Search results for "disability"

showing 10 items of 989 documents

Effects of immunomodulatory treatment with subcutaneous interferon beta-1a on cognitive decline in mildly disabled patients with relapsing-remitting …

2010

The objective of this study was to assess the effects of subcutaneous (sc) interferon beta-1a (IFNβ-1a) on cognition in mildly disabled patients with relapsing—remitting multiple sclerosis (RRMS). Patients aged 18—50 years with RRMS (McDonald criteria; Expanded Disability Status Scale score ≤4.0) were assigned IFNβ therapy at the physician’s discretion and underwent standardized magnetic resonance imaging, neurological examination and neuropsychological testing at the baseline and regular intervals for up to three years. This analysis included 459 patients who received sc IFNβ-1a (44 mcg: n = 236; 22 mcg: n = 223; three-year follow up was available for 318 patients). The hazard ratio for c…

Maleinterferon beta-1aKaplan-Meier EstimateRelapsing-RemittingNeuropsychological TestsCohort StudiesDisability EvaluationMedicineMale; Adolescent; Young Adult; Middle Aged; Kaplan-Meier Estimate; Cognition Disorders; Survival Analysis; Female; Disability Evaluation; Dose-Response Relationship Drug; Humans; Multiple Sclerosis Relapsing-Remitting; Prospective Studies; Cohort Studies; Disease Progression; Interferon-beta; Injections Subcutaneous; Neuropsychological Tests; Adult; Immunologic Factors; Endpoint DeterminationProspective StudiesProspective cohort studyinterferon beta multiple sclerosis cognitive impairmentSubcutaneousCognitive disorderHazard ratioMiddle AgedSettore MED/26 - NEUROLOGIANeurologyDisease ProgressionSettore MED/26 - NeurologiaFemaleDrugmedicine.drugAdultmedicine.medical_specialtyMultiple SclerosisAdolescentEndpoint DeterminationInjections SubcutaneousLower riskInjectionsDose-Response RelationshipYoung AdultMultiple Sclerosis Relapsing-RemittingInternal medicineHumansImmunologic Factorscognitive functioncognitive impairmentExpanded Disability Status ScaleDose-Response Relationship Drugbusiness.industryInterferon beta-1aMcDonald criteriaOdds ratioInterferon-betamedicine.diseaseSurvival AnalysisSurgerydisabilityNeurology (clinical)businessCognition Disorderscognitive function; cognitive impairment; disability; disease progression; interferon beta-1a; multiple sclerosis
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Authorship in Facilitated Communication: An Analysis of 11 Cases

2014

Abstract. We studied the authorship of messages produced through facilitated communication (FC) for all users of FC in two comprehensive schools in a small city in Finland. The participants were 11 children with intellectual disabilities, including autism, all having used FC from 1 to 3 years. The test conditions involved open and blind information-passing tasks in which the participants were directed to write down the contents of written or pictorial stimuli. The results failed to validate FC as a method of communication for any participant or facilitator. An analysis of the messages produced under the FC condition revealed a large degree of facilitator influence on the content of the mess…

MalekehitysvammaisuusAdolescentkehitysvammatfasilitoitu kommunikaatioDevelopmental psychologyCommunication Aids for DisabledSpeech and HearingautismiIntellectual DisabilitymedicineHumansta516Autistic DisorderFacilitated communicationChildSmall cityCommunicationRehabilitationReproducibility of Resultsmedicine.diseaseAuthorshipTest (assessment)Writing skillsPictorial stimuliAugmentative and alternative communicationfacilitated communicationFacilitatorAutismFemalePsychologyAugmentative and Alternative Communication
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The temporal association between executive function and life-space mobility in old age

2018

Background Life-space mobility, an indicator of community mobility, describes person’s movements in terms of the distance from home, the frequency of movement, and the need of assistance for movement. Executive function (EF) is a higher-order cognitive function that supervises motor control and plays a key role in a person’s ability to function independently. Cognitive impairment often co-occurs with restricted life-space mobility; however, the direction of the longitudinal associations between EF and life-space mobility is unclear. The aim of this study was to investigate the temporal associations between EF and life-space mobility among community-dwelling older people. Methods One hundred…

Malekognitiiviset taidotAgingTrail Making TestPoison controlliikuntaOccupational safety and health03 medical and health sciencesDisability EvaluationExecutive Function0302 clinical medicinePredictive Value of TestsInjury preventionActivities of Daily Livingmotor controlMedicineHumansCognitive Dysfunction030212 general & internal medicineCognitive declineMobility Limitation10. No inequalityGeriatric AssessmentAgedAged 80 and overSuccessful agingbusiness.industrycognitive agingHuman factors and ergonomicsCognitionsuccessful agingta3142ikääntyminenQuality of LifeFemaleIndependent LivingliikkuminenGeriatrics and Gerontologybusiness030217 neurology & neurosurgeryDemographyFollow-Up Studies
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Promoting mobility after hip fracture (ProMo): study protocol and selected baseline results of a year-long randomized controlled trial among communit…

2011

Abstract Background To cope at their homes, community-dwelling older people surviving a hip fracture need a sufficient amount of functional ability and mobility. There is a lack of evidence on the best practices supporting recovery after hip fracture. The purpose of this article is to describe the design, intervention and demographic baseline results of a study investigating the effects of a rehabilitation program aiming to restore mobility and functional capacity among community-dwelling participants after hip fracture. Methods/Design Population-based sample of over 60-year-old community-dwelling men and women operated for hip fracture (n = 81, mean age 79 years, 78% were women) participat…

Maleliikkumiskykymedicine.medical_specialtyAgingTime Factorslcsh:Diseases of the musculoskeletal systemReferralmedicine.medical_treatmentPopulationlaw.inventionStudy ProtocolDisability EvaluationRheumatologyRandomized controlled triallawIntervention (counseling)MedicineHumansOrthopedics and Sports MedicineFunctional abilityRange of Motion ArticulareducationFinlandPhysical Therapy ModalitiesAgedAged 80 and overeducation.field_of_studyHip fractureRehabilitationbusiness.industryHip FracturesAge FactorsRecovery of FunctionMiddle Agedmedicine.diseaseBiomechanical PhenomenaikääntyminenTreatment OutcomeMobility LimitationResearch DesignPhysical therapyPatient ComplianceFemaleHip JointlonkkamurtumaIndependent Livinglcsh:RC925-935businessProgram EvaluationBMC Musculoskeletal Disorders
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Do fatty acids help in overcoming reading difficulties? A double-blind, placebo-controlled study of the effects of eicosapentaenoic acid and carnosin…

2008

Background  There are claims that dietary supplementation of unsaturated fatty acids could help children with dyslexia to overcome their reading problems. However, these claims have not yet been empirically tested. Methods  This study was designed to test whether dietary supplementation was superior to placebo in treating reading, spelling or other reading-related skills of children with dyslexia. The experimental group (eicosapentaenoic acid, EPA, n = 30) ate dietary supplements and the control group (placebo, n = 31) placebos during the 90-day treatment period. The supplements contained omega-3 fatty acid (ethyl-EPA, 500 mg/day) and carnosine (400 mg/day). The groups were matched for read…

Malemedia_common.quotation_subjectPlacebo-controlled studyPlaceboDevelopmental psychologyDyslexiaDouble-Blind MethodReading (process)Developmental and Educational PsychologymedicineHumansChildFinlandmedia_commonchemistry.chemical_classificationCarnosinePublic Health Environmental and Occupational HealthDyslexiaFatty acidmedicine.diseaseEicosapentaenoic acidCombined Modality TherapySpellingTreatment OutcomechemistryEicosapentaenoic AcidCase-Control StudiesPediatrics Perinatology and Child HealthLearning disabilityDietary SupplementsFemalemedicine.symptomPsychologyClinical psychologyChild: care, health and development
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Chronic back pain in patients with rheumatoid arthritis and in a control population: prevalence and disability--a 5-year follow-up.

2011

Objectives. To determine the prevalence of chronic back pain and its changes over 5 years in patients with RA compared with community controls and to evaluate the influence of chronic back pain in functional capacity, general pain and global health. Methods. The prevalence of chronic back pain in 1076 patients with RA and in 1491 community controls was evaluated using a mailed questionnaire, which also queried the functional capacity on the HAQ, and general pain and global health on visual analogue scales. Results. Chronic back pain was more frequent in the general population than in patients with RA: 19% of patients with RA and 25% of controls reported chronic back pain (P < 0.001). After …

Malemedicine.medical_specialty5 year follow upHealth StatusPopulationAge and sexPopulation controlArthritis RheumatoidDisability EvaluationRheumatologySurveys and QuestionnairesBack painGlobal healthPrevalenceMedicineHumansPharmacology (medical)In patienteducationFinlandAgedPain Measurementeducation.field_of_studybusiness.industryMiddle Agedmedicine.diseaseBack PainRheumatoid arthritisCase-Control StudiesChronic DiseasePhysical therapyFemalemedicine.symptombusinesshuman activitiesFollow-Up StudiesRheumatology (Oxford, England)
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Self-Reported Hearing Status Is Associated with Lower Limb Physical Performance, Perceived Mobility, and Activities of Daily Living in Older Communit…

2015

BACKGROUND: Poor hearing is common in older adults and it may have negative consequences which extend beyond communication. OBJECTIVES: To explore the associations of self-reported hearing problems with physical performance and self-reported difficulties in mobility and activities of daily living (ADL) in community-dwelling older adults. DESIGN: Cross-sectional cohort study SETTING: Community PARTICIPANTS: 848 men and women aged 75-90 years MEASUREMENTS: Structured face-to-face interviews to assess perceived hearing problems in the presence of noise, mobility difficulties (moving indoors, stair-climbing, 0.5 km walk and 2 km walk) and difficulties in ADLs and instrumental ADLs. The Short Ph…

Malemedicine.medical_specialtyActivities of daily livingWalkingMotor ActivityLower limbCohort StudiesDisability Evaluation03 medical and health sciences0302 clinical medicineActivities of Daily LivingOdds Ratioactivity of daily livingHumansMedicine030212 general & internal medicineCognitive skillMobility LimitationRisk factorHearing Lossta315Geriatric AssessmentPostural BalanceFinlandAgedAged 80 and overbusiness.industryagingta3141Odds ratiophysical performancemobilityCross-Sectional StudiesliikkuvuusPhysical performancehearingPhysical therapyFemaleSelf ReportGeriatrics and Gerontologybusinesshuman activities030217 neurology & neurosurgeryHearing.statusCohort studyJournal of the American Geriatrics Society
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Two-year changes in quality of life in elderly patients with low-energy hip fractures. A case-control study

2010

Background The long-term effect of hip fracture on health-related quality of life (HRQOL) and global quality of life (GQOL) has not been thoroughly studied in prospective case-control studies. Aims a) to explore whether patients with low-energy hip fracture regain their pre-fracture levels in HRQOL and GQOL compared with changes in age- and sex-matched controls over a two year period; b) to identify predictors of changes in HRQOL and GQOL after two years. Methods We examined 61 patients (mean age = 74 years, SD = 10) and 61 matched controls (mean age = 73 years, SD = 8). The Short Form 36 assessed HRQOL and the Quality of Life Scale assessed GQOL. Paired samples t tests and multiple linear …

Malemedicine.medical_specialtyActivities of daily livinglcsh:Diseases of the musculoskeletal systemSports medicinemedicine.medical_treatmentTimeDisability EvaluationPhysical medicine and rehabilitationRheumatologyQuality of lifeActivities of Daily LivingOutcome Assessment Health CareEpidemiologyHumansMedicineOrthopedics and Sports MedicineProspective StudiesProspective cohort studyAgedAged 80 and overHip fractureRehabilitationHip Fracturesbusiness.industryVDP::Medical disciplines: 700::Clinical medical disciplines: 750Recovery of FunctionMiddle Agedmedicine.diseaseCase-Control StudiesOrthopedic surgeryQuality of LifePhysical therapyFemalelcsh:RC925-935businessFollow-Up StudiesResearch ArticleBMC Musculoskeletal Disorders
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Determining cut-off points in functional assessment scales in stroke

2015

[EN] BACKGROUND: A wide variety of well-validated assessment scales of functioning and disability have been developed for stroke population. However, these instruments have limitations in their interpretation. Therefore, determining cut-off points for their categorization becomes necessary. OBJECTIVES: To determine cut-off points for the BI, FIM and FAM scales to differentiate clinical disability categories and to establish the relationship between mRS and DOS scales. METHODS: One hundred and six adults with ischemic or haemorrhagic stroke were mainly recruited from a rehabilitation facility (Hospitales Nisa, Valencia, Spain). RESULTS: A high correlation was observed between the DOS and mRS…

Malemedicine.medical_specialtyActivities of daily livingmedicine.medical_treatmentPopulationESTADISTICA E INVESTIGACION OPERATIVAPhysical Therapy Sports Therapy and RehabilitationHaemorrhagic strokeCorrelationDisability EvaluationmedicineHumansClinical evaluationeducationStrokeAgededucation.field_of_studyRehabilitationDisabilityRehabilitationStroke RehabilitationActivities of daily livingmedicine.diseaseStrokeCategorizationPhysical therapyFemaleNeurology (clinical)Cut-offPsychology
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Combining Disability and Frailty in an Integrated Scale for Prognostic Assessment After Acute Coronary Syndrome

2018

Malemedicine.medical_specialtyAcute coronary syndromeScale (ratio)Risk AssessmentSeverity of Illness IndexCohort StudiesDisability EvaluationPredictive Value of TestsCause of DeathmedicineHumansHospital MortalityAcute Coronary SyndromeGeriatric AssessmentAgedAged 80 and overFrailtybusiness.industryGeneral MedicinePrognosismedicine.diseaseSurvival AnalysisHospitalizationSpainPhysical therapyFemalebusinessRevista Española de Cardiología (English Edition)
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