Search results for "dication"

showing 10 items of 733 documents

An aryl-fused redox-active tetrathiafulvalene with enhanced mixed-valence and radical-cation dimer stabilities.

2018

Molecular recognition of stable organic radicals is a relatively novel, but important structural binding motif in supramolecular chemistry. Here, we report on a redox-switchable veratrole-fused tetrathiafulvalene derivative VTTF which is ideally suited for this purpose and for the incorporation into stimuli-responsive systems. As revealed by electrochemistry, UV/Vis measurements, X-ray analysis, and electrocrystallisation, VTTF can be reversibly oxidised to the corresponding radical-cation or dication which shows optoelectronic and structural propterties similar to tetrathiafulvalene and tetrakis(methylthio)tetrathiafulvalene. However, theoretical calculations, variable temperature EPR, and…

010405 organic chemistryChemistryArylDimerRadicalOrganic ChemistrySupramolecular chemistry010402 general chemistry01 natural sciencesBiochemistrysupramolecular chemistry0104 chemical scienceslaw.inventionDicationchemistry.chemical_compoundCrystallographyRadical ionlawsupramolekulaarinen kemiaPhysical and Theoretical ChemistryElectron paramagnetic resonanceta116TetrathiafulvaleneOrganicbiomolecular chemistry
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Spiro-fused bis-hexa-peri-hexabenzocoronene.

2018

A spiro-fused hexa-peri-hexabenzocoronene dimer was synthesized, and its physicochemical properties were studied by UV-Vis absorption and emission spectroscopy as well as cyclic voltammetry. Chemical oxidation of SB-HBC afforded its radical cation and dication derivatives, which could be reversibly reduced to the neutral state.

010405 organic chemistryChemistryDimerMetals and AlloysHexa-peri-hexabenzocoroneneGeneral Chemistry010402 general chemistry01 natural sciencesCatalysis0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsDicationchemistry.chemical_compoundRadical ionPolymer chemistryMaterials ChemistryCeramics and CompositesEmission spectrumCyclic voltammetryAbsorption (chemistry)Neutral stateChemical communications (Cambridge, England)
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Self-assembly of the tetrachlorido(oxalato)rhenate( iv ) anion with protonated organic cations: X-ray structures and magnetic properties

2016

Two novel ReIV compounds of formulae [H2bpy][ReIVCl4(ox)] (1) and [H3biim]2[ReIVCl4(ox)] (2) [H2bpy2+ = 4,4′-bipyridinium dication, H3biim+ = 2,2′-biimidazolium monocation, and ox2− = oxalate dianion] have been synthesised and magneto-structurally characterised. 1 crystallises in the monoclinic system with space group C2/c, and 2 crystallises in the triclinic system with space group P[1 with combining macron]. The ReIV ion in 1 and 2 is six-coordinate, bonded to four chloride ions and two oxalate-oxygen atoms in a distorted octahedral geometry. Short intermolecular ReIV–Cl⋯Cl–ReIV contacts, Cl⋯π type interactions and hydrogen bonds are present in the crystal lattice of both compounds, gener…

010405 organic chemistryChemistryInorganic chemistrySupramolecular chemistryGeneral ChemistryCrystal structureTriclinic crystal system010402 general chemistryCondensed Matter Physics01 natural sciencesMagnetic susceptibilityOxalate0104 chemical sciencesDicationchemistry.chemical_compoundCrystallographyOctahedral molecular geometryGeneral Materials ScienceMonoclinic crystal system
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Radical cation and dication of a 4H-dithieno[2,3-b:3′,2′-e][1,4]-thiazine

2017

A p-tert-butylphenyl substituted 4H-dithieno[2,3-b:3′,2′-e][1,4]thiazine was synthesized by twofold Buchwald–Hartwig coupling. The electronic properties (UV/Vis, cyclic voltammetry and spectroelectrochemistry) and the DFT- and TD DFT-calculated electronic structure reveal that the parent system and the radical cation and dication oxidation products are highly polarizable π-systems with strong charge transfer contributions. The radical cation and the dication were prepared by oxidation with antimony(V) pentachloride, giving stable deeply colored salts. EPR spectroscopy of the radical cation furnishes hyperfine coupling constants with the nitrogen nucleus and the α-thienyl protons. The dicati…

010405 organic chemistryChemistryOrganic Chemistrychemistry.chemical_elementElectronic structureNuclear magnetic resonance spectroscopy010402 general chemistryPhotochemistry01 natural sciences0104 chemical scienceslaw.inventionDicationchemistry.chemical_compoundRadical ionAntimonyThiazinelawCyclic voltammetryElectron paramagnetic resonanceOrganic Chemistry Frontiers
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Mono‐ and Bis(imidazolidinium ethynyl) Cations and Reduction of the Latter To Give an Extended Bis‐1,4‐([3]Cumulene)‐ p ‐carboquinoid System

2018

An extended π-system containing two [3]cumulene fragments separated by a p-carboquinoid and stabilized by two capping N-heterocyclic carbenes (NHCs) has been prepared. Mono- and bis(imidazolidinium ethynyl) cations have also been synthesized from the reaction of an NHC with phenylethynyl bromide or 1,4-bis(bromoethynyl)benzene. Cyclic voltammetry coupled with synthetic and structural studies showed that the dication is readily reduced to a neutral, singlet bis-1,4-([3]cumulene)-p-carboquinoid as a result of the π-accepting properties of the capping NHCs.

010405 organic chemistryCumuleneGeneral Chemistry010402 general chemistryPhotochemistry01 natural sciencesMedicinal chemistryCatalysis0104 chemical sciences3. Good healthDicationchemistry.chemical_compoundchemistryBromideX-ray crystallographySinglet stateCyclic voltammetryBenzeneAngewandte Chemie International Edition
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Assessment of surface sediment dynamics and response of benthic macrofauna assemblages in Boughrara Lagoon (SW Mediterranean Sea)

2016

International audience; A study was conducted in the spring of 2009, the winters of 2010 and 2013, and in the summer of 2012 at 13 stations in Boughrara Lagoon, Tunisia (southern Mediterranean). The country’s largest lagoon, it is considered to be an anthropogenically stressed area, though a major tourist centre—Djerba Island—is located along its northern shores. The lagoon bottoms were studied via analyses of grain size, surface sediment composition, total organic matter (TOM) and through the trophic and functional organisation of benthic macrofauna. The results indicate that the bottoms are composed of fine, medium or coarse sands and that sediment distribution is controlled by water move…

0106 biological sciencesMediterranean climateGeneral Decision SciencesBenthic macrofauna010501 environmental sciences01 natural sciences[ SDE ] Environmental SciencesMediterranean seaEcosystem14. Life underwaterEcology Evolution Behavior and Systematics0105 earth and related environmental sciencesTrophic levelEcologyEcology010604 marine biology & hydrobiologyDetritivoreSedimentTotal organic matterParticle sizeSediment dynamicsTrophic structureBioindicationHabitat13. Climate actionBenthic zone[SDE]Environmental SciencesEnvironmental science
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Plant invasions on small Mediterranean islands. An overview

2016

Biological invasions have become one of the main drivers of habitat degradation and a leading cause of biodiversity loss in island ecosystems worldwide. The spread of invasive species poses a particular environmental threat on the islands of the Mediterranean Basin, which are hot spots of biodiversity and contain rare habitats and endemic species, especially on small islands, which are highly vulnerable to biodiversity loss. Following a recent survey, in this paper we aim to provide an overview of the present-day non-native vascular flora of small Mediterranean islands based on a sample of 37 islands located in the middle of the Mediterranean Sea, off the coast of Italy. By comparing the cu…

0106 biological sciencesMediterranean climatebiological invasionsBiodiversitynature conservationsucculencebiological invasionBiology010603 evolutionary biology01 natural sciencesMediterranean Basinecology evolution behavior and systematicsMediterranean seaeradicationEndemismEcology Evolution Behavior and SystematicsAcacia; biological invasions; cactaceae; Carpobrotus; eradication; established alien species; Italy; nature conservation; succulence; threats to global biodiversity; ecology evolution behavior and systematics; plant scienceEcologySettore BIO/02 - Botanica SistematicaAcaciaestablished alien speciesEcology Evolution Behavior and SystematicCarpobrotuestablished alien specieHabitat destructionplant scienceHabitatcactaceaeItalythreats to global biodiversitySettore BIO/03 - Botanica Ambientale E ApplicataCarpobrotusMediterranean Islands010606 plant biology & botany
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Can vegetation provide indications of ancient lake shorelines after more than one hundred years? A case study of Iskander-kul Lake, Tajikistan

2017

Abstract Bioindication is a common approach to assess and evaluate environmental changes over both short or long periods of time. Here we attempt to highlight that vegetation can provide indications of the palaeoshoreline of Lake Iskander-kul, even after at least 150 years. It is an example of a dammed lake that was created by a huge mass rockfall as a result of a strong earthquake during the late Pleistocene. Applying the two way indicator species analysis (TWINSPAN) we found that the shrubby vegetation is the particular one that can still effectively thrive along the palaeoshoreline despite the lake downlift. Using the phi coefficient as a fidelity measure for certain vegetation type, we …

0106 biological sciencesSteppeGeneral Decision Sciences010603 evolutionary biology01 natural sciencesVegetation typeScreeFestuca valesiacaEcology Evolution Behavior and Systematicspalaeoshorelinegeographygeography.geographical_feature_categoryEcologybiologyAncient lakeEcologyphytoindicationPlant communityenvironmental changeVegetationbiology.organism_classificationhydrological changesplant communitiesTwo-way indicator species analysis010606 plant biology & botanyEcological Indicators
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A 300 IR sublingual tablet is an effective, safe treatment for house dust mite-induced allergic rhinitis: An international, double-blind, placebo-con…

2021

Background: Allergic rhinitis induced by house dust mites (HDMs) is a highly prevalent but often underdiagnosed and undertreated/untreated chronic disease. It often has a negative impact on sleep, work, leisure activities, and health-related quality of life. Allergen immunotherapy is a proven, safe treatment for respiratory allergies. Objective: We sought to assess the efficacy and safety of a 300 index of reactivity (IR) sublingual tablet formulation of Dermatophagoides pteronyssinus:Dermatophagoides farinae 1:1 extract in adolescents (aged >_12) and adults with moderate to severe HDM-induced allergic rhinitis. Methods: In a phase III, international, double-blind, placebo controlled, rando…

0301 basic medicineAllergen immunotherapy; allergic rhinitis; allergy; house-dust mite; medication score; sublingual immunotherapy; symptom score; tablet; total combined scoreMaleAllergyInternational Cooperation*total combined scoreSeverity of Illness Indexlaw.invention0302 clinical medicineRandomized controlled triallaw*allergyClinical endpointImmunology and Allergy[SDV.IMM.ALL]Life Sciences [q-bio]/Immunology/Allergologyhouse dust miteAllergen immunotherapybiologyPyroglyphidae*tablet*allergic rhinitis*sublingual immunotherapy3. Good healthhouse-dust mitetotal combined score*Allergen immunotherapyFemale[SDV.IMM.IMM] Life Sciences [q-bio]/Immunology/Immunotherapy[SDV.IMM.ALL] Life Sciences [q-bio]/Immunology/Allergology*medication scoreAdultAllergen immunotherapymedicine.medical_specialtyAdolescentDrug-Related Side Effects and Adverse ReactionsImmunologyPlacebosublingual immunotherapymedication score03 medical and health sciencesYoung AdultDouble-Blind MethodInternal medicinemedicineAnimalsHumansAntigens DermatophagoidesAsthmaHouse dust mitetabletSublingual Immunotherapyallergic rhinitisbusiness.industry[SDV.IMM.IMM]Life Sciences [q-bio]/Immunology/Immunotherapymedicine.diseasebiology.organism_classificationallergyPlacebo EffectRhinitis Allergic*symptom scoresymptom scoreClinical trial030104 developmental biology030228 respiratory system*house-dust miteQuality of LifebusinessThe Journal of allergy and clinical immunology
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Peripheral artery disease, redox signaling, oxidative stress – Basic and clinical aspects

2017

Reactive oxygen and nitrogen species (ROS and RNS, e.g. H2O2, nitric oxide) confer redox regulation of essential cellular signaling pathways such as cell differentiation, proliferation, migration and apoptosis. At higher concentrations, ROS and RNS lead to oxidative stress and oxidative damage of biomolecules (e.g. via formation of peroxynitrite, fenton chemistry). Peripheral artery disease (PAD) is characterized by severe ischemic conditions in the periphery leading to intermittent claudication and critical limb ischemia (end stage). It is well known that redox biology and oxidative stress play an important role in this setting. We here discuss the major pathways of oxidative stress and re…

0301 basic medicineAntioxidantRedox signalingmedicine.medical_treatmentCellular differentiationClinical BiochemistryReview Article030204 cardiovascular system & hematologyPharmacologymedicine.disease_causeBiochemistrychemistry.chemical_compound0302 clinical medicineGene Regulatory Networks610 Medicine & healthlcsh:QH301-705.5chemistry.chemical_classificationlcsh:R5-920Anticholesteremic AgentsReactive Nitrogen Speciesmedicine.symptomlcsh:Medicine (General)Oxidation-ReductionPeroxynitriteSignal Transductionmedicine.medical_specialtyCell signalingAntioxidant therapy610 Medicine & healthNitric oxide03 medical and health sciencesPeripheral Arterial DiseasemedicineHumansExerciseReactive oxygen speciesbusiness.industryOrganic ChemistryClaudication and critical limb ischemiaWalking distanceIntermittent claudicationSurgeryOxidative Stress030104 developmental biologychemistrylcsh:Biology (General)Peripheral artery (occlusive) diseasebusinessReactive Oxygen SpeciesOxidative stressRedox Biology
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