Search results for "episode"
showing 10 items of 194 documents
Rorschach Characteristics and Comparison of First-Episode Psychotic Patients in Finland and Spain
2004
Identifier avec précision les troubles schizophréniques a toujours été un problème complexe et controversé. Les caractéristiques psychologiques de la schizophrénie ont donné lieu à un volume considérable de travaux et de débats. Ces dernières années sont apparus un nombre croissant d'articles portant sur les différences et similitudes des manifestations de la psychose selon les cultures, partant de l'idée que les caractéristiques de personnalité nationales pourraient contribuer aux tableaux psychopathologiques. Le but premier de cette étude est de mieux comprendre les troubles psychotiques par l'investigation de la structure de personnalité et du fonctionnement de patients faisant un premi…
T215. CLINICAL PREDICTORS OF HOSPITALIZTIONS IN FIRST EPISODE PSYCHOTIC PATIENTS: A NATURALISTIC FOLLOW UP STUDY
2018
Abstract Background Some naturalistic longitudinal studies of first psychotic episodes of the last 50 years have suggested associations between psychopathology and the remission of symptoms and the clinical course of disease.1 A recent study in a large sample of patients with schizophrenia has obtained significant results using the number of hospitalizations as outcome variable.2 The main objective of this study is to know if clinical and sociodemographic variables predict the number of hospitalizations after the first psychotic episode Methods Naturalistic, longitudinal follow-up study in a sample of 212 patients of first-episode psychosis attending public mental health service in Area 5 o…
Institutional recovery: a 10-year follow-up of persons after their first psychosis diagnosis. A critical reflexive approach
2018
Background: Despite repeated attempts, it has not been possible to reach a consensus on the definition of recovery. In this paper, we use the term “institutional recovery” and focus on the persons’ ...
Abstract # 3128 Metabolic-inflammatory status as predictor of clinical outcome at 1-year follow-up in patients with first episode psychosis
2019
Metabolic abnormalities and peripheral inflammation have been increasingly reported in patients at their first episode of psychosis (FEP) and associated with increased mortality. However, the impact of an abnormal metabolic-inflammatory status on the psychiatric outcome of FEP is understudied. This study aimed 1) to combine metabolic and inflammatory variables in factors accounting for an overall metabolic-inflammatory status in FEP patients; 2) to explore the association between these factors and clinical outcome at 1 year. We recruited 43 FEP patients and 50 healthy controls (HC). At baseline (T1) we measured high sensitivity C-reactive protein (hsCRP) as inflammatory biomarker, and body …
PATIENTS WITH THEIR FIRST EPISODE OF PSYCHOSIS (FEP) WHO USE CANNABIS HAVE NORMAL PREMORBID IQ
2012
Cannabis use is highly prevalent among people with schizophrenia and, coupled with impaired cognition, is thought to heighten the risk of illness onset. Paradoxically, several studies report lifetime cannabis use as a predictor of a better cognitive performance in psychotic patients. This case/control study was conducted in order to observe in a First Episode group the association between cannabis use lifetime and two measures of general cognition: current and pre-morbid IQ. The data are derived from the GAP study, a case-control study of first-episode psychosis (FEP) - South London and Maudsley Mental Health NHS Foundation Trust. 279 consenting subjects: 119 FEP patients (age 29.6±8.5; 70%…
Evolution of Cambrian and Early Ordovician arcs in the Kyrgyz North Tianshan: Insights from U-Pb zircon ages and geochemical data
2019
Abstract Geochronological, geochemical, and structural studies of magmatic and metamorphic complexes within the Kyrgyz North Tianshan (NTS) revealed an extensive area of early Palaeozoic magmatism with an age range of 540–475 Ma. During the first episode at 540–510 Ma, magmatism likely occurred in an intraplate setting within the NTS microcontinent and in an oceanic arc setting within the Kyrgyz-Terskey zone in the south. During the second episode at 500–475 Ma, the entire NTS represented an arc system. These two phases of magmatism were separated by an episode of accretionary tectonics of uncertain nature, which led to obduction of ophiolites from the Kyrgyz-Terskey zone onto the microcont…
Factors Associated with Mortality in Patients Experiencing First Episodes of Acquired Thrombotic Thrombocytopenic Purpura (aTTP). Results of the Span…
2019
Introduction: Acquired thrombotic thrombocytopenic purpura (aTTP) is a rare, but life-threatening, hematological disorder characterized by severe thrombocytopenia, hemolytic microangiopathic anemia, and frequent organ damage. The underlying pathophysiology of aTTP is a functional deficiency of plasma ADAMTS13 activity caused by antibodies directed against the ADAMTS13 protease. Despite plasma exchange (PEX) and immunosuppression with corticosteroids, and, more recently, rituximab, which achieve remission in most patients with aTTP, 10-20% of patients are refractory to treatment and die as a result of disease progression. Most of such deaths occur during first episodes of aTTP, as subsequent…
Atherogenic Ratios in Patients with Recurrent Acute Coronary Syndrome and Receiving Statin Therapy: Clinical Usefullness as Cardiovascular Predictors
2015
Patients who have already suffered a vascular event require more and better control of cardiovascular risk factors. Different atherogenic indexes such as TC/HDLc, LDLc/HDLc, apoB/apoA-I, LDLc/apoB and non-HDLc/HDLc have been used to follow-up the patients because of their predictive capacity of the lipid profile. The aim of this study was to evaluate atherogenic ratios as a marker of the lipid residual risk in high-risk patients receiving statin therapy and to know the changes produced by previous lipid-lowering drugs treatment for a previous coronary event. The study including patients admitted to coronary care units of six Spanish tertiary hospitals for Acute Coronary Syndrome (ACS). A to…
Education and long-term outcomes in first episode psychosis: 10-year follow-up study of the PAFIP cohort
2021
[Background] Lower levels of education have been associated with the development of psychosis. Investigating educational achievement in the first episode of psychosis (FEP) patients may shed light on the origins of the alterations and on the variability of outcomes in psychotic disorders.
Peripheral circulating cells with paroxysmal nocturnal haemoglobinuria phenotype after a first episode of cerebral sinus vein thrombosis: Results fro…
2019
Paroxysmal nocturnal haemoglobinuria (PNH) is a rare, potentially fatal disorder of haematopoietic stem cells caused by mutations in an X-linked gene called phosphatidylinositol glycan class A, characterised by intravascular haemolysis, bone marrow failure and thrombotic events. The disease can occur at any age, although preferentially it affects young adults; its estimated prevalence is about 1/500,000 [1]. Clinical symptoms are variable and can include haemolytic anaemia, moderate to severe impairment of haematopoiesis and, in approximately 40% of patients, thrombosis of the vessels of the abdomen, brain and skin [2]. Rare, atypical site thrombosis of the splanchnic veins or cerebral sinu…