Search results for "enhancement"
showing 10 items of 566 documents
"Figure 11" of "Cold-nuclear-matter effcts on heavy-quark production in d+Au collisions at sqrt(s_NN)=200 GeV"
2023
Heavy flavor electron $R_{dA}$ 60-88% $d$+Au collisions. The nuclear modification factor, $R_{dA}$, for electrons from open heavy flavor decays, for the (a) most central and (b) most peripheral centrality bins.
"Figure 8" of "Cold-nuclear-matter effcts on heavy-quark production in d+Au collisions at sqrt(s_NN)=200 GeV"
2023
Heavy flavor electron RdA 0-20% $d$+Au collisions. The nuclear modification factor, $R_{dA}$, for electrons from open heavy flavor decays, for the (a) most central and (b) most peripheral centrality bins.
"Figure 9" of "Cold-nuclear-matter effcts on heavy-quark production in d+Au collisions at sqrt(s_NN)=200 GeV"
2023
Heavy flavor electron $R_{dA}$ 20-40% $d$+Au collisions. The nuclear modification factor, $R_{dA}$, for electrons from open heavy flavor decays, for the (a) most central and (b) most peripheral centrality bins.
"Figure 7" of "Cold-nuclear-matter effcts on heavy-quark production in d+Au collisions at sqrt(s_NN)=200 GeV"
2023
Heavy flavor electron $R_{dA}$ 0-100% d+Au collisions. The nuclear modification factors $R_{dA}$ and $R_{AA}$ for minimum bias $d$+Au and Au+Au collisions, for the $\pi^{0}$ and $e^{\pm}_{HF}$. The two boxes on the right side of the plot represent the global uncertainties in the $d$+Au (left) and Au+Au (right) values of $N_{coll}$ . An additional common global scaling uncertainty of 9.7% on $R_{dA}$ and $R_{AA}$ from the $p+p$ reference data is omitted for clarity.
"Figures 3-6" of "Cold-nuclear-matter effcts on heavy-quark production in d+Au collisions at sqrt(s_NN)=200 GeV"
2023
Heavy flavor electron yield, $d$+Au $\implies$ CHARGED X. Electrons from heavy flavor decays, separated by centrality. The lines represent a fit to the previous $p+p$ result [23], scaled by $N_{coll}$. The inset shows the ratio of photonic background electrons determined by the converter and cocktail methods for Minimum Bias $d$+Au collisions, with error bars (boxes) that represent the statistical uncertainty on the converter data (systematic uncertainty on the photonic-electron cocktail).
"Figure 10" of "Cold-nuclear-matter effcts on heavy-quark production in d+Au collisions at sqrt(s_NN)=200 GeV"
2023
Heavy flavor electron $R_{dA}$ 40-60% $d$+Au collisions. The nuclear modification factor, $R_{dA}$, for electrons from open heavy flavor decays, for the (a) most central and (b) most peripheral centrality bins.
"Figures 1-2" of "Cold-nuclear-matter effcts on heavy-quark production in d+Au collisions at sqrt(s_NN)=200 GeV"
2023
Heavy flavor electron yield, Run-8 $p$ + $p$, $d$+Au collisions. Electrons from heavy flavor decays, separated by centrality. The lines represent a fit to the previous $p+p$ result [23], scaled by $N_{coll}$. The inset shows the ratio of photonic background electrons determined by the converter and cocktail methods for Minimum Bias $d$+Au collisions, with error bars (boxes) that represent the statistical uncertainty on the converter data (systematic uncertainty on the photonic-electron cocktail).
Lipid Nanoparticles as Potential Gene Therapeutic Delivery Systems for Oral Administration.
2017
Background Gene therapy has experimented an increasing attention in the last decades, due to its enormous potential applications in the medical field. It can be defined as the use of genes or genetic material (DNA, RNA, oligonucleotides) to treat or prevent a disease state, generally a geneticbased one. Application Other applications, like treating viral, bacterial or parasite infections or development of vaccines are gaining also interest. Efficient gene therapy is mainly dependent on the ability of the highly labile genetic material to reach the therapeutic target. For this purpose, different delivery systems have been designed and extensively investigated. Nanoparticles offer a broad ran…
Bioethics and neuroethics
2019
Neuroethics officially appeared at the start of the 21st century due to the progress made by the neurosciences, as an applied ethics related to bioethics, but also as an independent discipline in its own right. As an applied ethics, it tackles issues bordering on bioethics. As independent neuroethics, it deals with established philosophical problems from a neuroscientific standpoint in the broader sense. It involves two central questions: the design of a framework in which to select, interpret and integrate data from neuroscience on morality and outlining the appropriate method or methods for this new branch of knowledge. In both cases, most neuroethicists curiously claim to take a naturali…
Engineering CRISPR guide RNA riboswitches for in vivo applications
2019
CRISPR-based genome editing provides a simple and scalable toolbox for a variety of therapeutic and biotechnology applications. Whilst the fundamental properties of CRISPR proved easily transferable from the native prokaryotic hosts to eukaryotic and multicellular organisms, the tight control of the CRISPR-editing activity remains a major challenge. Here we summarise recent developments of CRISPR and riboswitch technologies and recommend novel functionalised synthetic-gRNA (sgRNA) designs to achieve inducible and spatiotemporal regulation of CRISPR-based genetic editors in response to cellular or extracellular stimuli. We believe that future advances of these tools will have major implicati…