Search results for "erythrocytosis"

showing 5 items of 5 documents

Polyglobulie rare par mutation du gène EGLN1 : à propos d’un cas et revue de la littérature

2020

Resume Introduction Le diagnostic etiologique d’une polyglobulie est souvent simple, l’origine etant le plus souvent acquise. Parfois il faut rechercher des formes rares, hereditaires, l’algorithme decisionnel reposant sur le dosage de l’erythropoietine serique et sur la mesure de la pression en oxygene saturant l’hemoglobine a 50 % (P50). Ces pathologies sont en rapport avec des anomalies du recepteur a l’erythropoietine, des hemoglobines hyperaffines ou a des dysfonctionnements de la voie de regulation du facteur HIF (Hypoxia-Inducible Factor) implique dans la sensibilite renale a l’hypoxie. Observation Nous rapportons le cas d’un patient de 56 ans qui presente une polyglobulie inexplique…

0301 basic medicineGynecology03 medical and health sciencesmedicine.medical_specialty030104 developmental biology0302 clinical medicinebusiness.industryGastroenterologyInternal MedicineMedicineHereditary Erythrocytosisbusiness030215 immunologyLa Revue de Médecine Interne
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High HFE mutation incidence in idiopathic erythrocytosis.

2018

0301 basic medicinemedicine.medical_specialtybusiness.industryIncidence (epidemiology)IncidenceHematologyPolycythemiaGastroenterology03 medical and health sciences030104 developmental biology0302 clinical medicine030220 oncology & carcinogenesisInternal medicineMutation (genetic algorithm)MutationmedicineHumansIdiopathic erythrocytosisbusinessHemochromatosis ProteinBritish journal of haematology
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Low incidence of <i>EPOR</i> mutations in idiopathic erythrocytosis

2020

Erythropoietinbusiness.industryIncidence (epidemiology)Mutation (genetic algorithm)medicineIdiopathic erythrocytosisHematologybusinessBioinformaticsReceptormedicine.drugErythropoietin receptorHaematologica
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COMPARISON OF CLINICAL AND LABORATORY DATA, INCLUDING JAK-2 46/1 HAPLOTYPE, BETWEEN PATIENTS WITH IDIOPATHIC ERYTHROCYTOSIS AND POLYCYTHEMIA VERA.

2017

Polycythemia vera Haplotype analysis erythrocytosis
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Diagnosis of exon 12‐positive polycythemia vera rescued by NGS

2020

Abstract A JAK2V617F‐negative polycythemia associated with low serum epo needs to be tested for an exon 12 JAK2 mutation. When negative, due to potential serious complications in PV, a next generation sequencing is necessary to rule out false negative results.

lcsh:MedicineCase ReportCase Reports030204 cardiovascular system & hematologyDNA sequencing03 medical and health sciencesExon0302 clinical medicinePolycythemia veraExon 12polycythemia verahemic and lymphatic diseasesmedicineerythrocytosisnext generation sequencinglcsh:R5-920business.industryJak2 mutationlcsh:RGeneral Medicinemedicine.diseaseVirologyJAK2030220 oncology & carcinogenesisbusinesslcsh:Medicine (General)Clinical Case Reports
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