Search results for "double"
showing 10 items of 2879 documents
Extensions of the standard model scalar sector and constraints from ccolliders and cosmology
2013
In this thesis we study the Higgs sector of the Standard Model and compare it to the latest data from the LHC and Tevatron experiments. Then we consider two extensions of the Higgs sector. First we extend the Standard Model Higgs sector with one real SU(2) singlet and then we consider two-Higgs- doublet model and extend also it with one real singlet. In both extensions the singlet scalar is considered as a potential dark matter candidate. We find that the parameter space of the so called two-Higgs-doublet-inert-singlet model includes regions which could provide a dark matter candidate which constitutes significant amount of the total dark matter mass density.
Ordinary Muon Capture on 136Ba : Comparative Study Using the Shell Model and pnQRPA
2023
In this work, we present a study of ordinary muon capture (OMC) on 136136Ba, the daughter nucleus of 136136Xe double beta decay (DBD). The OMC rates at low-lying nuclear states (below 1 MeV of excitation energy) in 136136Cs are assessed by using both the interacting shell model (ISM) and proton–neutron quasiparticle random-phase approximation (pnQRPA). We also add chiral two-body (2BC) meson-exchange currents and use an exact Dirac wave function for the captured s-orbital muon. OMC can be viewed as a complementary probe of the wave functions in 136136Cs, the intermediate nucleus of the 136136Xe DBD. At the same time, OMC can be considered a powerful probe of the effective values of weak axi…
Apparent and quantitative loss of fatty acids and triacylglycerols at frying temperatures
2012
[EN]: Olive and sunflower oils were heated at 180 °C for 5, 10 and 15 hours with the aim of defining the changes in the contents of fatty acid methyl esters (FAME) and triacylglycerols (TAG) under frying conditions. Differences between apparent and real loss of FAME or TAG are defined for an adequate interpretation of the changes taking place at high temperature. Such differences depend on the expression of the results and frequently result in erroneous conclusions. Results showed that from the normalized composition it could be deduced that only the most unsaturated FAME (C18:2) or TAG containing it was significantly altered. However, quantitative data indicated that all the unsaturated FA…
Experimental and theoretical studies on corals. I. Toward understanding the origin of color in precious red corals from Raman and IR spectroscopies a…
2010
An attempt to explain the origin of the vivid red color in precious pink and red corals was undertaken. Raman and IR spectroscopies were applied to characterize white, pink and red corals. The position of the Raman signal near 1500 cm−1 of some corals and pearls was associated by several authors with the presence of the mixture of all‐trans‐polyenic pigments, containing 6–16 conjugated CC bonds or β‐carotenoids. This hypothesis was examined theoretically by performing extensive B3LYP‐DFT calculations of vibrational spectra of the model polyenic compounds. The B3LYP/6‐311++G** predicted positions of the dominating Raman mode depend on the number of CC units (Cn parameter) and can be accura…
Data from: Quantitative PCR primer design affects quantification of dsRNA-mediated gene knockdown
2020
RNA interference (RNAi) is a powerful tool for studying functions of candidate genes in both model and non-model organisms and a promising technique for therapeutic applications. Successful application of this technique relies on the accuracy and reliability of methods used to quantify gene knockdown. With the limitation in the availability of antibodies for detecting proteins, quantitative PCR (qPCR) remains the preferred method for quantifying target gene knockdown after dsRNA treatment . We evaluated how qPCR primer binding site and target gene expression levels affect quantification of intact mRNA transcripts following dsRNA-mediated RNAi. The use of primer pairs targeting the mRNA sequ…
Estar al otro lado de la mesa. Profesionales de los servicios públicos de empleo ante los dilemas de la activación laboral
2019
Under the paradigm of activation, the Public Employment Services has been reshaped by two levels of contractualization. On one hand, the collaboration of the administration with a network of agents on the programme scheme that make up the active policies of employment. On the other hand, the unemployed person?s access to a compartmentalized offer of services and individually taking responsibility for finding work. This double contractualization reveals redefinition of lowering public responsibility faced with the problem of unemployment that this activation supposes. This paper analyses how this redesign has an impact on how professionals serve the unemployed population. This lays bare, in …
Enhancing Metastability by Dissipation and Driving in an Asymmetric Bistable Quantum System.
2018
The stabilizing effect of quantum fluctuations on the escape process and the relaxation dynamics from a quantum metastable state are investigated. Specifically, the quantum dynamics of a multilevel bistable system coupled to a bosonic Ohmic thermal bath in strong dissipation regime is analyzed. The study is performed by a non-perturbative method based on the real-time path integral approach of the Feynman-Vernon influence functional. We consider a strongly asymmetric double well potential with and without a monochromatic external driving, and with an out-of-equilibrium initial condition. In the absence of driving we observe a nonmonotonic behavior of the escape time from the metastable regi…
Comparison of Microscopic Interacting Boson Model and Quasiparticle Random Phase Approximation 0νββ Decay Nuclear Matrix Elements
2021
The fundamental nature of the neutrino is presently a subject of great interest. A way to access the absolute mass scale and the fundamental nature of the neutrino is to utilize the atomic nuclei through their rare decays, the neutrinoless double beta (0νββ) decay in particular. The experimentally measurable observable is the half-life of the decay, which can be factorized to consist of phase space factor, axial vector coupling constant, nuclear matrix element, and function containing physics beyond the standard model. Thus reliable description of nuclear matrix element is of crucial importance in order to extract information governed by the function containing physics beyond the standard m…
Inhibition of Rac1 signaling by lovastatin protects against anthracycline-induced cardiac toxicity
2011
Normal tissue damage limits the efficacy of anticancer therapy. For anthracyclines, the clinically most relevant adverse effect is cardiotoxicity. The mechanisms involved are poorly understood and putative cardioprotectants are controversially discussed. Here, we show that the lipid-lowering drug lovastatin protects rat H9c2 cardiomyoblasts from doxorubicin in vitro. Protection by lovastatin is related to inhibition of the Ras-homologous GTPase Rac1. It rests on a reduced formation of DNA double-strand breaks, resulting from the inhibition of topoisomerase II by doxorubicin. Doxorubicin transport and reactive oxygen species are not involved. Protection by lovastatin was confirmed in vivo. I…
Rac1 and PAK1 are upstream of IKK-ε and TBK-1 in the viral activation of interferon regulatory factor-3
2004
The anti-viral type I interferon (IFN) response is initiated by the immediate induction of IFN beta, which is mainly controlled by the IFN-regulatory factor-3 (IRF-3). The signaling pathways mediating viral IRF-3 activation are only poorly defined. We show that the Rho GTPase Rac1 is activated upon virus infection and controls IRF-3 phosphorylation and activity. Inhibition of Rac1 leads to reduced IFN beta promoter activity and to enhanced virus production. As a downstream mediator of Rac signaling towards IRF-3, we have identified the kinase p21-activated kinase (PAK1). Furthermore, both Rac1 and PAK1 regulate the recently described IRF-3 activators, I kappa B kinase- and TANK-binding kina…