Search results for "diaphragm"

showing 10 items of 96 documents

Evaluation of esophageal motility and reflux in children treated for congenital diaphragmatic hernia with the use of combined multichannel intralumin…

2011

Abstract Background Gastroesophageal reflux (GER) is frequently observed in children treated for congenital diaphragmatic hernia (CDH) at birth, as well as esophageal dysmotility, that has been hypothesized to be caused by innervatory anomalies. The aim of this study is to evaluate GER and dysmotility in young patients with CDH using pH-multichannel intraluminal impedance. Methods Thirty children (17 boys and 13 girls) who underwent repair for CDH between 2002 and 2007 with a median age of 5.2 years (range, 3-10 years) were included in the study. All patients were operated on with a subcostal laparotomy incision and had a left-sided diaphragmatic defect. The defect repair required an artifi…

Malemedicine.medical_specialtymedicine.medical_treatmentMonitoring AmbulatoryCongenital diaphragmatic herniaGastroenterologyPh monitoringPostoperative ComplicationsSwallowingInternal medicineLaparotomyElectric ImpedanceHumansMedicineEsophageal Motility DisordersChildHernia Diaphragmaticbusiness.industryIncidenceEsophageal motilitySettore MED/20 - Chirurgia Pediatrica E InfantileRefluxCongenital diaphragmatic herniaGastric Acidity DeterminationGeneral MedicineHydrogen-Ion Concentrationmedicine.diseaseDeglutitionSurgeryTreatment OutcomeEsophageal motility disorderGastroesophageal refluxIntraluminal multichannel impedanceChild PreschoolAtresiaPediatrics Perinatology and Child HealthFemaleSurgeryHernias Diaphragmatic CongenitalbusinessEsophageal motility
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Ultrasound imaging assessment of the diaphragm and abdominal muscles in people with a recent history of moderate Covid-19 infection and healthy parti…

2023

Coronavirus disease (Covid-19) is a highly infectious disease caused by the SARS-CoV-2 virus and is associated with a decrease of respiratory, physical, and psychological function, subsequently affecting quality of life. The aim of the present pilot study was to use ultrasound imaging (USI) to evaluate and compare the thickness of the diaphragm and abdominal muscles between individuals recently diagnosed with moderate Covid-19 infection and healthy individuals. Methods: A cross-sectional observational pilot study was performed. A total sample of 24 participants were recruited from a private medical center (Madrid, Spain): Covid-19 (n = 12) and healthy controls (n = 12). The external oblique…

MultidisciplinaryMedicina InvestigacióThoracic diaphragmAbdominalesInfecciones respiratoriasVirus testingRespiratory infectionsImagen por ultrasonidosVirusPilot studiesDiafragma torácicoContracción muscularMuscle contractionAbdominal musclesEstudios pilotoCovid-19Ultrasound imaging
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A maChine and deep Learning Approach to predict pulmoNary hyperteNsIon in newbornS with congenital diaphragmatic Hernia (CLANNISH): Protocol for a re…

2021

Introduction Outcome predictions of patients with congenital diaphragmatic hernia (CDH) still have some limitations in the prenatal estimate of postnatal pulmonary hypertension (PH). We propose applying Machine Learning (ML), and Deep Learning (DL) approaches to fetuses and newborns with CDH to develop forecasting models in prenatal epoch, based on the integrated analysis of clinical data, to provide neonatal PH as the first outcome and, possibly: favorable response to fetal endoscopic tracheal occlusion (FETO), need for Extracorporeal Membrane Oxygenation (ECMO), survival to ECMO, and death. Moreover, we plan to produce a (semi)automatic fetus lung segmentation system in Magnetic Resonanc…

Pediatricsmedicine.medical_treatmentretrospective studyDiagnostic RadiologyCohort StudiesStudy ProtocolMathematical and Statistical TechniquesPregnancyMedicine and Health SciencesLung volumesMultidisciplinarymedicine.diagnostic_testRadiology and ImagingStatisticsQRSoftware EngineeringMagnetic Resonance ImagingPulmonary Imagingmachine learningObstetric ProceduresPhysical SciencesEngineering and TechnologyMedicineFemaleCohort studyComputer and Information Sciencesmedicine.medical_specialtyImaging TechniquesHypertension PulmonaryScienceSurgical and Invasive Medical ProceduresResearch and Analysis MethodsPulmonary hypertensionComputer SoftwareDiagnostic MedicineArtificial IntelligenceCongenital Diaphragmatic Hernia Pulmonary Ipertension Deep Learning protocolmedicineExtracorporeal membrane oxygenationHumansHerniaStatistical MethodsRetrospective StudiesFetal surgerybusiness.industrydiaphragmatic herniasegmentationInfant NewbornBiology and Life SciencesNeonatesCongenital diaphragmatic herniadeep learningRetrospective cohort studyMagnetic resonance imagingmedicine.diseaseSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Hernias Diaphragmatic CongenitalbusinessMathematicsDevelopmental BiologyForecasting
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�ber die Wirkung des Salyrgan auf das isolierte Rattenzwerchfell

1953

Das Natriumsalz des 3-Oxymercuri-2-methoxy-propylamids des Salicylsaureglykolsaureathers = Salyrgan ruft in Konzentrationen 1:103 bis 1:2×103 am isolierten Rattenzwerchfell folgende Effekte hervor: 1. Fibrillationen, die mit Aktionspotentialen einhergehen, 2. eine Verzogerung der Erschlaffung einer elektrisch ausgelosten Kontraktion, 3. einen „ersten Tonusanstieg“, 4. Erloschen der elektrischen Erregbarkeit und 5. einen langsamen „zweiten Tonusanstieg“, der in eine Dauerverkurzung ubergeht.

PharmacologyChemistryPharmacology toxicologyRat DiaphragmGeneral MedicineMolecular biologyNaunyn-Schmiedebergs Archiv f�r Experimentelle Pathologie und Pharmakologie
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�ber die Wirkung hypotoner Salzl�sungen auf das Rattenzwerchfell

1954

Es wird die Wirkung hypotoner Salzlosungen auf das isolierte Rattenzwerchfell beschrieben. Auf 5/10–6/10 der Isotonie verdunnte Tyrodelosungen fuhren an Muskeln, die bereits langere Zeit im Versuch sind, zu einer dauernden Verstarkung der elektrisch ausgelosten Kontraktionen („hypotoner Effekt“). Mit Saccharose auf Warmbluterisotonie erganzte hypotone Salzlosungen zeigen diesen Effekt nicht. Vermehrung des Kaliums oder Calciums im Austausch gegen Natrium bei erhaltener Hypotonie hemmt den „hypotonen Effekt“, Senkung der Badetemperatur hebt ihn ebenfalls auf.

PharmacologyChemistryPharmacology toxicologyTonicityRat DiaphragmGeneral MedicineMolecular biologyNaunyn-Schmiedebergs Archiv f�r Experimentelle Pathologie und Pharmakologie
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�ber die Wirkung von Acetylcholin auf die mechanischen und elektrischen Eigenschaften des denervierten Rattenzwerchfells unter dem Einflu� verschiede…

1959

PharmacologyChemistryPharmacology toxicologymedicineRat DiaphragmGeneral MedicinePharmacologyAcetylcholinemedicine.drugNaunyn-Schmiedeberg's Archiv f�r Experimentelle Pathologie und Pharmakologie
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Die Wirkung von Acetylcholin, Dekamethonium und d-Tubocurarin am isolierten Rattenzwerchfell in Abh�ngigkeit von der Denervationsdauer

1955

An 41 isolierten Zwerchfellpraparaten der Ratte wurde zu verschiedenen Zeitpunkten nach Exharese des N. phrenicus die Wirkung von Acetylcholin (Ach), Decamethonium (C 10) und d-Tubocurarin (dTc) untersucht. Die Reaktionen des Muskels zeigten eine charakteristische Abhangigkeit von der Denervationsdauer. Ach verursachte eine Verminderung der Hubhohe elektrisch ausgeloster Einzelzuckungen, Kontraktur und Kontraktur-Ruckstand. Die Wirkung von C 10 ahnelte der von Ach weitgehend. Dagegen fuhrte Gabe von dTc zu einer Senkung der „Grundlinie“ und zur Verminderung der Hubhohe der Einzelzuckungen.

PharmacologyDenervationD-TubocurarineDecamethoniumChemistryPharmacology toxicologymedicineRat DiaphragmGeneral MedicinePharmacologyAcetylcholinemedicine.drugNaunyn-Schmiedebergs Archiv f�r Experimentelle Pathologie und Pharmakologie
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Über den Einfluss von Acetylcholin auf das Membranpotential denervierter Rattenzwerchfelle

1957

The membran potential of isolated rat-diaphragms has been measured by means of intracellular micro-electrodes, in order to study changes of the resting potential and of the depolarizing action of acetylcholine after section of the phrenic nerve. Within 80 days after denervation, the membrane potential was found to fall exponentially from 87 mV to 66 mV. The action of acetylcholine, on the other hand, was found to be independent of the duration of denervation: between the 4th and the 80th day of denervation: 10−5g/ml acetylcholine always caused the membrane potential to fall by an average of the 9 mV.

PharmacologyDenervationMembrane potentialmedicine.medical_specialtyChemistryDepolarizationCell BiologyResting potentialCellular and Molecular NeuroscienceEndocrinologyInternal medicinemedicineMolecular MedicineRat DiaphragmMolecular BiologyIntracellularAcetylcholinemedicine.drugPhrenic nerveExperientia
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Der Einflu� von Monojodessigs�ure auf das Aktionspotential des Rattenzwerchfells

1959

1. The action of iodoacetic acid (IA) was studied on the isolated rat diaphragm at 20–22° C. Membrane and action potentials were led off with intracellular microelectrodes. 2. IA causes a contracture which is complete in 4 hours. As long as t he contracture develops, the membrane potential remains constant. A contracture identical with that seen in a normal preparation can be produced by IA in the presence of isotonic K2SO4. 3. The amplitude of the action potential is only slightly reduced during the first two hours after addition of IA. The duration of the action potential is significantly increased. Finally, action potentials with a plateau are obtained which resemble those of normal vent…

PharmacologyMembrane potentialMembrane permeabilityIodoacetic acidSodiumPotassiumchemistry.chemical_elementGeneral MedicineDiaphragm (structural system)chemistry.chemical_compoundchemistryBiochemistryExtracellularBiophysicsmedicineContracturemedicine.symptomNaunyn-Schmiedebergs Archiv f�r Experimentelle Pathologie und Pharmakologie
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Die Wirkung thiolopriver Substanzen auf Membran-und Aktionspotential des Rattenzwerchfells

1958

Vor einiger Zei t wurde uber die Ver~nderungen des Membranpo ten t i a l s des i so l ier ten Ra t t enzwerchfe l l s du rch th io lopr ive Subs t anzen be r i ch t e t (MUSCKOLL 1956). Diese Versuche wurden einersei ts un te r nommen, u m eine e lekt rophys io logische Kl~Lrung der versch iedenen Ph£nomene herbeizufuhren , die a m isol ier ten Muskel oder auch in v ivo durch Quecks i lberd iure t ica au f t r e t en (siehe dazu KIYSCHI~SXY, M]mCXER, WESTERMA~N u. LULLMA~N). Andererse i t s schien es von In te resse fes tzuste l len, ob den K o n t r a k t u r e n , die durch d ie th io lopr iven Subs tanzen hervorgerufen wurden, auch zei t l ich koord in i e r t e Depo la r i sa t ionen de…

PharmacologyPhysicsStereochemistryPharmacology toxicologyRat DiaphragmGeneral MedicineNaunyn-Schmiedebergs Archiv f�r Experimentelle Pathologie und Pharmakologie
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