Search results for "etiikka"

Omission of Quality Software Development Practices : A Systematic Literature Review

2018

Software deficiencies are minimized by utilizing recommended software development and quality assurance practices. However, these recommended practices (i.e., quality practices) become ineffective if software professionals purposefully ignore them. Conducting a systematic literature review (n = 4,838), we discovered that only a small number of previous studies, within software engineering and information systems literature, have investigated the omission of quality practices. These studies explain the omission of quality practices mainly as a result of organizational decisions and trade-offs made under resource constraints or market pressure. However, our study indicates that different aspe…

Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults

2018

Background: DNA methylation at the GFI1-locus has been repeatedly associated with exposure to smoking from the foetal period onwards. We explored whether DNA methylation may be a mechanism that links exposure to maternal prenatal smoking with offspring's adult cardio-metabolic health.Methods: We meta-analysed the association between DNA methylation at GFI1-locus with maternal prenatal smoking, adult own smoking, and cardio-metabolic phenotypes in 22 population-based studies from Europe, Australia, and USA (n= 18,212). DNA methylation at the GFI1-locus was measured in whole-blood. Multivariable regression models were fitted to examine its association with exposure to prenatal and own adult s…

Objectively measured physical activity profile and cognition in Finnish elderly twins

2018

Introduction We studied whether objectively measured physical activity (PA) and sedentary behavior (SB) are associated with cognition in Finnish elderly twins. Methods This cross-sectional study comprised twins born in Finland from 1940 to 1944 in the Older Finnish Twin Cohort (mean age, 72.9 years; 726 persons). From 2014 to 2016, cognition was assessed with a validated telephonic interview, whereas PA was measured with a waist-worn accelerometer. Results In between-family models, SB and light physical activity had significant linear associations with cognition after adjusting for age, sex, wearing time, education level, body mass index, and living condition (SB: β-estimate, −0.21 [95% con…

Responses to vulnerability : care ethics and the technologisation of eldercare

2020

This article argues for a re-conceptualisation of care relations and uses the re-conceptualisation to scrutinise the way in which technology is adopted in eldercare practices. First, it draws on the definition of care as attentiveness to vulnerability, as used in the tradition of care ethics. Second, it specifies four essential aspects of care relations: relationality, dyadic mutuality, corporeality and devotion. Third, using socio-technical and phenomenological perspectives, care relations are contrasted with the idea of intertwining technological and human actors in care practices. Finally, using two adaptations of telecare as examples, the essential aspects of care relations are shown to…

Comparing RADseq and microsatellites for estimating genetic diversity and relatedness : Implications for brown trout conservation

2019

The conservation and management of endangered species requires information on their genetic diversity, relatedness and population structure. The main genetic markers applied for these questions are microsatellites and single nucleotide polymorphisms (SNPs), the latter of which remain the more resource demanding approach in most cases. Here, we compare the performance of two approaches, SNPs obtained by restriction-site-associated DNA sequencing (RADseq) and 16 DNA microsatellite loci, for estimating genetic diversity, relatedness and genetic differentiation of three, small, geographically close wild brown trout (Salmo trutta) populations and a regionally used hatchery strain. The genetic di…

In vitro sulfonation of 7-hydroxycoumarin derivatives in liver cytosol of human and six animal species

2020

Sulfonation is an important high affinity elimination pathway for phenolic compounds.In this study sulfonation of 7-hydroxycoumarin and 13 its derivatives were evaluated in liver cytosols of human and six animal species. 7-hydroxycoumarin and its derivatives are strongly fluorescent, and their sulfate conjugates are nonfluorescent at excitation 405 nm and emission 460 nm. A convenient fluorescence based kinetic assay of sulfonation was established.The sulfonation rate of most of the 7-hydroxycoumarin derivatives was low in liver cytosol of human and pig, whereas it was high with most compounds in dog and intermediate in rat, mouse, rabbit, and sheep. Sulfonation of the 7-hydroxycoumarin der…

Fronēsis hermeneuttisena hyveenä : Aristoteles, Heidegger, Gadamer

2014

Martin Heidegger länsimaisen metafysiikan rajalla teoksessa "Aus einem Gespräch von der Sprache"

2008

Tanssiteoksen kohtaaminen Martin Heideggerin taiteenontologian avaamassa ulottuvuudessa

2014

Pro gradu- tutkielmani on filosofinen tutkimus tanssiteoksesta ja tanssiteoksen kohtaamisesta. Tutkielmani tarkoitus on tutkia tanssiteoksen tapahtumaluontoista olemusta, tanssiteoksessa tapahtuvaa tanssin liikkeen merkitysrakennetta sekä tanssiteoksen kohtaamisen problematiikka Martin Heideggerin (1889- 1976) filosofian ja taiteenontologian avaamassa ulottuvuudessa. Tutkielmassani pyrin luomaan tanssiteoksen kohtaamiselle tulkintahorisontin, jossa tanssiteos tulee kohdatuksi estetiikan traditioon pohjautuvasta taideteoksen käsittämisen ja kohtaamisen tavasta poikkeavalla tavalla. Tutkielmani tarkoitus on luoda tanssiteoksen kohtaamiselle sellainen tulkintahorisontti, jossa kysymykset tanss…

History in corporate social responsibility : Reviewing and setting an agenda

2018

The integration of historical reasoning and corporate social responsibility (CSR) theorising has recently received remarkable cross-disciplinary attention by business historians and CSR scholars. But has there been a meaningful interdisciplinary conversation? Motivated by this question that presumes significant limitations in the current integration, I survey existing research for the purpose of sketching and shaping historical CSR studies, ie an umbrella that brings together diverse approaches to history and CSR theorising. Drawing from the recent efforts to establish historical methodologies in organisation studies, I first reconcile discrepant disciplinary and field-level traditions to c…