Search results for "differentiation"

Differentiation in CLIL : methods and challenges

2014

CLIL (Content and Language Integrated Learning) -opetus eli vieraskielinen opetus tähtää sujuvaan kommunikaatioon ja monipuoliseen kielenkäyttöön ja tuo mukanaan uudenlaisia haasteita eriyttämisen saralle. CLIL on kohtalaisen uusi metodi Suomessa, eikä yksittäisiä opetuksen osa-alueita kuten eriyttämistä ole tutkittu sen osalta kovinkaan laajalti. Eriyttäminen antaa jokaisella oppilaalle mahdollisuuden kehittyä omalla lähikehityksen vyöhykkeellään ja siksi eriyttämistä on tärkeää tutkia myös vieraan kielen kannalta CLIL-opetuksessa. Tutkimuksen tavoitteena oli selvittää, minkälaisissa tilanteissa ja mitä keinoja käyttäen alakoulutason CLIL-opettajat eriyttävät omassa opetuksessaan ja mitkä …

Transfection of lipoma cells with papilloma bovine virus subgenomic fragment.

1991

Abstract Lipoma cells with consistent chromosomal aberration have been transfected with plasmids carrying papilloma bovine virus subgenomic fragment (PBV 69). The succesful transformation of the cells was ascerted on the changed growth pattern of the cells in liquid medium, colony formation in soft agar and modified cell appearrance in electron microscopy; transfection with PBV 69 has not been, however, sufficient to immortalize lipoma cells.

CVB3 VP1 interacts with MAT1 to inhibit cell proliferation by interfering with Cdk-activating kinase complex activity in CVB3-induced acute pancreati…

2021

Coxsackievirus B3 (CVB3) belongs to the genus Enterovirus of the family Picornaviridae and can cause acute acinar pancreatitis in adults. However, the molecular mechanisms of pathogenesis underlying CVB3-induced acute pancreatitis have remained unclear. In this study, we discovered that CVB3 capsid protein VP1 inhibited pancreatic cell proliferation and exerted strong cytopathic effects on HPAC cells. Through yeast two-hybrid, co-immunoprecipitation, and confocal microscopy, we show that Menage a trois 1 (MAT1), a subunit of the Cdk-Activating Kinase (CAK) complex involved in cell proliferation and transcription, is a novel interaction protein with CVB3 VP1. Moreover, CVB3 VP1 inhibited MAT…

Verkostot, paikallisuus ja eriarvoisuus

2012

Environmental Responsibility as a Factor in Gaining Competitive Advantage in the Aviation Industry

2015

In recent years there has been increasing interest in the environmental impacts of aviation, and some airlines have begun to address this issue more seriously. At the same time, competition in the aviation industry has become much tougher. This study focuses on the question of whether showing proactive environmental behavior could work as a differentiation strategy for airlines that are acting more responsibly, and thus help them to improve their competitiveness. This paper presents the results of a questionnaire conducted among 148 air travelers on their opinions and attitudes towards environmental aspects of flying, such as a modern and fuel-efficient fleet, direct flights, and carbon off…