Search results for "erot"
showing 10 items of 1485 documents
Palmitoylation of Endothelin Receptor A
1996
Post-translational modifications such as phosphorylation and palmitoylation play important roles for the function and regulation of receptors coupled to heterotrimeric guanyl nucleotide-binding proteins. Here we demonstrate that the human endothelin receptor A (ETA) incorporates [3H]palmitate. Mutation of a cluster of five cysteine residues present in the cytoplasmic tail of ETA into serine or alanine residues completely prevented palmitoylation of the receptor. The ligand binding affinity of the non-palmitoylated ETA mutants was essentially unchanged as compared to the palmitoylated wild type ETA suggesting that the replacement of the cysteine residues did not alter the overall structure o…
Study abroad and career identity : three narratives of English language students' journeys to English-speaking countries
2010
Kulttuurienväliset opiskelijavaihto-ohjelmat ovat kasvattaneet merkittävästi suosiotaan kuluneiden vuosikymmenten aikana. Kuitenkin vasta viime vuosina on herätty tutkimaan millaisia kokonaisvaltaisia vaikutuksia kulttuurirajojen ylittämisellä sekä vieraaseen kieli- ja kulttuuriympäristöön sopeutumisella on vaihto-opiskelijoiden identiteetille. Tämän tutkimuksen tarkoituksena on tarkastella seuraavaa kysymystä: millaisia vaikutuksia kansainvälisellä opiskelijavaihdolla on opiskelijan ammatilliselle identiteetille. Tutkielman aineisto on kerätty temaattisella ryhmähaastattelulla. Siinä kolme opiskelijaa kertoo opiskelijavaihtonsa aikaisista kieli- ja kulttuurikokemuksista sekä pohtii identit…
Assaying waterborne psychoactive drugs by the response to naturalistic predator cues in the stickleback (Gasterosteus aculeatus)
2020
Abstract Ecotoxicological effects of psychiatric drugs and drug metabolites released by the human population are of increasing environmental concern. In this study we evaluate behavioral responses to visual predator cues in wild caught three-spined stickleback (Gasterosteus aculeatus) after exposure to water-born citalopram, a widely prescribed selective serotonin reuptake inhibitor with antidepressant and anxiolytic effects. Fish were exposed to ecological relevant concentrations of citalopram (0.15 or 1.5 μg L−1) for 10 or 20 days. After drug exposure, individual fish were moved to a test arena where they were exposed to two naturalistic visual predator cues; a shadow from beneath, which …
Respirometry for the Characterization of Heterotrophic Biomass Activity: Application to a MBR Pilot Plant Operated with Two Different Start-Up Strate…
2016
A membrane bioreactor (MBR) pilot plant was operated in two subsequent experimental periods (namely, Periods I and II) with different start-up and sludge withdrawal strategies to study its peculiar biokinetic behavior by using respirometric techniques. Two extreme operational conditions were chosen to investigate the different biomass activity under dynamic or pseudostationary conditions during and after the start-up phases. Particularly, the MBR pilot plant was operated with the same volumetric loading rate (VLR) and permeate flux but differently managed during the start-up phase. In Period I, the MBR pilot plant was started up without sludge inoculum and operated without sludge withdrawal…
Does Culture Matter? : Measuring Cross-Country Perceptions of CSR Communication Campaigns about COVID-19
2022
The COVID-19 pandemic has brought several challenges to businesses and societies. In response, many corporations have supported local communities and authorities in the management of the pandemic. Although these initiatives, which can be considered forms of corporate social responsibility (CSR), were highly coupled with explicit CSR communication campaigns, little is known about whether these campaigns were effective. Previous research indicates that culture can shape people’s perceptions of CSR initiatives and communications, suggesting that businesses pay attention to careful consideration of cultural norms for effective CSR communication. However, the COVID-19 pandemic as a new CSR setti…
Axons take a dive
2014
In the walls of the lateral ventricles of the adult mammalian brain, neural stem cells (NSCs) and ependymal (E1) cells share the apical surface of the ventricular-subventricular zone (V-SVZ). In a recent article, we show that supraependymal serotonergic (5HT) axons originating from the raphe nuclei in mice form an extensive plexus on the walls of the lateral ventricles where they contact E1 cells and NSCs. Here we further characterize the contacts between 5HT supraependymal axons and E1 cells in mice, and show that suprependymal axons tightly associated to E1 cells are also present in the walls of the human lateral ventricles. These observations raise interesting questions about the functio…
ROLE OF SEROTONIN1A/2A/2C RECEPTORS IN THE MODULATION OF NORMAL AND PATHOLOGICAL HIPPOCAMPAL EXCITABILITY
2015
Behavioral Health Theories, Equity, and Disparities in Global Health : A Basic Process Model
2020
Lack of participation in health-promoting behaviors and participation in behaviors that contribute to health risks have been linked to health disparities observed among individuals from disadvantaged backgrounds. This chapter presents a basic process model to summarize the effects of socio-structural variables linked to health disparities – socioeconomic status, education, health literacy, ethnicity, and religiosity – on individuals’ beliefs and cognitions that determine behavior. Socio-structural characteristics were proposed to have a pervasive effect on individuals’ beliefs and other constructs from social cognition theories which impact their decisions to participate in prospective heal…
'In search of assessment feedback' : student view on the Finnish and British higher education
2007
Cómo domé un caracol en tus senos: sobre la delgada línea entre lo poético y lo irónico
2020
Matei Visniec (Rădăuţi, Rumanía, 1956) tiene sus raíces en Rumanía y sus alas en Francia, como él mismo ha afirmado. Censurado en su juventud por el régimen comunista, se autoexilió en Francia en 1987, lo que supuso un revulsivo en su trayectoria creativa. Además, aunque continuó escribiendo poesía y novela en rumano, adoptó progresivamente el francés para sus creaciones dramáticas. El universo dramático de Matei Visniec es poliédrico: construido sobre el rechazo de la literatura oficialista del régimen dictatorial que padeció, ha acogido una pluralidad de lenguajes creativos y combina la denuncia de las lacras de nuestros tiempos con la exploración poética de temas universales como el amor…