Search results for "esca"
showing 10 items of 966 documents
MicroRNAs play a central role in molecular dysfunctions linking inflammation with cancer.
2013
It is now largely admitted that a pro-inflammatory environment may curtail anti-tumor immunity and favor cancer initiation and progression. The discovery that small non-coding regulatory RNAs, namely microRNAs (miRNAs), regulate all aspects of cell proliferation, differentiation, and function has shed a new light on regulatory mechanisms linking inflammation and cancer. Thus, miRNAs such as miR-21, miR-125b, miR-155, miR-196, and miR-210 that are critical for the immune response or hypoxia are often overexpressed in cancers and leukemias. Given the high number of their target transcripts, their deregulation may have a number of deleterious consequences, depending on the cellular context. In…
Grouping facilitates avoidance of parasites by fish
2013
Background. Parasite distribution is often highly heterogeneous, and intensity of infection depends, among other things, on how well hosts can avoid areas with a high concentration of parasites. We studied the role of fish behaviour in avoiding microhabitats with a high infection risk using Oncorhynchus mykiss and cercariae of Diplostomum pseudospathaceum as a model. Spatial distribution of parasites in experimental tanks was highly heterogeneous. We hypothesized that fish in groups are better at recognizing a parasitized area and avoiding it than solitary fish. Methods. Number of fish, either solitary or in groups of 5, was recorded in different compartments of a shuttle tank where fish co…
Manipulation of fish host by eye flukes in relation to cataract formation and parasite infectivity
2005
Trophically transmitted parasites may predispose infected hosts to predation by altering host behaviour, which can be either an adaptation of the parasites to enhance transmission to the next hosts in the life cycle or a nonadaptive side-effect of infection. In an experimental study, we investigated host manipulation by Diplostomum spathaceum (Trematoda), an eye fluke of fish, to evaluate its adaptive value as a parasite strategy to increase transmission efficiency to bird hosts. The parasite induces cataract formation in the lenses of fish eyes, and predisposes fish to predation by reducing their escape response. We examined the effect of developmental stage and the number of parasites on …
TLR4 expression in ex-Lichenoid lesions—oral squamous cell carcinomas and its surrounding epithelium: the role of tumor inflammatory microenvironment
2022
Toll-like receptors (TLRs) regulate innate and adaptive immune responses. Moreover, TLRs can induce a pro-survival and pro-proliferation response in tumor cells. This study aims to investigate the expression of TLR4 in the epithelium surrounding oral squamous cell carcinomas (OSCC) in relation to its inflammatory microenvironment. This study included 150 human samples: 30 normal oral control (NOC), 38 non-lichenoid epithelium surrounding OSCC (NLE-OSCC), 28 lichenoid epithelium surrounding OSCC (LE-OSCC), 30 OSCC ex-non oral lichenoid lesion (OSCC Ex-NOLL), and 24 OSCC ex-oral lichenoid lesion (OSCC Ex-OLL). TLR4 expression was investigated by immunohistochemistry and the percentage of posi…
“Alimental, querido Watson” – Escape room virtual para la asignatura de Alimentación y Dietética
2021
[EN] "Alimental, querido Watson" is a digital educational escape room created for the subject "Nutrition and Dietetics" of the degree in Medicine at the University of Valencia. The objective of this activity was to maintain the students participation and adherence in the subject in spite of being teached in an on-line asynchronous way during the 2020/2021 academic year. Furthemore, we also wanted to encourage their learning by solving the different enigmas, always related to the contents of the subject. The results from this activity show that, as expected, students had a greater involvement and satisfaction with the activity, as well as a higher academic performance. Therefore, our experie…
Impatto potenziale dei programmi sviluppabili dal Distretto in termini di innovazione, sviluppo e risparmio energetico sulle imprese della filiera
2014
Se da un lato l’energia ed il suo costo rappresentano da tempo una delle più serie limitazioni alla sostenibilità del settore della pesca, dall’altro lato affrontare questo tema in un’ottica di innovazione può costituire un interessante fattore di sviluppo e di innovazione del settore stesso. Non è del resto un caso che ai temi della sostenibilità siano ispirate le linee guida del nuovo programma europeo Horizon 2020, Work Programme 2014-2010; come è noto, tra le sette sfide principali del programma europeo, una è espressamente riservata alla ricerca marina e marittima (“Food Security, Sustainable Agriculture, Marine and maritime research and the bio-economy”). Nell’ambito dei programmi svi…
Zwischen Okzident und Orient. Rezension zu:SAID – ich, jesus von nazareth. Würzburg: Echter, 2018, 59 S.
2021
Der Gegenstand der Besprechung ist das kleine Buch des 2021 verstorbenen deutsch-iranischen Schriftstellers SAID. Es wird auf den Beitrag des Schriftstellers zum kulturellen Austausch zwischen Okzident und Orient hingewiesen. Hervorgehoben werden dabei die ästhetische und ethische Leistung des Autors sowie der Stellenwert des kleinen Werks im Schaffen SAIDs.
Pronunciare bene. Fonetica italiana e tedesca a confronto
2017
Come si fa ad acquisire una buona pronuncia? Questo libro – che si rivolge a italofoni che studiano o insegnano il tedesco e a germanofoni che studiano o insegnano l’italiano – mette a disposizione tutto il background teorico necessario per quanto riguarda la pronuncia di entrambe le lingue. La descrizione in parallelo dell’italiano e del tedesco fornisce le basi per un confronto tra i due differenti sistemi fonologici. Che cosa hanno in comune e in che cosa si differenziano? Quali errori ci si può aspettare dagli italofoni che si esprimono in tedesco e dai germanofoni che si esprimono in italiano? Grazie a quali accorgimenti si possono evitare gli errori riuscendo così a “pronunciare bene”…
Una traducció cancelleresca: el Libre de les costumes dels hòmens e dels oficis dels nobles sobre lo joc dels escachs de Jaume de Cèssulis
2007
Del tractat del dominicà llombard Jacobus de Cessulis, el Liber de moribus (ca. 1300), libre d’èxit extraordinari durant molts segles, recull d’exemples i sentències i regiment de prínceps bastit sobre la modelització dels escacs, coneixem molts textos llatins i múltiples traduccions europees, dels segles XIV i XV. De traduccions catalanes, en coneixem dues, la primera de les quals, que datem entre 1370 i 1385, serà l’objecte d’estudi de la present comunicació. La segona, més tardana (de finals del s. XV), i amb un grau d’intervenció major respecte l’original (amb alleugeriments estilístics i supressions), ens ajudarà a definir i contrastar la intenció i el mètode traductològic d’aquesta pr…
Gozos del milagrosisimo Christo del Rescate, venerado en el Convento de Santa Tecla.
El full orlat Grav. xil. enmarcat del Crist Text del goig a tres col. separades per filets