Search results for "elements"

Possible Editing of Alu Transcripts in Blood Cells of Sporadic Creutzfeldt–Jakob Disease (sCJD)

2011

Editing of RNA molecules gained major interest when coding mRNA was analyzed. A small, noncoding, Alu DNA element transcript that may act as regulatory RNA in cells was examined in this study. Alu DNA element transcription was determined in buffy coat from healthy humans and human sporadic Creutzfeldt-Jakob disease (sCJD) cases. In addition, non-sCJD controls, mostly dementia cases and Alzheimer's disease (AD) cases, were included. The Alu cDNA sequences were aligned to genomic Alu DNA elements by database search. A comparison of best aligned Alu DNA sequences with our RNA/cDNA clones revealed editing by deamination by ADAR (adenosine deaminase acting on RNA) and APOBEC (apolipoprotein B ed…

Extensive nuclear gyration and pervasive non-genic transcription during primordial germ cell development in zebrafish.

2020

ABSTRACT Primordial germ cells (PGCs) are the precursors of germ cells, which migrate to the genital ridge during early development. Relatively little is known about PGCs after their migration. We studied this post-migratory stage using microscopy and sequencing techniques, and found that many PGC-specific genes, including genes known to induce PGC fate in the mouse, are only activated several days after migration. At this same time point, PGC nuclei become extremely gyrated, displaying general broad opening of chromatin and high levels of intergenic transcription. This is accompanied by changes in nuage morphology, expression of large loci (PGC-expressed non-coding RNA loci, PERLs) that ar…

INDUSTRY 4.0 AS SMART ENABLER FOR INNOVATIVE BUSINESS MODELS

2017

Master's thesis Business Administration BE501 - University of Agder 2017 Industry 4.0 is the upcoming 4th revolution within industrial setups across the world, mainly in manufacturing hubs. Industrial internet of Things (IIOT) will alter the dimensions of the way businesses used to be conducted and the way value was assessed and retrieved. IIOT tends to have a critical impact on the business models (BM) within various industrial sectors, either manufacturing or services. This study tries to observe IIOT related effects on the business models in regards to manufacturing industry from a Tech-based consultancy point of view. This study employs exploratory multiple case study approach to the to…

Meso-modeling of heterogeneous structures via interphase model

2010

Comparison between the MHFEM formulation and a 2nd spatial order FV formulation of the linear groundwater flow problem

2008

Mixed and Mixed Hybrid Finite Elements (MHFE) methods have been widely used in the last decade for simulation of groundwater flow problem, petroleum reservoir problems, potential flow problems, etc. The main advantage of these methods is that, unlike the classical Galerkin approach, they guarantee local and global mass balance, as well the flux continuity between inter-element sides. The simple shape of the control volume, where the mass conservation is satisfied, makes also easier to couple this technique with a Finite Volume technique in the time splitting approach for the solution of advection-dispersion problems. In the present paper a new second spatial approximation order Finite Volum…

Management Elements Proposal for Sutla Natura 2000 Site

2015

Abstract Following the accession of Croatia to the EU, a study was carried out on a Croatian Natura 2000 site which includes habitats used by the following fish species of conservation interest: Eudontomyzon vladykovi, Rhodeus sericeus amarus, Gobio uranoscopus, Romanogobio kesslerii, Barbus meridionalis, Zingel streber and Cottus gobio. Harmful effects on fish fauna were found due to: poorly-integrated water management, over-extraction of water for irrigation, fragmentation of riparian vegetation, low cooperation between environment institutions in Croatia and Slovenia, abuse of pesticides, uncontrolled waste water, sources of chemicals and heavy metals, leakage of nitrogen, habitats fragm…

Inductively coupled plasma optical emission spectroscopy determination of trace element composition of argan oil.

2011

A methodology based on inductively coupled plasma optical emission spectroscopy (ICP-OES) after microwave assisted acid digestion has been developed to determine the trace element content of Moroccan argan oil. Limit of detection values equal or lower than few mg/kg were obtained for all elements under study. To assure the accuracy of the whole procedure, recovery studies were carried out on argan oil samples spiked at different concentration levels from 10 to 200 µg/L. Quantitative average recovery values were obtained for all elements evaluated, demonstrating the suitability of this methodology for the determination of trace elements in argan oil samples. Aluminum, calcium, chromium, iro…

Absence of the endo-beta-1,4-glucanases Cel1 and Cel2 reduces susceptibility to Botrytis cinerea in tomato.

2007

Cel1 and Cel2 are members of the tomato (Solanum lycopersicum Mill) endo-beta-1,4-glucanase (EGase) family that may play a role in fruit ripening and organ abscission. This work demonstrates that Cel1 protein is present in other vegetative tissues and accumulates during leaf development. We recently reported the downregulation of both the Cel1 mRNA and protein upon fungal infection, suggesting the involvement of EGases in plant-pathogen interactions. This hypothesis was confirmed by assessing the resistance to Botrytis cinerea infection of transgenic plants expressing both genes in an antisense orientation (Anti-Cel1, Anti-Cel2 and Anti-Cel1-Cel2). The Anti-Cel1-Cel2 plants showed enhanced …

Spin-multipole nuclear matrix elements in the pn quasiparticle random-phase approximation: Implications for β and ββ half-lives

2017

Half-lives for 148 potentially measurable 2nd-, 3rd-, 4th-, 5th-, 6th-, and 7th-forbidden unique beta transitions are predicted. To achieve this, the ratio of the nuclear matrix elements (NMEs), calculated by the proton-neutron quasiparticle random-phase approximation (pnQRPA), MpnQRPA, and a two-quasiparticle (two-qp) model, Mqp, is studied and compared with earlier calculations for the allowed Gamow-Teller (GT) 1+ and first-forbidden spin-dipole (SD) 2− transitions. The present calculations are done using realistic single-particle model spaces and G-matrix based microscopic two-body interactions. In terms of the ratio k = MpnQRPA/Mqp the studied decays fall into two groups: for GROUP 1, w…

"Se on semmosta arkipäivää" : liikunta esiopetusryhmän kuvaamana ja toteuttamana

2012

Tiivistelmä. Saastamoinen, Anna & Sirniö, Sanna. 2012. ”SE ON SEMMOSTA ARKIPÄIVÄÄ”. Liikunta esiopetusryhmän kuvaamana ja toteuttamana. Varhaiskasvatustieteen pro gradu -tutkielma. Kasvatustieteiden laitos. Jyväskylän yliopisto. 120 sivua + liitteet. Tämän tutkimuksen lähtökohtana oli liikunnan vankka asema suomalaisessa yhteiskunnassa, ja siihen latautuvat positiiviset merkitykset. Yhteiskunnassamme puhutaan nykyään paljon lasten liikunnan vähentymisestä, liikuntamahdollisuuksien muuttumisesta sekä ohjatun liikunnan lisääntymisestä. Liikunta on käsitteenä monimuotoinen, ja sillä on sekä itseisarvoisia että välineellisiä tehtäviä. Esiopetuksessa toteutettavalla liikuntakasvatuksella on merk…