Search results for "elder"
showing 10 items of 919 documents
Group fitness activities on elderly: an useful approch to prevent injuries and dropping out
2012
COMPULSIVE BUYING AND ELDERLY MEN: DEPRESSION, COPING STRATEGIES AND SOCIAL SUPPORT
2014
Old age is characterized by great changes that become real challenges that the person must overcome in order to effectively end his evolutionary process. Particulary, the most stressful events for the elderly are the social economic decline, the deterioration of health and the loss of loved ones. It is therefore important to consider the strategies chosen by the elderly person to cope with such tasks; these strategies, if not effective, result in a developmental failure. The objective of this research was to analyze the relantionship among geriatric depression, coping strategies and levels of problematic shopping in elderly male subjects. The research involved 120 men over 60’. The choice o…
B cell immunosenescence in the elderly and in centenarians.
2008
The elderly suffer from an increased susceptibility to infectious disease and cancer. Aging of the immune system contributes to this state of affairs due to immunosenescence. Because repeated intermittent or chronic antigen exposure may lead to lymphocyte clonal exhaustion, chronic antigenic stress plays a part in the compromised immunity of the elderly, who have accumulated a lifetime's exposure to infectious agents, autoantigens, and cancer antigens. Literature on immunosenescence has focused mainly on T cell impairment, but B cell compartment is also affected. The age-dependent B cell changes documented by the present review indicate that advanced age per se is a condition characterized …
B CELL CHANGES IN AGING
2014
The aging of the immune system is a gradual and dynamic process that modifies some immunological functions. These changes are known as “immunosenescence” that have a great impact on immune performance in late life, contributing to the decreased ability of the elderly people to respond to emerging pathogens and to the decreased responsiveness to vaccinations. It is known that the adaptive immune functions are affected in the aged. In particular, with aging, the acquired compartment of the immune system shows significant modifications in both T and B cell branches. Thus, the adaptive immune response of elderly people is qualitatively and quantitatively reduced when compared to that observed i…
B cells and immunosenescence: a focus on IgG+IgD-CD27- (DN) B cells in aged humans.
2011
Immunosenescence contributes to the decreased ability of the elderly to control infectious diseases, which is also reflected in their generally poor response to new antigens and vaccination. It is known that the T cell branch of the immune system is impaired in the elderly mainly due to expansion of memory/effector cells that renders the immune system less able to respond to new antigens. B lymphocytes are also impaired in the elderly in terms of their response to new antigens. In this paper we review recent work on B cell immunosenescence focusing our attention on memory B cells and a subset of memory B cells (namely IgG(+)IgD(-)CD27(-)) that we have demonstrated is increased in healthy el…
Triggering of Toll-like receptors in the elderly. A pilot study relevant for vaccination
2017
The impaired ability of the elderly to mount an efficient immune response after exposure to microbes or vaccines represents a major challenge in protection against pathogens in ageing. Recently studies have shown that stimulation of Toll-like receptors (TLRs), using stimulatory ligands, can enhance vaccine efficacy by a number of mechanisms, including the activation of innate immune cells and the consequent production of inflammatory cytokines.
SUCCESSFUL AGING: QUALITY AND QUANTITY
2010
GERD in the elderly: an endoscopic experience.
2013
Analyzing medical issues related to the elderly patients, particularly in the gastroenterological sphere, Gastro-Esophageal Reflux Disease (GERD) seems to be a disease that reaches an important role in terms of diagnosis and therapy, as well as adversely affect the quality of life of these “frail” patients. Comorbidities that affect these patients often lead to reduce the importance of this disease, which in fact, not infrequently, it is difficult to identify because of mild symptom picture compared to younger patients. Is important to remember that GERD, although in most cases provokes only vague dyspeptic symptoms, can also lead to serious complications, such as bleeding especially in pat…