Search results for "distress"
showing 10 items of 555 documents
Strategy of Treatment in the Advanced Stages — Round Table Report
1983
Although cancer of the prostate is completely preventable by castration before puberty, prevention at such a price is obviously out of the question. Equally, in later life, it is necessary to weigh up the cost to the patient, in terms of quality of life, of any slight extension of its duration. Denis reminded us that in autumn it is not the length of days but their freedom from distress which should be our primary concern.
Nanomedicine: A Diagnostic and Therapeutic Approach to COVID-19
2021
The SARS-CoV-2 virus is causing devastating morbidity and mortality worldwide. Nanomedicine approaches have a high potential to enhance conventional diagnostics, drugs and vaccines. In fact, lipid nanoparticle/mRNA vaccines are already widely used to protect from COVID-19. In this review, we present an overview of the taxonomy, structure, variants of concern, epidemiology, pathophysiology and detection methods of SARS-CoV-2. The efforts of repurposing, tailoring, and adapting pre-existing medications to battle COVID-19 and the state of vaccine developments are presented. Next, we discuss the broad concepts and limitations of how nanomedicine could address the COVID-19 threat. Nanomaterials …
Flexibly Scheduled Early Childhood Education and Care: Finnish Mothers’ and Educators’ Perceptions on Young Children’s Experiences and Child-Responsi…
2018
The study explores Finnish mothers' and educators' perceptions on young children's experiences and child-responsive practices related to flexibly-scheduled early childhood education and care (ECEC). Data were gathered by ethnography-based interviews with mothers and educators of oneto three-year-old children attending this form of ECEC and qualitatively analysed using the method of inductive content analysis. According to the interviewees, young children experienced a multitude of feelings related to flexibly-scheduled ECEC, ranging from the undesirable, such as strain, distress and confusion, to the desirable, such as comfort, satisfaction and understanding. The children's feelings were as…
Financial Fragility and Distress Propagation in a Network of Regions
2012
Building on previous works on business fluctuations, we model the propagation of financial distress in a network of regions, each populated by heterogeneous interacting firms and banks. In order to diversify risk, firm sell goods outside their own region and borrow from banks located there. However, this results in ties across regions which propagate financial distress across regional borders. We investigate how the average level of economic integration affects the probability of both individual and systemic failures. We find that the benefit of greater diversification is eventually offset by the effect of financial acceleration and contagion. In particular, beyond a certain level of integr…
Macro-uncertainty and financial stress spillovers in the Eurozone
2020
Abstract This paper studies macro-uncertainty and financial distress spillovers within the Eurozone. We propose a novel methodology to derive the indices of spillovers, by using a Global Vector autoregressive model fitted to data sampled at mixed-frequencies. We find that macro-uncertainty and financial stress are relatively disconnected in the Eurozone. We also show that connectedness between core and periphery Eurozone countries mainly operates through financial stress and it decreases since the outbreak of the Eurozone sovereign debt crisis (with an increasing role played by peripheral countries). As a result, investors and policymakers should monitor separately macro-uncertainty and fin…
Bank fragility and contagion: Evidence from the bank CDS market
2016
Understanding how contagion works among financial institutions is a top priority for regulators and policy makers who aim to foster financial stability and to prevent financial crises. Using bank credit default swap (CDS) data, we provide a framework for the evaluation of contagion among banks in different countries and regions during a period of prolonged financial distress. We measure contagion in terms of return spillovers, following a Generalized VAR (GVAR) approach. In addition, we propose an innovative framework to distinguish between two types of contagion: systematic (linked to global factors), and idiosyncratic (linked to bank specific factors). We find evidence of both types of co…
The euro area sovereign debt crisis: Can contagion spread from the periphery to the core?
2014
Abstract We examine the determinants of joint default risk of euro area countries during 2007–2011. To accomplish this, we recover joint default probabilities from individual CDS contracts. In contrast to earlier theoretical studies, we find that financial linkages are an active contagion transmission channel only in the case of the troubled periphery euro area economies. During the current sovereign debt crisis, real economy linkages play a more important role in transmitting shocks from the euro area periphery towards its core. Countries that have stronger trade interconnections with troubled economies tend to have a higher expected joint default risk.
Economic value, competition and financial distress in the european banking system
2012
Abstract In this paper we examine the impact of a large number of factors at the bank level (liquidity and credit risks, asset size, income diversification and market power), at the industry level (banking concentration) and macro-level (real GDP growth) on bank financial distress using an unbalanced panel of 308 European commercial banks between 1996 and 2009. The observations falling below a given threshold of the empirical distribution of the Shareholder Value Ratio proxy bank financial distress. We employ a panel probit regression and, given the presence of overlapping data giving rise to residual autocorrelation, we use the Bertschek and Lechner (1998) robust estimator of the covarianc…
How does fiscal policy react to wealth composition and asset prices?
2012
Prova tipográfica
Revisiting bank failure in the United States: a fuzzy-set analysis
2020
Past financial crises have illustrated the importance of recognising the combinations of factors that can cause financial distress in the banking industry. Accordingly, this study uses fuzzy-set qualitative comparative analysis (fsQCA) to identify the combinations of factors that lead to bank failure. The data consist of 30 annual financial ratio series for 156 U.S. banks over a 15-year period (2001–2015). Identifying combinations of conditions that can produce bank failure is crucial to help regulators and bank managers. The fsQCA presented in this paper sheds light on the relationships between combinations of conditions and bank failure, providing a solution comprising two sufficient and …