Search results for "enviroment"
showing 10 items of 21 documents
Danno all'ambiente e tutela della persona
2012
Il libro propone una riflessione sul danno ambientale, inquadrandola nella più ampia prospettiva della tutela della persona, alla quale la figura del danno ambientale sembra potersi ascrivere. Delineata la disciplina in tema di danno all'ambiente, quale emergente dal lungo iter normativo, dottrinale e giurisprudenziale, che ne ha segnato la sua evoluzione, emerge l'idea di un danno ambientale, che potrebbe definirsi esistenziale, in grado di suggerire riflessioni interessanti, tanto in tema di responsabilità ambientale, quanto riguardo all'area del danno alla persona. La parabola del danno ambientale, se continua forse oggi ad evocare pericolosi "mostriciattoli", è figlia della storia di un…
Advanced microscopy analysis of the micro-nanoscale architecture of human menisci
2019
AbstractThe complex inhomogeneous architecture of the human meniscal tissue at the micro and nano scale in the absence of artefacts introduced by sample treatments has not yet been fully revealed. The knowledge of the internal structure organization is essential to understand the mechanical functionality of the meniscus and its relationship with the tissue’s complex structure. In this work, we investigated human meniscal tissue structure using up-to-date non-invasive imaging techniques, based on multiphoton fluorescence and quantitative second harmonic generation microscopy complemented with Environmental Scanning Electron Microscopy measurements. Observations on 50 meniscal samples extract…
Long-Term Remission Achieved by Ponatinib and Donor Lymphocytes Infusion in a Ph+ Acute Lymphoblastic Leukemia Patient in Molecular Relapse After All…
2020
Currently, the prognosis of Ph+ acute lymphoblastic leukemia (Ph+ ALL) patients relapsing after an allogenic hematopoietic stem cell transplantation (allo-SCT) remains poor, with few therapeutic options available. Here we present the case of a 32 years old patient with dasatinib-resistant post-transplant molecular relapse of ALL, who received, as second-line therapy, the combination of ponatinib and donor lymphocyte infusion (DLI). The therapy was safe and the patient achieved a sustained minimal residual disease negative disease, still ongoing after 22 months, which was accompanied by several changes in the immune populations distribution within the bone marrow (i.e., the increase in the C…
γδ cells and tumor microenvironment: A helpful or a dangerous liason?
2017
Abstract γδ T cells are a subset of T lymphocytes that have been implicated in immunosurveillance against infections and tumors. γδ T cells are endowed with antitumor activities, and hence several γδ T cell-based small-scale clinical trials have been conducted either by in vivo activation by intravenous administration of aminobiphosphonates or by adoptive transfer of in vitro expanded γδ T cells. Although both these strategies have yielded promising results, there are a number of limitations associated with each of them which, if overcome may help to further improve efficacy. One of the most important limits is the possible polarization of tumor-infiltrating γδ T cells toward different γδ T…
Diseño e implementación de una aplicación en Processing para la representación visual de datos multidimensionales utilizando técnicas de Minería de D…
2015
La posibilidad de disponer de representaciones gráficas de los datos es de gran valor a la hora de extraer conocimiento útil. Sus principales ventajas son la visualización de información de una forma sencilla, rápida y directa. No obstante, muchos de los conjuntos de datos contienen numerosos registros, que pueden ser de naturaleza multivariante. En estos casos, la representación visual de datos se convierte en una tarea complicada y las técnicas clásicas que suelen utilizarse obtienen resultados poco intuitivos. Esta tesis se plantea como objetivo el diseño e implementación de una aplicación versátil capaz de representar visualmente gran cantidad de datos multidimensionales de forma eficaz…
El problema de la generación de residuos urbanos entre los contenidos de geografía de la enseñanza secundaria obligatoria
2002
Una de las características del problema de los Residuos Urbanos en nuestro país es la escasa conciencia ambiental de los ciudadanos. En este trabajo se exponen las grandes posibilidades que ofrece el currículo del Área de “Ciencias Sociales, Geografía e Historia” de la Enseñanza Secundaria Obligatoria (E.S.O.) para llevar a cabo acciones de Educación Ambiental, destacando así la capacidad de los profesores de Geografía para intentar mejorar la situación actual. Solid wastes generation problem into Secondary School Geography´s contents Citizenship’s low environmental conscience is a characteristic of Solid Wastes situation in Spain. In this paper, “Social Sciences, Geography and History” cur…
A survey on the microclimate in Palermo city using the public transport system
2006
This work presentes the results of an extensive survey on the microclimate in Palermo city using the public transport system
Targeting of multiple myeloma-related angiogenesis by miR-199a-5p mimics: in vitro and in vivo anti-tumor activity
2014
// Lavinia Raimondi 1 , Nicola Amodio 1 , Maria Teresa Di Martino 1 , Emanuela Altomare 1 , Marzia Leotta 1 , Daniele Caracciolo 1 , Annamaria Gulla 1 , Antonino Neri 2 , Simona Taverna 3 , Patrizia D’Aquila 4 , Riccardo Alessandro 3 , Antonio Giordano 5 , Pierosandro Tagliaferri 1 and Pierfrancesco Tassone 1,5 . 1 Department of Experimental and Clinical Medicine, Magna Graecia University and Medical Oncology Unit, T. Campanella Cancer Center, Salvatore Venuta University Campus, Catanzaro, Italy 2 Department of Medical Sciences University of Milan, Hematology1, IRCCS Policlinico Foundation, Milan, Italy 3 Department of Pathology and Forensic and Medical Biotechnology, Section of Biology and…
Challenges in Energy Systems for the Smart- Cities of the Future
2012
In the last years the European Union has actively promoted the renewable energies and the Combined Heat and Power (CHP) also for residential and tertiary buildings. The exploitation of renewable sources and cogeneration seems hampered by the regulatory wall that prohibit for residential, tertiary and commercial buildings the constitution of users clusters. In fact, the unification up to a threshold value of some tens of kVA, at least, can facilitate the installation of renewable energy power plants as solar PV modules or CHP systems (cogeneration) or CCHP systems (tri-generation), overcoming technical and economical barriers and combining several load profiles. The actual distribution syste…
The sterilization of eco-criticism: from sustainable development to green capitalism
2015
[eng] Development has been a dominant and highly visible trope of the global political and economic life of the world since the 1950s. As such it has been inevitably linked to some of the most important social processes of this era: colonialism, globalization, postcolonialism, global ecological crisis, the rise of environmentalism, and more. The consolidation of the contemporary consumer global society came, hand by hand, with the certainty that it sustained a way of life that as a collateral damage, included a global ecological crisis. From many quarters of the world new voices raised concerns about the costs of globalization and proposed alternatives and solutions: modern eco-criticism wa…