Search results for "etica."
showing 10 items of 13546 documents
Thiazole Analogues of the Marine Alkaloid Nortopsentin as Inhibitors of Bacterial Biofilm Formation
2020
Anti-virulence strategy is currently considered a promising approach to overcome the global threat of the antibiotic resistance. Among different bacterial virulence factors, the biofilm formation is recognized as one of the most relevant. Considering the high and growing percentage of multi-drug resistant infections that are biofilm-mediated, new therapeutic agents capable of counteracting the formation of biofilms are urgently required. In this scenario, a new series of 18 thiazole derivatives was efficiently synthesized and evaluated for its ability to inhibit biofilm formation against the Gram-positive bacterial reference strains Staphylococcus aureus ATCC 25923 and S. aureus ATCC 6538 a…
Protein tyrosine nitration and thiol oxidation by peroxynitrite-strategies to prevent these oxidative modifications.
2013
The reaction product of nitric oxide and superoxide, peroxynitrite, is a potent biological oxidant. The most important oxidative protein modifications described for peroxynitrite are cysteine-thiol oxidation and tyrosine nitration. We have previously demonstrated that intrinsic heme-thiolate (P450)-dependent enzymatic catalysis increases the nitration of tyrosine 430 in prostacyclin synthase and results in loss of activity which contributes to endothelial dysfunction. We here report the sensitive peroxynitrite-dependent nitration of an over-expressed and partially purified human prostacyclin synthase (3.3 μM) with an EC50 value of 5 μM. Microsomal thiols in these preparations effectively co…
Violência, evasão e exclusão na educação superior
2019
The present text focuses on a relationship between higher education, institutional and symbolic violence and exclusion, practicing as a challenge based on reflections on the existence of evasion in Brazilian university. Ignoring the educational institution as a direct responsible for these things, this text considers that a logic in University organization and operation helps to enlarge inequalities that provide the mechanisms of evasion; at the same time, it presents itself as a space of reference and a struggle against social inequalities and violence. On a provisional basis, the text stands out that: depending on the execution of educational procedures and practices undertaken by the ins…
Carbon Nitride-Based Catalysts for High Pressure CO2 Photoreduction
2022
In the current research, the productivity of CO2 photoreduction has been boosted by performing the reaction in an innovative photocatalytic reactor, which allows for operation up to 20 bar. A set of photocatalysts were used, including three types of pristine TiO2, i.e., one commercially prepared (Evonik P25), one home-prepared by flame spray pyrolysis (FSP), and one obtained by the hydrolysis of TiCl4 (TiO2exCl), a bare thermo-exfoliated carbon nitride (C3N4-TE), and binary materials composed of TiO2 and C3N4-TE. The photoreduction was carried out in water at pH 14 and in the presence of Na2SO3 as a hole scavenger. Hydrogen and very small amounts of CO were detected in the head space of the…
Unlocking mixed oxides with unprecedented stoichiometries from heterometallic metalorganic frameworks for the catalytic hydrogenation of CO 2
2021
[EN] Their complex surface chemistry and high oxygen lattice mobilities place mixed-metal oxides among the most important families of materials. Modulation of stoichiometry in mixed-metal oxides has been shown to be a very powerful tool for tuning optical and catalytic properties. However, accessing different stoichiometries is not always synthetically possible. Here, we show that the thermal decomposition of the recently reported metal-organic framework MUV-101(Fe, Ti) results in the formation of carbon-supported titanomaghemite nanoparticles with an unprecedented Fe/Ti ratio close to 2, not achievable by soft-chemistry routes. The resulting titanomaghemite phase displays outstanding catal…
Homo signator: "L'indistruttibilità dell'uomo primitivo". Un'archeologia della cultura visuale
Osservazioni in margine alla polemica Orsi-Bouhours
1998
Il presente lavoro si propone di riassestare la cronologia della polemica Orsi-Bouhours riponendo al suo giusto posto una negletta traduzione degli Entretiens d'Ariste et d'Eugène ad opera del gesuita messinese D. Jannò. Analizzando le peculiarità di tale versione, se ne evidenzia l'importanza per la diffusione delle idee del "je ne sais quoi" e del "dilicato"; si aggiungono inoltre delle postille sulla ricezione di questi concetti in Italia.
Applying the integrated trans-contextual model to mathematics activities in the classroom and homework behavior and attainment
2016
The aim of the present study was to test hypotheses of the trans-contextual model. We predicted relations between perceived autonomy support, autonomous motivation toward mathematics learning activities in an educational context, autonomous motivation toward mathematics homework in an out-of-school context, social-cognitive variables and intentions for future engagement in mathematics homework, and mathematics homework outcomes. Secondary school students completed measures of perceived autonomy support from teachers and autonomous motivation for in-class mathematics activities; measures of autonomous motivation, social-cognitive variables, and intentions for out-of-school mathematics homewo…
Deep transcriptome profile of early host responses to Huanglongbing in citrus fruit and leaf tissues.
2010
An Overview on the Use of miRNAs as Possible Forensic Biomarkers for the Diagnosis of Traumatic Brain Injury
2023
Determining the cause of death is one of the main goals of forensic pathology. However, conditions can occur in which common approaches—external inspection, autopsy, histology, etc.—might not be conclusive. With the advancement of molecular biology, several investigative techniques have been developed over the years, and the application as approaches complementary to routine procedures has proved useful in these cases. In this context, microRNA (miRNA) profiling has attracted increasing interest due to these molecules’ ability to regulate physiological and pathological processes. The evidence of differential miRNA expression in both animal models and human samples of traumatic brain injury …