Search results for "english"
showing 10 items of 846 documents
Role of heat shock protein HSP90 and HSP70 in macrophagic differentiation
2010
Heat shock proteins (HSPs) are molecular chaperones whose expression is increased after many different stresses. They have a protective function helping the cell to cope with lethal conditions. These proteins play an essential role as molecular chaperones by assisting the correct folding of nascent and stress-accumulated misfolded proteins and by preventing their aggregation. My team is interested in understanding the roles of HSPs in two physiological related processes: apoptosis and cell differentiation. The aim of my work is to study the functions of HSP90 and HSP70 in macrophagic differentiation. I first studied the role of HSP90 in macrophagic differentiation. We previously reported th…
Impact du système endocannabinoïdien sur la physiologie de l'obésité : effets de l'antagonisme des récepteurs CB1 sur le métabolisme glucido-lipidiqu…
2010
The endocannabinoïd system (ECS) is involved in many biological functions such as regulation of energy metabolism. Recently, several studies have shown an association between obesity and ECS overactivity. In addition, specific CB1R antagonists such as Rimonabant (SR141716) improved metabolic parameters in obese patients essentially through inactivation of central CB1R. However, peripheral CB1R inactivation could also contribute to the improvement of these parameters and it is this notion that we have studied. To this purpose, we tested the effects of SR141716 on obese mice in order to establish relationships between the ECS activity and lipid metabolism by looking more specifically to its r…
Monetary images of celtic people : primitive figures or expressions of a changing society ? : the case of Arveni, Bituriges, Carnutes, Aedui, Lingone…
2011
The study is based on approximately 600 monetary images attributed to Arverni, Bituriges, Carnutes, Aedui, Lingones, Sequani, Parisii, Meldi and Senones. Monetary images form the largest iconographic set provided by the Celts but paradoxically, they are not considered at their fair value in the current research. Indeed, their study is a relatively recent discipline because the Celts left no text allowing their understanding. The different themes of the images relate to religion, society and aristocracy of Iron Age. The multidisciplinary approach (archaeological, literary and artistic) of this work recreates links between monetary images and the celtic society and compleets many areas of stu…
Animaux domestiques et faunes sauvages en territoire Arverne (Vème avant JC - 1er siècle après JC)
2010
This thesis is based upon the study of 160 000 animal bones issued from 23 late iron-age sites excavated in the Auvergne region of central France. The assemblages represent different types of archaeological contexts (farms, aristocratic settlements, agglomerations, oppida, religious/ritual zones and funeral areas) which enable us to study their role in the domestic, craft and sacrificial spheres. The aim of this thesis is to show the implications of animal use within the Gallic society.This thorough study also replaces the data into the chronological context of Gaul between the LaTèneien and Augustian periods, and the geographical territory of the Clermont-Ferrand Basin in the Limagne plain…
The ceramic of Middle Neolithic II between the valleys of the Yonne and the Saône, between 4300 and 3400 BC
2010
The territory between the valleys of the Yonne and the Saône has always been a zone of cultural meeting in particular during the middle Neolithic II, between 4300 and 3400 BC. Since the 1970's, the culture of the Néolithique moyen bourguignon (N.M.B.) has been recognized in this region and its main characteristics were defined during a round table discussion organized in Beffia in 1984 (Pétrequin and Gallay 1984). From criteria based essentially on the ceramic typology, the N.M.B. is then mainly confined within the regions of Burgundy and Franche-Comté.Since 1984, the zone of there culture has been expended in particular to the South and Southwest. Multiple deposits have been discovered sin…
For a semiotic approach of the strategic field of communication
2010
The purpose of this work is to highlight a critical view on communication field and mass consumption, at the crossroad of a double path bridging academic research and professional practice of the author. The semiotics approach, enriched with the light of disciplines like communication sciences, strategy, interaction, anthropology, enables to draft a theory of strategy in the communication field. By considering the latter as a strategic space of actualization of stakes for the actants, ruled by confrontation and rivalry, we bring ourselves the opportunity to consider this field and the phenomenon that are structuring it at its right level. This multiple approach unified by the conceptual and…
"Save the Night" : light footprint, urbanism and territorial governance
2010
Our society maintains a complex relation with night, space-time often outside the diurnal cadences which facilitates the reflection, the imagination, the creation, the listening and the link with the other one, while revealing the segregation, the fear, and thus the restriction. By this research, we put compared to the urban lighting – real light project carrier of a strong symbolism – the socio-cultural, ecological and sanitary costs engendered by the artificial light. The urban lighting generates a geographical interlacing of bright imprints of differentiated scales, which we approach by various modellings, without forbidding us the sensitive analysis. We clarify, at various scales, the g…
The diversion of institution
2010
The diversion of an institution is a notion which was established by the jurisprudence of the « French Court of Cassation », in the early 1990s, about adoption and the phenomena of surrogate mothers.From a chronological point of view, the diversion of institution first broke away from the studies of the doctrine dedicated to the abuse of rights , and was first used by the jurisprudence in labour law, before being dedicated to family rights. Because it deals with diversion of the finality of a legal system institution, it is often confused with the abuse of rights, the abuse of power, and fraud of the law or similar. Nevertheless, common points between the diversion of institution and other …
La violence scolaire féminine : un regard d'adolescentes
2012
No abstract
“Linearity, an English Trait?”
2009
This article looks at how the « English line” became one of the defining features of Englishness from the 1920s to the 1950s. It is based on texts by Michael Ayrton, Robin Ironside, John Piper and Nikolaus Pevsner that were published during or just after the Second World War, and that contributed to a contemporary critical reassessment of English art.