6533b7d0fe1ef96bd125ae47

RESEARCH PRODUCT

Do fatty acids help in overcoming reading difficulties? A double-blind, placebo-controlled study of the effects of eicosapentaenoic acid and carnosine supplementation on children with dyslexia.

Leila KairaluomaMikko AroTimo AhonenJari WesterholmVesa Närhi

subject

Malemedia_common.quotation_subjectPlacebo-controlled studyPlaceboDevelopmental psychologyDyslexiaDouble-Blind MethodReading (process)Developmental and Educational PsychologymedicineHumansChildFinlandmedia_commonchemistry.chemical_classificationCarnosinePublic Health Environmental and Occupational HealthDyslexiaFatty acidmedicine.diseaseEicosapentaenoic acidCombined Modality TherapySpellingTreatment OutcomechemistryEicosapentaenoic AcidCase-Control StudiesPediatrics Perinatology and Child HealthLearning disabilityDietary SupplementsFemalemedicine.symptomPsychologyClinical psychology

description

Background  There are claims that dietary supplementation of unsaturated fatty acids could help children with dyslexia to overcome their reading problems. However, these claims have not yet been empirically tested. Methods  This study was designed to test whether dietary supplementation was superior to placebo in treating reading, spelling or other reading-related skills of children with dyslexia. The experimental group (eicosapentaenoic acid, EPA, n = 30) ate dietary supplements and the control group (placebo, n = 31) placebos during the 90-day treatment period. The supplements contained omega-3 fatty acid (ethyl-EPA, 500 mg/day) and carnosine (400 mg/day). The groups were matched for reading skills, grade, gender, attention problems, intelligence and amount of special education. The literacy-related skills of the two groups were assessed before and after the treatment period. Results  No group differences were observed between EPA and placebo in measures of reading accuracy or speed, spelling, decoding fluency, arithmetical skills, reading-related language skills, attention or behavioural problems. Conclusion  The present findings do not support the hypothesis that omega-3 fatty acid (ethyl-EPA) or carnosine has a role in the treatment of reading and spelling problems in children with dyslexia.

10.1111/j.1365-2214.2008.00881.xhttps://pubmed.ncbi.nlm.nih.gov/18991979