.0 and 40.0 kg/m2 (55–75 years old) from the PREDIMED-Plus trial. Desired weight loss was the percentage of weight that participants wished to lose. It was categorized into four cut-offs of this perce…

MaleMediterranean dietObesidadejercicio físicoBody Mass Index:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]0302 clinical medicineSurveys and QuestionnairesAntineoplastic Combined Chemotherapy ProtocolsMedicinemediana edadeducation.field_of_studyanciano:Health Care::Health Care Quality Access and Evaluation::Quality of Health Care::Epidemiologic Factors::Age Factors [Medical Subject Headings]dietaprotocolos de quimioterapia antineoplásica combinada3. Good healthOlder adultsmetotrexatoprogramas de reducción de pesoObesitatlcsh:Nutrition. Foods and food supplyPersonas mayores frágilesIdeal weightLifestyles:Check Tags::Male [Medical Subject Headings]lcsh:TX341-641ArticleEstilo de vida03 medical and health sciences:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Body Constitution::Body Weights and Measures::Body Size::Body Weight::Overweight [Medical Subject Headings]:Anthropology Education Sociology and Social Phenomena::Human Activities::Exercise [Medical Subject Headings]ifosfamidaHumanscisplatinoIfosfamideeducationExerciseAgedconducta alimentaria:Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Metabolic Syndrome X [Medical Subject Headings]:Persons::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings]:Psychiatry and Psychology::Behavior and Behavior Mechanisms::Psychology Social::Life Style [Medical Subject Headings]PREDIMED-Plusmedicine.diseaseObesityMethotrexate:Check Tags::Female [Medical Subject Headings]Desired weight lossMetabolic syndromeCisplatinBody mass indexDemographyobesitycumplimiento del pacientehumanos:Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Mass Index [Medical Subject Headings]Ideal Body Weightdesired weight loss:Health Care::Health Care Facilities Manpower and Services::Health Promotion::Weight Reduction Programs [Medical Subject Headings]OverweightDiet MediterraneanMediterranean lifestyle:Health Care::Health Care Facilities Manpower and Services::Health Services::Preventive Health Services::Health Promotion::Healthy People Programs [Medical Subject Headings]Weight loss030212 general & internal medicine:Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Health Behavior::Patient Compliance [Medical Subject Headings]Abdominal obesityolder adults:Persons::Persons::Age Groups::Adult::Aged [Medical Subject Headings]2. Zero hungerNutrition and Dieteticsmediterranean lifestylesobrepeso:Analytical Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Nutrition Therapy::Diet Therapy::Diet Mediterranean [Medical Subject Headings]Age Factorsideal weightMiddle AgedPeso corporal ideal:Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Body Weight::Ideal Body Weight [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cross-Sectional Studies [Medical Subject Headings]Weight Reduction ProgramsBody imageFemalemedicine.symptompeso corporal idealEstils de vidadoxorrubicinabody imagePopulationImagen corporal030209 endocrinology & metabolism:Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Feeding Behavior [Medical Subject Headings]overweightHealthy LifestyleObesity:Geographical Locations::Geographic Locations::Europe::Spain [Medical Subject Headings]business.industryíndice de masa corporalFeeding BehaviorOverweightDieta mediterráneaDietDoxorubicinSobrepesoPatient Compliance:Psychiatry and Psychology::Psychological Phenomena and Processes::Mental Processes::Perception::Body Image [Medical Subject Headings]businessFood Science
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Response to letter by Werner et al.

2012

MalePain Thresholdbusiness.industrySensationDiagnostic Techniques NeurologicalAnesthesiology and Pain MedicineNeurologyResearch DesignSensation DisordersHumansNeuralgiaMedicineFemaleNeurology (clinical)businessPain
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Amyloidosis and Ocular Involvement: an Overview.

2019

Purpose: To describe the ophthalmic manifestations of amyloidosis and the corresponding therapeutic measures.Methods: The 178 patients included in the study had different types of amyloidosis, diagnosed at a single internal medicine institution (Bari, Italy). To provide a comprehensive review of the types of amyloidosis that can be associated with ocular involvement, the images and clinical descriptions of patients with amyloidosis structurally related to gelsolin, keratoepithelin and lactoferrin were obtained in collaborations with the ophthalmology departments of hospitals in Mainz (Germany) and Helsinki (Finland).Results: Overall, ocular morbidity was detected in 41 of the 178 patients w…

MalePathologymedicine.medical_specialtygenetic structuresEye Diseasesmedicine.medical_treatmentCorneal dystrophyDiagnostic Techniques OphthalmologicalEye03 medical and health sciences0302 clinical medicineAA amyloidosismedicineAL amyloidosisHumansCorneal transplantationCorneal epitheliumRetrospective Studiesbiologybusiness.industryAmyloidosisGeneral MedicineAmyloidosisMiddle Agedmedicine.diseaseeye diseases3. Good healthOphthalmologyTransthyretinmedicine.anatomical_structure030221 ophthalmology & optometrybiology.proteinLattice corneal dystrophyFemalesense organsbusiness030217 neurology & neurosurgeryFollow-Up StudiesSeminars in ophthalmology
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EAU Guidelines on Vesicoureteral Reflux in Children

2012

Context: Primary vesicoureteral reflux (VUR) is a common congenital urinary tract abnormality in children. There is considerable controversy regarding its management. Preservation of kidney function is the main goal of treatment, which necessitates identification of patients requiring early intervention.Objective: To present a management approach for VUR based on early risk assessment.Evidence acquisition: A literature search was performed and the data reviewed. From selected papers, data were extracted and analyzed with a focus on risk stratification. The authors recognize that there are limited high-level data on which to base unequivocal recommendations, necessitating a revisiting of thi…

MalePediatricsACID SCINTIGRAPHYmedicine.medical_treatmentKidneyurologic and male genital diseasesPediatricsVOIDING CYSTOURETHROGRAPHYURETERAL REIMPLANTATIONMedicineAntibiotic prophylaxisFamily historyChildChildrenNEONATAL HYDRONEPHROSISReimplantationUrinary tract infectionVesicoureteral refluxDiagnostic Techniques Urologicalfemale genital diseases and pregnancy complicationsAnti-Bacterial AgentsTreatment OutcomeRenal scarringBulking agentsEAUPREDICTIVE FACTORSChild PreschoolPredictive value of testsUrologic Surgical ProceduresFemaleRisk assessmentmedicine.medical_specialtyUrologyUrinary systemContext (language use)GuidelinesVesicoureteral refluxURINARY-TRACT-INFECTIONANTIBIOTIC-PROPHYLAXISPredictive Value of TestsHumansWatchful WaitingVesico-Ureteral RefluxProphylaxisbusiness.industryInfantEndoscopymedicine.diseaseVURSurgeryISOLATED ANTENATAL HYDRONEPHROSISEarly DiagnosisRENAL DAMAGESPONTANEOUS RESOLUTIONLaparoscopybusinessWatchful waitingEuropean Urology
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