Search results for "edge"

Seprase-DPPIV Association and Prolyl Peptidase and Gelatinase Activities of the Protease Complex

2005

Toward completion of the Earth’s proteome: an update a decade later

2017

Protein databases are steadily growing driven by the spread of new more efficient sequencing techniques. This growth is dominated by an increase in redundancy (homologous proteins with various degrees of sequence similarity) and by the incapability to process and curate sequence entries as fast as they are created. To understand these trends and aid bioinformatic resources that might be compromised by the increasing size of the protein sequence databases, we have created a less-redundant protein data set. In parallel, we analyzed the evolution of protein sequence databases in terms of size and redundancy. While the SwissProt database has decelerated its growth mostly because of a focus on i…

A Proposed Knowledge Based Approach for Solving Proteomics Issues

2010

In this paper we present a novel knowledge-based approach that aims at helping scientists to face and resolve a large number of proteomics problem. The system architecture is based on an ontology to model the knowledge base, a reasoner that starting from the user's request and a set of rules builds the workflow of tasks to be done, and an executor that runs the algorithms and software scheduled by the reasoner. The system can interact with the user showing him intermediate results and several options in order to refine the workflow and supporting him to choose among different forks. Thanks to the presence of the knowledge base and the modularity provided by the ontology, the system can be e…

Opinion of the Patients About an Internet-Based Psychological Treatment Protocol

2015

Emotional disorders (depression and anxiety disorders) are highly prevalent. Currently, there is evidence showing the efficacy of disorder-specific cognitive-behavior therapy for emotional disorders. However, high comorbidity rates among emotional disorders have led some researchers to shift the focus to treatment strategies that might be more widely effective across these diverse conditions (transdiagnostic approach). Another important line of research in the literature is Internet-based psychotherapy. An increasing number of meta-analyses have shown the efficacy and effectiveness of Internet-based cognitive-behavior treatment protocols for emotional disorders. Nevetherless, little is know…

Teaching mechanical oscillations using an integrate curriculum

1997

Abstract A set of teaching materials dealing with harmonic oscillations was developed as part of a research project investigating the influence of different pedagogical tools on physics learning. The materials incorporate simulation software and laboratory activities associated with Teacher and Student Units. The project involved research groups at seven Italian universities and the materials have been trialled in high schools nation‐wide. This paper describes the experimental protocol for the use of these materials in pilot classes and the evaluation of student learning and teacher training results. The intervention was found to improve physics education at school praxis level and to promo…

INTERVENCIÓN PSICOSOCIAL EN ESPACIOS DE ALTA DIVERSIDAD EXPERIENCIA INTERCULTURAL Y BUENA PRAXIS

2021

espanolPsychosocial interventional approaches in reducing intergroup biases can be divided into two areas: intragroup and intergroup. The former includes work with counterstereotypespecimens (Plant et al., 2009), strategies based on cognitive dissonance (Festinger, 1957, cited in Rodriguez, 2019) and the promotion of empathy (Galinsky & Moskowitz, 2000; Stephan & Finlay, 1999). Intergroup strategies are those based on the contact hypothesis (Allport, 1954, cited in Rodriguez, 2019) and those based on the theory of social categorization or sociocognitive strategies (Tajfel & Turner, 1979). The research was ascribed to the interventional research model proposed by Rothman and Thomas (1994), c…

Some historical and epistemological remarks on itch and pruritus

2005

:  Although very common, itch is very hard to describe. It can be considered as one of the most distressing physical sensations we experience. Going back historically, old Latin and Greek writers cited it in ancient papers. So, etymology is of central importance to investigation in the field of itch, regarding the formation of a word with antique origins and different meanings. Scientists, poets, and painters for centuries tried to describe and represent itch. The study of their work reveals the development of the itch's significance. Today, a clinically relevant distinction defines pruritus and itch as two different sensations. Moreover, some terms like hyperknesis, alloknesis, atmoknesis,…

The case of homeopathy, “how to search PubMed” may be a first step

2017

Scientists’ engagement in knowledge transfer and exchange: Individual factors, variety of mechanisms and users

2018

[EN] This article aims to provide a deeper understanding of the individual factors behind scientists' involvement in a wide variety of knowledge transfer and exchange (KTE) activities. By doing so, the article addresses three major shortcomings in the literature. First, this article considers scientists' involvement in both formal and informal KTE activities. Secondly, the study focuses not only on KTE activities with the private sector, but also with other types of agents. Thirdly, the article adopts an individual approach to distinguish between three types of KTE predictors: individual capacities, training and career trajectories, and motivations. Overall, the results of the regression mo…

Exploring Students’ Metacognitive Knowledge: The Case of Integral Calculus

2020

Previous studies of integral calculus have mainly explored students&rsquo