Search results for "etics"

showing 10 items of 18578 documents

Brown trout (Salmo trutta L.) high genetic diversity around the Tyrrhenian Sea as revealed by nuclear and mitochondrial markers

2018

The brown trout (Salmo trutta L.) is widely distributed all around Europe but its natural diversity is threatened by massive stocking with Atlantic domestic strains. Describing the remaining natural genetic diversity and the proportion of domestic hatchery strains in rivers is a prerequisite for smart conservation. The high genetic diversity of brown trout populations around the Tyrrhenian Sea is well known. Use of twelve microsatellites has allowed description of the natural genetic structure of populations and detection of the consequences of stocking. Mitochondrial DNA control region sequences and the LDH-C1* gene enabled placement of each population into one of the six mitochondrial and…

0106 biological sciencesLineage (genetic)PopulationSettore BIO/05 - ZoologiaIntrogressionZoologyConservationAquatic ScienceBiology010603 evolutionary biology01 natural sciencesBrown trout14. Life underwaterConservation LDH-C1 Microsatellites mtDNA control regionTyrrhenian brown troutSalmoeducationMicrosatellitesmtDNA control regionGenetic diversityeducation.field_of_study[SDV.GEN.GPO]Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE]mtDNA010604 marine biology & hydrobiologyMicrosatellite[SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry Molecular Biology/Molecular biologycontrol regionbiology.organism_classificationTyrrhenian brown troutGenetic structureLDH-C1*mtDNA control region
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Genomic Analysis and Lineage Identification of SARS-CoV-2 Strains in Migrants Accessing Europe Through the Libyan Route

2021

Many African countries, representing the origin of the majority of refugees, asylum-seekers, and other migrants, toward regions bordering on the Mediterranean area, are experiencing sustained local transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Sicily is one of the main entry gates of migrants crossing into Europe. We conducted a pilot study, based on the full-genome sequencing of SARS-CoV-2 strains isolated from migrants coming to Sicily by crossing the Mediterranean Sea, with the aim to investigate the viral genome polymorphism and to describe their genetic variations and the phylogenetic relationships. On June 21, a nongovernmental organization vessel rescu…

0106 biological sciencesLineage (genetic)virusesPilot ProjectsGenomicsLibyaasylum-seeker010603 evolutionary biology01 natural scienceslaw.invention03 medical and health sciencesMediterranean seaPhylogeneticslawMediterranean SeaHumansGenetic variabilitySicilyPhylogeny030304 developmental biologyTransients and Migrants0303 health sciencesPhylogenetic treeSARS-CoV-2lcsh:Public aspects of medicinefungiPublic Health Environmental and Occupational HealthCOVID-19virus diseaseslcsh:RA1-1270Genomicsmolecular surveillanceBrief Research Reportlanguage.human_languageEuropemigrantGeographyTransmission (mechanics)Evolutionary biologyNGSAfricalanguagePublic HealthSicilianFrontiers in Public Health
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Correlational selection on pro- and anti-inflammatory effectors.

2012

9 pages; International audience; Parasites impose a permanent threat for hosts. As a consequence, immune defenses are important for host fitness. However, the immune response can also produce self-damage and impair host fitness if not properly regulated. Effectors that up- and downregulate the immune response should, therefore, evolve in concert, and be under the action of correlational selection. To address this issue, we assessed the shape of the selection operating on pro- and anti-inflammatory effectors following an inflammatory challenge in laboratory mice. We found that selection acts on the combination of these two traits as individuals that produced large amount of pro-inflammatory …

0106 biological sciencesLipopolysaccharidesMale[ SDV.IMM.IA ] Life Sciences [q-bio]/Immunology/Adaptive immunology01 natural sciencesMiceImmunopathologyDarwinian medicine[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisimmunopathologyGenetics0303 health sciencesEffectorFlow CytometryInterleukin-10Interleukin 10[SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunologyIL-10CytokinesRegression AnalysisFemalemedicine.symptomGeneral Agricultural and Biological Sciences[ SDV.MP.PAR ] Life Sciences [q-bio]/Microbiology and Parasitology/Parasitologymedicine.drug_classInflammationBiology010603 evolutionary biologysurvivalAnti-inflammatory03 medical and health sciencesImmune systemImmunityGeneticsmedicineEscherichia coliAnimals[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/ParasitologySelection GeneticEcology Evolution Behavior and SystematicsSelection (genetic algorithm)030304 developmental biologyIL-6[ SDE.BE ] Environmental Sciences/Biodiversity and Ecologyevolutionary immunologyInterleukin-6inflammationImmunology[SDE.BE]Environmental Sciences/Biodiversity and Ecology[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/SymbiosisEvolution; international journal of organic evolution
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Anhydrobiosis in Yeasts: Changes in Mitochondrial Membranes Improve the Resistance of Saccharomyces cerevisiae Cells to Dehydration–Rehydration

2019

Anhydrobiosis is a unique state of live organisms in which their metabolism is temporary reversibly suspended as the result of strong dehydration of their cells. This state is widely used currently during large-capacity production of active dry baker&rsquo

0106 biological sciencesLithocholic acidSaccharomyces cerevisiaePlant ScienceMitochondrion01 natural sciencesBiochemistry Genetics and Molecular Biology (miscellaneous)<i>Saccharomyces cerevisiae</i>03 medical and health scienceschemistry.chemical_compound010608 biotechnologymedicinedehydration–rehydrationDehydrationCryptobiosis030304 developmental biologylcsh:TP500-6600303 health sciencesbiologyChemistryMetabolismlcsh:Fermentation industries. Beverages. Alcoholanhydrobiosismedicine.diseasebiology.organism_classificationYeastmitochondriaMembranelithocholic acidBiochemistryFood ScienceFermentation
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AM fungal exudates activate MAP kinases in plant cells in dependence from cytosolic Ca2+ increase

2011

International audience; The molecular dialogue occurring prior to direct contact between the fungal and plant partners of arbuscular-mycorrhizal (AM) symbioses begins with the release of fungal elicitors, so far only partially identified chemically, which can activate specific signaling pathways in the host plant. We show here that the activation of MAPK is also induced by exudates of germinating spores of Gigaspora margarita in cultured cells of the non-leguminous species tobacco (Nicotiana tabacum), as well as in those of the model legume Lotus japonicus. MAPK activity peaked about 15 min after the exposure of the host cells to the fungal exudates (FE). FE were also responsible for a rapi…

0106 biological sciencesMAPK/ERK pathwayTime FactorsMAP Kinase Signaling SystemPhysiologyNicotiana tabacumLotus japonicusPlant ScienceComplex MixturesBiology01 natural sciences03 medical and health sciencesPlant CellsTobaccoBotanyGenetics[SDV.BV]Life Sciences [q-bio]/Vegetal BiologyGlomeromycotaSymbiosisNicotiana plumbaginifoliaPlant Proteins030304 developmental biologyMitogen-Activated Protein Kinase Kinasesarbuscular-mycorrhizal fungi0303 health sciencesdiffusible factorcalciumKinasefungiArbuscular-mycorrhizal fungi; Signaling; Diffusible factor; MAPK; Calciumfood and beveragesSpores FungalPlant cellbiology.organism_classificationMAPKsym pathwayCell biologyCytosolCell cultureLotus[SDE.BE]Environmental Sciences/Biodiversity and Ecologysignaling010606 plant biology & botanyPlant Physiology and Biochemistry
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Survival cost of an early immune soliciting in nature.

2009

8 pages; International audience; If immune functions confer obvious benefits to hosts, life-history theory assumes that they also induce costs, leading to trade-offs between immunity and other fitness components. However, whether substantial fitness costs are associated with immune systems in the wild is debatable, as numerous factors may influence the costs and benefits associated with immune activation. Here, we explore the survival cost of immune deployment in postfledging birds. We injected Eurasian collared dove nestlings (Streptopelia decaocto) with antigens from Escherichia coli, and examined whether this immune challenge affected survival after fledging. To assess survival, birds we…

0106 biological sciencesMESH : Escherichia coliimmune defensesMESH : Bird Diseases[ SDV.IMM.IA ] Life Sciences [q-bio]/Immunology/Adaptive immunology01 natural sciencesMESH: Bird DiseasesPredationNesting BehaviorBody SizeMESH: AnimalsMESH: Nesting BehaviorEscherichia coli InfectionsMESH : Adaptation Physiological0303 health sciencesbiologyMESH: Escherichia coli[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]StreptopeliaFledgeMESH : Antigens BacterialMESH : Immunity InnateAdaptation Physiological[ SDV.BID.EVO ] Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE][SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunologyMESH : Escherichia coli InfectionsMESH: Survival AnalysisMESH: Immunity InnateGeneral Agricultural and Biological Sciencessurvival.Immune activationfitness costMESH : Body SizeMESH : Nesting Behavior010603 evolutionary biologysurvivalBirds03 medical and health sciencesImmune systemAntigenImmunityGeneticsEscherichia coliAnimalsColumbidaeEcology Evolution Behavior and SystematicsMESH: Escherichia coli Infections030304 developmental biologyMESH: ColumbidaeAntigens BacterialMESH: Body SizeBird Diseasesbiology.organism_classificationMESH: Adaptation PhysiologicalSurvival AnalysisImmunity Innatefree-ranging vertebrateImmunologybacteriaMESH : AnimalsMESH : Survival AnalysisMESH : ColumbidaeMESH: Antigens BacterialFitness cost
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Diversifying selection on MHC class I in the house sparrow (Passer domesticus).

2009

10 pages; International audience; Genes of the major histocompatibility complex (MHC) are the most polymorphic loci known in vertebrates. Two main hypotheses have been put forward to explain the maintenance of MHC diversity: pathogen-mediated selection and MHC-based mate choice. Host-parasite interactions can maintain MHC diversity via frequency-dependent selection, heterozygote advantage, and diversifying selection (spatially and/or temporally heterogeneous selection). In this study, we wished to investigate the nature of selection acting on the MHC class I across spatially structured populations of house sparrows (Passer domesticus) in France. To infer the nature of the selection, we comp…

0106 biological sciencesMESH : Gene FlowMESH: Selection (Genetics)MESH: GeographyGenes MHC Class IMESH: Genetic MarkersBalancing selectionMESH : Microsatellite Repeats[ SDV.IMM.IA ] Life Sciences [q-bio]/Immunology/Adaptive immunology01 natural sciencesmicrosatellitesMESH: SparrowsMESH : Genetic MarkersMESH: AnimalsMESH: Genetic VariationMESH: Evolution MolecularGenetics0303 health scienceseducation.field_of_studyGeographybiology[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]MESH : GeographyMESH: Genes MHC Class I[ SDE.MCG ] Environmental Sciences/Global Changes[ SDV.BID.EVO ] Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE][SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunologyMate choiceMESH: Stochastic ProcessesMHC class IMESH : MutationSparrowsGene FlowGenetic MarkersMESH: Mutationbalancing selection[SDE.MCG]Environmental Sciences/Global ChangesPopulationMESH : Genetic DriftMESH: Genetics Populationchemical and pharmacologic phenomenaMESH : Stochastic ProcessesMajor histocompatibility complex010603 evolutionary biologyMESH : Genes MHC Class IEvolution Molecular03 medical and health sciencesMESH : Genetic VariationMHC class IGeneticsPasser domesticusMESH : Selection (Genetics)AnimalsMESH : Evolution MolecularSelection GeneticMESH: Genetic DrifteducationAllelesMESH: Gene FlowEcology Evolution Behavior and SystematicsSelection (genetic algorithm)030304 developmental biologyLocal adaptationIsolation by distanceStochastic Processes[ SDE.BE ] Environmental Sciences/Biodiversity and Ecologyhouse sparrowMESH: AllelesGenetic DriftGenetic Variationdiversifying selectionPasser domesticus.[ SDV.GEN.GA ] Life Sciences [q-bio]/Genetics/Animal geneticsMESH : Genetics Population[SDE.ES]Environmental Sciences/Environmental and Society[SDV.GEN.GA]Life Sciences [q-bio]/Genetics/Animal geneticsGenetics PopulationEvolutionary biologyMutationbiology.proteinMESH: Microsatellite RepeatsMESH : AnimalsMESH : Sparrows[SDE.BE]Environmental Sciences/Biodiversity and EcologyMESH : Alleles[ SDE.ES ] Environmental Sciences/Environmental and SocietyMicrosatellite Repeats
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Reverse-engineering the Arabidopsis thaliana transcriptional network under changing environmental conditions

2009

46 pages, 4 tables, 6 figures, 3 additinoal files.

0106 biological sciencesMESH: Genome PlantArabidopsis thalianaGene regulatory networkArabidopsis01 natural sciencesTranscriptomeGene Expression Regulation PlantArabidopsisMESH: Gene Expression Regulation DevelopmentalCluster AnalysisGene Regulatory NetworksMESH: ArabidopsisMESH: EcosystemMESH: Models GeneticOligonucleotide Array Sequence AnalysisMESH: Gene Regulatory NetworksGenetics0303 health sciencesMESH: Stress MechanicalbiologyMESH: Genomicsfood and beveragesGene Expression Regulation DevelopmentalGenomicsPhenotypeAlgorithmsGenome PlantMESH: MutationSystems biologyGenomicsMESH: AlgorithmsComputational biologyMESH: Arabidopsis ProteinsMESH: Phenotype03 medical and health sciencesMESH: Gene Expression Profiling[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyMESH: Gene Expression Regulation PlantEcosystem030304 developmental biologyModels GeneticMicroarray analysis techniquesArabidopsis ProteinsGene Expression ProfilingResearchfungiRobustness (evolution)biology.organism_classificationMESH: Cluster AnalysisGene expression profilingMutationMESH: Oligonucleotide Array Sequence AnalysisStress Mechanical010606 plant biology & botany
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The Chlamydomonas genome reveals the evolution of key animal and plant functions

2007

Chlamydomonas reinhardtii is a unicellular green alga whose lineage diverged from land plants over 1 billion years ago. It is a model system for studying chloroplast-based photosynthesis, as well as the structure, assembly, and function of eukaryotic flagella (cilia), which were inherited from the common ancestor of plants and animals, but lost in land plants. We sequenced the ∼120-megabase nuclear genome of Chlamydomonas and performed comparative phylogenomic analyses, identifying genes encoding uncharacterized proteins that are likely associated with the function and biogenesis of chloroplasts or eukaryotic flagella. Analyses of the Chlamydomonas genome advance our understanding of the a…

0106 biological sciencesMESH: Sequence Analysis DNAMESH: Algal ProteinsChloroplastsProteomeMESH: PlantsChlamydomonas reinhardtii01 natural sciencesGenomeMESH: Membrane Transport ProteinsDNA AlgalMESH: DNA AlgalMESH: AnimalsGoniumPhotosynthesisMESH: PhylogenyMESH: PhotosynthesisPhylogenyGenetics0303 health sciencesGenomeMultidisciplinarybiologyMESH: Genomicsfood and beveragesGenomicsPlantsBiological EvolutionMESH: Genes[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry Molecular Biology/Biomolecules [q-bio.BM]MESH: ProteomeFlagellaMultigene FamilyMESH: Computational BiologyMESH: Chlamydomonas reinhardtiiNuclear geneMolecular Sequence Data[SDV.BC]Life Sciences [q-bio]/Cellular BiologyFlagellumMESH: FlagellaArticle03 medical and health sciencesIntraflagellar transportMESH: EvolutionAnimalsMESH: Genome[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry Molecular Biology/Biochemistry [q-bio.BM]Gene[SDV.BC] Life Sciences [q-bio]/Cellular Biology030304 developmental biologyMESH: Molecular Sequence DataMESH: ChloroplastsAlgal ProteinsChlamydomonasComputational BiologyMembrane Transport ProteinsSequence Analysis DNAbiology.organism_classificationGenesMESH: Multigene FamilyChlamydomonas reinhardtii010606 plant biology & botany
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Spatial monitoring of gene activity in extraradical and intraradical developmental stages of arbuscular mycorrhizal fungi by direct fluorescent in si…

2008

International audience; Gene expression profiling based on tissue extracts gives only limited information about genes associated with complex developmental processes such as those implicated in fungal interactions with plant roots during arbuscular mycorrhiza development and function. To overcome this drawback, a direct fluorescent in situ RT-PCR methodology was developed for spatial mapping of gene expression in different presymbiotic and symbiotic structures of an arbuscular mycorrhizal fungus. Transcript detection was optimized by targeting the LSU rRNA gene of Glomus intraradices and monitoring expression of a stearoyl-CoA-desaturase gene that is consistently expressed at high levels in…

0106 biological sciencesMYCORHIZES A ARBUSCULESGENE EXPRESSIONHyphaGLOMUS INTRARADICESDIRECT FLUORESCENT IN SITU RT-PCR01 natural sciencesMicrobiologyPlant RootsARBUSCULAR MYCORRHIZAL FUNGIFungal ProteinsSUPEROXIDE DISMUTASE03 medical and health sciencesFungal StructuresGene Expression Regulation FungalMycorrhizaeBotanyGene expressionGeneticsMedicagoCONFOCAL MICROSCOPYGene030304 developmental biologyDNA PrimersFluorescent DyesPeptidylprolyl isomerase0303 health sciences[SDV.GEN]Life Sciences [q-bio]/GeneticsMicroscopy ConfocalbiologyPEPTIDYLPROPYL ISOMERASEReverse Transcriptase Polymerase Chain ReactionGene Expression ProfilingfungiSYMBIOSISGene Expression Regulation DevelopmentalPeptidylprolyl Isomerasebiology.organism_classificationMedicago truncatulaCell biologyArbuscular mycorrhizaGene expression profilingSTEAROYL-CoA-DESATURASEXanthenesMEDICAGO TRUNCATULAStearoyl-CoA Desaturase010606 plant biology & botany
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