Search results for "elektrofysiologia"
showing 10 items of 14 documents
Evaluation and extraction of mismatch negativity through exploiting temporal, spectral, time-frequency, and spatial features
2010
Irradiation of the head reduces adult hippocampal neurogenesis and impairs spatial memory, but leaves overall health intact in rats.
2021
Treatment of brain cancer, glioma, can cause cognitive impairment as a side‐effect, possibly because it disrupts the integrity of the hippocampus, a structure vital for normal memory. Radiotherapy is commonly used to treat glioma, but the effects of irradiation on the brain are still poorly understood, and other biological effects have not been extensively studied. Here we exposed healthy adult male rats to small and moderate‐dose irradiation of the head. We found no effect of irradiation on systemic inflammation, weight gain or gut microbiota diversity, although it increased the abundance of Bacteroidaceae family, namely Bacteroides genus in the gut microbiota. Irradiation had no effect on…
Electrophysiological evidence of memory-based detection of auditory regularity violations in anesthetized mice
2017
In humans, automatic change detection is reflected by an electrical brain response called mismatch negativity (MMN). Mismatch response is also elicited in mice, but it is unclear to what extent it is functionally similar to human MMN. We investigated this possible similarity by recording local field potentials from the auditory cortex of anesthetized mice. First, we tested whether the response to stimulus changes reflected the detection of regularity violations or adaptation to standard stimuli. Responses obtained from an oddball condition, where occasional changes in frequency were presented amongst of a standard sound, were compared to responses obtained from a control condition, where no…
Sympathetic nervous system synchrony: An exploratory study of its relationship with the therapeutic alliance and outcome in couple therapy.
2019
In previous research, we found that sympathetic nervous system synchrony, measured via electrodermal activity (EDA), occurs between participants at the start of couple therapy. The aim now was to test whether this synchrony changes during the therapy process, and how any changes may be related to clients' and therapists' evaluations of the working alliance, and the outcome of therapy. Twelve different couple therapy processes were analyzed (24 clients, plus 10 therapists, working in pairs; hence, 4 persons per session) using EDA concordance indices and questionnaires (Outcome Rating Scale, Session Rating Scale, and Clinical Outcomes in Routine Evaluation-Outcome Measure). EDA synchrony betw…
Hippocampal responses to electrical stimulation of the major input pathways are modulated by dentate spikes
2022
Dentate gyrus (DG) is important for pattern separation and spatial memory, and it is thought to gate information flow to the downstream hippocampal subregions. Dentate spikes (DSs) are high-amplitude, fast, positive local-field potential events taking place in the DG during immobility and sleep, and they have been connected to memory consolidation in rodents. DSs are a result of signaling from the entorhinal cortex (EC) to the DG, and they suppress firing of pyramidal cells in the CA3 and CA1. To study the effects of DSs to signaling in the hippocampal tri-synaptic loop, we electrically stimulated the afferent fibers of the DG, CA3, and CA1 in adult male Sprague–Dawley rats at different del…
Electrophysiological evidence for the effectiveness of images versus text in warnings
2023
AbstractWarning sign plays an important role in risk avoidance. Many studies have found that images are better warnings than text, while others have revealed flaws of image-only warning signs. To better understand the factors underlying the effectiveness of different types of warning signs (image only, text only, or image and text), this study adopted event-related potential technology to explore the differences at the neurocognitive level using the oddball paradigm and the Go/No-go paradigm. Together, the behavioral and electroencephalogram results showed that text-only warnings had the lowest effectiveness, but there was little difference between the image-only and image-and-text warnings…
Removing ocular artifacts from magnetoencephalographic data on naturalistic reading of continuous texts
2022
Naturalistic reading paradigms and stimuli consisting of long continuous texts are essential for characterizing the cortical basis of reading. Due to the highly dynamic nature of the reading process, electrophysiological brain imaging methods with high spatial and temporal resolution, such as magnetoencephalography (MEG), are ideal for tracking them. However, as electrophysiological recordings are sensitive to electromagnetic artifacts, data recorded during naturalistic reading is confounded by ocular artifacts. In this study, we evaluate two different pipelines for removing ocular artifacts from MEG data collected during continuous, naturalistic reading, with the focus on saccades and blin…
Auditory perceptual learning : evidence from electrophysiological recordings in rodents and humans
2018
Yllättävät muutokset äänimaailmassa viestittävät yleensä selviytymisen kannalta tärkeistä vihjeistä, joten niiden nopea ja automaattinen havaitseminen on tärkeää. Tietoinen harjoittelu mahdollistaa havainto-oppimisen ja oppimisen seurauksena hermostoon muodostuu uusia muistijälkiä. Varhaisessa kehityksessä herkkyyskauden aikana muistijälkien muodostuminen, ihmisellä erityisesti puheäänille, on automaattista, eikä siihen vaadita tietoista harjoittelua. Toisaalta perinteisesti on ajateltu, että herkkyyskauden jälkeen vain aktiivinen harjoittelu johtaa uusien muistijälkien muodostumiseen. Muutoksen havaitsemisen hermostollista perustaa voidaan tutkia mittaamalla aivojen sähköisiä jännitevastei…
How salience enhances inhibitory control : An analysis of electro-cortical mechanisms
2023
Stop-signal tasks (SSTs) combined with human electro-cortical recordings (Event-Related Potentials, ERPs) have revealed mechanisms associated with successful stopping (relative to failed), presumably contributing to inhibitory control. The corresponding ERP signatures have been labeled stop N1 (+/- 100-ms latency), stop N2 (200 ms), and stop P3 (160–250 ms), and argued to reflect more sensory-specific (N1) versus more generic (N2, P3) mechanisms. However, stop N1 and stop N2, as well as latencies of stop-P3, appear to be quite inconsistent across studies. The present work addressed the possible influence of stop-signal salience, expecting high salience to induce clear stop N1s but reduced s…
Deviance detection in sound frequency in simple and complex sounds in urethane-anesthetized rats
2019
Mismatch negativity (MMN), which is an electrophysiological response demonstrated in humans and animals, reflects memory-based deviance detection in a series of sounds. However, only a few studies on rodents have used control conditions that were sufficient in eliminating confounding factors that could also explain differential responses to deviant sounds. Furthermore, it is unclear if change detection occurs similarly for sinusoidal and complex sounds. In this study, we investigated frequency change detection in urethane-anesthetized rats by recording local-field potentials from the dura above the auditory cortex. We studied change detection in sinusoidal and complex sounds in a series of …