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showing 10 items of 74798 documents

The Greenland shark Somniosus microcephalus—Hemoglobins and ligand-binding properties

2017

A large amount of data is currently available on the adaptive mechanisms of polar bony fish hemoglobins, but structural information on those of cartilaginous species is scarce. This study presents the first characterisation of the hemoglobin system of one of the longest-living vertebrate species (392 +/- 120 years), the Arctic shark Somniosus microcephalus. Three major hemoglobins are found in its red blood cells and are made of two copies of the same a globin combined with two copies of three very similar beta subunits. The three hemoglobins show very similar oxygenation and carbonylation properties, which are unaffected by urea, a very important compound in marine elasmobranch physiology.…

---0301 basic medicinegenetic structuresProtein ConformationGreenlandlcsh:MedicineRESONANCE RAMAN-SPECTRAHETERODONTUS-PORTUSJACKSONISpectrum Analysis RamanBiochemistrychemistry.chemical_compoundHemoglobinsProtein structureAMINO-ACID SEQUENCEAnimal CellsSequence Analysis ProteinRed Blood CellsUreaNOTOTHENIOID FISHESPost-Translational Modificationlcsh:ScienceHemeChondrichthyesMultidisciplinarybiologyChemistryOrganic CompoundsChemical ReactionsVertebrateEukaryotaMOLECULAR ADAPTATIONSMicrocephalusGlobinsChemistryBiochemistryOptical EquipmentVertebratesPhysical SciencesEngineering and TechnologyCellular TypesResearch ArticleEnvironmental MonitoringProtein BindingQUATERNARY STRUCTURESAllosteric regulationEquipmentSTRETCHING FREQUENCIESHeme03 medical and health sciencesOXYGEN-BINDINGbiology.animalAnimals14. Life underwaterGlobinHemoglobinPhotolysisBlood Cells030102 biochemistry & molecular biologyLaserslcsh:ROrganic ChemistryOrganismsChemical CompoundsBiology and Life SciencesProteinsxxxCell Biologybiology.organism_classificationCARTILAGINOUS FISHOxygen030104 developmental biologySomniosusFishSharkslcsh:QHemoglobinProtein MultimerizationELASMOBRANCH HEMOGLOBINElasmobranchiiPLoS ONE
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Prevalence and characteristics of antidepressant drug prescriptions in older Italian patients.

2012

ABSTRACTBackground: During last few decades, the proportion of elderly persons prescribed with antidepressants for the treatment of depression and anxiety has increased. The aim of this study was to evaluate prevalence of antidepressant prescription and related factors in elderly in-patients, as well as the consistency between prescription of antidepressants and specific diagnoses requiring these medications.Methods: Thirty-four internal medicine and four geriatric wards in Italy participated in the Registro Politerapie SIMI–REPOSI study during 2008. In all, 1,155 in-patients, 65 years or older, were enrolled. Prevalence of the use of antidepressants was calculated at both admission and dis…

---DrugMalemedicine.medical_specialtyMultivariate analysisSettore MED/09 - Medicina Internaantidepressants; prescription; elderly; hospitalization; dementiamedia_common.quotation_subjectLogistic regressionelderlySex FactorsInternal medicinemedicinePrevalenceantidepressant drugsDementiaHumansMedical prescriptionPractice Patterns Physicians'PsychiatryDepression (differential diagnoses)media_commonAgedprescriptionantidepressantbusiness.industryDepressionAge Factorsmedicine.diseaseSettore MED/45 - Scienze Infermieristiche Generali Cliniche E PediatricheAntidepressive AgentsPsychiatry and Mental healthClinical PsychologyLogistic Models---; elderly; antidepressant drugs; PrevalenceItalyAnxietyAntidepressantDementiaFemaleGeriatrics and Gerontologymedicine.symptombusinessGerontologyhospitalizationInternational psychogeriatrics
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Association between clusters of diseases and polypharmacy in hospitalized elderly patients: results from the REPOSI study.

2011

BACKGROUND: Although the association between multimorbidity and polypharmacy has been clearly documented, no study has analyzed whether or not specific combinations of diseases influence the prescription of polypharmacy in older persons. We assessed which clusters of diseases are associated with polypharmacy in acute-care elderly in-patients. METHODS: This cross-sectional study was held in 38 Italian internal medicine and geriatric wards participating in the Registro Politerapie SIMI (REPOSI) study during 2008. The study sample included 1155 in-patients aged 65 years or older. Clusters of diseases, defined as two or more co-occurring specific chronic diseases, were identified using the odds…

---Lung DiseasesMaleSettore MED/09 - Medicina InternaCross-sectional studyGastrointestinal DiseasesComorbidityRisk FactorsNeoplasmsPrevalenceCluster AnalysisHospitalized elderlyclustersGeriatricsAged 80 and overCOPDREPOSISettore MED/45 - Scienze Infermieristiche Generali Cliniche E PediatricheHospitalization---; clusters; polypharmacy; REPOSI; elderlyCardiovascular DiseasesFemalemedicine.medical_specialtyEndocrine System DiseaseselderlyCluster of diseasesInternal medicineDiabetes mellitusmedicineDiabetes MellitusInternal MedicineMultimorbidityHumansCluster of diseases; Hospitalized elderly; PolypharmacyAgedPolypharmacybusiness.industryPolypharmacy Cluster of diseases Hospitalized elderlyOdds ratiomedicine.diseaseComorbidityCross-Sectional StudiesLogistic ModelsGeriatricsPhysical therapyPolypharmacyDementiaMorbiditybusinessEuropean journal of internal medicine
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Performance of PSI, CURB-65, and SCAP scores in predicting the outcome of patients with community-acquired and healthcare-associated pneumonia

2011

The objective was to compare three score systems, pneumonia severity index (PSI), the Confusion-Urea-Respiratory Rate-Blood pressure-65 (CURB-65), and severe community-acquired pneumonia (SCAP), for prediction of the outcomes in a cohort of patients with community-acquired (CAP) and healthcare-associated pneumonia (HCAP). Large multi-center, prospective, observational study was conducted in 55 hospitals. HCAP patients were included in the high classes of CURB-65, PSI and SCAP scores have a mortality rate higher than that of CAP patients. HCAP patients included in the low class of the three severity rules have a significantly higher incidence of adverse events, including development of septi…

---medicine.medical_specialtySettore MED/09 - Medicina Internacommunity-acquired pneumoniaPneumonia severity indexBlood PressureSettore MED/10 - Malattie Dell'Apparato RespiratorioCommunity-acquired pneumonia Healthcare-associated pneumonia PSI CURB 65Severity of Illness IndexCommunity-acquired pneumoniaRespiratory RatePredictive Value of TestsInternal medicineCURB 65Severity of illnessInternal MedicinePneumonia BacterialMedicineHumansUreaPSIProspective StudiesIntensive care medicineProspective cohort studyConfusion---; community-acquired pneumonia; Healthcare-associated pneumonia; PSI; CURB 65Cross Infectioncommunity-acquired pneumonia; psi; healthcare-associated pneumonia; curb 65business.industryMortality ratemedicine.diseasePrognosisCURB-65Settore MED/45 - Scienze Infermieristiche Generali Cliniche E PediatricheHealthcare-associated pneumoniaCommunity-Acquired InfectionsPneumoniaCohortEmergency Medicinebusiness
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Satvara izstrāde vienotai lietotāja ievades klienta un servera puses validācijai

2016

Lietotāja ievades validācija ir pašsaprotams process jebkurā nopietnā sistēmā. Slikti dati un izvairīšanās no to apstrādes var novest pie drošības riskiem, negaidītas sistēmas darbības vai sliktas pieredzes lietojot sistēmu. Parasti sistēmām servera puses un klienta puses validācijas tiek veidotas atsevišķi, taču uzdevumi bieži vien pārklājas. Kā bakalaura darba mērķis tika izvirzīts izpētīt klienta un servera puses validācijas risinājumus, atrast kopīgās raksturīpašības un izveidot sistēmu, kas ļauj vienuviet pārvaldīt izmaiņas, nodrošināt kļūdu ziņojumu tulkojumus, neatkārtot darbības, kas jau veiktas citā solī. Bakalaura darbā izvirzītā hipotēze – vienota satvara izstrāde klienta un serv…

.NETLietotāja ievades validācijaDatorzinātneDRYkļūdu ziņojumu tulkošanaAngularJS
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Resursu vadības sistēmas “G-VEDIS” moduļa “ALGAS” papildināšana ar pārskatu par izmaksām nerezidentiem un sagatavošanu iesniegšanai Valsts ieņēmumu d…

2019

Kvalifikācijas darba ietvaros tika papildināta resursu vadības sistēmas “G-VEDIS” moduļa “ALGAS” funkcionalitāte. Izstrādātais papildinājums resursu vadības sistēmas lietotājam nodrošina iespēju saglabāt informāciju par nerezidentu, veikt kopsavilkumu par nerezidenta gūtajiem ienākumiem un samaksātajiem nodokļiem taksācijas periodā. Nodrošināt pārvaldību EDS dokumentam un iegūt PDF un XLS dokumentus, kā arī XML dokumentu, kuru var nodot VID EDS sistēmai. Risinājums tika izstrādāts, izmantojot PL/SQL Developer, Microsoft Visual Studio rīkus, .Net, .NET MVC.

.NETPL/SQL DeveloperDatorzinātneresursu vadības sistēmaresource management systemMicrosoft Visual Studio
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¿Cómo afecta la innovación en la satisfacción y la lealtad hacia el establecimiento minorista?

2021

Resumen En el presente estudio, se examinó el concepto de innovación en el sector minorista y se definieron sus relaciones con otras variables, como la satisfacción y la lealtad, tradicionalmente vinculadas con el establecimiento minorista. Para lograr los objetivos planteados, se delimitó un modelo teórico sustentado en la literatura, que se contrastó mediante un estudio empírico utilizando un cuestionario estructurado ad hoc aplicado a una muestra de 510 clientes de establecimientos de alimentación. El análisis de los datos se desarrolló mediante la técnica de regresión por mínimos cuadrados parciales. Los resultados permiten proponer un conjunto de recomendaciones para la gestión, fundam…

//id.loc.gov/authorities/subjects/sh85078691 [http]HF5001-6182Strategy and ManagementSatisfaction//vocabularies.unesco.org/thesaurus/concept1545 [http]//vocabularies.unesco.org/thesaurus/concept4566 [http]LoyaltyConsumer protectionAdvertisingManagement of Technology and InnovationCambio tecnológicosatisfaçãoBusinessInnovación de marketing//vocabularies.unesco.org/thesaurus/concept6424 [http]MarketingLealtadM30 Generalrelational innovationConductainovação de marketinginnovación de marketingInnovaciones tecnológicasmarketing innovationproduct innovationinovação de produtoInnovación en productoTime to market (New products)Viral marketingEconomics and EconometricsConductlealdade//id.loc.gov/authorities/subjects/sh2003011474 [.http]PublicidadSistema de valoresinovação relacional//vocabularies.unesco.org/thesaurus/concept1532 [http]Innovación relacionalinnovación relacionalNormas de conductainnovación en producto//vocabularies.unesco.org/thesaurus/concept403 [http]SatisfacciónMercadeoProtección del consumidorValue systemsBusiness and International ManagementlealtadMercadeo viral//id.loc.gov/authorities/subjects/sh85133143 [http]Technological changeStandards of ConductsatisfacciónTiempo en el mercado (Productos nuevos)//id.loc.gov/authorities/subjects/sh85117681 [http]//id.loc.gov/authorities/subjects/sh94006567 [http]Technological innovationsFinance
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Due note etimologiche circostanziali circa il Ms.II.D.54 (BNN) attribuito a Baffi

2019

Within the investigations on the attribution of some manuscripts to the famous philologist P. Baffi and now kept at the National Library of Naples (BNN), this brief contribution investigates in detail some of the passages contained in Ms.II.D.54 (f. 234r et f. 325r), in order to understand its meaning and to evaluate and validate its attributing hypotheses.

//pages.uv.es/SPhV/cas/numero21.wiki [Etymological notes ? Baffi ? Ms.II.D.54 (BNN) 5 21 https]UNESCO::CIENCIAS DE LAS ARTES Y LAS LETRASin order to understand its meaning and to evaluate and validate its attributing hypotheses. Note etimologiche ? Baffi ? Ms.II.D.54 (BNN)this brief contribution investigates in detail some of the passages contained in Ms.II.D.54 (f. 234r et f. 325r):CIENCIAS DE LAS ARTES Y LAS LETRAS [UNESCO]Nikola Within the investigations on the attribution of some manuscripts to the famous philologist P. Baffi and now kept at the National Library of Naples (BNN)Etymological notes ? Baffi ? Ms.II.D.54 (BNN) 5 21 https://pages.uv.es/SPhV/cas/numero21.wiki1135-9560 8276 Studia philologica valentina 536436 2019 21 7225810 Due note etimologiche circostanziali circa il Ms.II.D.54 (BNN) attribuito a Baffi Bellucci
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Más allá de los dinosaurios: nuevas perspectivas para el patrimonio paleontológico de La Rioja

2018

El patrimonio paleontológico en nuestro país ha sido objeto de discusión entre científicos y legisladores desde su controvertida consideración dentro del patrimonio histórico en la Ley 16/1985, de 25 de junio, del Patrimonio Histórico Español. Así, tanto el patrimonio inmueble (yacimientos) como el mueble (ejemplares ex situ alojados en museos, colecciones y exposiciones locales) se gestionaron durante años bajo esta norma hasta su inclusión, en el año 2007, en la nueva Ley 42/2007, de 13 de diciembre, de Patrimonio Natural y Biodiversidad. Fil: García Ortiz de Landaluce, Esperanza. Universidad de la Rioja; España Fil: Díaz Martínez, Ignacio. Consejo Nacional de Investigaciones Científicas …

//purl.org/becyt/ford/1 [https]//purl.org/becyt/ford/1.5 [https]EmbryologyCell BiologyLa RiojaAnatomyPatrimonioCIENCIAS NATURALES Y EXACTASPaleontologíaCiencias de la Tierra y relacionadas con el Medio AmbienteDevelopmental Biologyrevista PH
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Propiedades Psicométricas de la Escala de Creencia en un Mundo Justo General y Personal en el Contexto Argentino

2018

El objetivo principal de este trabajo fue analizar las propiedades psicométricas de las Escalas de Creencia en un Mundo Justo General y Personal. Para tal fin, se examinó la estructura interna de ambas, testeando si evalúan un mismo constructo global o constituyen dos dimensiones diferenciadas, la consistencia interna de cada una y sus relaciones con las orientaciones religiosas. Participaron del estudio 328 estudiantes universitarios de la Ciudad Autónoma de Buenos Aires con edades entre 18 y 40 años (M = 24,1; DT = 3,88). El 36,6% eran hombres (n = 120) y el 63,4% mujeres (n = 208). Los resultados del estudio sugieren propiedades psicométricas adecuadas para ambas escalas de CMJ. Además, …

//purl.org/becyt/ford/5 [https]05 social sciencesOtras PsicologíaPsicologíaConfirmatory factor analysisCREENCIA PERSONAL EN UN MUNDO JUSTOCIENCIAS SOCIALESCREENCIA GENERAL EN UN MUNDO JUSTOCronbach's alphaJust-world hypothesisInternal consistencyRELIGIOSIDADVALIDACION0501 psychology and cognitive sciencesPsychologySocial psychology//purl.org/becyt/ford/5.1 [https]050104 developmental & child psychologyPsykhe (Santiago)
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